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AKT in cancer: new molecular insights and advances in drug development
Mundi, Prabhjot S., Sachdev, Jasgit, McCourt, Carolyn, Kalinsky, Kevin
Published in British journal of clinical pharmacology (01.10.2016)
Published in British journal of clinical pharmacology (01.10.2016)
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Journal Article
Phase 1 study of MRX34, a liposomal miR-34a mimic, in patients with advanced solid tumours
Hong, David S., Kang, Yoon-Koo, Borad, Mitesh, Sachdev, Jasgit, Ejadi, Samuel, Lim, Ho Yeong, Brenner, Andrew J., Park, Keunchil, Lee, Jae-Lyun, Kim, Tae-You, Shin, Sangjoon, Becerra, Carlos R., Falchook, Gerald, Stoudemire, Jay, Martin, Desiree, Kelnar, Kevin, Peltier, Heidi, Bonato, Vinicius, Bader, Andreas G., Smith, Susan, Kim, Sinil, O’Neill, Vincent, Beg, Muhammad S.
Published in British journal of cancer (26.05.2020)
Published in British journal of cancer (26.05.2020)
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Journal Article
First-in-Human Study of Mivebresib (ABBV-075), an Oral Pan-Inhibitor of Bromodomain and Extra Terminal Proteins, in Patients with Relapsed/Refractory Solid Tumors
Piha-Paul, Sarina A., Sachdev, Jasgit C., Barve, Minal, LoRusso, Patricia, Szmulewitz, Russell, Patel, Sapna Pradyuman, Lara, Primo N., Chen, Xiaotian, Hu, Beibei, Freise, Kevin J., Modi, Dimple, Sood, Anjla, Hutti, Jessica E., Wolff, Johannes, O'Neil, Bert H.
Published in Clinical cancer research (01.11.2019)
Published in Clinical cancer research (01.11.2019)
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Journal Article
Safety and Antitumor Activity of Pembrolizumab in Patients with Estrogen Receptor–Positive/Human Epidermal Growth Factor Receptor 2–Negative Advanced Breast Cancer
Rugo, Hope S., Delord, Jean-Pierre, Im, Seock-Ah, Ott, Patrick A., Piha-Paul, Sarina A., Bedard, Philippe L., Sachdev, Jasgit, Tourneau, Christophe Le, van Brummelen, Emilie M.J., Varga, Andrea, Salgado, Roberto, Loi, Sherene, Saraf, Sanatan, Pietrangelo, Dina, Karantza, Vassiliki, Tan, Antoinette R.
Published in Clinical cancer research (15.06.2018)
Published in Clinical cancer research (15.06.2018)
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Journal Article
First-in-Human Study of PF-06647020 (Cofetuzumab Pelidotin), an Antibody–Drug Conjugate Targeting Protein Tyrosine Kinase 7, in Advanced Solid Tumors
Maitland, Michael L., Sachdev, Jasgit C., Sharma, Manish R., Moreno, Victor, Boni, Valentina, Kummar, Shivaani, Stringer-Reasor, Erica, Lakhani, Nehal, Moreau, Allison R., Xuan, Dawei, Li, Ray, Powell, Eric L., Jackson-Fisher, Amy, Bowers, Michelle, Alekar, Shilpa, Xin, Xiaohua, Tolcher, Anthony W., Calvo, Emiliano
Published in Clinical cancer research (15.08.2021)
Published in Clinical cancer research (15.08.2021)
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Journal Article
Correlation between Ferumoxytol Uptake in Tumor Lesions by MRI and Response to Nanoliposomal Irinotecan in Patients with Advanced Solid Tumors: A Pilot Study
Ramanathan, Ramesh K., Korn, Ronald L., Raghunand, Natarajan, Sachdev, Jasgit C., Newbold, Ronald G., Jameson, Gayle, Fetterly, Gerald J., Prey, Joshua, Klinz, Stephan G., Kim, Jaeyeon, Cain, Jason, Hendriks, Bart S., Drummond, Daryl C., Bayever, Eliel, Fitzgerald, Jonathan B.
Published in Clinical cancer research (15.07.2017)
Published in Clinical cancer research (15.07.2017)
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Journal Article
Phase I Study of PSMA-Targeted Docetaxel-Containing Nanoparticle BIND-014 in Patients with Advanced Solid Tumors
Von Hoff, Daniel D., Mita, Monica M., Ramanathan, Ramesh K., Weiss, Glen J., Mita, Alain C., LoRusso, Patricia M., Burris, Howard A., Hart, Lowell L., Low, Susan C., Parsons, Donald M., Zale, Stephen E., Summa, Jason M., Youssoufian, Hagop, Sachdev, Jasgit C.
Published in Clinical cancer research (01.07.2016)
Published in Clinical cancer research (01.07.2016)
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Journal Article
Phase I study of liposomal irinotecan in patients with metastatic breast cancer: findings from the expansion phase
Sachdev, Jasgit C., Munster, Pamela, Northfelt, Donald W., Han, Hyo Sook, Ma, Cynthia, Maxwell, Fiona, Wang, Tiffany, Belanger, Bruce, Zhang, Bin, Moore, Yan, Thiagalingam, Arunthathi, Anders, Carey
Published in Breast cancer research and treatment (01.02.2021)
Published in Breast cancer research and treatment (01.02.2021)
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Journal Article
Phase I study of imalumab (BAX69), a fully human recombinant antioxidized macrophage migration inhibitory factor antibody in advanced solid tumours
Mahalingam, Devalingam, Patel, Manish R., Sachdev, Jasgit C., Hart, Lowell L., Halama, Niels, Ramanathan, Ramesh K., Sarantopoulos, John, Völkel, Dirk, Youssef, Ashraf, Jong, Floris A., Tsimberidou, Apostolia Maria
Published in British journal of clinical pharmacology (01.09.2020)
Published in British journal of clinical pharmacology (01.09.2020)
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Journal Article
Overcoming Taxane Resistance: Preclinical and Phase 1 Studies of Relacorilant, a Selective Glucocorticoid Receptor Modulator, with Nab-Paclitaxel in Solid Tumors
Munster, Pamela N., Greenstein, Andrew E., Fleming, Gini F., Borazanci, Erkut, Sharma, Manish R., Custodio, Joseph M., Tudor, Iulia Cristina, Pashova, Hristina I., Shepherd, Stacie Peacock, Grauer, Andreas, Sachdev, Jasgit C.
