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Identification of Regulatory Networks in HSCs and Their Immediate Progeny via Integrated Proteome, Transcriptome, and DNA Methylome Analysis
Cabezas-Wallscheid, Nina, Klimmeck, Daniel, Hansson, Jenny, Lipka, Daniel B., Reyes, Alejandro, Wang, Qi, Weichenhan, Dieter, Lier, Amelie, von Paleske, Lisa, Renders, Simon, Wünsche, Peer, Zeisberger, Petra, Brocks, David, Gu, Lei, Herrmann, Carl, Haas, Simon, Essers, Marieke A.G., Brors, Benedikt, Eils, Roland, Huber, Wolfgang, Milsom, Michael D., Plass, Christoph, Krijgsveld, Jeroen, Trumpp, Andreas
Published in Cell stem cell (02.10.2014)
Published in Cell stem cell (02.10.2014)
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Journal Article
Inflammation-Induced Emergency Megakaryopoiesis Driven by Hematopoietic Stem Cell-like Megakaryocyte Progenitors
Haas, Simon, Hansson, Jenny, Klimmeck, Daniel, Loeffler, Dirk, Velten, Lars, Uckelmann, Hannah, Wurzer, Stephan, Prendergast, Áine M., Schnell, Alexandra, Hexel, Klaus, Santarella-Mellwig, Rachel, Blaszkiewicz, Sandra, Kuck, Andrea, Geiger, Hartmut, Milsom, Michael D., Steinmetz, Lars M., Schroeder, Timm, Trumpp, Andreas, Krijgsveld, Jeroen, Essers, Marieke A.G.
Published in Cell stem cell (01.10.2015)
Published in Cell stem cell (01.10.2015)
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Journal Article
The GAPDH redox switch safeguards reductive capacity and enables survival of stressed tumour cells
Talwar, Deepti, Miller, Colin G., Grossmann, Justus, Szyrwiel, Lukasz, Schwecke, Torsten, Demichev, Vadim, Mikecin Drazic, Ana-Matea, Mayakonda, Anand, Lutsik, Pavlo, Veith, Carmen, Milsom, Michael D., Müller-Decker, Karin, Mülleder, Michael, Ralser, Markus, Dick, Tobias P.
Published in Nature metabolism (01.04.2023)
Published in Nature metabolism (01.04.2023)
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Journal Article
Requirement for CDK6 in MLL-rearranged acute myeloid leukemia
Placke, Theresa, Faber, Katrin, Nonami, Atsushi, Putwain, Sarah L., Salih, Helmut R., Heidel, Florian H., Krämer, Alwin, Root, David E., Barbie, David A., Krivtsov, Andrei V., Armstrong, Scott A., Hahn, William C., Huntly, Brian J., Sykes, Stephen M., Milsom, Michael D., Scholl, Claudia, Fröhling, Stefan
Published in Blood (03.07.2014)
Published in Blood (03.07.2014)
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Journal Article
Continuous mitotic activity of primitive hematopoietic stem cells in adult mice
Morcos, Mina N.F., Zerjatke, Thomas, Glauche, Ingmar, Munz, Clara M., Ge, Yan, Petzold, Andreas, Reinhardt, Susanne, Dahl, Andreas, Anstee, Natasha S., Bogeska, Ruzhica, Milsom, Michael D., Säwén, Petter, Wan, Haixia, Bryder, David, Roers, Axel, Gerbaulet, Alexander
Published in The Journal of experimental medicine (01.06.2020)
Published in The Journal of experimental medicine (01.06.2020)
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Journal Article
A 3D iPSC-differentiation model identifies interleukin-3 as a regulator of early human hematopoietic specification
Ackermann, Mania, Haake, Kathrin, Kempf, Henning, Kaschutnig, Paul, Weiss, Anna-Carina, Nguyen, Ariane H H, Abeln, Markus, Merkert, Sylvia, Kühnel, Mark Phillip, Hartmann, Dorothee, Jonigk, Danny, Thum, Thomas, Kispert, Andreas, Milsom, Michael D, Lachmann, Nico
Published in Haematologica (Roma) (01.05.2021)
