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Discovery and preclinical characterization of [18F]PI-2620, a next-generation tau PET tracer for the assessment of tau pathology in Alzheimer’s disease and other tauopathies
Kroth, Heiko, Oden, Felix, Molette, Jerome, Schieferstein, Hanno, Capotosti, Francesca, Mueller, Andre, Berndt, Mathias, Schmitt-Willich, Heribert, Darmency, Vincent, Gabellieri, Emanuele, Boudou, Cédric, Juergens, Tanja, Varisco, Yvan, Vokali, Efthymia, Hickman, David T., Tamagnan, Gilles, Pfeifer, Andrea, Dinkelborg, Ludger, Muhs, Andreas, Stephens, Andrew
Published in European journal of nuclear medicine and molecular imaging (01.09.2019)
Published in European journal of nuclear medicine and molecular imaging (01.09.2019)
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Journal Article
The α-synuclein PET tracer [18F] ACI-12589 distinguishes multiple system atrophy from other neurodegenerative diseases
Smith, Ruben, Capotosti, Francesca, Schain, Martin, Ohlsson, Tomas, Vokali, Efthymia, Molette, Jerome, Touilloux, Tanja, Hliva, Valerie, Dimitrakopoulos, Ioannis K., Puschmann, Andreas, Jögi, Jonas, Svenningsson, Per, Andréasson, Mattias, Sandiego, Christine, Russell, David S., Miranda-Azpiazu, Patricia, Halldin, Christer, Stomrud, Erik, Hall, Sara, Bratteby, Klas, Tampio L’Estrade, Elina, Luthi-Carter, Ruth, Pfeifer, Andrea, Kosco-Vilbois, Marie, Streffer, Johannes, Hansson, Oskar
Published in Nature communications (27.10.2023)
Published in Nature communications (27.10.2023)
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Journal Article
Efficacy and Safety of A Liposome-Based Vaccine against Protein Tau, Assessed in Tau.P301L Mice That Model Tauopathy
Theunis, Clara, Crespo-Biel, Natalia, Gafner, Valérie, Pihlgren, Maria, López-Deber, María Pilar, Reis, Pedro, Hickman, David T., Adolfsson, Oskar, Chuard, Nathalie, Ndao, Dorin Mlaki, Borghgraef, Peter, Devijver, Herman, Van Leuven, Fred, Pfeifer, Andrea, Muhs, Andreas
Published in PloS one (19.08.2013)
Published in PloS one (19.08.2013)
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Journal Article
Aβ42 Neurotoxicity Is Mediated by Ongoing Nucleated Polymerization Process Rather than by Discrete Aβ42 Species
Jan, Asad, Adolfsson, Oskar, Allaman, Igor, Buccarello, Anna-Lucia, Magistretti, Pierre J., Pfeifer, Andrea, Muhs, Andreas, Lashuel, Hilal A.
Published in The Journal of biological chemistry (11.03.2011)
Published in The Journal of biological chemistry (11.03.2011)
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Journal Article
Immunotherapy targeting the C-terminal domain of TDP-43 decreases neuropathology and confers neuroprotection in mouse models of ALS/FTD
Afroz, Tariq, Chevalier, Elodie, Audrain, Mickael, Dumayne, Christopher, Ziehm, Tamar, Moser, Roger, Egesipe, Anne-Laure, Mottier, Lorène, Ratnam, Monisha, Neumann, Manuela, Havas, Daniel, Ollier, Romain, Piorkowska, Kasia, Chauhan, Mayank, Silva, Alberto B., Thapa, Samjhana, Stöhr, Jan, Bavdek, Andrej, Eligert, Valerie, Adolfsson, Oskar, Nelson, Peter T., Porta, Sílvia, Lee, Virginia M.-Y., Pfeifer, Andrea, Kosco-Vilbois, Marie, Seredenina, Tamara
Published in Neurobiology of disease (01.04.2023)
Published in Neurobiology of disease (01.04.2023)
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Journal Article
Correction: An Anti-β-Amyloid vaccine for treating cognitive deficits in a mouse model of down syndrome
Belichenko, Pavel V., Madani, Rime, Rey-Bellet, Lorianne, Pihlgren, Maria, Becker, Ann, Plassard, Adeline, Vuillermot, Stephanie, Giriens, Valérie, Nosheny, Rachel L., Kleschevnikov, Alexander M., Valletta, Janice S., Bengtsson, Sara K. S., Linke, Gordon R., Maloney, Michael T., Hickman, David T., Reis, Pedro, Granet, Anne, Mlaki, Dorin, Lopez-Deber, Maria Pilar, Do, Long, Singhal, Nishant, Masliah, Eliezer, Pearn, Matthew L., Pfeifer, Andrea, Muhs, Andreas, Mobley, William C.
