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Impact of chronic dietary red meat, white meat, or non-meat protein on trimethylamine N-oxide metabolism and renal excretion in healthy men and women
Wang, Zeneng, Bergeron, Nathalie, Levison, Bruce S, Li, Xinmin S, Chiu, Sally, Jia, Xun, Koeth, Robert A, Li, Lin, Wu, Yuping, Tang, W H Wilson, Krauss, Ronald M, Hazen, Stanley L
Published in European heart journal (14.02.2019)
Published in European heart journal (14.02.2019)
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Journal Article
Shift to Fatty Substrate Utilization in Response to Sodium–Glucose Cotransporter 2 Inhibition in Subjects Without Diabetes and Patients With Type 2 Diabetes
Ferrannini, Ele, Baldi, Simona, Frascerra, Silvia, Astiarraga, Brenno, Heise, Tim, Bizzotto, Roberto, Mari, Andrea, Pieber, Thomas R., Muscelli, Elza
Published in Diabetes (New York, N.Y.) (01.05.2016)
Published in Diabetes (New York, N.Y.) (01.05.2016)
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Journal Article
Interaction Between the Sodium‐Glucose–Linked Transporter 2 Inhibitor Dapagliflozin and the Loop Diuretic Bumetanide in Normal Human Subjects
Wilcox, Christopher S., Shen, Wen, Boulton, David W., Leslie, Bruce R., Griffen, Steven C.
Published in Journal of the American Heart Association (20.02.2018)
Published in Journal of the American Heart Association (20.02.2018)
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Journal Article
Pharmacokinetics, Disposition, and Biotransformation of [14C]Omecamtiv Mecarbil in Healthy Male Subjects after a Single Intravenous or Oral Dose
Trivedi, Ashit, Wahlstrom, Jan, Mackowski, Mia, Dutta, Sandeep, Lee, Edward
Published in Drug metabolism and disposition (01.08.2021)
Published in Drug metabolism and disposition (01.08.2021)
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Journal Article
Safety, tolerability, and pharmacokinetics of oral baicalein tablets in healthy Chinese subjects: A single‐center, randomized, double‐blind, placebo‐controlled multiple‐ascending‐dose study
Li, Lijun, Gao, Hongzhi, Lou, Kun, Luo, Hongmei, Hao, Sheng, Yuan, Jing, Liu, Zeyuan, Dong, Ruihua
Published in Clinical and translational science (01.09.2021)
Published in Clinical and translational science (01.09.2021)
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Journal Article
Delineating the Role of Various Factors in Renal Disposition of Digoxin through Application of Physiologically Based Kidney Model to Renal Impairment Populations
Scotcher, Daniel, Jones, Christopher R., Galetin, Aleksandra, Rostami-Hodjegan, Amin
Published in The Journal of pharmacology and experimental therapeutics (01.03.2017)
Published in The Journal of pharmacology and experimental therapeutics (01.03.2017)
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Journal Article
Clinical Investigation of Metabolic and Renal Clearance Pathways Contributing to the Elimination of Fevipiprant Using Probenecid as Perpetrator
Weiss, H. Markus, Langenickel, Thomas, Cain, Meredith, Kulkarni, Swarupa, Shah, Bharti, Vemula, Janardhana, Rahmanzadeh, Gholamreza, Poller, Birk
Published in Drug metabolism and disposition (01.05.2021)
Published in Drug metabolism and disposition (01.05.2021)
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Journal Article
Influence of age on the absorption, metabolism, and excretion of cocoa flavanols in healthy subjects
Rodriguez‐Mateos, Ana, Cifuentes‐Gomez, Tania, Gonzalez‐Salvador, Isidro, Ottaviani, Javier I, Schroeter, Hagen, Kelm, Malte, Heiss, Christian, Spencer, Jeremy P. E
Published in Molecular nutrition & food research (01.08.2015)
Published in Molecular nutrition & food research (01.08.2015)
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Journal Article
Nanomedicines for kidney diseases
Williams, Ryan M., Jaimes, Edgar A., Heller, Daniel A.
