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MEDI0382, a GLP‐1/glucagon receptor dual agonist, meets safety and tolerability endpoints in a single‐dose, healthy‐subject, randomized, Phase 1 study
Ambery, Philip D., Klammt, Sebastian, Posch, Maximillian G., Petrone, Marcella, Pu, Wenji, Rondinone, Cristina, Jermutus, Lutz, Hirshberg, Boaz
Published in British journal of clinical pharmacology (01.10.2018)
Published in British journal of clinical pharmacology (01.10.2018)
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Journal Article
Pharmacokinetics and Tolerability of a Single Dose of Semaglutide, a Human Glucagon-Like Peptide-1 Analog, in Subjects With and Without Renal Impairment
Marbury, Thomas C., Flint, Anne, Jacobsen, Jacob B., Derving Karsbøl, Julie, Lasseter, Kenneth
Published in Clinical pharmacokinetics (01.11.2017)
Published in Clinical pharmacokinetics (01.11.2017)
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Journal Article
Population Pharmacokinetics of Efsubaglutide Alfa in Healthy Subjects and Subjects with Type 2 Diabetes
Lou, Yan-Ru, Xu, Yu-Long, Xiong, Yifeng, Deng, Chenhui, Wang, Qinghua
Published in Clinical pharmacokinetics (01.04.2025)
Published in Clinical pharmacokinetics (01.04.2025)
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Journal Article
Cell-Penetrating Pepducin Therapy Targeting PAR1 in Subjects With Coronary Artery Disease
Gurbel, Paul A., Bliden, Kevin P., Turner, Susan E., Tantry, Udaya S., Gesheff, Martin G., Barr, Travis P., Covic, Lidija, Kuliopulos, Athan
Published in Arteriosclerosis, thrombosis, and vascular biology (01.01.2016)
Published in Arteriosclerosis, thrombosis, and vascular biology (01.01.2016)
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Journal Article
A phase 1, randomized, double‐blind, placebo‐controlled trial investigating the pharmacokinetics, pharmacodynamics, safety and tolerability of oral semaglutide in healthy Chinese subjects
Xie, Panpan, Abildlund, Morten T., Bækdal, Tine A., He, Xuemei, Lyauk, Yassine K., Patted, Usha Rani H., Ning, Zu, Shi, Aixin
Published in Diabetes, obesity & metabolism (01.08.2024)
Published in Diabetes, obesity & metabolism (01.08.2024)
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Journal Article
Absorption, metabolism and excretion of the GLP-1 analogue semaglutide in humans and nonclinical species
Jensen, Lene, Helleberg, Hans, Roffel, Ad, van Lier, Jan Jaap, Bjørnsdottir, Inga, Pedersen, Palle Jacob, Rowe, Everton, Derving Karsbøl, Julie, Pedersen, Mette Lund
Published in European journal of pharmaceutical sciences (15.06.2017)
Published in European journal of pharmaceutical sciences (15.06.2017)
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Journal Article
Effect of oral semaglutide on the pharmacokinetics of thyroxine after dosing of levothyroxine and the influence of co-administered tablets on the pharmacokinetics of oral semaglutide in healthy subjects: an open-label, one-sequence crossover, single-center, multiple-dose, two-part trial
Hauge, Camilla, Breitschaft, Astrid, Hartoft-Nielsen, Marie-Louise, Jensen, Simon, Bækdal, Tine A.
Published in Expert opinion on drug metabolism & toxicology (02.09.2021)
Published in Expert opinion on drug metabolism & toxicology (02.09.2021)
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Journal Article
Applications of pHLIP Technology for Cancer Imaging and Therapy
Wyatt, Linden C., Lewis, Jason S., Andreev, Oleg A., Reshetnyak, Yana K., Engelman, Donald M.
Published in Trends in biotechnology (Regular ed.) (01.07.2017)
Published in Trends in biotechnology (Regular ed.) (01.07.2017)
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Journal Article
Velcalcetide (AMG 416), a novel peptide agonist of the calcium-sensing receptor, reduces serum parathyroid hormone and FGF23 levels in healthy male subjects
Martin, K. J., Bell, G., Pickthorn, K., Huang, S., Vick, A., Hodsman, P., Peacock, M.
Published in Nephrology, dialysis, transplantation (01.02.2014)
Published in Nephrology, dialysis, transplantation (01.02.2014)
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Journal Article
A pharmacokinetic study comparing the biosimilar HEC14028 and Dulaglutide (Trulicity®) in healthy Chinese subjects
Gao, Xianglei, Di, Yujing, Lv, Yuan, Luan, Yingcai, Xiong, Yang, Xu, Yuli, Li, Yusheng, Guo, Linfeng, Li, Xiaoping, Deng, Li, Zhuang, Yulei, Hou, Jie
Published in Clinical and translational science (01.04.2024)
Published in Clinical and translational science (01.04.2024)
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Journal Article
Clinical Pharmacokinetics of Dulaglutide in Patients with Type 2 Diabetes: Analyses of Data from Clinical Trials
Geiser, Jeanne S., Heathman, Michael A., Cui, Xuewei, Martin, Jennifer, Loghin, Corina, Chien, Jenny Y., de la Peña, Amparo
Published in Clinical pharmacokinetics (01.05.2016)
Published in Clinical pharmacokinetics (01.05.2016)
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Journal Article
Safety, pharmacokinetics, and pharmacodynamics of oral apoA-I mimetic peptide D-4F in high-risk cardiovascular patients
Bloedon, LeAnne T., Dunbar, Richard, Duffy, Danielle, Pinell-Salles, Paula, Norris, Robert, DeGroot, Bruce J., Movva, Rajesh, Navab, Mohamad, Fogelman, Alan M., Rader, Daniel J.
Published in Journal of lipid research (01.06.2008)
Published in Journal of lipid research (01.06.2008)
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Journal Article
Population pharmacokinetics of exenatide
Cirincione, Brenda, Mager, Donald E.
Published in British journal of clinical pharmacology (01.03.2017)
Published in British journal of clinical pharmacology (01.03.2017)
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Journal Article
A first‐in‐man safety and pharmacokinetics study of nangibotide, a new modulator of innate immune response through TREM‐1 receptor inhibition
Cuvier, Valerie, Lorch, Ulrike, Witte, Stephan, Olivier, Aurelie, Gibot, Sebastien, Delor, Isabelle, Garaud, Jean‐Jacques, Derive, Marc, Salcedo‐Magguilli, Margarita
Published in British journal of clinical pharmacology (01.10.2018)
Published in British journal of clinical pharmacology (01.10.2018)
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Journal Article