Published in Clinical cancer research (02.08.2022)
Published in Clinical cancer research (02.08.2022)
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Journal Article
Phase I Basket Study of Taselisib, an Isoform-Selective PI3K Inhibitor, in Patients with PIK3CA -Mutant Cancers
Jhaveri, Komal, Chang, Matthew T., Juric, Dejan, Saura, Cristina, Gambardella, Valentina, Melnyk, Anton, Patel, Manish R., Ribrag, Vincent, Ma, Cynthia X., Aljumaily, Raid, Bedard, Philippe L., Sachdev, Jasgit C., Dunn, Lara, Won, Helen, Bond, John, Jones, Surai, Savage, Heidi M., Scaltriti, Maurizio, Wilson, Timothy R., Wei, Michael C., Hyman, David M.
Published in Clinical cancer research (15.01.2021)
Published in Clinical cancer research (15.01.2021)
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Journal Article
Safety, Pharmacokinetics, and Pharmacodynamics of a Humanized Anti-Semaphorin 4D Antibody, in a First-In-Human Study of Patients with Advanced Solid Tumors
Patnaik, Amita, Weiss, Glen J., Leonard, John E., Rasco, Drew Warren, Sachdev, Jasgit C., Fisher, Terrence L., Winter, Laurie A., Reilly, Christine, Parker, Robert B., Mutz, Danielle, Blaydorn, Lisa, Tolcher, Anthony W., Zauderer, Maurice, Ramanathan, Ramesh K.
Published in Clinical cancer research (15.02.2016)
Published in Clinical cancer research (15.02.2016)
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Journal Article
Safety, antitumor activity, and pharmacokinetics of dostarlimab, an anti-PD-1, in patients with advanced solid tumors: a dose–escalation phase 1 trial
Patnaik, Amita, Weiss, Glen J., Rasco, Drew W., Blaydorn, Lisa, Mirabella, Amy, Beeram, Murali, Guo, Wei, Lu, Sharon, Danaee, Hadi, McEachern, Kristen, Im, Ellie, Sachdev, Jasgit C.
Published in Cancer chemotherapy and pharmacology (01.01.2022)
Published in Cancer chemotherapy and pharmacology (01.01.2022)
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Journal Article
A first-in-human, phase 1, dose-escalation study of ABBV-176, an antibody-drug conjugate targeting the prolactin receptor, in patients with advanced solid tumors
Lemech, Charlotte, Woodward, Natasha, Chan, Nancy, Mortimer, Joanne, Naumovski, Louie, Nuthalapati, Silpa, Tong, Bo, Jiang, Fang, Ansell, Peter, Ratajczak, Christine K., Sachdev, Jasgit
Published in Investigational new drugs (01.12.2020)
Published in Investigational new drugs (01.12.2020)
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Journal Article
Phase 1 study of TTC-352 in patients with metastatic breast cancer progressing on endocrine and CDK4/6 inhibitor therapy
Dudek, Arkadiusz Z., Liu, Li C., Fischer, James H., Wiley, Elizabeth L., Sachdev, Jasgit C., Bleeker, Jonathan, Hurley, Randolph W., Tonetti, Debra A., Thatcher, Gregory R. J., Venuti, Robert P., O’Regan, Ruth M.
Published in Breast cancer research and treatment (01.10.2020)
Published in Breast cancer research and treatment (01.10.2020)
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Journal Article
IOLite: phase 1b trial of doublet/triplet combinations of dostarlimab with niraparib, carboplatin–paclitaxel, with or without bevacizumab in patients with advanced cancer
Yap, Timothy A, Bessudo, Alberto, Hamilton, Erika, Sachdev, Jasgit, Patel, Manish R, Rodon, Jordi, Evilevitch, Lena, Duncan, Meghan, Guo, Wei, Kumar, Sujatha, Lu, Sharon, Dezube, Bruce J, Gabrail, Nashat
Published in Journal for immunotherapy of cancer (01.03.2022)
Published in Journal for immunotherapy of cancer (01.03.2022)
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Journal Article
Caveolin-1: Oncogenic role in breast cancer? Clues from molecular profiling
Feldman, Rebecca, Gatalica, Zoran, Reddy, Sandeep K., Castro, Michael, Sachdev, Jasgit C.
Published in Journal of clinical oncology (01.10.2015)
Published in Journal of clinical oncology (01.10.2015)
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Journal Article
Patients with recurrent gynecologic cancers and Wnt activating mutations demonstrated greater clinical benefit when treated with DKN-01 therapy
Arend, Rebecca, Castro, Cesar, Matulonis, Ursula, Hamilton, Erika, Gunderson, Camille, Lybarger, Kristopher, Goodman, Howard, Duska, Linda, Mahdi, Haider, ElNaggar, Adam, Kagey, Michael, Barroilhet, Lisa, Bradley, William, Sachdev, Jasgit, Sirard, Cynthia, O'Malley, David, Birrer, Michael
Published in Gynecologic oncology (01.08.2021)
Published in Gynecologic oncology (01.08.2021)
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Journal Article