Published in PloS one (2025)
Published in PloS one (2025)
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Journal Article
Antibody-Mediated Targeting of Tau In Vivo Does Not Require Effector Function and Microglial Engagement
Lee, Seung-Hye, Le Pichon, Claire E., Adolfsson, Oskar, Gafner, Valérie, Pihlgren, Maria, Lin, Han, Solanoy, Hilda, Brendza, Robert, Ngu, Hai, Foreman, Oded, Chan, Ruby, Ernst, James A., DiCara, Danielle, Hotzel, Isidro, Srinivasan, Karpagam, Hansen, David V., Atwal, Jasvinder, Lu, Yanmei, Bumbaca, Daniela, Pfeifer, Andrea, Watts, Ryan J., Muhs, Andreas, Scearce-Levie, Kimberly, Ayalon, Gai
Published in Cell reports (Cambridge) (09.08.2016)
Published in Cell reports (Cambridge) (09.08.2016)
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Journal Article
Calpain-mediated tau fragmentation is altered in Alzheimer’s disease progression
Chen, Hsu-Hsin, Liu, Peter, Auger, Paul, Lee, Seung-Hye, Adolfsson, Oskar, Rey-Bellet, Lorianne, Lafrance-Vanasse, Julien, Friedman, Brad A., Pihlgren, Maria, Muhs, Andreas, Pfeifer, Andrea, Ernst, James, Ayalon, Gai, Wildsmith, Kristin R., Beach, Thomas G., van der Brug, Marcel P.
Published in Scientific reports (13.11.2018)
Published in Scientific reports (13.11.2018)
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Journal Article
Modeling Alzheimer’s disease related phenotypes in the Ts65Dn mouse: impact of age on Aβ, Tau, pTau, NfL, and behavior
Overk, Cassia, Fiorini, Emma, Babolin, Chiara, Vukicevic, Marija, Morici, Catherine, Madani, Rime, Eligert, Valerie, Kosco-Vilbois, Marie, Roberts, Amanda, Becker, Ann, Pfeifer, Andrea, Mobley, William C.
Published in Frontiers in neuroscience (28.06.2023)
Published in Frontiers in neuroscience (28.06.2023)
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Journal Article
Targeting the TDP-43 low complexity domain blocks spreading of pathology in a mouse model of ALS/FTD
Chevalier, Elodie, Audrain, Mickael, Ratnam, Monisha, Ollier, Romain, Fuchs, Aline, Piorkowska, Kasia, Pfeifer, Andrea, Kosco-Vilbois, Marie, Seredenina, Tamara, Afroz, Tariq
Published in Acta neuropathologica communications (03.10.2024)
Published in Acta neuropathologica communications (03.10.2024)
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Journal Article
Improved antibody pharmacokinetics by disruption of contiguous positive surface potential and charge reduction using alternate human framework
Ollier, Romain, Fuchs, Aline, Gauye, Florence, Piorkowska, Katarzyna, Menant, Sébastien, Ratnam, Monisha, Montanari, Paolo, Guilhot, Florence, Phillipe, Didier, Audrain, Mickael, Egesipe, Anne-Laure, Névoltris, Damien, Seredenina, Tamara, Pfeifer, Andrea, Kosco-Vilbois, Marie, Afroz, Tariq
Published in mAbs (2023)
Published in mAbs (2023)
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Journal Article
Dynamics of GBF1, a Brefeldin A-Sensitive Arf1 Exchange Factor at the Golgi
Niu, Ting-Kuang, Pfeifer, Andrea C., Lippincott-Schwartz, Jennifer, Jackson, Catherine L.
