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MuSK IgG4 autoantibodies cause myasthenia gravis by inhibiting binding between MuSK and Lrp4
Huijbers, Maartje G., Zhang, Wei, Klooster, Rinse, Niks, Erik H., Friese, Matthew B., Straasheijm, Kirsten R., Thijssen, Peter E., Vrolijk, Hans, Plomp, Jaap J., Vogels, Pauline, Losen, Mario, Van der Maarel, Silvère M., Burden, Steven J., Verschuuren, Jan J.
Published in Proceedings of the National Academy of Sciences - PNAS (17.12.2013)
Published in Proceedings of the National Academy of Sciences - PNAS (17.12.2013)
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Journal Article
Optogenetic termination of ventricular arrhythmias in the whole heart: towards biological cardiac rhythm management
Nyns, Emile C.A., Kip, Annemarie, Bart, Cindy I., Plomp, Jaap J., Zeppenfeld, Katja, Schalij, Martin J., de Vries, Antoine A.F., Pijnappels, Daniël A.
Published in European heart journal (14.07.2017)
Published in European heart journal (14.07.2017)
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Journal Article
Functional monovalency amplifies the pathogenicity of anti-MuSK IgG4 in myasthenia gravis
Vergoossen, Dana L. E., Plomp, Jaap J., Gstöttner, Christoph, Fillié-Grijpma, Yvonne E., Augustinus, Roy, Verpalen, Robyn, Wuhrer, Manfred, Parren, Paul W. H. I., Dominguez-Vega, Elena, van der Maarel, Silvère M., Verschuuren, Jan J., Huijbers, Maartje G.
Published in Proceedings of the National Academy of Sciences - PNAS (30.03.2021)
Published in Proceedings of the National Academy of Sciences - PNAS (30.03.2021)
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Journal Article
Muscle-specific kinase myasthenia gravis IgG4 autoantibodies cause severe neuromuscular junction dysfunction in mice
Klooster, Rinse, Plomp, Jaap J., Huijbers, Maartje G., Niks, Erik H., Straasheijm, Kirsten R., Detmers, Frank J., Hermans, Pim W., Sleijpen, Kevin, Verrips, Aad, Losen, Mario, Martinez-Martinez, Pilar, De Baets, Marc H., van der Maarel, Silvère M., Verschuuren, Jan J.
Published in Brain (London, England : 1878) (01.04.2012)
Published in Brain (London, England : 1878) (01.04.2012)
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Journal Article
Characterization of neuromuscular synapse function abnormalities in multiple Duchenne muscular dystrophy mouse models
van der Pijl, Elizabeth M., van Putten, Maaike, Niks, Erik H., Verschuuren, Jan J. G. M., Aartsma-Rus, Annemieke, Plomp, Jaap J.
Published in The European journal of neuroscience (01.06.2016)
Published in The European journal of neuroscience (01.06.2016)
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Journal Article
Development and characterization of agonistic antibodies targeting the Ig-like 1 domain of MuSK
Lim, Jamie L., Augustinus, Roy, Plomp, Jaap J., Roya-Kouchaki, Kasra, Vergoossen, Dana L. E., Fillié-Grijpma, Yvonne, Struijk, Josephine, Thomas, Rachel, Salvatori, Daniela, Steyaert, Christophe, Blanchetot, Christophe, Vanhauwaert, Roeland, Silence, Karen, van der Maarel, Silvère M., Verschuuren, Jan J., Huijbers, Maartje G.
Published in Scientific reports (08.05.2023)
Published in Scientific reports (08.05.2023)
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Journal Article
Cross-sectional study into age-related pathology of mouse models for limb girdle muscular dystrophy types 2D and 2F
Verhaart, Ingrid E. C., Putker, Kayleigh, van de Vijver, Davy, Tanganyika-de Winter, Christa L., Pasteuning-Vuhman, Svetlana, Plomp, Jaap J., Aartsma-Rus, Annemieke M., van Putten, Maaike
Published in PloS one (20.08.2019)
Published in PloS one (20.08.2019)
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Journal Article
High cortical spreading depression susceptibility and migraine-associated symptoms in Cav2.1 S218L mice
van den Maagdenberg, Arn M. J. M., Pizzorusso, Tommaso, Kaja, Simon, Terpolilli, Nicole, Shapovalova, Maryna, Hoebeek, Freek E., Barrett, Curtis F., Gherardini, Lisa, van de Ven, Rob C. G., Todorov, Boyan, Broos, Ludo A. M., Tottene, Angelita, Gao, Zhenyu, Fodor, Mariann, De Zeeuw, Chris I., Frants, Rune R., Plesnila, Nikolaus, Plomp, Jaap J., Pietrobon, Daniela, Ferrari, Michel D.
