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Hyocholic acid species improve glucose homeostasis through a distinct TGR5 and FXR signaling mechanism
Zheng, Xiaojiao, Chen, Tianlu, Jiang, Runqiu, Zhao, Aihua, Wu, Qing, Kuang, Junliang, Sun, Dongnan, Ren, Zhenxing, Li, Mengci, Zhao, Mingliang, Wang, Shouli, Bao, Yuqian, Li, Huating, Hu, Cheng, Dong, Bing, Li, Defa, Wu, Jiayu, Xia, Jialin, Wang, Xuemei, Lan, Ke, Rajani, Cynthia, Xie, Guoxiang, Lu, Aiping, Jia, Weiping, Jiang, Changtao, Jia, Wei
Published in Cell metabolism (06.04.2021)
Published in Cell metabolism (06.04.2021)
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Journal Article
Suppressing the intestinal farnesoid X receptor/sphingomyelin phosphodiesterase 3 axis decreases atherosclerosis
Wu, Qing, Sun, Lulu, Hu, Xiaomin, Wang, Xuemei, Xu, Feng, Chen, Bo, Liang, Xianyi, Xia, Jialin, Wang, Pengcheng, Aibara, Daisuke, Zhang, Shaofei, Zeng, Guangyi, Yun, Chuyu, Yan, Yu, Zhu, Yicheng, Bustin, Michael, Zhang, Shuyang, Gonzalez, Frank J., Jiang, Changtao
Published in The Journal of clinical investigation (01.05.2021)
Published in The Journal of clinical investigation (01.05.2021)
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Journal Article
Human NACHT, LRR, and PYD domain–containing protein 3 (NLRP3) inflammasome activity is regulated by and potentially targetable through Bruton tyrosine kinase
Liu, Xiao, Pichulik, Tica, Wolz, Olaf-Oliver, Dang, Truong-Minh, Stutz, Andrea, Dillen, Carly, Delmiro Garcia, Magno, Kraus, Helene, Dickhöfer, Sabine, Daiber, Ellen, Münzenmayer, Lisa, Wahl, Silke, Rieber, Nikolaus, Kümmerle-Deschner, Jasmin, Yazdi, Amir, Franz-Wachtel, Mirita, Macek, Boris, Radsak, Markus, Vogel, Sebastian, Schulte, Berit, Walz, Juliane Sarah, Hartl, Dominik, Latz, Eicke, Stilgenbauer, Stephan, Grimbacher, Bodo, Miller, Lloyd, Brunner, Cornelia, Wolz, Christiane, Weber, Alexander N.R.
Published in Journal of allergy and clinical immunology (01.10.2017)
Published in Journal of allergy and clinical immunology (01.10.2017)
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Journal Article
Expression of clinically relevant drug‐metabolizing enzymes along the human intestine and their correlation to drug transporters and nuclear receptors: An intra‐subject analysis
Fritz, Anja, Busch, Diana, Lapczuk, Joanna, Ostrowski, Marek, Drozdzik, Marek, Oswald, Stefan
Published in Basic & clinical pharmacology & toxicology (01.03.2019)
Published in Basic & clinical pharmacology & toxicology (01.03.2019)
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Journal Article
Landscape of nuclear transport receptor cargo specificity
Mackmull, Marie‐Therese, Klaus, Bernd, Heinze, Ivonne, Chokkalingam, Manopriya, Beyer, Andreas, Russell, Robert B, Ori, Alessandro, Beck, Martin
Published in Molecular systems biology (01.12.2017)
Published in Molecular systems biology (01.12.2017)
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Journal Article
Super-assembly of ER-phagy receptor Atg40 induces local ER remodeling at contacts with forming autophagosomal membranes
Mochida, Keisuke, Yamasaki, Akinori, Matoba, Kazuaki, Kirisako, Hiromi, Noda, Nobuo N., Nakatogawa, Hitoshi
Published in Nature communications (03.07.2020)
Published in Nature communications (03.07.2020)
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Journal Article
Western diet reduces small intestinal intraepithelial lymphocytes via FXR-Interferon pathway
