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Efficacy and Safety of Evolocumab in Chronic Kidney Disease in the FOURIER Trial
Charytan, David M., Sabatine, Marc S., Pedersen, Terje R., Im, KyungAh, Park, Jeong-Gun, Pineda, Armando Lira, Wasserman, Scott M., Deedwania, Prakash, Olsson, Anders G., Sever, Peter S., Keech, Anthony C., Giugliano, Robert P.
Published in Journal of the American College of Cardiology (18.06.2019)
Published in Journal of the American College of Cardiology (18.06.2019)
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Journal Article
Inclisiran Lowers LDL-C and PCSK9 Irrespective of Diabetes Status: The ORION-1 Randomized Clinical Trial
Leiter, Lawrence A., Teoh, Hwee, Kallend, David, Wright, R. Scott, Landmesser, Ulf, Wijngaard, Peter L.J., Kastelein, John J.P., Ray, Kausik K.
Published in Diabetes care (01.01.2019)
Published in Diabetes care (01.01.2019)
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Journal Article
PCSK9 Association With Lipoprotein(a)
Tavori, Hagai, Christian, Devon, Minnier, Jessica, Plubell, Deanna, Shapiro, Michael D., Yeang, Calvin, Giunzioni, Ilaria, Croyal, Mikael, Duell, P. Barton, Lambert, Gilles, Tsimikas, Sotirios, Fazio, Sergio
Published in Circulation research (24.06.2016)
Published in Circulation research (24.06.2016)
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Journal Article
Association of PCSK9 with platelet reactivity in patients with acute coronary syndrome treated with prasugrel or ticagrelor: The PCSK9-REACT study
Navarese, Eliano P., Kolodziejczak, Michalina, Winter, Max-Paul, Alimohammadi, Arman, Lang, Irene M., Buffon, Antonino, Lip, Gregory YH, Siller-Matula, Jolanta M.
Published in International journal of cardiology (15.01.2017)
Published in International journal of cardiology (15.01.2017)
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Journal Article
Hepatic Sensing Loop Regulates PCSK9 Secretion in Response to Inhibitory Antibodies
Oleaga, Carlota, Shapiro, Michael D., Hay, Joshua, Mueller, Paul A., Miles, Joshua, Huang, Cecilia, Friz, Emily, Tavori, Hagai, Toth, Peter P., Wójcik, Cezary, Warden, Bruce A., Purnell, Jonathan Q., Duell, P. Barton, Pamir, Nathalie, Fazio, Sergio
Published in Journal of the American College of Cardiology (05.10.2021)
Published in Journal of the American College of Cardiology (05.10.2021)
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Journal Article
PCSK9 Activity Is Potentiated Through HDL Binding
Burnap, Sean A., Sattler, Katherine, Pechlaner, Raimund, Duregotti, Elisa, Lu, Ruifang, Theofilatos, Konstantinos, Takov, Kaloyan, Heusch, Gerd, Tsimikas, Sotirios, Fernández-Hernando, Carlos, Berry, Sarah E., Hall, Wendy L., Notdurfter, Marlene, Rungger, Gregorio, Paulweber, Bernhard, Willeit, Johann, Kiechl, Stefan, Levkau, Bodo, Mayr, Manuel
Published in Circulation research (12.11.2021)
Published in Circulation research (12.11.2021)
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Journal Article
Enhanced identification of familial hypercholesterolemia using central laboratory algorithms
Ibrahim, Shirin, Nurmohamed, Nick S., Nierman, Melchior C., de Goeij, Jim N., Zuurbier, Linda, van Rooij, Jeroen, Schonck, Willemijn A.M., de Vries, Jard, Hovingh, G. Kees, Reeskamp, Laurens F., Stroes, Erik S.G.
