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Diminished allergic disease in patients with STAT3 mutations reveals a role for STAT3 signaling in mast cell degranulation
Siegel, Andrea M., Stone, Kelly D., Cruse, Glenn, Lawrence, Monica G., Olivera, Ana, Jung, Mi-yeon, Barber, John S., Freeman, Alexandra F., Holland, Steven M., O'Brien, Michelle, Jones, Nina, Wisch, Laura B., Kong, Heidi H., Desai, Avanti, Farber, Orly, Gilfillan, Alasdair M., Rivera, Juan, Milner, Joshua D.
Published in Journal of allergy and clinical immunology (01.12.2013)
Published in Journal of allergy and clinical immunology (01.12.2013)
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Journal Article
A STAT3 palmitoylation cycle promotes TH17 differentiation and colitis
Zhang, Mingming, Zhou, Lixing, Xu, Yuejie, Yang, Min, Xu, Yilai, Komaniecki, Garrison Paul, Kosciuk, Tatsiana, Chen, Xiao, Lu, Xuan, Zou, Xiaoping, Linder, Maurine E., Lin, Hening
Published in Nature (London) (15.10.2020)
Published in Nature (London) (15.10.2020)
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Journal Article
Phase 1, open-label, dose-escalation, and pharmacokinetic study of STAT3 inhibitor OPB-31121 in subjects with advanced solid tumors
Bendell, Johanna C., Hong, David S., Burris, Howard A., Naing, Aung, Jones, Suzanne F., Falchook, Gerald, Bricmont, Patricia, Elekes, Agnes, Rock, Edwin P., Kurzrock, Razelle
Published in Cancer chemotherapy and pharmacology (01.07.2014)
Published in Cancer chemotherapy and pharmacology (01.07.2014)
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Journal Article
Unexpected implications of STAT3 acetylation revealed by genetic encoding of acetyl-lysine
Belo, Yael, Mielko, Zachery, Nudelman, Hila, Afek, Ariel, Ben-David, Oshrit, Shahar, Anat, Zarivach, Raz, Gordan, Raluca, Arbely, Eyal
Published in Biochimica et biophysica acta. General subjects (01.09.2019)
Published in Biochimica et biophysica acta. General subjects (01.09.2019)
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Journal Article
Adipocyte-derived kynurenine promotes obesity and insulin resistance by activating the AhR/STAT3/IL-6 signaling
Huang, Teng, Song, Jia, Gao, Jia, Cheng, Jia, Xie, Hao, Zhang, Lu, Wang, Yu-Han, Gao, Zhichao, Wang, Yi, Wang, Xiaohui, He, Jinhan, Liu, Shiwei, Yu, Qilin, Zhang, Shu, Xiong, Fei, Zhou, Qing, Wang, Cong-Yi
Published in Nature communications (17.06.2022)
Published in Nature communications (17.06.2022)
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Journal Article
Selenomethionine modulates the JAK2 / STAT3 / A20 pathway through oxidative stress to alleviate LPS-induced pyroptosis and inflammation in chicken hearts
Lei, Yutian, Sun, Wenying, Xu, Tong, Shan, Jianhua, Gao, Meichen, Lin, Hongjin
Published in Biochimica et biophysica acta. General subjects (01.04.2024)
Published in Biochimica et biophysica acta. General subjects (01.04.2024)
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Journal Article
Paracrine IL-6 signaling mediates the effects of pancreatic stellate cells on epithelial-mesenchymal transition via Stat3/Nrf2 pathway in pancreatic cancer cells
Wu, Yuan Seng, Chung, Ivy, Wong, Won Fen, Masamune, Atsushi, Sim, Maw Shin, Looi, Chung Yeng
Published in Biochimica et biophysica acta. General subjects (01.02.2017)
Published in Biochimica et biophysica acta. General subjects (01.02.2017)
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Journal Article
STAT3 as a newly emerging target in colorectal cancer therapy: Tumorigenesis, therapy response, and pharmacological/nanoplatform strategies
Hashemi, Mehrdad, Abbaszadeh, Sahar, Rashidi, Mohsen, Amini, Nafisesadat, Talebi Anaraki, Kasra, Motahhary, Motahhar, Khalilipouya, Ensi, Harif Nashtifani, Abdorrahman, Shafiei, Sasan, Ramezani Farani, Marzieh, Nabavi, Noushin, Salimimoghadam, Shokooh, Aref, Amir Reza, Raesi, Rasoul, Taheriazam, Afshin, Entezari, Maliheh, Zha, Wenliang
Published in Environmental research (15.09.2023)
Published in Environmental research (15.09.2023)
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Journal Article
Mesenchymal stem cells‐derived IL‐6 promotes invasion and metastasis of oral squamous cell carcinoma via JAK‐STAT3 signalling
