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Trifluridine–Tipiracil and Bevacizumab in Refractory Metastatic Colorectal Cancer
Prager, Gerald W., Taieb, Julien, Fakih, Marwan, Ciardiello, Fortunato, Van Cutsem, Eric, Elez, Elena, Cruz, Felipe M., Wyrwicz, Lucjan, Stroyakovskiy, Daniil, Pápai, Zsuzsanna, Poureau, Pierre-Guillaume, Liposits, Gabor, Cremolini, Chiara, Bondarenko, Igor, Modest, Dominik P., Benhadji, Karim A., Amellal, Nadia, Leger, Catherine, Vidot, Loïck, Tabernero, Josep
Published in The New England journal of medicine (04.05.2023)
Published in The New England journal of medicine (04.05.2023)
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Journal Article
FOLFOXIRI Plus Panitumumab As First-Line Treatment of RAS Wild-Type Metastatic Colorectal Cancer: The Randomized, Open-Label, Phase II VOLFI Study (AIO KRK0109)
Modest, Dominik P., Martens, Uwe M., Riera-Knorrenschild, Jorge, Greeve, Jobst, Florschütz, Axel, Wessendorf, Swen, Ettrich, Thomas, Kanzler, Stephan, Nörenberg, Dominik, Ricke, Jens, Seidensticker, Max, Held, Swantje, Buechner-Steudel, Petra, Atzpodien, Jens, Heinemann, Volker, Seufferlein, Thomas, Tannapfel, Andrea, Reinacher-Schick, Anke C., Geissler, Michael
Published in Journal of clinical oncology (10.12.2019)
Published in Journal of clinical oncology (10.12.2019)
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Journal Article
FOLFIRI plus cetuximab versus FOLFIRI plus bevacizumab for metastatic colorectal cancer (FIRE-3): a post-hoc analysis of tumour dynamics in the final RAS wild-type subgroup of this randomised open-label phase 3 trial
Stintzing, Sebastian, Modest, Dominik P, Rossius, Lisa, Lerch, Markus M, von Weikersthal, Ludwig Fischer, Decker, Thomas, Kiani, Alexander, Vehling-Kaiser, Ursula, Al-Batran, Salah-Eddin, Heintges, Tobias, Lerchenmüller, Christian, Kahl, Christoph, Seipelt, Gernot, Kullmann, Frank, Stauch, Martina, Scheithauer, Werner, Held, Swantje, Giessen-Jung, Clemens, Moehler, Markus, Jagenburg, Andreas, Kirchner, Thomas, Jung, Andreas, Heinemann, Volker
Published in The lancet oncology (01.10.2016)
Published in The lancet oncology (01.10.2016)
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Journal Article
NeoRAS wild-type in metastatic colorectal cancer: Myth or truth?—Case series and review of the literature
Osumi, Hiroki, Vecchione, Loredana, Keilholz, Ulrich, Vollbrecht, Claudia, Alig, Annabel H.S., von Einem, Jobst C., Stahler, Arndt, Striefler, Jana K., Kurreck, Annika, Kind, Andreas, Modest, Dominik P., Stintzing, Sebastian, Jelas, Ivan
Published in European journal of cancer (1990) (01.08.2021)
Published in European journal of cancer (1990) (01.08.2021)
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Journal Article
Is interval chemotherapy safe and does it improve the outcome of patients with colorectal liver metastases undergoing multimodal two-stage hepatectomy? – A systematic literature review
Raschzok, Nathanael, Moosburner, Simon, Blank, Moritz, Krenzien, Felix, Lurje, Georg, Schöning, Wenzel, Sauer, Igor M., Pratschke, Johann, Modest, Dominik P., Kurreck, Annika
Published in BMC cancer (10.10.2024)
Published in BMC cancer (10.10.2024)
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Journal Article
Correction: Is interval chemotherapy safe and does it improve the outcome of patients with colorectal liver metastases undergoing multimodal two-stage hepatectomy? – A systematic literature review
Raschzok, Nathanael, Moosburner, Simon, Blank, Moritz, Krenzien, Felix, Lurje, Georg, Schöning, Wenzel, Sauer, Igor M., Pratschke, Johann, Modest, Dominik P., Kurreck, Annika
Published in BMC cancer (11.11.2024)
Published in BMC cancer (11.11.2024)
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Journal Article
Management, risk factors and prognostic impact of checkpoint-inhibitor pneumonitis (CIP) in lung cancer – A multicenter observational analysis
Frost, Nikolaj, Unger, Kristina, Blum, Torsten Gerriet, Misch, Daniel, Kurz, Sylke, Lüders, Heike, Olive, Elisabeth, Raspe, Matthias, Hilbrandt, Moritz, Koch, Myriam, Böhmer, Dirk, Senger, Carolin, Witzenrath, Martin, Grohé, Christian, Bauer, Torsten, Modest, Dominik P., Kollmeier, Jens
Published in Lung cancer (Amsterdam, Netherlands) (01.05.2023)
Published in Lung cancer (Amsterdam, Netherlands) (01.05.2023)
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Journal Article
The Oncology Biomarker Discovery framework reveals cetuximab and bevacizumab response patterns in metastatic colorectal cancer
Ohnmacht, Alexander J., Stahler, Arndt, Stintzing, Sebastian, Modest, Dominik P., Holch, Julian W., Westphalen, C. Benedikt, Hölzel, Linus, Schübel, Marisa K., Galhoz, Ana, Farnoud, Ali, Ud-Dean, Minhaz, Vehling-Kaiser, Ursula, Decker, Thomas, Moehler, Markus, Heinig, Matthias, Heinemann, Volker, Menden, Michael P.
