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Highly potent HIV-specific antibody neutralization in vitro translates into effective protection against mucosal SHIV challenge in vivo
Moldt, Brian, Rakasz, Eva G, Schultz, Niccole, Chan-Hui, Po-Ying, Swiderek, Kristine, Weisgrau, Kimberly L, Piaskowski, Shari M, Bergman, Zachary, Watkins, David I, Poignard, Pascal, Burton, Dennis R
Published in Proceedings of the National Academy of Sciences - PNAS (13.11.2012)
Published in Proceedings of the National Academy of Sciences - PNAS (13.11.2012)
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Journal Article
Passive transfer of modest titers of potent and broadly neutralizing anti-HIV monoclonal antibodies block SHIV infection in macaques
Shingai, Masashi, Donau, Olivia K., Plishka, Ronald J., Buckler-White, Alicia, Mascola, John R., Nabel, Gary J., Nason, Martha C., Montefiori, David, Moldt, Brian, Poignard, Pascal, Diskin, Ron, Bjorkman, Pamela J., Eckhaus, Michael A., Klein, Florian, Mouquet, Hugo, Cetrulo Lorenzi, Julio Cesar, Gazumyan, Anna, Burton, Dennis R., Nussenzweig, Michel C., Martin, Malcolm A., Nishimura, Yoshiaki
Published in The Journal of experimental medicine (22.09.2014)
Published in The Journal of experimental medicine (22.09.2014)
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Journal Article
Broad neutralization coverage of HIV by multiple highly potent antibodies
Walker, Laura M., Huber, Michael, Doores, Katie J., Falkowska, Emilia, Pejchal, Robert, Julien, Jean-Philippe, Wang, Sheng-Kai, Ramos, Alejandra, Chan-Hui, Po-Ying, Moyle, Matthew, Mitcham, Jennifer L., Hammond, Phillip W., Olsen, Ole A., Phung, Pham, Fling, Steven, Wong, Chi-Huey, Phogat, Sanjay, Wrin, Terri, Simek, Melissa D., Principal Investigators, Protocol G., Koff, Wayne C., Wilson, Ian A., Burton, Dennis R., Poignard, Pascal
Published in Nature (London) (22.09.2011)
Published in Nature (London) (22.09.2011)
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Journal Article
Broad and Potent Neutralizing Antibodies from an African Donor Reveal a New HIV-1 Vaccine Target
Walker, Laura M, Phogat, Sanjay K, Chan-Hui, Po-Ying, Wagner, Denise, Phung, Pham, Goss, Julie L, Wrin, Terri, Simek, Melissa D, Fling, Steven, Mitcham, Jennifer L, Lehrman, Jennifer K, Priddy, Frances H, Olsen, Ole A, Frey, Steven M, Hammond, Phillip W, Kaminsky, Stephen, Zamb, Timothy, Moyle, Matthew, Koff, Wayne C, Poignard, Pascal, Burton, Dennis R
Published in Science (American Association for the Advancement of Science) (09.10.2009)
Published in Science (American Association for the Advancement of Science) (09.10.2009)
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Journal Article
Effective, low-titer antibody protection against low-dose repeated mucosal SHIV challenge in macaques
Hessell, Ann J, Poignard, Pascal, Hunter, Meredith, Hangartner, Lars, Tehrani, David M, Bleeker, Wim K, Parren, Paul W H I, Marx, Preston A, Burton, Dennis R
Published in Nature medicine (01.08.2009)
Published in Nature medicine (01.08.2009)
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Journal Article
SARS-CoV-2 Variants in Immunocompromised Patient Given Antibody Monotherapy
Truffot, Aurélie, Andréani, Julien, Le Maréchal, Marion, Caporossi, Alban, Epaulard, Olivier, Germi, Raphaele, Poignard, Pascal, Larrat, Sylvie
