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1060TiPRandomized, phase Ib/II study of M6620 + avelumab + carboplatin vs standard care (sc) in patients (pts) with platinum-sensitive poly (ADP-ribose) polymerase inhibitor-(PARPi)-resistant ovarian cancer
Banerjee, S, Vergotte, I, Colombo, N, Barve, M, Grisham, R, Mehr, K T, Falk, M, Beier, F, Hennessy, M, Schroeder, A, Birrer, M
Published in Annals of oncology (01.10.2019)
Published in Annals of oncology (01.10.2019)
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Journal Article
1060TiP - Randomized, phase Ib/II study of M6620 + avelumab + carboplatin vs standard care (sc) in patients (pts) with platinum-sensitive poly (ADP-ribose) polymerase inhibitor-(PARPi)-resistant ovarian cancer
Banerjee, S., Vergotte, I., Colombo, N., Barve, M., Grisham, R., Mehr, K.T., Falk, M., Beier, F., Hennessy, M., Schroeder, A., Birrer, M.
Published in Annals of oncology (01.10.2019)
Published in Annals of oncology (01.10.2019)
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Journal Article
A phase I study of a PARP1-targeted topical fluorophore for the detection of oral cancer
Demétrio de Souza França, Paula, Kossatz, Susanne, Brand, Christian, Karassawa Zanoni, Daniella, Roberts, Sheryl, Guru, Navjot, Adilbay, Dauren, Mauguen, Audrey, Valero Mayor, Cristina, Weber, Wolfgang A., Schöder, Heiko, Ghossein, Ronald A., Ganly, Ian, Patel, Snehal G., Reiner, Thomas
Published in European journal of nuclear medicine and molecular imaging (01.10.2021)
Published in European journal of nuclear medicine and molecular imaging (01.10.2021)
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Journal Article
PARPs, PAR and NAD Metabolism and Their Inhibitors in Cancer
Year of Publication 2023
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A Benchmark of In-House Homologous Recombination Repair Deficiency Testing Solutions for High-Grade Serous Ovarian Cancer Diagnosis
Guarischi-Sousa, Rodrigo, Kroll, José Eduardo, Bonaldi, Adriano, Pierry, Paulo Marques, Villela, Darine, Souza, Camila Alves, Silva, Juliana Santos, Bürger, Matheus Carvalho, Oliveira, Felipe Azevedo, de Paula, Marcelo Gomes, Meliso, Fabiana Marcelino, de Almeida, Luiz Gustavo, Monfredini, Priscilla Morais, de Oliveira, Ana Gabriela, Milanezi, Fernanda, Scapulatempo-Neto, Cristovam, Yamamoto, Guilherme Lopes
Published in Diagnostics (Basel) (01.10.2023)
Published in Diagnostics (Basel) (01.10.2023)
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Journal Article
[18F]FluorThanatrace ([18F]FTT) PET Imaging of PARP-Inhibitor Drug-Target Engagement as a Biomarker of Response in Ovarian Cancer, a Pilot Study
Pantel, Austin R., Gitto, Sarah B., Makvandi, Mehran, Kim, Hyoung, Medvedv, Sergey, Weeks, Joanna K., Torigian, Drew A., Hsieh, Chia-Ju, Ferman, Benjamin, Latif, Nawar A., Tanyi, Janos L., Martin, Lainie P., Lanzo, Shannon M., Liu, Fang, Cao, Quy, Mills, Gordon B., Doot, Robert K., Mankoff, David A., Mach, Robert H., Lin, Lilie L., Simpkins, Fiona
Published in Clinical cancer research (14.04.2023)
Published in Clinical cancer research (14.04.2023)
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Journal Article
BRCA1 intronic Alu elements drive gene rearrangements and PARP inhibitor resistance
Wang, Yifan, Bernhardy, Andrea J., Nacson, Joseph, Krais, John J., Tan, Yin-Fei, Nicolas, Emmanuelle, Radke, Marc R., Handorf, Elizabeth, Llop-Guevara, Alba, Balmaña, Judith, Swisher, Elizabeth M., Serra, Violeta, Peri, Suraj, Johnson, Neil
Published in Nature communications (11.12.2019)
Published in Nature communications (11.12.2019)
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Journal Article
[18F]FluorThanatrace PET imaging as a biomarker of response to PARP inhibitors in breast cancer
Gitto, Sarah B., Pantel, Austin R., Maxwell, Kara N., Pryma, Daniel A., Farwell, Michael D., Liu, Fang, Cao, Quy, O’Brien, Sophia R., Clark, Amy S., Shah, Payal D., McDonald, Elizabeth S.