Liu, Chuanxia, Zhou, Jinhan, Zhang, Shanshan, Fu, Ji, Li, Yining, Hao, Yilong, Yuan, Jian, Tang, Fan, Ge, Weili, He, Hong, Chen, Qianming
Published in Oral diseases (01.05.2024)
Published in Oral diseases (01.05.2024)
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Journal Article
TLR9-Targeted STAT3 Silencing Abrogates Immunosuppressive Activity of Myeloid-Derived Suppressor Cells from Prostate Cancer Patients
Hossain, Dewan M. S., Pal, Sumanta K., Moreira, Dayson, Duttagupta, Priyanka, Zhang, Qifang, Won, Haejung, Jones, Jeremy, D'Apuzzo, Massimo, Forman, Stephen, Kortylewski, Marcin
Published in Clinical cancer research (15.08.2015)
Published in Clinical cancer research (15.08.2015)
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Journal Article
A First‐in‐Human Phase I Study of OPB‐111077, a Small‐Molecule STAT3 and Oxidative Phosphorylation Inhibitor, in Patients with Advanced Cancers
Tolcher, Anthony, Flaherty, Keith, Shapiro, Geoffrey I., Berlin, Jordan, Witzig, Thomas, Habermann, Thomas, Bullock, Andrea, Rock, Edwin, Elekes, Agnes, Lin, Chester, Kostic, Dusan, Ohi, Naoto, Rasco, Drew, Papadopoulos, Kyriakos P., Patnaik, Amita, Smith, Lon, Cote, Gregory M.
Published in The oncologist (Dayton, Ohio) (01.06.2018)
Published in The oncologist (Dayton, Ohio) (01.06.2018)
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Journal Article
FAP Promotes Immunosuppression by Cancer-Associated Fibroblasts in the Tumor Microenvironment via STAT3–CCL2 Signaling
Yang, Xuguang, Lin, Yuli, Shi, Yinghong, Li, Bingji, Liu, Weiren, Yin, Wei, Dang, Yongjun, Chu, Yiwei, Fan, Jia, He, Rui
Published in Cancer research (Chicago, Ill.) (15.07.2016)
Published in Cancer research (Chicago, Ill.) (15.07.2016)
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Journal Article
The S52F FOXF1 Mutation Inhibits STAT3 Signaling and Causes Alveolar Capillary Dysplasia
Pradhan, Arun, Dunn, Andrew, Ustiyan, Vladimir, Bolte, Craig, Wang, Guolun, Whitsett, Jeffrey A., Zhang, Yufang, Porollo, Alexey, Hu, Yueh-Chiang, Xiao, Rui, Szafranski, Przemyslaw, Shi, Donglu, Stankiewicz, Pawel, Kalin, Tanya V., Kalinichenko, Vladimir V.
Published in American journal of respiratory and critical care medicine (15.10.2019)
Published in American journal of respiratory and critical care medicine (15.10.2019)
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Journal Article
STAT3 Hyperactivation Due to SOCS3 Deletion in Murine Osteocytes Accentuates Responses to Exercise‐ and Load‐Induced Bone Formation
McGregor, Narelle E, Walker, Emma C, Chan, Audrey SM, Poulton, Ingrid J, Cho, Ellie H‐J, Windahl, Sara H, Sims, Natalie A
Published in Journal of bone and mineral research (01.03.2022)
Published in Journal of bone and mineral research (01.03.2022)
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Journal Article
AMPK-induced novel phosphorylation of RUNX1 inhibits STAT3 activation and overcome imatinib resistance in chronic myelogenous leukemia (CML) subjects
Gayatri, Meher Bolisetti, Kancha, Rama Krishna, Behera, Abhayananda, Patchva, Dorababu, Velugonda, Nagaraj, Gundeti, Sadasivudu, Reddy, Aramati Bindu Madhava
Published in Cell death discovery (30.10.2023)
Published in Cell death discovery (30.10.2023)
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Journal Article
SLAMF3 promotes Th17 differentiation and is reversed by iguratimod through JAK1/STAT3 pathway in primary Sjögren's syndrome
Hu, Peini, Cai, Juan, Yang, Chunshu, Xu, Lingling, Ma, Siyang, Song, Haining, Yang, Pingting
Published in International immunopharmacology (05.01.2024)
Published in International immunopharmacology (05.01.2024)
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Journal Article
Self‐Assembled/Drug‐Composed Nanomedicine for Synergistic Photonic Hyperthermia and Targeted Therapy of Breast Cancer by Inhibiting ERK, AKT, and STAT3 Signaling Cascades
He, Chao, Yu, Luodan, Ding, Li, Chen, Yu, Hao, Yongqiang
Published in Advanced functional materials (01.03.2020)
Published in Advanced functional materials (01.03.2020)
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Journal Article