Published in Annals of neurology (01.01.2010)
Published in Annals of neurology (01.01.2010)
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Journal Article
Neuromuscular synapse electrophysiology in myasthenia gravis animal models
Plomp, Jaap J., Huijbers, Maartje G.M., Verschuuren, Jan J.G.M.
Published in Annals of the New York Academy of Sciences (01.01.2018)
Published in Annals of the New York Academy of Sciences (01.01.2018)
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Journal Article
Pathogenic IgG4 subclass autoantibodies in MuSK myasthenia gravis
Plomp, Jaap J., Huijbers, Maartje G., van der Maarel, Silvère M., Verschuuren, Jan J.
Published in Annals of the New York Academy of Sciences (01.12.2012)
Published in Annals of the New York Academy of Sciences (01.12.2012)
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Journal Article
Acute and chronic effects of treatment with mesenchymal stromal cells on LPS-induced pulmonary inflammation, emphysema and atherosclerosis development
Khedoe, P. Padmini S. J., de Kleijn, Stan, van Oeveren-Rietdijk, Annemarie M., Plomp, Jaap J., de Boer, Hetty C., van Pel, Melissa, Rensen, Patrick C. N., Berbée, Jimmy F. P., Hiemstra, Pieter S.
Published in PloS one (14.09.2017)
Published in PloS one (14.09.2017)
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Journal Article
The neuropathic potential of anti-GM1 autoantibodies is regulated by the local glycolipid environment in mice
Greenshields, Kay N., Halstead, Susan K., Zitman, Femke M.P., Rinaldi, Simon, Brennan, Kathryn M., O’Leary, Colin, Chamberlain, Luke H., Easton, Alistair, Roxburgh, Jennifer, Pediani, John, Furukawa, Koichi, Furukawa, Keiko, Goodyear, Carl S., Plomp, Jaap J., Willison, Hugh J.
Published in The Journal of clinical investigation (01.03.2009)
Published in The Journal of clinical investigation (01.03.2009)
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Journal Article
Munc18-1 Expression Levels Control Synapse Recovery by Regulating Readily Releasable Pool Size
Toonen, Ruud F. G., Wierda, Keimpe, Sons, Michèle S., de Wit, Heidi, Cornelisse, L. Niels, Brussaard, Arjen, Plomp, Jaap J., Verhage, Matthijs
Published in Proceedings of the National Academy of Sciences - PNAS (28.11.2006)
Published in Proceedings of the National Academy of Sciences - PNAS (28.11.2006)
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Journal Article
Comparison of skeletal muscle pathology and motor function of dystrophin and utrophin deficient mouse strains
van Putten, Maaike, Kumar, Darshan, Hulsker, Margriet, Hoogaars, Willem M.H., Plomp, Jaap J., van Opstal, Annemarieke, van Iterson, Maarten, Admiraal, Peter, van Ommen, Gert-Jan B., ‘t Hoen, Peter A.C., Aartsma-Rus, Annemieke
Published in Neuromuscular disorders : NMD (01.05.2012)
Published in Neuromuscular disorders : NMD (01.05.2012)
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Journal Article
Patient-specific therapeutic benefit of MuSK agonist antibody ARGX-119 in MuSK myasthenia gravis passive transfer models
Lim, Jamie L., Jensen, Stine Marie, Plomp, Jaap J., Vankerckhoven, Bernhardt, Kneip, Christa, Coppejans, Rani, Steyaert, Christophe, Moens, Kathleen, De Clercq, Lieselot, Tannemaat, Martijn R., Ulrichts, Peter, Silence, Karen, van der Maarel, Silvère M., Vergoossen, Dana L.E., Vanhauwaert, Roeland, Verschuuren, Jan J., Huijbers, Maartje G.
Published in iScience (21.02.2025)
Published in iScience (21.02.2025)
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Journal Article
Synaptic Assembly of the Brain in the Absence of Neurotransmitter Secretion
Verhage, Matthijs, Maia, Ascanio S., Plomp, Jaap J., Brussaard, Arjen B., Heeroma, Joost H., Vermeer, Hendrika, Toonen, Ruud F., Hammer, Robert E., van den Berg, Timo K., Missler, Markus, Geuze, Hans J., Südhof, Thomas C.
Published in Science (American Association for the Advancement of Science) (04.02.2000)
Published in Science (American Association for the Advancement of Science) (04.02.2000)
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Journal Article