Hung, Chen-Ting, Ma, Changqing, Panda, Santosh K., Trsan, Tihana, Hodel, Miki, Frein, Jennifer, Foster, Amanda, Sun, Shengxiang, Wu, Hung-Ting, Kern, Justin, Mishra, Richa, Jain, Umang, Ho, Ya-Chi, Colonna, Marco, Stappenbeck, Thaddeus S., Liu, Ta-Chiang
Published in Mucosal immunology (01.10.2024)
Published in Mucosal immunology (01.10.2024)
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Journal Article
Functional implications of NHR-210 enrichment in C. elegans cephalic sheath glia: insights into metabolic and mitochondrial disruptions in Parkinson's disease models
Hameed, Rohil, Naseer, Anam, Saxena, Ankit, Akbar, Mahmood, Toppo, Pranoy, Sarkar, Arunabh, Shukla, Sanjeev K., Nazir, Aamir
Published in Cellular and molecular life sciences : CMLS (01.12.2024)
Published in Cellular and molecular life sciences : CMLS (01.12.2024)
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Journal Article
Dynamics of galectin-3 in the nucleus and cytoplasm
Haudek, Kevin C., Spronk, Kimberly J., Voss, Patricia G., Patterson, Ronald J., Wang, John L., Arnoys, Eric J.
Published in Biochimica et biophysica acta (01.02.2010)
Published in Biochimica et biophysica acta (01.02.2010)
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Journal Article
Inactivation of Adenomatous Polyposis Coli Reduces Bile Acid/Farnesoid X Receptor Expression through Fxr gene CpG Methylation in Mouse Colon Tumors and Human Colon Cancer Cells
Selmin, Ornella I, Fang, Changming, Lyon, Adam M, Doetschman, Tom C, Thompson, Patricia A, Martinez, Jesse D, Smith, Jeffrey W, Lance, Peter M, Romagnolo, Donato F
Published in The Journal of nutrition (01.02.2016)
Published in The Journal of nutrition (01.02.2016)
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Journal Article
Human Hepatocytes Support the Hypertrophic but not the Hyperplastic Response to the Murine Nongenotoxic Hepatocarcinogen Sodium Phenobarbital in an In Vivo Study Using a Chimeric Mouse with Humanized Liver
Yamada, Tomoya, Okuda, Yu, Kushida, Masahiko, Sumida, Kayo, Takeuchi, Hayato, Nagahori, Hirohisa, Fukuda, Takako, Lake, Brian G., Cohen, Samuel M., Kawamura, Satoshi
Published in Toxicological sciences (01.11.2014)
Published in Toxicological sciences (01.11.2014)
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Journal Article
Cerebrospinal Fluid Steroidomics: Are Bioactive Bile Acids Present in Brain?
Ogundare, Michael, Theofilopoulos, Spyridon, Lockhart, Andrew, Hall, Leslie J, Arenas, Ernest, Sjövall, Jan, Brenton, A. Gareth, Wang, Yuqin, Griffiths, William J
Published in The Journal of biological chemistry (12.02.2010)
Published in The Journal of biological chemistry (12.02.2010)
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Journal Article
Hepatotoxic effects of (tri)azole fungicides in a broad dose range
Heise, T., Schmidt, F., Knebel, C., Rieke, S., Haider, W., Pfeil, R., Kneuer, C., Niemann, L., Marx-Stoelting, P.
Published in Archives of toxicology (01.11.2015)
Published in Archives of toxicology (01.11.2015)
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Journal Article
Nuclear Receptors and Lipid Physiology: Opening the X-Files
Chawla, Ajay, Repa, Joyce J., Evans, Ronald M., Mangelsdorf, David J.
Published in Science (American Association for the Advancement of Science) (30.11.2001)
Published in Science (American Association for the Advancement of Science) (30.11.2001)
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Journal Article