Published in Molecular biology of the cell (01.03.2005)
Published in Molecular biology of the cell (01.03.2005)
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Journal Article
An Anti-β-Amyloid Vaccine for Treating Cognitive Deficits in a Mouse Model of Down Syndrome
Belichenko, Pavel V., Madani, Rime, Rey-Bellet, Lorianne, Pihlgren, Maria, Becker, Ann, Plassard, Adeline, Vuillermot, Stephanie, Giriens, Valérie, Nosheny, Rachel L., Kleschevnikov, Alexander M., Valletta, Janice S., Bengtsson, Sara K. S., Linke, Gordon R., Maloney, Michael T., Hickman, David T., Reis, Pedro, Granet, Anne, Mlaki, Dorin, Lopez-Deber, Maria Pilar, Do, Long, Singhal, Nishant, Masliah, Eliezer, Pearn, Matthew L., Pfeifer, Andrea, Muhs, Andreas, Mobley, William C.
Published in PloS one (29.03.2016)
Published in PloS one (29.03.2016)
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Journal Article
Evaluation of Dosimetry, Quantitative Methods, and Test–Retest Variability of 18F-PI-2620 PET for the Assessment of Tau Deposits in the Human Brain
Bullich, Santiago, Barret, Olivier, Constantinescu, Cristian, Sandiego, Christine, Mueller, Andre, Berndt, Mathias, Papin, Caroline, Perrotin, Audrey, Koglin, Norman, Kroth, Heiko, Pfeifer, Andrea, Tamagnan, Gilles, Madonia, Jennifer, Seibyl, John P, Marek, Kenneth, De Santi, Susan, Dinkelborg, Ludger M, Stephens, Andrew W
Published in The Journal of nuclear medicine (1978) (01.06.2020)
Published in The Journal of nuclear medicine (1978) (01.06.2020)
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Journal Article
Liposomal vaccines with conformation-specific amyloid peptide antigens define immune response and efficacy in APP transgenic mice
Muhs, Andreas, Hickman, David T, Pihlgren, Maria, Chuard, Nathalie, Giriens, Valérie, Meerschman, Carine, van der Auwera, Ingrid, van Leuven, Fred, Sugawara, Masae, Weingertner, Marie-Catherine, Bechinger, Burkhard, Greferath, Ruth, Kolonko, Nadine, Nagel-Steger, Luitgard, Riesner, Detlev, Brady, Roscoe O, Pfeifer, Andrea, Nicolau, Claude
Published in Proceedings of the National Academy of Sciences - PNAS (05.06.2007)
Published in Proceedings of the National Academy of Sciences - PNAS (05.06.2007)
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Journal Article
Andreas Römpp and Sabine Guenther win the ABC Best Paper Award
Oberbeckmann-Winter, Nicola, Pfeifer, Andrea
Published in Analytical and bioanalytical chemistry (01.09.2012)
Published in Analytical and bioanalytical chemistry (01.09.2012)
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Journal Article
Beneficial Effect of ACI-24 Vaccination on Aβ Plaque Pathology and Microglial Phenotypes in an Amyloidosis Mouse Model
Rudan Njavro, Jasenka, Vukicevic, Marija, Fiorini, Emma, Dinkel, Lina, Müller, Stephan A., Berghofer, Anna, Bordier, Chiara, Kozlov, Stanislav, Halle, Annett, Buschmann, Katrin, Capell, Anja, Giudici, Camilla, Willem, Michael, Feederle, Regina, Lichtenthaler, Stefan F., Babolin, Chiara, Montanari, Paolo, Pfeifer, Andrea, Kosco-Vilbois, Marie, Tahirovic, Sabina
Published in Cells (Basel, Switzerland) (24.12.2022)
Published in Cells (Basel, Switzerland) (24.12.2022)
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Journal Article
Quenched Substrates for Live-Cell Labeling of SNAP-Tagged Fusion Proteins with Improved Fluorescent Background
Stöhr, Katharina, Siegberg, Daniel, Ehrhard, Tanja, Lymperopoulos, Konstantinos, Öz, Simin, Schulmeister, Sonja, Pfeifer, Andrea C, Bachmann, Julie, Klingmüller, Ursula, Sourjik, Victor, Herten, Dirk-Peter
Published in Analytical chemistry (Washington) (01.10.2010)
Published in Analytical chemistry (Washington) (01.10.2010)
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Journal Article