Published in Kidney international (01.10.2016)
Published in Kidney international (01.10.2016)
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Journal Article
Effects of Pregnancy on the Pharmacokinetics of Metformin
Liao, Michael Z., Flood Nichols, Shannon K., Ahmed, Mahmoud, Clark, Shannon, Hankins, Gary D., Caritis, Steve, Venkataramanan, Raman, Haas, David, Quinney, Sara K., Haneline, Laura S., Tita, Alan T., Manuck, Tracy, Wang, Joanne, Thummel, Kenneth E., Brown, Linda Morris, Ren, Zhaoxia, Easterling, Thomas R., Hebert, Mary F.
Published in Drug metabolism and disposition (01.04.2020)
Published in Drug metabolism and disposition (01.04.2020)
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Journal Article
Mass Balance, Metabolism, and Excretion of Cenobamate, a New Antiepileptic Drug, After a Single Oral Administration in Healthy Male Subjects
Vernillet, Laurent, Greene, Stephen A., Kim, Hong Wook, Melnick, Susan M., Glenn, Kelli
Published in European journal of drug metabolism and pharmacokinetics (01.08.2020)
Published in European journal of drug metabolism and pharmacokinetics (01.08.2020)
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Journal Article
Coadministration of probenecid and cimetidine with mirogabalin in healthy subjects: A phase 1, randomized, open‐label, drug–drug interaction study
Tachibana, Masaya, Yamamura, Naotoshi, Atiee, George J., Hsu, Ching, Warren, Vance, He, Ling, Dishy, Victor, Zahir, Hamim
Published in British journal of clinical pharmacology (01.10.2018)
Published in British journal of clinical pharmacology (01.10.2018)
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Journal Article
Physiologically based pharmacokinetic modelling to predict exposure differences in healthy volunteers and subjects with renal impairment: Ceftazidime case study
Zhou, Li, Tong, Xiao, Sharma, Pradeep, Xu, Hongmei, Al‐Huniti, Nidal, Zhou, Diansong
Published in Basic & clinical pharmacology & toxicology (01.08.2019)
Published in Basic & clinical pharmacology & toxicology (01.08.2019)
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Journal Article
Novel Mechanism for Buffering Dietary Salt in Humans: Effects of Salt Loading on Skin Sodium, Vascular Endothelial Growth Factor C, and Blood Pressure
Selvarajah, Viknesh, Mäki-Petäjä, Kaisa M., Pedro, Liliana, Bruggraber, Sylvaine F.A., Burling, Keith, Goodhart, Anna K., Brown, Morris J., McEniery, Carmel M., Wilkinson, Ian B.
Published in Hypertension (Dallas, Tex. 1979) (01.11.2017)
Published in Hypertension (Dallas, Tex. 1979) (01.11.2017)
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Journal Article
Renal elimination of p-aminohippurate (PAH) in response to three days of biliary obstruction in the rat. The role of OAT1 and OAT3
Brandoni, Anabel, Anzai, Naohiko, Kanai, Yoshikatsu, Endou, Hitoshi, Torres, Adriana Mónica
Published in Biochimica et biophysica acta (01.07.2006)
Published in Biochimica et biophysica acta (01.07.2006)
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Journal Article
Drug-Induced Kidney Stones and Crystalline Nephropathy: Pathophysiology, Prevention and Treatment
Daudon, Michel, Frochot, Vincent, Bazin, Dominique, Jungers, Paul
Published in Drugs (New York, N.Y.) (01.02.2018)
Published in Drugs (New York, N.Y.) (01.02.2018)
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Journal Article
Pharmacokinetic and pharmacodynamic modelling for renal function dependent urinary glucose excretion effect of ipragliflozin, a selective sodium–glucose cotransporter 2 inhibitor, both in healthy subjects and patients with type 2 diabetes mellitus
Saito, Masako, Kaibara, Atsunori, Kadokura, Takeshi, Toyoshima, Junko, Yoshida, Satoshi, Kazuta, Kenichi, Ueyama, Eiji
Published in British journal of clinical pharmacology (01.08.2019)
Published in British journal of clinical pharmacology (01.08.2019)
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Journal Article