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A deep learning genome-mining strategy for biosynthetic gene cluster prediction
Hannigan, Geoffrey D, Prihoda, David, Palicka, Andrej, Soukup, Jindrich, Klempir, Ondrej, Rampula, Lena, Durcak, Jindrich, Wurst, Michael, Kotowski, Jakub, Chang, Dan, Wang, Rurun, Piizzi, Grazia, Temesi, Gergely, Hazuda, Daria J, Woelk, Christopher H, Bitton, Danny A
Published in Nucleic acids research (10.10.2019)
Published in Nucleic acids research (10.10.2019)
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Journal Article
Detection of cell–cell interactions via photocatalytic cell tagging
Oslund, Rob C., Reyes-Robles, Tamara, White, Cory H., Tomlinson, Jake H., Crotty, Kelly A., Bowman, Edward P., Chang, Dan, Peterson, Vanessa M., Li, Lixia, Frutos, Silvia, Vila-Perelló, Miquel, Vlerick, David, Cromie, Karen, Perlman, David H., Ingale, Sampat, Hara, Samantha D. O’, Roberts, Lee R., Piizzi, Grazia, Hett, Erik C., Hazuda, Daria J., Fadeyi, Olugbeminiyi O.
Published in Nature chemical biology (01.08.2022)
Published in Nature chemical biology (01.08.2022)
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Journal Article
Characterization of Autoinducer‑3 Structure and Biosynthesis in E. coli
Kim, Chung Sub, Gatsios, Alexandra, Cuesta, Santiago, Lam, Yick Chong, Wei, Zheng, Chen, Haiwei, Russell, Regan M, Shine, Emilee E, Wang, Rurun, Wyche, Thomas P, Piizzi, Grazia, Flavell, Richard A, Palm, Noah W, Sperandio, Vanessa, Crawford, Jason M
Published in ACS central science (26.02.2020)
Published in ACS central science (26.02.2020)
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Journal Article
Sulfamethoxazole drug stress upregulates antioxidant immunomodulatory metabolites in Escherichia coli
Park, Hyun Bong, Wei, Zheng, Oh, Joonseok, Xu, Hao, Kim, Chung Sub, Wang, Rurun, Wyche, Thomas P., Piizzi, Grazia, Flavell, Richard A., Crawford, Jason M.
Published in Nature microbiology (01.11.2020)
Published in Nature microbiology (01.11.2020)
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Journal Article
Nicotinamide Phosphoribosyltransferase Inhibitor as a Novel Payload for Antibody–Drug Conjugates
Karpov, Alexei S, Abrams, Tinya, Clark, Suzanna, Raikar, Ankita, D’Alessio, Joseph A, Dillon, Michael P, Gesner, Thomas G, Jones, Darryl, Lacaud, Marion, Mallet, William, Martyniuk, Piotr, Meredith, Erik, Mohseni, Morvarid, Nieto-Oberhuber, Cristina M, Palacios, Daniel, Perruccio, Francesca, Piizzi, Grazia, Zurini, Mauro, Bialucha, Carl Uli
Published in ACS medicinal chemistry letters (09.08.2018)
Published in ACS medicinal chemistry letters (09.08.2018)
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Journal Article
Enantioselective Total Synthesis of (−)-Acylfulvene and (−)-Irofulven
Siegel, Dustin S, Piizzi, Grazia, Piersanti, Giovanni, Movassaghi, Mohammad
Published in Journal of organic chemistry (18.12.2009)
Published in Journal of organic chemistry (18.12.2009)
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Journal Article
Enantioselective Total Synthesis of (−)-Acylfulvene and (−)-Irofulven
Movassaghi, Mohammad, Piizzi, Grazia, Siegel, Dustin S., Piersanti, Giovanni
Published in Angewandte Chemie International Edition (04.09.2006)
Published in Angewandte Chemie International Edition (04.09.2006)
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Journal Article
High-Throughput Screen for Inhibitors of Klebsiella pneumoniae Virulence Using a Tetrahymena pyriformis Co-Culture Surrogate Host Model
Woods, Angela L, Parker, David, Glick, Meir M, Peng, Yunshan, Lenoir, Francois, Mulligan, Evan, Yu, Vincent, Piizzi, Grazia, Lister, Troy, Lilly, Maria-Dawn, Dzink-Fox, JoAnn, Jansen, Johanna M, Ryder, Neil S, Dean, Charles R, Smith, Thomas M
Published in ACS omega (15.02.2022)
Published in ACS omega (15.02.2022)
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Journal Article
Cellular Stress Upregulates Indole Signaling Metabolites in Escherichia coli
Kim, Chung Sub, Li, Jhe-Hao, Barco, Brenden, Park, Hyun Bong, Gatsios, Alexandra, Damania, Ashiti, Wang, Rurun, Wyche, Thomas P., Piizzi, Grazia, Clay, Nicole K., Crawford, Jason M.
Published in Cell chemical biology (18.06.2020)
Published in Cell chemical biology (18.06.2020)
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Journal Article
N‐Acyl Amides from Neisseria meningitidis and Their Role in Sphingosine Receptor Signaling
Cho, Wooyoung, York, Autumn G., Wang, Rurun, Wyche, Thomas P., Piizzi, Grazia, Flavell, Richard A., Crawford, Jason M.
