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Genetics of circulating inflammatory proteins identifies drivers of immune-mediated disease risk and therapeutic targets
Zhao, Jing Hua, Stacey, David, Eriksson, Niclas, Macdonald-Dunlop, Erin, Hedman, Åsa K., Kalnapenkis, Anette, Enroth, Stefan, Cozzetto, Domenico, Digby-Bell, Jonathan, Marten, Jonathan, Folkersen, Lasse, Herder, Christian, Jonsson, Lina, Bergen, Sarah E., Gieger, Christian, Needham, Elise J., Surendran, Praveen, Paul, Dirk S., Polasek, Ozren, Thorand, Barbara, Grallert, Harald, Roden, Michael, Võsa, Urmo, Esko, Tonu, Hayward, Caroline, Johansson, Åsa, Gyllensten, Ulf, Powell, Nick, Hansson, Oskar, Mattsson-Carlgren, Niklas, Joshi, Peter K., Danesh, John, Padyukov, Leonid, Klareskog, Lars, Landén, Mikael, Wilson, James F., Siegbahn, Agneta, Wallentin, Lars, Mälarstig, Anders, Butterworth, Adam S., Peters, James E.
Published in Nature immunology (01.09.2023)
Published in Nature immunology (01.09.2023)
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Journal Article
Immunogenic cell stress and death
Kroemer, Guido, Galassi, Claudia, Zitvogel, Laurence, Galluzzi, Lorenzo
Published in Nature immunology (01.04.2022)
Published in Nature immunology (01.04.2022)
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Journal Article
Immunological dysfunction persists for 8 months following initial mild-to-moderate SARS-CoV-2 infection
Phetsouphanh, Chansavath, Darley, David R., Wilson, Daniel B., Howe, Annett, Munier, C. Mee Ling, Patel, Sheila K., Juno, Jennifer A., Burrell, Louise M., Kent, Stephen J., Dore, Gregory J., Kelleher, Anthony D., Matthews, Gail V.
Published in Nature immunology (01.02.2022)
Published in Nature immunology (01.02.2022)
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Journal Article
The complex role of tumor-infiltrating macrophages
Christofides, Anthos, Strauss, Laura, Yeo, Alan, Cao, Carol, Charest, Alain, Boussiotis, Vassiliki A.
Published in Nature immunology (01.08.2022)
Published in Nature immunology (01.08.2022)
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Journal Article
Broad and strong memory CD4+ and CD8+ T cells induced by SARS-CoV-2 in UK convalescent individuals following COVID-19
Peng, Yanchun, Mentzer, Alexander J., Liu, Guihai, Yao, Xuan, Yin, Zixi, Dong, Danning, Dejnirattisai, Wanwisa, Rostron, Timothy, Supasa, Piyada, Liu, Chang, López-Camacho, César, Slon-Campos, Jose, Zhao, Yuguang, Stuart, David I., Paesen, Guido C., Grimes, Jonathan M., Antson, Alfred A., Bayfield, Oliver W., Hawkins, Dorothy E. D. P., Ker, De-Sheng, Wang, Beibei, Turtle, Lance, Subramaniam, Krishanthi, Thomson, Paul, Zhang, Ping, Dold, Christina, Ratcliff, Jeremy, Simmonds, Peter, de Silva, Thushan, Sopp, Paul, Wellington, Dannielle, Rajapaksa, Ushani, Chen, Yi-Ling, Salio, Mariolina, Napolitani, Giorgio, Paes, Wayne, Borrow, Persephone, Kessler, Benedikt M., Fry, Jeremy W., Schwabe, Nikolai F., Semple, Malcolm G., Baillie, J. Kenneth, Moore, Shona C., Openshaw, Peter J. M., Ansari, M. Azim, Dunachie, Susanna, Barnes, Eleanor, Frater, John, Kerr, Georgina, Goulder, Philip, Lockett, Teresa, Levin, Robert, Zhang, Yonghong, Jing, Ronghua, Ho, Ling-Pei, Cornall, Richard J., Conlon, Christopher P., Klenerman, Paul, Screaton, Gavin R., Mongkolsapaya, Juthathip, McMichael, Andrew, Knight, Julian C., Ogg, Graham, Dong, Tao
Published in Nature immunology (01.11.2020)
Published in Nature immunology (01.11.2020)
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Journal Article
Reference-based analysis of lung single-cell sequencing reveals a transitional profibrotic macrophage
Aran, Dvir, Looney, Agnieszka P., Liu, Leqian, Wu, Esther, Fong, Valerie, Hsu, Austin, Chak, Suzanna, Naikawadi, Ram P., Wolters, Paul J., Abate, Adam R., Butte, Atul J., Bhattacharya, Mallar
Published in Nature immunology (01.02.2019)
Published in Nature immunology (01.02.2019)
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Journal Article
SARS-CoV-2 infection of human ACE2-transgenic mice causes severe lung inflammation and impaired function
Winkler, Emma S., Bailey, Adam L., Kafai, Natasha M., Nair, Sharmila, McCune, Broc T., Yu, Jinsheng, Fox, Julie M., Chen, Rita E., Earnest, James T., Keeler, Shamus P., Ritter, Jon H., Kang, Liang-I, Dort, Sarah, Robichaud, Annette, Head, Richard, Holtzman, Michael J., Diamond, Michael S.
