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The role of ubiquitin-dependent segregase p97 (VCP or Cdc48) in chromatin dynamics after DNA double strand breaks
Torrecilla, Ignacio, Oehler, Judith, Ramadan, Kristijan
Published in Philosophical transactions of the Royal Society of London. Series B. Biological sciences (05.10.2017)
Published in Philosophical transactions of the Royal Society of London. Series B. Biological sciences (05.10.2017)
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Journal Article
The NUCKS1-SKP2-p21/p27 axis controls S phase entry
Hume, Samuel, Grou, Claudia P., Lascaux, Pauline, D’Angiolella, Vincenzo, Legrand, Arnaud J., Ramadan, Kristijan, Dianov, Grigory L.
Published in Nature communications (29.11.2021)
Published in Nature communications (29.11.2021)
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Journal Article
The ubiquitin-dependent ATPase p97 removes cytotoxic trapped PARP1 from chromatin
Krastev, Dragomir B., Li, Shudong, Sun, Yilun, Wicks, Andrew J., Hoslett, Gwendoline, Weekes, Daniel, Badder, Luned M., Knight, Eleanor G., Marlow, Rebecca, Pardo, Mercedes Calvo, Yu, Lu, Talele, Tanaji T., Bartek, Jiri, Choudhary, Jyoti S., Pommier, Yves, Pettitt, Stephen J., Tutt, Andrew N. J., Ramadan, Kristijan, Lord, Christopher J.
Published in Nature cell biology (01.01.2022)
Published in Nature cell biology (01.01.2022)
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Journal Article
TEX264 coordinates p97- and SPRTN-mediated resolution of topoisomerase 1-DNA adducts
Fielden, John, Wiseman, Katherine, Torrecilla, Ignacio, Li, Shudong, Hume, Samuel, Chiang, Shih-Chieh, Ruggiano, Annamaria, Narayan Singh, Abhay, Freire, Raimundo, Hassanieh, Sylvana, Domingo, Enric, Vendrell, Iolanda, Fischer, Roman, Kessler, Benedikt M., Maughan, Timothy S., El-Khamisy, Sherif F., Ramadan, Kristijan
Published in Nature communications (09.03.2020)
Published in Nature communications (09.03.2020)
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Journal Article
Metalloprotease SPRTN/DVC1 Orchestrates Replication-Coupled DNA-Protein Crosslink Repair
Vaz, Bruno, Popovic, Marta, Newman, Joseph A., Fielden, John, Aitkenhead, Hazel, Halder, Swagata, Singh, Abhay Narayan, Vendrell, Iolanda, Fischer, Roman, Torrecilla, Ignacio, Drobnitzky, Neele, Freire, Raimundo, Amor, David J., Lockhart, Paul J., Kessler, Benedikt M., McKenna, Gillies W., Gileadi, Opher, Ramadan, Kristijan
Published in Molecular cell (17.11.2016)
Published in Molecular cell (17.11.2016)
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Journal Article
Targeting TOPK sensitises tumour cells to radiation-induced damage by enhancing replication stress
Herbert, Katharine J., Puliyadi, Rathi, Prevo, Remko, Rodriguez-Berriguete, Gonzalo, Ryan, Anderson, Ramadan, Kristijan, Higgins, Geoff S.
Published in Cell death and differentiation (01.04.2021)
Published in Cell death and differentiation (01.04.2021)
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Journal Article
The protease SPRTN and SUMOylation coordinate DNA-protein crosslink repair to prevent genome instability
Ruggiano, Annamaria, Vaz, Bruno, Kilgas, Susan, Popović, Marta, Rodriguez-Berriguete, Gonzalo, Singh, Abhay N., Higgins, Geoff S., Kiltie, Anne E., Ramadan, Kristijan
Published in Cell reports (Cambridge) (07.12.2021)
Published in Cell reports (Cambridge) (07.12.2021)
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Journal Article
SPRTN protease-cleaved MRE11 decreases DNA repair and radiosensitises cancer cells
Na, Juri, Newman, Joseph A., Then, Chee Kin, Syed, Junetha, Vendrell, Iolanda, Torrecilla, Ignacio, Ellermann, Sophie, Ramadan, Kristijan, Fischer, Roman, Kiltie, Anne E.
Published in Cell death & disease (08.02.2021)
Published in Cell death & disease (08.02.2021)
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Journal Article
Cdc48/p97 promotes reformation of the nucleus by extracting the kinase Aurora B from chromatin
Ramadan, Kristijan, Bruderer, Roland, Spiga, Fabio M., Popp, Oliver, Baur, Tina, Gotta, Monica, Meyer, Hemmo H.
Published in Nature (20.12.2007)
Published in Nature (20.12.2007)
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Journal Article
SPRTN protease and checkpoint kinase 1 cross-activation loop safeguards DNA replication
Halder, Swagata, Torrecilla, Ignacio, Burkhalter, Martin D., Popović, Marta, Fielden, John, Vaz, Bruno, Oehler, Judith, Pilger, Domenic, Lessel, Davor, Wiseman, Katherine, Singh, Abhay Narayan, Vendrell, Iolanda, Fischer, Roman, Philipp, Melanie, Ramadan, Kristijan
Published in Nature communications (17.07.2019)
Published in Nature communications (17.07.2019)
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Journal Article
A three-in-one-bullet for oesophageal cancer: replication fork collapse, spindle attachment failure and enhanced radiosensitivity generated by a ruthenium( ii ) metallo-intercalator
Gill, Martin R., Jarman, Paul J., Halder, Swagata, Walker, Michael G., Saeed, Hiwa K., Thomas, Jim A., Smythe, Carl, Ramadan, Kristijan, Vallis, Katherine A.
Published in Chemical science (Cambridge) (2018)
Published in Chemical science (Cambridge) (2018)
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Journal Article
Chromatin-associated degradation is defined by UBXN-3/FAF1 to safeguard DNA replication fork progression
Franz, André, Pirson, Paul A., Pilger, Domenic, Halder, Swagata, Achuthankutty, Divya, Kashkar, Hamid, Ramadan, Kristijan, Hoppe, Thorsten
Published in Nature communications (04.02.2016)
Published in Nature communications (04.02.2016)
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Journal Article
Erratum: Chromatin-associated degradation is defined by UBXN-3/FAF1 to safeguard DNA replication fork progression
Franz, André, Pirson, Paul A., Pilger, Domenic, Halder, Swagata, Achuthankutty, Divya, Kashkar, Hamid, Ramadan, Kristijan, Hoppe, Thorsten
Published in Nature communications (17.05.2016)
Published in Nature communications (17.05.2016)
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Journal Article
The DNA-polymerase-X family: controllers of DNA quality?
Ramadan, Kristijan, Shevelev, Igor, Hübscher, Ulrich
Published in Nature reviews. Molecular cell biology (01.12.2004)
Published in Nature reviews. Molecular cell biology (01.12.2004)
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Journal Article