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Pharmacologic Inhibition of the Menin-MLL Interaction Blocks Progression of MLL Leukemia In Vivo
Borkin, Dmitry, He, Shihan, Miao, Hongzhi, Kempinska, Katarzyna, Pollock, Jonathan, Chase, Jennifer, Purohit, Trupta, Malik, Bhavna, Zhao, Ting, Wang, Jingya, Wen, Bo, Zong, Hongliang, Jones, Morgan, Danet-Desnoyers, Gwenn, Guzman, Monica L., Talpaz, Moshe, Bixby, Dale L., Sun, Duxin, Hess, Jay L., Muntean, Andrew G., Maillard, Ivan, Cierpicki, Tomasz, Grembecka, Jolanta
Published in Cancer cell (13.04.2015)
Published in Cancer cell (13.04.2015)
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Journal Article
Menin-MLL inhibitors reverse oncogenic activity of MLL fusion proteins in leukemia
Grembecka, Jolanta, He, Shihan, Shi, Aibin, Purohit, Trupta, Muntean, Andrew G, Sorenson, Roderick J, Showalter, Hollis D, Murai, Marcelo J, Belcher, Amalia M, Hartley, Thomas, Hess, Jay L, Cierpicki, Tomasz
Published in Nature chemical biology (29.01.2012)
Published in Nature chemical biology (29.01.2012)
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Journal Article
CBX8, a Polycomb Group Protein, Is Essential for MLL-AF9-Induced Leukemogenesis
Tan, Jiaying, Jones, Morgan, Koseki, Haruhiko, Nakayama, Manabu, Muntean, Andrew G., Maillard, Ivan, Hess, Jay L.
Published in Cancer cell (15.11.2011)
Published in Cancer cell (15.11.2011)
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Journal Article
C/EBPα is an essential collaborator in Hoxa9/Meis1-mediated leukemogenesis
Collins, Cailin, Wang, Jingya, Miao, Hongzhi, Bronstein, Joel, Nawer, Humaira, Xu, Tao, Figueroa, Maria, Muntean, Andrew G., Hess, Jay L.
Published in Proceedings of the National Academy of Sciences - PNAS (08.07.2014)
Published in Proceedings of the National Academy of Sciences - PNAS (08.07.2014)
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Journal Article
The same site on the integrase-binding domain of lens epithelium–derived growth factor is a therapeutic target for MLL leukemia and HIV
Murai, Marcelo J., Pollock, Jonathan, He, Shihan, Miao, Hongzhi, Purohit, Trupta, Yokom, Adam, Hess, Jay L., Muntean, Andrew G., Grembecka, Jolanta, Cierpicki, Tomasz
Published in Blood (11.12.2014)
Published in Blood (11.12.2014)
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Journal Article
The PAF1c Subunit CDC73 Is Required for Mouse Hematopoietic Stem Cell Maintenance but Displays Leukemia-Specific Gene Regulation
Saha, Nirmalya, Ropa, James, Chen, Lili, Hu, Hsiangyu, Mysliwski, Maria, Friedman, Ann, Maillard, Ivan, Muntean, Andrew G.
Published in Stem cell reports (14.05.2019)
Published in Stem cell reports (14.05.2019)
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Journal Article
CYR61 (CCN1) Is Essential for Placental Development and Vascular Integrity
Mo, Fan-E, Muntean, Andrew G., Chen, Chih-Chiun, Stolz, Donna B., Watkins, Simon C., Lau, Lester F.
Published in Molecular and Cellular Biology (01.12.2002)
Published in Molecular and Cellular Biology (01.12.2002)
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Journal Article
Cyclin D–Cdk4 is regulated by GATA-1 and required for megakaryocyte growth and polyploidization
Muntean, Andrew G., Pang, Liyan, Poncz, Mortimer, Dowdy, Steven F., Blobel, Gerd A., Crispino, John D.
Published in Blood (15.06.2007)
Published in Blood (15.06.2007)
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Journal Article
The ENL YEATS epigenetic reader domain critically links MLL-ENL to leukemic stem cell frequency in t(11;19) Leukemia
Hu, Hsiangyu, Saha, Nirmalya, Yang, Yuting, Ahmad, Ejaz, Lachowski, Lauren, Shrestha, Uttar, Premkumar, Vidhya, Ropa, James, Chen, Lili, Teahan, Blaine, Grigsby, Sierrah, Marschalek, Rolf, Nikolovska-Coleska, Zaneta, Muntean, Andrew G.
Published in Leukemia (01.01.2023)
Published in Leukemia (01.01.2023)
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Journal Article
Cdc73 protects Notch-induced T-cell leukemia cells from DNA damage and mitochondrial stress
Melnick, Ashley F., Mullin, Carea, Lin, Karena, McCarter, Anna C., Liang, Shannon, Liu, Yiran E., Wang, Qing, Jerome, Nicole A., Choe, Elizabeth, Kunnath, Nicholas, Bodanapu, Geethika, Akter, Fatema, Magnuson, Brian, Kumar, Surinder, Lombard, David B., Muntean, Andrew G., Ljungman, Mats, Sekiguchi, JoAnn, Ryan, Russell J. H., Chiang, Mark Y.
Published in Blood (21.12.2023)
Published in Blood (21.12.2023)
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Journal Article
The PAF Complex Synergizes with MLL Fusion Proteins at HOX Loci to Promote Leukemogenesis
Muntean, Andrew G., Tan, Jiaying, Sitwala, Kajal, Huang, Yongsheng, Bronstein, Joel, Connelly, James A., Basrur, Venkatesha, Elenitoba-Johnson, Kojo S.J., Hess, Jay L.
Published in Cancer cell (15.06.2010)
Published in Cancer cell (15.06.2010)
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Journal Article
A Subset of Mixed Lineage Leukemia Proteins Has Plant Homeodomain (PHD)-mediated E3 Ligase Activity
Wang, Jingya, Muntean, Andrew G., Wu, Laura, Hess, Jay L.
Published in The Journal of biological chemistry (21.12.2012)
Published in The Journal of biological chemistry (21.12.2012)
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Journal Article
Differential regulation of the c-Myc/Lin28 axis discriminates subclasses of rearranged MLL leukemia
Chen, Lili, Sun, Yuqing, Wang, Jingya, Jiang, Hui, Muntean, Andrew G.
Published in Oncotarget (03.05.2016)
Published in Oncotarget (03.05.2016)
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Journal Article