Published in Nature immunology (01.11.2020)
Published in Nature immunology (01.11.2020)
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Journal Article
FDA-approved disulfiram inhibits pyroptosis by blocking gasdermin D pore formation
Hu, Jun Jacob, Liu, Xing, Xia, Shiyu, Zhang, Zhibin, Zhang, Ying, Zhao, Jingxia, Ruan, Jianbin, Luo, Xuemei, Lou, Xiwen, Bai, Yang, Wang, Junhong, Hollingsworth, L. Robert, Magupalli, Venkat Giri, Zhao, Li, Luo, Hongbo R., Kim, Justin, Lieberman, Judy, Wu, Hao
Published in Nature immunology (01.07.2020)
Published in Nature immunology (01.07.2020)
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Journal Article
Extrafollicular B cell responses correlate with neutralizing antibodies and morbidity in COVID-19
Woodruff, Matthew C., Ramonell, Richard P., Nguyen, Doan C., Cashman, Kevin S., Saini, Ankur Singh, Haddad, Natalie S., Ley, Ariel M., Kyu, Shuya, Howell, J. Christina, Ozturk, Tugba, Lee, Saeyun, Suryadevara, Naveenchandra, Case, James Brett, Bugrovsky, Regina, Chen, Weirong, Estrada, Jacob, Morrison-Porter, Andrea, Derrico, Andrew, Anam, Fabliha A., Sharma, Monika, Wu, Henry M., Le, Sang N., Jenks, Scott A., Tipton, Christopher M., Staitieh, Bashar, Daiss, John L., Ghosn, Eliver, Diamond, Michael S., Carnahan, Robert H., Crowe, James E., Hu, William T., Lee, F. Eun-Hyung, Sanz, Ignacio
Published in Nature immunology (01.12.2020)
Published in Nature immunology (01.12.2020)
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Journal Article
The PD-1 expression balance between effector and regulatory T cells predicts the clinical efficacy of PD-1 blockade therapies
Kumagai, Shogo, Togashi, Yosuke, Kamada, Takahiro, Sugiyama, Eri, Nishinakamura, Hitomi, Takeuchi, Yoshiko, Vitaly, Kochin, Itahashi, Kota, Maeda, Yuka, Matsui, Shigeyuki, Shibahara, Takuma, Yamashita, Yasuho, Irie, Takuma, Tsuge, Ayaka, Fukuoka, Shota, Kawazoe, Akihito, Udagawa, Hibiki, Kirita, Keisuke, Aokage, Keiju, Ishii, Genichiro, Kuwata, Takeshi, Nakama, Kenta, Kawazu, Masahito, Ueno, Toshihide, Yamazaki, Naoya, Goto, Koichi, Tsuboi, Masahiro, Mano, Hiroyuki, Doi, Toshihiko, Shitara, Kohei, Nishikawa, Hiroyoshi
Published in Nature immunology (01.11.2020)
Published in Nature immunology (01.11.2020)
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Journal Article
Mitochondrial stress induced by continuous stimulation under hypoxia rapidly drives T cell exhaustion
Scharping, Nicole E., Rivadeneira, Dayana B., Menk, Ashley V., Vignali, Paolo D. A., Ford, B. Rhodes, Rittenhouse, Natalie L., Peralta, Ronal, Wang, Yiyang, Wang, Yupeng, DePeaux, Kristin, Poholek, Amanda C., Delgoffe, Greg M.
Published in Nature immunology (01.02.2021)
Published in Nature immunology (01.02.2021)
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Journal Article
Subsets of exhausted CD8+ T cells differentially mediate tumor control and respond to checkpoint blockade
Miller, Brian C., Sen, Debattama R., Al Abosy, Rose, Bi, Kevin, Virkud, Yamini V., LaFleur, Martin W., Yates, Kathleen B., Lako, Ana, Felt, Kristen, Naik, Girish S., Manos, Michael, Gjini, Evisa, Kuchroo, Juhi R., Ishizuka, Jeffrey J., Collier, Jenna L., Griffin, Gabriel K., Maleri, Seth, Comstock, Dawn E., Weiss, Sarah A., Brown, Flavian D., Panda, Arpit, Zimmer, Margaret D., Manguso, Robert T., Hodi, F. Stephen, Rodig, Scott J., Sharpe, Arlene H., Haining, W. Nicholas
Published in Nature immunology (01.03.2019)
Published in Nature immunology (01.03.2019)
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Journal Article
IL-1 and IL-1ra are key regulators of the inflammatory response to RNA vaccines
Tahtinen, Siri, Tong, Ann-Jay, Himmels, Patricia, Oh, Jaehak, Paler-Martinez, Andres, Kim, Leesun, Wichner, Sara, Oei, Yoko, McCarron, Mark J., Freund, Emily C., Amir, Zhainib Adel, de la Cruz, Cecile C., Haley, Benjamin, Blanchette, Craig, Schartner, Jill M., Ye, Weilan, Yadav, Mahesh, Sahin, Ugur, Delamarre, Lélia, Mellman, Ira
Published in Nature immunology (01.04.2022)
Published in Nature immunology (01.04.2022)
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Journal Article
Mechanisms of innate and adaptive immunity to the Pfizer-BioNTech BNT162b2 vaccine
Li, Chunfeng, Lee, Audrey, Grigoryan, Lilit, Arunachalam, Prabhu S., Scott, Madeleine K. D., Trisal, Meera, Wimmers, Florian, Sanyal, Mrinmoy, Weidenbacher, Payton A., Feng, Yupeng, Adamska, Julia Z., Valore, Erika, Wang, Yanli, Verma, Rohit, Reis, Noah, Dunham, Diane, O’Hara, Ruth, Park, Helen, Luo, Wei, Gitlin, Alexander D., Kim, Peter, Khatri, Purvesh, Nadeau, Kari C., Pulendran, Bali
Published in Nature immunology (01.04.2022)
Published in Nature immunology (01.04.2022)
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Journal Article