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Brown fat activation reduces hypercholesterolaemia and protects from atherosclerosis development
Berbée, Jimmy F. P., Boon, Mariëtte R, Khedoe, P. Padmini S. J., Bartelt, Alexander, Schlein, Christian, Worthmann, Anna, Kooijman, Sander, Hoeke, Geerte, Mol, Isabel M., John, Clara, Jung, Caroline, Vazirpanah, Nadia, Brouwers, Linda P.J., Gordts, Philip L.S.M., Esko, Jeffrey D., Hiemstra, Pieter S., Havekes, Louis M., Scheja, Ludger, Heeren, Joerg, Rensen, Patrick C.N.
Published in Nature communications (10.03.2015)
Published in Nature communications (10.03.2015)
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Journal Article
Genome-wide coexpression of steroid receptors in the mouse brain: Identifying signaling pathways and functionally coordinated regions
Mahfouz, Ahmed, Lelieveldt, Boudewijn P. F., Grefhorst, Aldo, van Weert, Lisa T. C. M., Mol, Isabel M., Sips, Hetty C. M., van den Heuvel, José K., Datson, Nicole A., Visser, Jenny A., Reinders, Marcel J. T., Meijer, Onno C.
Published in Proceedings of the National Academy of Sciences - PNAS (08.03.2016)
Published in Proceedings of the National Academy of Sciences - PNAS (08.03.2016)
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Journal Article
The GPR120 agonist TUG‐891 promotes metabolic health by stimulating mitochondrial respiration in brown fat
Schilperoort, Maaike, van Dam, Andrea D, Hoeke, Geerte, Shabalina, Irina G, Okolo, Anthony, Hanyaloglu, Aylin C, Dib, Lea H, Mol, Isabel M, Caengprasath, Natarin, Chan, Yi‐Wah, Damak, Sami, Miller, Anne Reifel, Coskun, Tamer, Shimpukade, Bharat, Ulven, Trond, Kooijman, Sander, Rensen, Patrick CN, Christian, Mark
Published in EMBO molecular medicine (01.03.2018)
Published in EMBO molecular medicine (01.03.2018)
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Journal Article
Selective Glucocorticoid Receptor Antagonist CORT125281 Activates Brown Adipose Tissue and Alters Lipid Distribution in Male Mice
Kroon, Jan, Koorneef, Lisa L, van den Heuvel, Jose K, Verzijl, Cristy R C, van de Velde, Nienke M, Mol, Isabel M, Sips, Hetty C M, Hunt, Hazel, Rensen, Patrick C N, Meijer, Onno C
Published in Endocrinology (Philadelphia) (01.01.2018)
Published in Endocrinology (Philadelphia) (01.01.2018)
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Journal Article
Deuterium-reinforced polyunsaturated fatty acids protect against atherosclerosis by lowering lipid peroxidation and hypercholesterolemia
Berbée, Jimmy F.P., Mol, Isabel M., Milne, Ginger L., Pollock, Erik, Hoeke, Geerte, Lütjohann, Dieter, Monaco, Claudia, Rensen, Patrick C.N., van der Ploeg, Lex H.T., Shchepinov, Mikhail S.
Published in Atherosclerosis (01.09.2017)
Published in Atherosclerosis (01.09.2017)
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Journal Article
Atorvastatin accelerates clearance of lipoprotein remnants generated by activated brown fat to further reduce hypercholesterolemia and atherosclerosis
Hoeke, Geerte, Wang, Yanan, van Dam, Andrea D., Mol, Isabel M., Gart, Eveline, Klop, Henk G., van den Berg, Susan M., Pieterman, Elsbet H., Princen, Hans M.G., Groen, Albert K., Rensen, Patrick C.N., Berbée, Jimmy F.P., Boon, Mariëtte R.