Published in Nature Communications (04.09.2023)
Published in Nature Communications (04.09.2023)
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Journal Article
Prognostic value of CA 19-9, CEA, CRP, LDH and bilirubin levels in locally advanced and metastatic pancreatic cancer: results from a multicenter, pooled analysis of patients receiving palliative chemotherapy
Haas, Michael, Heinemann, Volker, Kullmann, Frank, Laubender, Rüdiger P., Klose, Christina, Bruns, Christiane J., Holdenrieder, Stefan, Modest, Dominik P., Schulz, Christoph, Boeck, Stefan
Published in Journal of cancer research and clinical oncology (01.04.2013)
Published in Journal of cancer research and clinical oncology (01.04.2013)
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Journal Article
Study protocol of an open-label, single arm phase II trial investigating the efficacy and safety of Trifluridine/Tipiracil combined with irinotecan as a second line therapy in patients with cholangiocarcinoma (TRITICC)
Kehmann, Linde, Berres, Marie-Luise, Gonzalez-Carmona, Maria, Modest, Dominik P., Mohr, Raphael, Wree, Alexander, Venerito, Marino, Strassburg, Christian, Keitel, Verena, Trautwein, Christian, Luedde, Tom, Roderburg, Christoph
Published in BMC cancer (22.05.2023)
Published in BMC cancer (22.05.2023)
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Journal Article
Standard diametric versus volumetric early tumor shrinkage as a predictor of survival in metastatic colorectal cancer: subgroup findings of the randomized, open-label phase III trial FIRE-3 / AIO KRK-0306
Hofmann, Felix O., Heinemann, Volker, D’Anastasi, Melvin, Gesenhues, Alena B., Hesse, Nina, von Weikersthal, Ludwig Fischer, Decker, Thomas, Kiani, Alexander, Moehler, Markus, Kaiser, Florian, Heintges, Tobias, Kahl, Christoph, Kullmann, Frank, Scheithauer, Werner, Link, Hartmut, Modest, Dominik P., Stintzing, Sebastian, Holch, Julian W.
Published in European Radiology (01.02.2023)
Published in European Radiology (01.02.2023)
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Journal Article
Evaluation of circulating tumor DNA as a prognostic and predictive biomarker in BRAF V600E mutated colorectal cancer—results from the FIRE‐4.5 study
Klein‐Scory, Susanne, Baraniskin, Alexander, Schmiegel, Wolff, Mika, Thomas, Schroers, Roland, Held, Swantje, Heinrich, Kathrin, Tougeron, David, Modest, Dominik P., Schwaner, Ingo, Eucker, Jan, Pihusch, Rudolf, Stauch, Martina, Kaiser, Florian, Kahl, Christoph, Karthaus, Meinolf, Müller, Christian, Burkart, Christof, Stintzing, Sebastian, Heinemann, Volker
Published in Molecular oncology (01.02.2025)
Published in Molecular oncology (01.02.2025)
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Journal Article
Early tumor shrinkage in metastatic colorectal cancer: Retrospective analysis from an irinotecan‐based randomized first‐line trial
Giessen, Clemens, Laubender, Ruediger P., Fischer von Weikersthal, Ludwig, Schalhorn, Andreas, Modest, Dominik P., Stintzing, Sebastian, Haas, Michael, Mansmann, Ulrich R., Heinemann, Volker
Published in Cancer science (01.06.2013)
Published in Cancer science (01.06.2013)
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Journal Article
KRAS mutation status is not predictive for objective response to anti-EGFR treatment with erlotinib in patients with advanced pancreatic cancer
Boeck, Stefan, Jung, Andreas, Laubender, Rüdiger P., Neumann, Jens, Egg, Rosalind, Goritschan, Clara, Ormanns, Steffen, Haas, Michael, Modest, Dominik P., Kirchner, Thomas, Heinemann, Volker
Published in Journal of gastroenterology (01.04.2013)
Published in Journal of gastroenterology (01.04.2013)
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Journal Article