Published in Communications medicine (25.03.2025)
Published in Communications medicine (25.03.2025)
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Journal Article
18FFluorThanatrace (18FFTT) PET Imaging of PARP-Inhibitor Drug-Target Engagement as a Biomarker of Response in Ovarian Cancer, a Pilot Study
Pantel, Austin R, Gitto, Sarah B, Makvandi, Mehran, Kim, Hyoung, Medvedv, Sergey, Weeks, Joanna K, Torigian, Drew A, Hsieh, Chia-Ju, Ferman, Benjamin, Latif, Nawar A, Tanyi, Janos L, Martin, Lainie P, Lanzo, Shannon M, Liu, Fang, Cao, Quy, Mills, Gordon B, Doot, Robert K, Mankoff, David A, Mach, Robert H, Lin, Lilie L, Simpkins, Fiona
Published in Clinical cancer research (14.04.2023)
Published in Clinical cancer research (14.04.2023)
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Journal Article
Second-line olaparib maintenance therapy is associated with poor response to subsequent chemotherapy in BRCA1/2-mutated epithelial ovarian cancer: A multicentre retrospective study
Park, Junsik, Kim, Se Ik, Jeong, Soo Young, Kim, Yup, Bookman, Michael A., Kim, Jae-Weon, Kim, Byoung-Gie, Lee, Jung-Yun
Published in Gynecologic oncology (01.04.2022)
Published in Gynecologic oncology (01.04.2022)
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Journal Article
31 Response to chemotherapy after treatment with a poly(ADP-ribose) polymerase inhibitor for patients with epithelial ovarian cancer
Marjon, Nicole, Kay, Allison, Papa, Franceed Horton, Tucker, Lue-Yen, Bookman, Michael A.A.
Published in Gynecologic oncology reports (01.12.2022)
Published in Gynecologic oncology reports (01.12.2022)
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Journal Article
18FFluorThanatrace PET imaging as a biomarker of response to PARP inhibitors in breast cancer
Gitto, Sarah B, Pantel, Austin R, Maxwell, Kara N, Pryma, Daniel A, Farwell, Michael D, Liu, Fang, Cao, Quy, O'Brien, Sophia R, Clark, Amy S, Shah, Payal D, McDonald, Elizabeth S
Published in Communications medicine (25.03.2025)
Published in Communications medicine (25.03.2025)
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Journal Article
Abstract P2-07-04: [18F]FluorThanatrace PET imaging correlates with response to PARP inhibitors in breast cancer: a pilot study
Pantel, Austin R., Maxwell, Kara, Young, Anthony, Pryma, Daniel A., Farwell, Michael D., Liu, Fang, Cao, Quy, O'Brien, Sophia R., Clark, Amy S., Shah, Payal D., McDonald, Elizabeth S.
Published in Clinical cancer research (13.06.2025)
Published in Clinical cancer research (13.06.2025)
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Journal Article
A phase II single-arm trial of niraparib in platinum-sensitive metastatic castration-resistant prostate cancer with DNA repair defects (PLATPARP)
Torres, Alexandra, Miller, Joann, Louie, Jennifer, Lee, Daniel, Haas, Naomi B., Takvorian, Samuel U, Maxwell, Kara Noelle, Domchek, Susan M., Narayan, Vivek
Published in Journal of clinical oncology (01.02.2024)
Published in Journal of clinical oncology (01.02.2024)
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Journal Article