Published in Atherosclerosis (01.06.2024)
Published in Atherosclerosis (01.06.2024)
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Journal Article
Prediction of cardiovascular events with levels of proprotein convertase subtilisin/kexin type 9: A systematic review and meta-analysis
Vlachopoulos, Charalambos, Terentes-Printzios, Dimitrios, Georgiopoulos, Georgios, Skoumas, Ioannis, Koutagiar, Iosif, Ioakeimidis, Nikolaos, Stefanadis, Christodoulos, Tousoulis, Dimitrios
Published in Atherosclerosis (01.09.2016)
Published in Atherosclerosis (01.09.2016)
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Journal Article
Thyroid stimulating hormone exhibits the impact on LDLR/LDL-c via up-regulating hepatic PCSK9 expression
Gong, Yingyun, Ma, Yizhe, Ye, Zhengqin, Fu, Zhenzhen, Yang, Panpan, Gao, Beibei, Guo, Wen, Hu, Dandan, Ye, Jingya, Ma, Shuai, Zhang, Fan, Zhou, Li, Xu, Xinyu, Li, Zhong, Yang, Tao, Zhou, Hongwen
Published in Metabolism, clinical and experimental (01.11.2017)
Published in Metabolism, clinical and experimental (01.11.2017)
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Journal Article
Obesity and type 2 diabetes are associated with elevated PCSK9 levels in young women
Levenson, Amy E., Shah, Amy S., Khoury, Philip R., Kimball, Thomas R., Urbina, Elaine M., de Ferranti, Sarah D., Maahs, David M., Dolan, Lawrence M., Wadwa, R. Paul, Biddinger, Sudha B.
Published in Pediatric diabetes (01.12.2017)
Published in Pediatric diabetes (01.12.2017)
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Journal Article
Circulating PCSK9 levels are not associated with the conversion to type 2 diabetes
Ramin-Mangata, Stéphane, Wargny, Matthieu, Pichelin, Matthieu, Le May, Cédric, Thédrez, Aurélie, Blanchard, Valentin, Nativel, Brice, Santos, Raul D., Benseñor, Isabela M., Lotufo, Paulo A., Lambert, Gilles, Cariou, Bertrand
Published in Atherosclerosis (01.01.2020)
Published in Atherosclerosis (01.01.2020)
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Journal Article
The interplay of LDLR, PCSK9, and lncRNA- LASER genes expression in coronary artery disease: Implications for therapeutic interventions
Ghiasvand, Tayebe, Karimi, Jamshid, Khodadadi, Iraj, Yazdi, Amirhossein, Khazaei, Salman, kichi, Zahra Abedi, Hosseini, Seyed Kianoosh
Published in Prostaglandins & other lipid mediators (01.03.2025)
Published in Prostaglandins & other lipid mediators (01.03.2025)
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Journal Article
Treatment with the natural FXR agonist chenodeoxycholic acid reduces clearance of plasma LDL whilst decreasing circulating PCSK9, lipoprotein(a) and apolipoprotein C‐III
Ghosh Laskar, M., Eriksson, M., Rudling, M., Angelin, B.
Published in Journal of internal medicine (01.06.2017)
Published in Journal of internal medicine (01.06.2017)
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Journal Article
Coronary Endothelial Dysfunction Is Associated With Elevated Serum PCSK9 Levels in People With HIV Independent of Low‐Density Lipoprotein Cholesterol
Leucker, Thorsten M., Weiss, Robert G., Schär, Michael, Bonanno, Gabriele, Mathews, Lena, Jones, Steven R., Brown, Todd T., Moore, Richard, Afework, Yohannes, Gerstenblith, Gary, Hays, Allison G.
Published in Journal of the American Heart Association (02.10.2018)
Published in Journal of the American Heart Association (02.10.2018)
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Journal Article
High circulating proprotein convertase subtilisin/Kexin type 9 concentration associates with cardiovascular risk: A meta-analysis of cohort studies
Qiu, Chengfeng, Zhou, Quan, Li, Xiaohui, Zhang, Zhen, Zeng, Pingyu, Cao, Zeng, Pan, Bingjie, Li, Xiaogang, Chen, Alex F.
Published in Medicine (Baltimore) (01.12.2017)
Published in Medicine (Baltimore) (01.12.2017)
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Journal Article
Evaluation of Evolocumab (AMG 145), a Fully Human Anti‐PCSK9 IgG2 Monoclonal Antibody, in Subjects With Hepatic Impairment
Gibbs, John P., Slatter, J. Greg, Egbuna, Ogo, Geller, Michelle, Hamilton, Lisa, Dias, Clapton S., Xu, Ren Y., Johnson, Jessica, Wasserman, Scott M., Emery, Maurice G.
Published in Journal of clinical pharmacology (01.04.2017)
Published in Journal of clinical pharmacology (01.04.2017)
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Journal Article
Plasma Proprotein Convertase Subtilisin Kexin Type 9 as a Predictor of Carotid Atherosclerosis in Asymptomatic Adults
Chan, Dick C., Pang, Jing, McQuillan, B.M., Hung, Joseph, Beilby, John P., Barrett, P. Hugh R., Watts, Gerald F.
Published in Heart, lung & circulation (01.05.2016)
Published in Heart, lung & circulation (01.05.2016)
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Journal Article