Published in Atherosclerosis (01.12.2017)
Published in Atherosclerosis (01.12.2017)
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Journal Article
Spatial and temporal expression of immunoglobulin superfamily member 1 in the rat
Joustra, Sjoerd D, Meijer, Onno C, Heinen, Charlotte A, Mol, Isabel M, Laghmani, El Houari, Sengers, Rozemarijn M A, Carreno, Gabriela, van Trotsenburg, A S Paul, Biermasz, Nienke R, Bernard, Daniel J, Wit, Jan M, Oostdijk, Wilma, van Pelt, Ans M M, Hamer, Geert, Wagenaar, Gerry T M
Published in Journal of endocrinology (01.09.2015)
Published in Journal of endocrinology (01.09.2015)
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Journal Article
A physiological glucocorticoid rhythm is an important regulator of brown adipose tissue function
Kroon, Jan, Schilperoort, Maaike, In het Panhuis, Wietse, van den Berg, Rosa, van Doeselaar, Lotte, Verzijl, Cristy R.C., van Trigt, Nikki, Mol, Isabel M., Sips, Hetty H.C.M., van den Heuvel, Jose K., Koorneef, Lisa L., van der Sluis, Ronald J., Fenzl, Anna, Kiefer, Florian W., Vettorazzi, Sabine, Tuckermann, Jan P., Biermasz, Nienke R., Meijer, Onno C., Rensen, Patrick C.N., Kooijman, Sander
Published in Molecular metabolism (Germany) (01.05.2021)
Published in Molecular metabolism (Germany) (01.05.2021)
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Journal Article
Dual-Wavelength Imaging of Tumor Progression by Activatable and Targeting Near-Infrared Fluorescent Probes in a Bioluminescent Breast Cancer Model
Xie, Bang-Wen, Mol, Isabel M., Keereweer, Stijn, van Beek, Ermond R., Que, Ivo, Snoeks, Thomas J. A., Chan, Alan, Kaijzel, Eric L., Löwik, Clemens W. G. M.
Published in PloS one (13.02.2012)
Published in PloS one (13.02.2012)
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Journal Article
Targeting integrins and enhanced permeability and retention (EPR) effect for optical imaging of oral cancer
Keereweer, Stijn, Mol, Isabel M., Kerrebijn, Jeroen D.F., Van Driel, Pieter B.A.A., Xie, Bangwen, Baatenburg de Jong, Robert J., Vahrmeijer, Alexander L., Löwik, Clemens W.G.M.
Published in Journal of surgical oncology (01.06.2012)
Published in Journal of surgical oncology (01.06.2012)
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Journal Article
Quercetin Lowers Plasma Triglycerides Accompanied by White Adipose Tissue Browning in Diet-Induced Obese Mice
Kuipers, Eline N., Dam, Andrea D. van, Held, Ntsiki M., Mol, Isabel M., Houtkooper, Riekelt H., Rensen, Patrick C.N., Boon, Mariëtte R.
Published in International journal of molecular sciences (16.06.2018)
Published in International journal of molecular sciences (16.06.2018)
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Journal Article
Selective Glucocorticoid Receptor Modulation Prevents and Reverses Nonalcoholic Fatty Liver Disease in Male Mice
Koorneef, Lisa L, van den Heuvel, José K, Kroon, Jan, Boon, Mariëtte R, 't Hoen, Peter A C, Hettne, Kristina M, van de Velde, Nienke M, Kolenbrander, Kelsey B, Streefland, Trea C M, Mol, Isabel M, Sips, Hetty C M, Kielbasa, Szymon M, Mei, Hailiang, Belanoff, Joseph K, Pereira, Alberto M, Oosterveer, Maaike H, Hunt, Hazel, Rensen, Patrick C N, Meijer, Onno C
Published in Endocrinology (Philadelphia) (01.12.2018)
Published in Endocrinology (Philadelphia) (01.12.2018)
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Journal Article
A Diurnal Rhythm in Brown Adipose Tissue Causes Rapid Clearance and Combustion of Plasma Lipids at Wakening
van den Berg, Rosa, Kooijman, Sander, Noordam, Raymond, Ramkisoensing, Ashna, Abreu-Vieira, Gustavo, Tambyrajah, Lauren L., Dijk, Wieneke, Ruppert, Philip, Mol, Isabel M., Kramar, Barbara, Caputo, Rosanna, Puig, Laura Sardón, de Ruiter, Evelien M., Kroon, Jan, Hoekstra, Menno, van der Sluis, Ronald J., Meijer, Onno C., Willems van Dijk, Ko, van Kerkhof, Linda W.M., Christodoulides, Constantinos, Karpe, Fredrik, Gerhart-Hines, Zachary, Kersten, Sander, Meijer, Johanna H., Coomans, Claudia P., van Heemst, Diana, Biermasz, Nienke R., Rensen, Patrick C.N.