Published in Chembiochem : a European journal of chemical biology (18.11.2022)
Published in Chembiochem : a European journal of chemical biology (18.11.2022)
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Journal Article
Bacterial Autoimmune Drug Metabolism Transforms an Immunomodulator into Structurally and Functionally Divergent Antibiotics
Park, Hyun Bong, Goddard, Tyler N., Oh, Joonseok, Patel, Jaymin, Wei, Zheng, Perez, Corey E., Mercado, Brandon Q., Wang, Rurun, Wyche, Thomas P., Piizzi, Grazia, Flavell, Richard A., Crawford, Jason M.
Published in Angewandte Chemie International Edition (11.05.2020)
Published in Angewandte Chemie International Edition (11.05.2020)
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Journal Article
Cellular stress upregulates indole signaling metabolites in E. coli
Kim, Chung Sub, Li, Jhe-Hao, Barco, Brenden, Park, Hyun Bong, Gatsios, Alexandra, Damania, Ashiti, Wang, Rurun, Wyche, Thomas P., Piizzi, Grazia, Clay, Nicole K., Crawford, Jason M.
Published in Cell chemical biology (02.04.2020)
Published in Cell chemical biology (02.04.2020)
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Journal Article
Design, Synthesis, and Properties of a Potent Inhibitor of Pseudomonas aeruginosa Deacetylase LpxC
Piizzi, Grazia, Parker, David T, Peng, Yunshan, Dobler, Markus, Patnaik, Anup, Wattanasin, Som, Liu, Eugene, Lenoir, Francois, Nunez, Jill, Kerrigan, John, McKenney, David, Osborne, Colin, Yu, Donghui, Lanieri, Leanne, Bojkovic, Jade, Dzink-Fox, JoAnn, Lilly, Maria-Dawn, Sprague, Elizabeth R, Lu, Yipin, Wang, Hongming, Ranjitkar, Srijan, Xie, Lili, Wang, Bing, Glick, Meir, Hamann, Lawrence G, Tommasi, Ruben, Yang, Xia, Dean, Charles R
Published in Journal of medicinal chemistry (22.06.2017)
Published in Journal of medicinal chemistry (22.06.2017)
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Journal Article
Discovery of a Brain-Penetrant ATP-Competitive Inhibitor of the Mechanistic Target of Rapamycin (mTOR) for CNS Disorders
Bonazzi, Simone, Goold, Carleton P, Gray, Audrey, Thomsen, Noel M, Nunez, Jill, Karki, Rajeshri G, Gorde, Aakruti, Biag, Jonathan D, Malik, Hasnain A, Sun, Yingchuan, Liang, Guiqing, Lubicka, Danuta, Salas, Sarah, Labbe-Giguere, Nancy, Keaney, Erin P, McTighe, Stephanie, Liu, Shanming, Deng, Lin, Piizzi, Grazia, Lombardo, Franco, Burdette, Doug, Dodart, Jean-Cosme, Wilson, Christopher J, Peukert, Stefan, Curtis, Daniel, Hamann, Lawrence G, Murphy, Leon O
Published in Journal of medicinal chemistry (13.02.2020)
Published in Journal of medicinal chemistry (13.02.2020)
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Journal Article
Identification of Brain-Penetrant ATP-Competitive mTOR Inhibitors for CNS Syndromes
Bonazzi, Simone, Gray, Audrey, Thomsen, Noel M., Biag, Jonathan, Labbe-Giguere, Nancy, Keaney, Erin P., Malik, Hasnain A., Sun, Yingchuan, Nunez, Jill, Karki, Rajeshri G., Knapp, Mark, Elling, Robert, Fuller, John, Pardee, Gwynn, Craig, Lucas, Capre, Ketthsy, Salas, Sarah, Gorde, Aakruti, Liang, Guiqing, Lubicka, Danuta, McTighe, Stephanie M., Goold, Carleton, Liu, Shanming, Deng, Lin, Hong, Jin, Fekete, Alexander, Stadelmann, Pascal, Frieauff, Wilfried, Elhajouji, Azeddine, Bauer, Daniel, Lerchner, Andreas, Radetich, Branko, Furet, Pascal, Piizzi, Grazia, Burdette, Doug, Wilson, Christopher J., Peukert, Stefan, Hamann, Lawrence G., Murphy, Leon O., Curtis, Daniel
Published in Journal of medicinal chemistry (13.07.2023)
Published in Journal of medicinal chemistry (13.07.2023)
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Journal Article
Abstract 166: Identification of Grk2 as novel oncology target and development of potent Grk2 inhibitors
Lantermann, Alexandra, Chekler, Eugene, Lefker, Bruce, Yuen, Garmen, Lam, Vanessa, Strickland, Matthew, Pennacchio, Justyne, Fulgham, Aaron, Bree, Dara, Perekslis, Thomas, Piizzi, Grazia, Dai, Hongyue, Zheng, Tim, Wagner, John, Huang, Pearl
Published in Cancer research (Chicago, Ill.) (15.06.2022)
Published in Cancer research (Chicago, Ill.) (15.06.2022)
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Journal Article