Published in Emerging infectious diseases (01.10.2021)
Published in Emerging infectious diseases (01.10.2021)
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Journal Article
Target-agnostic identification of human antibodies to Plasmodium falciparum sexual forms reveals cross-stage recognition of glutamate-rich repeats
Amen, Axelle, Yoo, Randy, Fabra-García, Amanda, Bolscher, Judith, Stone, William JR, Bally, Isabelle, Dergan-Dylon, Sebastián, Kucharska, Iga, de Jong, Roos M, de Bruijni, Marloes, Bousema, Teun, King, C Richter, MacGill, Randall S, Sauerwein, Robert W, Julien, Jean-Philippe, Poignard, Pascal, Jore, Matthijs M
Published in eLife (16.01.2025)
Published in eLife (16.01.2025)
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Journal Article
Limited or no protection by weakly or nonneutralizing antibodies against vaginal SHIV challenge of macaques compared with a strongly neutralizing antibody
Burton, Dennis R, Hessell, Ann J, Keele, Brandon F, Klasse, Per Johan, Ketas, Thomas A, Moldt, Brian, Dunlop, D. Cameron, Poignard, Pascal, Doyle, Lara A, Cavacini, Lisa, Veazey, Ronald S, Moore, John P
Published in Proceedings of the National Academy of Sciences - PNAS (05.07.2011)
Published in Proceedings of the National Academy of Sciences - PNAS (05.07.2011)
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Journal Article
Single-Virus Droplet Microfluidics for High-Throughput Screening of Neutralizing Epitopes on HIV Particles
Chaipan, Chawaree, Pryszlak, Anna, Dean, Hansi, Poignard, Pascal, Benes, Vladimir, Griffiths, Andrew D., Merten, Christoph A.
Published in Cell chemical biology (22.06.2017)
Published in Cell chemical biology (22.06.2017)
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Journal Article
A Limited Number of Antibody Specificities Mediate Broad and Potent Serum Neutralization in Selected HIV-1 Infected Individuals
Walker, Laura M., Simek, Melissa D., Priddy, Frances, Gach, Johannes S., Wagner, Denise, Zwick, Michael B., Phogat, Sanjay K., Poignard, Pascal, Burton, Dennis R.
Published in PLoS pathogens (01.08.2010)
Published in PLoS pathogens (01.08.2010)
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Journal Article
Human Immunodeficiency Virus Type 1 Elite Neutralizers: Individuals with Broad and Potent Neutralizing Activity Identified by Using a High-Throughput Neutralization Assay together with an Analytical Selection Algorithm
Simek, Melissa D., Rida, Wasima, Priddy, Frances H., Pung, Pham, Carrow, Emily, Laufer, Dagna S., Lehrman, Jennifer K., Boaz, Mark, Tarragona-Fiol, Tony, Miiro, George, Birungi, Josephine, Pozniak, Anton, McPhee, Dale A., Manigart, Olivier, Karita, Etienne, Inwoley, André, Jaoko, Walter, DeHovitz, Jack, Bekker, Linda-Gail, Pitisuttithum, Punnee, Paris, Robert, Walker, Laura M., Poignard, Pascal, Wrin, Terri, Fast, Patricia E., Burton, Dennis R., Koff, Wayne C.
Published in Journal of Virology (15.07.2009)
Published in Journal of Virology (15.07.2009)
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Journal Article
Broadly Neutralizing Human Anti-HIV Antibody 2G12 Is Effective in Protection against Mucosal SHIV Challenge Even at Low Serum Neutralizing Titers
Hessell, Ann J., Rakasz, Eva G., Poignard, Pascal, Hangartner, Lars, Landucci, Gary, Forthal, Donald N., Koff, Wayne C., Watkins, David I., Burton, Dennis R.
