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Biocompatible, Purified VEGF-A mRNA Improves Cardiac Function after Intracardiac Injection 1 Week Post-myocardial Infarction in Swine
Carlsson, Leif, Clarke, Jonathan C., Yen, Christopher, Gregoire, Francine, Albery, Tamsin, Billger, Martin, Egnell, Ann-Charlotte, Gan, Li-Ming, Jennbacken, Karin, Johansson, Edvin, Linhardt, Gunilla, Martinsson, Sofia, Sadiq, Muhammad Waqas, Witman, Nevin, Wang, Qing-Dong, Chen, Chien-Hsi, Wang, Yu-Ping, Lin, Susan, Ticho, Barry, Hsieh, Patrick C.H., Chien, Kenneth R., Fritsche-Danielson, Regina
Published in Molecular therapy. Methods & clinical development (15.06.2018)
Published in Molecular therapy. Methods & clinical development (15.06.2018)
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Journal Article
Airways Expression of SARS-CoV-2 Receptor, ACE2, and TMPRSS2 Is Lower in Children Than Adults and Increases with Smoking and COPD
Saheb Sharif-Askari, Narjes, Saheb Sharif-Askari, Fatemeh, Alabed, Mashael, Temsah, Mohamed-Hani, Al Heialy, Saba, Hamid, Qutayba, Halwani, Rabih
Published in Molecular therapy. Methods & clinical development (11.09.2020)
Published in Molecular therapy. Methods & clinical development (11.09.2020)
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Journal Article
Barriers and Strategies of Cationic Liposomes for Cancer Gene Therapy
Liu, Chunyan, Zhang, Ligang, Zhu, Wenhui, Guo, Raoqing, Sun, Huamin, Chen, Xi, Deng, Ning
Published in Molecular therapy. Methods & clinical development (11.09.2020)
Published in Molecular therapy. Methods & clinical development (11.09.2020)
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Journal Article
Global Manufacturing of CAR T Cell Therapy
Levine, Bruce L., Miskin, James, Wonnacott, Keith, Keir, Christopher
Published in Molecular therapy. Methods & clinical development (17.03.2017)
Published in Molecular therapy. Methods & clinical development (17.03.2017)
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Journal Article
Capsid Modifications for Targeting and Improving the Efficacy of AAV Vectors
Büning, Hildegard, Srivastava, Arun
Published in Molecular therapy. Methods & clinical development (15.03.2019)
Published in Molecular therapy. Methods & clinical development (15.03.2019)
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Journal Article
Oncolytic Viruses and the Immune System: The Dynamic Duo
Lemos de Matos, Ana, Franco, Lina S., McFadden, Grant
Published in Molecular therapy. Methods & clinical development (12.06.2020)
Published in Molecular therapy. Methods & clinical development (12.06.2020)
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Journal Article
Analytical methods for process and product characterization of recombinant adeno-associated virus-based gene therapies
Gimpel, Andreas L., Katsikis, Georgios, Sha, Sha, Maloney, Andrew John, Hong, Moo Sun, Nguyen, Tam N.T., Wolfrum, Jacqueline, Springs, Stacy L., Sinskey, Anthony J., Manalis, Scott R., Barone, Paul W., Braatz, Richard D.
Published in Molecular therapy. Methods & clinical development (12.03.2021)
Published in Molecular therapy. Methods & clinical development (12.03.2021)
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Journal Article
The Two Faces of ACE2: The Role of ACE2 Receptor and Its Polymorphisms in Hypertension and COVID-19
Bosso, Mira, Thanaraj, Thangavel Alphonse, Abu-Farha, Mohamed, Alanbaei, Muath, Abubaker, Jehad, Al-Mulla, Fahd
Published in Molecular therapy. Methods & clinical development (11.09.2020)
Published in Molecular therapy. Methods & clinical development (11.09.2020)
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Journal Article
Methods Matter: Standard Production Platforms for Recombinant AAV Produce Chemically and Functionally Distinct Vectors
Rumachik, Neil G., Malaker, Stacy A., Poweleit, Nicole, Maynard, Lucy H., Adams, Christopher M., Leib, Ryan D., Cirolia, Giana, Thomas, Dennis, Stamnes, Susan, Holt, Kathleen, Sinn, Patrick, May, Andrew P., Paulk, Nicole K.