Clinical prognosticators and targets in the immune microenvironment of intrahepatic cholangiocarcinoma
Lozzi, Isis, Arnold, Alexander, Barone, Matthias, Johnson, Juliette Claire, Sinn, Bruno V, Eschrich, Johannes, Gebert, Pimrapat, Wang, Ruonan, Hu, Mengwen, Feldbrügge, Linda, Schirmeier, Anja, Reutzel-Selke, Anja, Malinka, Thomas, Krenzien, Felix, Schöning, Wenzel, Modest, Dominik P, Pratschke, Johann, Sauer, Igor M, Felsenstein, Matthäus
Published in Oncoimmunology (31.12.2024)
Published in Oncoimmunology (31.12.2024)
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Journal Article
Radiotherapeutic treatment options for oligotopic malignant liver lesions
Wust, Peter, Beck, Marcus, Dabrowski, Robert, Neumann, Oliver, Zschaeck, Sebastian, Kaul, David, Modest, Dominik P., Stromberger, Carmen, Gebauer, Bernhard, Ghadjar, Pirus
Published in Radiation oncology (London, England) (16.03.2021)
Published in Radiation oncology (London, England) (16.03.2021)
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Journal Article
FIRE-9 – PORT / AIO-KRK-0418: a prospective, randomized, open, multicenter Phase III trial to investigate the efficacy of adjuvant/additive chemotherapy in patients with definitely-treated metastatic colorectal cancer
Raschzok, Nathanael, Stintzing, Sebastian, Heinemann, Volker, Rauch, Geraldine, Ricke, Jens, Guckenberger, Matthias, Kurreck, Annika, Alig, Annabel H. S., Stahler, Arndt, Bullinger, Lars, Schmelzle, Moritz, Schöning, Wenzel, Lurje, Georg, Krenzien, Felix, Haase, Oliver, Rau, Beate, Gebauer, Bernhard, Sauer, Igor M., Pratschke, Johann, Modest, Dominik P.
Published in BMC cancer (02.04.2022)
Published in BMC cancer (02.04.2022)
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Journal Article
Relation of early tumor shrinkage (ETS) observed in first‐line treatment to efficacy parameters of subsequent treatment in FIRE‐3 (AIOKRK0306)
Modest, Dominik P., Stintzing, Sebastian, Fischer von Weikersthal, Ludwig, Decker, Thomas, Kiani, Alexander, Vehling‐Kaiser, Ursula, Al‐Batran, Salah‐Eddin, Heintges, Tobias, Lerchenmüller, Christian, Kahl, Christoph, Seipelt, Gernot, Kullmann, Frank, Scheithauer, Werner, Kirchner, Thomas, Jung, Andreas, Stauch, Martina, von Einem, Jobst Christian, Moehler, Markus, Held, Swantje, Heinemann, Volker
Published in International journal of cancer (15.04.2017)
Published in International journal of cancer (15.04.2017)
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Journal Article
Response and Disease Dynamics in Untreated Metastatic Colorectal Cancer With Bevacizumab-Based Sequential vs. Combination Chemotherapy—Analysis of the Phase 3 XELAVIRI Trial
Kurreck, Annika, Heinemann, Volker, Fischer von Weikersthal, Ludwig, Decker, Thomas, Kaiser, Florian, Uhlig, Jens, Schenk, Michael, Freiberg-Richter, Jens, Peuser, Bettina, Denzlinger, Claudio, Graeven, Ullrich, Heinrich, Kathrin, Held, Swantje, Stahler, Arndt, Alig, Annabel Helga Sophie, Jelas, Ivan, von Einem, Jobst C., Stintzing, Sebastian, Giessen-Jung, Clemens, Modest, Dominik P.
Published in Frontiers in oncology (18.02.2022)
Published in Frontiers in oncology (18.02.2022)
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Journal Article
Sotorasib plus Panitumumab in Refractory Colorectal Cancer with Mutated KRAS G12C
Fakih, Marwan G, Salvatore, Lisa, Esaki, Taito, Modest, Dominik P, Lopez-Bravo, David P, Taieb, Julien, Karamouzis, Michalis V, Ruiz-Garcia, Erika, Kim, Tae-Won, Kuboki, Yasutoshi, Meriggi, Fausto, Cunningham, David, Yeh, Kun-Huei, Chan, Emily, Chao, Joseph, Saportas, Yaneth, Tran, Qui, Cremolini, Chiara, Pietrantonio, Filippo
Published in New England Journal of Medicine (07.12.2023)
Published in New England Journal of Medicine (07.12.2023)
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Journal Article