Published in Cell reports (Cambridge) (27.03.2018)
Published in Cell reports (Cambridge) (27.03.2018)
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Journal Article
Identification of mineralocorticoid receptor target genes in the mouse hippocampus
van Weert, Lisa T. C. M., Buurstede, Jacobus C., Sips, Hetty C. M., Vettorazzi, Sabine, Mol, Isabel M., Hartmann, Jakob, Prekovic, Stefan, Zwart, Wilbert, Schmidt, Mathias V., Roozendaal, Benno, Tuckermann, Jan P., Sarabdjitsingh, R. Angela, Meijer, Onno C.
Published in Journal of neuroendocrinology (01.08.2019)
Published in Journal of neuroendocrinology (01.08.2019)
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Journal Article
A Mixed Glucocorticoid/Mineralocorticoid Selective Modulator With Dominant Antagonism in the Male Rat Brain
Atucha, Erika, Zalachoras, Ioannis, van den Heuvel, José K., van Weert, Lisa T. C. M., Melchers, Diana, Mol, Isabel M., Belanoff, Joseph K., Houtman, René, Hunt, Hazel, Roozendaal, Benno, Meijer, Onno C.
Published in Endocrinology (Philadelphia) (01.11.2015)
Published in Endocrinology (Philadelphia) (01.11.2015)
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Journal Article
Mechanistic Insights in NeuroD Potentiation of Mineralocorticoid Receptor Signaling
van Weert, Lisa T. C. M., Buurstede, Jacobus C., Sips, Hetty C. M., Mol, Isabel M., Puri, Tanvi, Damsteegt, Ruth, Roozendaal, Benno, Sarabdjitsingh, R. Angela, Meijer, Onno C.
Published in International journal of molecular sciences (29.03.2019)
Published in International journal of molecular sciences (29.03.2019)
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Journal Article
Chronic infusion of taurolithocholate into the brain increases fat oxidation in mice
Eggink, Hannah M, Tambyrajah, Lauren L, van den Berg, Rosa, Mol, Isabel M, van den Heuvel, Jose K, Koehorst, Martijn, Groen, Albert K, Boelen, Anita, Kalsbeek, Andries, Romijn, Johannes A, Rensen, Patrick C N, Kooijman, Sander, Soeters, Maarten R
Published in Journal of endocrinology (01.02.2018)
Published in Journal of endocrinology (01.02.2018)
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Journal Article
Deletion of hematopoietic Dectin-2 or CARD9 does not protect against atherosclerotic plaque formation in hyperlipidemic mice
Thiem, Kathrin, Hoeke, Geerte, van den Berg, Susan, Hijmans, Anneke, Jacobs, Cor W. M., Zhou, Enchen, Mol, Isabel M., Mouktaroudi, Maria, Bussink, Johan, Kanneganti, Thirumala D., Lutgens, Esther, Stienstra, Rinke, Tack, Cees J., Netea, Mihai G., Rensen, Patrick C. N., Berbée, Jimmy F. P., van Diepen, Janna A.
Published in Scientific reports (13.03.2019)
Published in Scientific reports (13.03.2019)
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Journal Article
Resveratrol protects against atherosclerosis, but does not add to the antiatherogenic effect of atorvastatin, in APOE3-Leiden.CETP mice
Berbée, Jimmy F.P, Wong, Man C, Wang, Yanan, van der Hoorn, José W.A, Khedoe, Padmini P.S.J, van Klinken, Jan B, Mol, Isabel M, Hiemstra, Pieter S, Tsikas, Dimitrios, Romijn, Johannes A, Havekes, Louis M, Princen, Hans M.G, Rensen, Patrick C.N
Published in The Journal of nutritional biochemistry (01.08.2013)
Published in The Journal of nutritional biochemistry (01.08.2013)
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Journal Article