Published in PLoS pathogens (01.05.2009)
Published in PLoS pathogens (01.05.2009)
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Journal Article
Broadly Neutralizing Monoclonal Antibodies 2F5 and 4E10 Directed against the Human Immunodeficiency Virus Type 1 gp41 Membrane-Proximal External Region Protect against Mucosal Challenge by Simian-Human Immunodeficiency Virus SHIVBa-L
HESSELL, Ann J, RAKASZ, Eva G, BURTON, Dennis R, TEHRANI, David M, HUBER, Michael, WEISGRAU, Kimberly L, LANDUCCI, Gary, FORTHAL, Donald N, KOFF, Wayne C, POIGNARD, Pascal, WATKINS, David I
Published in Journal of Virology (01.02.2010)
Published in Journal of Virology (01.02.2010)
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Journal Article
Toward a more accurate view of human B-cell repertoire by next-generation sequencing, unbiased repertoire capture and single-molecule barcoding
He, Linling, Sok, Devin, Azadnia, Parisa, Hsueh, Jessica, Landais, Elise, Simek, Melissa, Koff, Wayne C., Poignard, Pascal, Burton, Dennis R., Zhu, Jiang
Published in Scientific reports (27.10.2014)
Published in Scientific reports (27.10.2014)
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Journal Article
Broad neutralization by a combination of antibodies recognizing the CD4 binding site and a new conformational epitope on the HIV-1 envelope protein
Klein, Florian, Gaebler, Christian, Mouquet, Hugo, Sather, D. Noah, Lehmann, Clara, Scheid, Johannes F., Kraft, Zane, Liu, Yan, Pietzsch, John, Hurley, Arlene, Poignard, Pascal, Feizi, Ten, Morris, Lynn, Walker, Bruce D., Fätkenheuer, Gerd, Seaman, Michael S., Stamatatos, Leonidas, Nussenzweig, Michel C.
Published in The Journal of experimental medicine (30.07.2012)
Published in The Journal of experimental medicine (30.07.2012)
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Journal Article
Structure and function of broadly reactive antibody PG16 reveal an H3 subdomain that mediates potent neutralization of HIV-1
Pejchal, Robert, Walker, Laura M., Stanfield, Robyn L., Phogat, Sanjay K., Koff, Wayne C., Poignard, Pascal, Burton, Dennis R., Wilson, Ian A., Baker, David
Published in Proceedings of the National Academy of Sciences - PNAS (22.06.2010)
Published in Proceedings of the National Academy of Sciences - PNAS (22.06.2010)
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Journal Article
Co-evolution of HIV Envelope and Apex-Targeting Neutralizing Antibody Lineage Provides Benchmarks for Vaccine Design
Rantalainen, Kimmo, Berndsen, Zachary T., Murrell, Sasha, Cao, Liwei, Omorodion, Oluwarotimi, Torres, Jonathan L., Wu, Mengyu, Umotoy, Jeffrey, Copps, Jeffrey, Poignard, Pascal, Landais, Elise, Paulson, James C., Wilson, Ian A., Ward, Andrew B.
Published in Cell reports (Cambridge) (12.06.2018)
Published in Cell reports (Cambridge) (12.06.2018)
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Journal Article
Complement Alternative and Mannose-Binding Lectin Pathway Activation Is Associated With COVID-19 Mortality
Defendi, Federica, Leroy, Corentin, Epaulard, Olivier, Clavarino, Giovanna, Vilotitch, Antoine, Le Marechal, Marion, Jacob, Marie-Christine, Raskovalova, Tatiana, Pernollet, Martine, Le Gouellec, Audrey, Bosson, Jean-Luc, Poignard, Pascal, Roustit, Matthieu, Thielens, Nicole, Dumestre-Pérard, Chantal, Cesbron, Jean-Yves
Published in Frontiers in immunology (10.09.2021)
Published in Frontiers in immunology (10.09.2021)
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Journal Article
Incomplete Neutralization and Deviation from Sigmoidal Neutralization Curves for HIV Broadly Neutralizing Monoclonal Antibodies
McCoy, Laura E., Falkowska, Emilia, Doores, Katie J., Le, Khoa, Sok, Devin, van Gils, Marit J., Euler, Zelda, Burger, Judith A., Seaman, Michael S., Sanders, Rogier W., Schuitemaker, Hanneke, Poignard, Pascal, Wrin, Terri, Burton, Dennis R.
Published in PLoS pathogens (01.08.2015)
Published in PLoS pathogens (01.08.2015)
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