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Inflammation-associated depression: From serotonin to kynurenine
Dantzer, Robert, O’Connor, Jason C., Lawson, Marcus A., Kelley, Keith W.
Published in Psychoneuroendocrinology (01.04.2011)
Published in Psychoneuroendocrinology (01.04.2011)
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Journal Article
DsbA-L prevents obesity-induced inflammation and insulin resistance by suppressing the mtDNA release-activated cGAS-cGAMP-STING pathway
Bai, Juli, Cervantes, Christopher, Liu, Juan, He, Sijia, Zhou, Haiyan, Zhang, Bilin, Cai, Huan, Yin, Dongqing, Hu, Derong, Li, Zhi, Chen, Hongzhi, Gao, Xiaoli, Wang, Fang, O’Connor, Jason C., Xu, Yong, Liu, Meilian, Dong, Lily Q., Liu, Feng
Published in Proceedings of the National Academy of Sciences - PNAS (14.11.2017)
Published in Proceedings of the National Academy of Sciences - PNAS (14.11.2017)
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Journal Article
Neuron-Derived Estrogen Regulates Synaptic Plasticity and Memory
Lu, Yujiao, Sareddy, Gangadhara R., Wang, Jing, Wang, Ruimin, Li, Yong, Dong, Yan, Zhang, Quanguang, Liu, Jinyou, O'Connor, Jason C., Xu, Jianhua, Vadlamudi, Ratna K., Brann, Darrell W.
Published in The Journal of neuroscience (10.04.2019)
Published in The Journal of neuroscience (10.04.2019)
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Journal Article
Kynurenine pathway metabolic balance influences microglia activity: Targeting kynurenine monooxygenase to dampen neuroinflammation
Garrison, Allison M., Parrott, Jennifer M., Tuñon, Arnulfo, Delgado, Jennifer, Redus, Laney, O’Connor, Jason C.
Published in Psychoneuroendocrinology (01.08.2018)
Published in Psychoneuroendocrinology (01.08.2018)
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Journal Article
Long-term benefits of hematopoietic stem cell-based macrophage/microglia delivery of GDNF to the CNS in a mouse model of Parkinson’s disease
Ge, Guo, Sivasubramanian, Barath P., Geng, Bill D., Zhao, Shujie, Zhou, Qing, Huang, Gang, O’Connor, Jason C., Clark, Robert A., Li, Senlin
Published in Gene therapy (01.05.2024)
Published in Gene therapy (01.05.2024)
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Journal Article
Neuropsychopharmacology of JNJ-55308942: evaluation of a clinical candidate targeting P2X7 ion channels in animal models of neuroinflammation and anhedonia
Bhattacharya, Anindya, Lord, Brian, Grigoleit, Jan-Sebastian, He, Yingbo, Fraser, Ian, Campbell, Shannon N., Taylor, Natalie, Aluisio, Leah, O’Connor, Jason C., Papp, Mariusz, Chrovian, Christa, Carruthers, Nicholas, Lovenberg, Timothy W., Letavic, Michael A.
Published in Neuropsychopharmacology (New York, N.Y.) (01.12.2018)
Published in Neuropsychopharmacology (New York, N.Y.) (01.12.2018)
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Journal Article
Brain derived neurotrophic factor deficiency exacerbates inflammation-induced anhedonia in mice
Parrott, Jennifer M., Porter, Grace A., Redus, Laney, O’Connor, Jason C.
Published in Psychoneuroendocrinology (01.12.2021)
Published in Psychoneuroendocrinology (01.12.2021)
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Journal Article
Cognitive Dysfunction Precedes the Onset of Motor Symptoms in the MitoPark Mouse Model of Parkinson’s Disease
Li, Xiuhua, Redus, Laney, Chen, Cang, Martinez, Paul A., Strong, Randy, Li, Senlin, O’Connor, Jason C.
Published in PloS one (15.08.2013)
Published in PloS one (15.08.2013)
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Journal Article
Tryptophan Metabolism in Patients With Chronic Kidney Disease Secondary to Type 2 Diabetes: Relationship to Inflammatory Markers
Debnath, Subrata, Velagapudi, Chakradhar, Redus, Laney, Thameem, Farook, Kasinath, Balakuntalam, Hura, Claudia E, Lorenzo, Carlos, Abboud, Hanna E, O’Connor, Jason C
Published in International journal of tryptophan research (2017)
Published in International journal of tryptophan research (2017)
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Journal Article
Intracerebroventricular administration of lipopolysaccharide induces indoleamine-2,3-dioxygenase-dependent depression-like behaviors
Lawson, Marcus A, Parrott, Jennifer M, McCusker, Robert H, Dantzer, Robert, Kelley, Keith W, O’Connor, Jason C
Published in Journal of neuroinflammation (18.07.2013)
Published in Journal of neuroinflammation (18.07.2013)
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Journal Article
GDNF-expressing macrophages mitigate loss of dopamine neurons and improve Parkinsonian symptoms in MitoPark mice
Chen, Cang, Li, Xiuhua, Ge, Guo, Liu, Jingwei, Biju, K. C., Laing, Suzette D., Qian, Yusheng, Ballard, Cori, He, Zhixu, Masliah, Eliezer, Clark, Robert A., O’Connor, Jason C., Li, Senlin
Published in Scientific reports (03.04.2018)
Published in Scientific reports (03.04.2018)
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Journal Article
Upregulation of neuronal kynurenine 3-monooxygenase mediates depression-like behavior in a mouse model of neuropathic pain
Laumet, Geoffroy, Zhou, Wenjun, Dantzer, Robert, Edralin, Jules D., Huo, XiaoJiao, Budac, David P., O'Connor, Jason C., Lee, Anna W., Heijnen, Cobi J., Kavelaars, Annemieke
Published in Brain, behavior, and immunity (01.11.2017)
Published in Brain, behavior, and immunity (01.11.2017)
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Journal Article
Microglia Transcriptome Changes in a Model of Depressive Behavior after Immune Challenge
Gonzalez-Pena, Dianelys, Nixon, Scott E., O’Connor, Jason C., Southey, Bruce R., Lawson, Marcus A., McCusker, Robert H., Borras, Tania, Machuca, Debbie, Hernandez, Alvaro G., Dantzer, Robert, Kelley, Keith W., Rodriguez-Zas, Sandra L.
Published in PloS one (09.03.2016)
Published in PloS one (09.03.2016)
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Journal Article
Randomization to Treadmill Training Improves Physical and Metabolic Health in Association With Declines in Oxidative Stress in Stroke
Serra, Monica C., Hafer-Macko, Charlene E., Robbins, Ronna, O'Connor, Jason C., Ryan, Alice S.
Published in Archives of physical medicine and rehabilitation (01.11.2022)
Published in Archives of physical medicine and rehabilitation (01.11.2022)
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Journal Article
Indoleamine 2,3-dioxygenase inhibition attenuates lipopolysaccharide induced persistent microglial activation and depressive-like complications in fractalkine receptor (CX3CR1)-deficient mice
Corona, Angela W., Norden, Diana M., Skendelas, John P., Huang, Yan, O’Connor, Jason C., Lawson, Marcus, Dantzer, Robert, Kelley, Keith W., Godbout, Jonathan P.
Published in Brain, behavior, and immunity (01.07.2013)
Published in Brain, behavior, and immunity (01.07.2013)
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Journal Article