Published in Molecular therapy. Methods & clinical development (11.09.2020)
Published in Molecular therapy. Methods & clinical development (11.09.2020)
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Journal Article
Improved Loading of Plasma-Derived Extracellular Vesicles to Encapsulate Antitumor miRNAs
Pomatto, Margherita Alba Carlotta, Bussolati, Benedetta, D’Antico, Sergio, Ghiotto, Sara, Tetta, Ciro, Brizzi, Maria Felice, Camussi, Giovanni
Published in Molecular therapy. Methods & clinical development (14.06.2019)
Published in Molecular therapy. Methods & clinical development (14.06.2019)
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Journal Article
Prevalence of Anti-Adeno-Associated Virus Immune Responses in International Cohorts of Healthy Donors
Kruzik, Anita, Fetahagic, Damir, Hartlieb, Bettina, Dorn, Sebastian, Koppensteiner, Herwig, Horling, Frank M., Scheiflinger, Friedrich, Reipert, Birgit M., de la Rosa, Maurus
Published in Molecular therapy. Methods & clinical development (13.09.2019)
Published in Molecular therapy. Methods & clinical development (13.09.2019)
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Journal Article
CNS Transduction Benefits of AAV-PHP.eB over AAV9 Are Dependent on Administration Route and Mouse Strain
Mathiesen, Sophie N., Lock, Jasmine L., Schoderboeck, Lucia, Abraham, Wickliffe C., Hughes, Stephanie M.
Published in Molecular therapy. Methods & clinical development (11.12.2020)
Published in Molecular therapy. Methods & clinical development (11.12.2020)
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Journal Article
Synthetic mRNA Encoding VEGF-A in Patients Undergoing Coronary Artery Bypass Grafting: Design of a Phase 2a Clinical Trial
Anttila, Vesa, Saraste, Antti, Knuuti, Juhani, Jaakkola, Pekka, Hedman, Marja, Svedlund, Sara, Lagerström-Fermér, Maria, Kjaer, Magnus, Jeppsson, Anders, Gan, Li-Ming
Published in Molecular therapy. Methods & clinical development (11.09.2020)
Published in Molecular therapy. Methods & clinical development (11.09.2020)
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Journal Article
Rapid evolution of blood-brain-barrier-penetrating AAV capsids by RNA-driven biopanning
Nonnenmacher, Mathieu, Wang, Wei, Child, Matthew A., Ren, Xiao-Qin, Huang, Carol, Ren, Amy Zhen, Tocci, Jenna, Chen, Qingmin, Bittner, Kelsey, Tyson, Katherine, Pande, Nilesh, Chung, Charlotte Hiu-Yan, Paul, Steven M., Hou, Jay
Published in Molecular therapy. Methods & clinical development (12.03.2021)
Published in Molecular therapy. Methods & clinical development (12.03.2021)
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Journal Article
Use of Nanovesicles from Orange Juice to Reverse Diet-Induced Gut Modifications in Diet-Induced Obese Mice
Berger, Emmanuelle, Colosetti, Pascal, Jalabert, Audrey, Meugnier, Emmanuelle, Wiklander, Oscar P.B., Jouhet, Juliette, Errazurig-Cerda, Elisabeth, Chanon, Stéphanie, Gupta, Dhanu, Rautureau, Gilles J.P., Geloen, Alain, El-Andaloussi, Samir, Panthu, Baptiste, Rieusset, Jennifer, Rome, Sophie
Published in Molecular therapy. Methods & clinical development (11.09.2020)
Published in Molecular therapy. Methods & clinical development (11.09.2020)
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Journal Article
Production and clinical development of nanoparticles for gene delivery
Chen, Jie, Guo, Zhaopei, Tian, Huayu, Chen, Xuesi
Published in Molecular therapy. Methods & clinical development (01.01.2016)
Published in Molecular therapy. Methods & clinical development (01.01.2016)
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Journal Article
Comparison of analytical techniques to quantitate the capsid content of adeno-associated viral vectors
Werle, Amanda K., Powers, Thomas W., Zobel, James F., Wappelhorst, Caitlin N., Jarrold, Martin F., Lyktey, Nicholas A., Sloan, Courtney D.K., Wolf, Andrew J., Adams-Hall, Sharee, Baldus, Phoebe, Runnels, Herbert A.
Published in Molecular therapy. Methods & clinical development (10.12.2021)
Published in Molecular therapy. Methods & clinical development (10.12.2021)
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Journal Article
Acerola exosome-like nanovesicles to systemically deliver nucleic acid medicine via oral administration
Umezu, Tomohiro, Takanashi, Masakatsu, Murakami, Yoshiki, Ohno, Shin-ichiro, Kanekura, Kohsuke, Sudo, Katsuko, Nagamine, Kenichi, Takeuchi, Shin, Ochiya, Takahiro, Kuroda, Masahiko
Published in Molecular therapy. Methods & clinical development (11.06.2021)
Published in Molecular therapy. Methods & clinical development (11.06.2021)
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Journal Article
Influence of Pre-existing Anti-capsid Neutralizing and Binding Antibodies on AAV Vector Transduction
Fitzpatrick, Zachary, Leborgne, Christian, Barbon, Elena, Masat, Elisa, Ronzitti, Giuseppe, van Wittenberghe, Laetitia, Vignaud, Alban, Collaud, Fanny, Charles, Séverine, Simon Sola, Marcelo, Jouen, Fabienne, Boyer, Olivier, Mingozzi, Federico
Published in Molecular therapy. Methods & clinical development (15.06.2018)
Published in Molecular therapy. Methods & clinical development (15.06.2018)
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Journal Article