Published in Haematologica (Roma) (01.05.2021)
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Journal Article
Influenza A virus infection instructs hematopoiesis to megakaryocyte-lineage output
Rommel, Marcel G.E., Walz, Lisa, Fotopoulou, Foteini, Kohlscheen, Saskia, Schenk, Franziska, Miskey, Csaba, Botezatu, Lacramioara, Krebs, Yvonne, Voelker, Iris M., Wittwer, Kevin, Holland-Letz, Tim, Ivics, Zoltán, von Messling, Veronika, Essers, Marieke A.G., Milsom, Michael D., Pfaller, Christian K., Modlich, Ute
Published in Cell reports (Cambridge) (04.10.2022)
Published in Cell reports (Cambridge) (04.10.2022)
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Journal Article
Overcoming reprogramming resistance of Fanconi anemia cells
Müller, Lars U.W., Milsom, Michael D., Harris, Chad E., Vyas, Rutesh, Brumme, Kristina M., Parmar, Kalindi, Moreau, Lisa A., Schambach, Axel, Park, In-Hyun, London, Wendy B., Strait, Kelly, Schlaeger, Thorsten, DeVine, Alexander L., Grassman, Elke, D'Andrea, Alan, Daley, George Q., Williams, David A.
Published in Blood (07.06.2012)
Published in Blood (07.06.2012)
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Journal Article
EDA-Fibronectin Originating from Osteoblasts Inhibits the Immune Response against Cancer
Rossnagl, Stephanie, Altrock, Eva, Sens, Carla, Kraft, Sabrina, Rau, Katrin, Milsom, Michael D., Giese, Thomas, Samstag, Yvonne, Nakchbandi, Inaam A.
Published in PLoS biology (21.09.2016)
Published in PLoS biology (21.09.2016)
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Journal Article
Stem Cell-Specific Mechanisms Ensure Genomic Fidelity within HSCs and upon Aging of HSCs
Moehrle, Bettina M., Nattamai, Kalpana, Brown, Andreas, Florian, Maria C., Ryan, Marnie, Vogel, Mona, Bliederhaeuser, Corinna, Soller, Karin, Prows, Daniel R., Abdollahi, Amir, Schleimer, David, Walter, Dagmar, Milsom, Michael D., Stambrook, Peter, Porteus, Matthew, Geiger, Hartmut
Published in Cell reports (Cambridge) (22.12.2015)
Published in Cell reports (Cambridge) (22.12.2015)
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Journal Article
Hotspot DNMT3A mutations in clonal hematopoiesis and acute myeloid leukemia sensitize cells to azacytidine via viral mimicry response
Scheller, Marina, Ludwig, Anne Kathrin, Göllner, Stefanie, Rohde, Christian, Krämer, Stephen, Stäble, Sina, Janssen, Maike, Müller, James-Arne, He, Lixiazi, Bäumer, Nicole, Arnold, Christian, Gerß, Joachim, Schönung, Maximilian, Thiede, Christian, Niederwieser, Christian, Niederwieser, Dietger, Serve, Hubert, Berdel, Wolfgang E, Thiem, Ulrich, Hemmerling, Inga, Leuschner, Florian, Plass, Christoph, Schlesner, Matthias, Zaugg, Judith, Milsom, Michael D, Trumpp, Andreas, Pabst, Caroline, Lipka, Daniel B, Müller-Tidow, Carsten
Published in Nature cancer (01.05.2021)
Published in Nature cancer (01.05.2021)
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Journal Article
Protein Kinase C Epsilon Is a Key Regulator of Mitochondrial Redox Homeostasis in Acute Myeloid Leukemia
Di Marcantonio, Daniela, Martinez, Esteban, Sidoli, Simone, Vadaketh, Jessica, Nieborowska-Skorska, Margaret, Gupta, Anushk, Meadows, Jake M., Ferraro, Francesca, Masselli, Elena, Challen, Grant A., Milsom, Michael D., Scholl, Claudia, Fröhling, Stefan, Balachandran, Siddharth, Skorski, Tomasz, Garcia, Benjamin A., Mirandola, Prisco, Gobbi, Giuliana, Garzon, Ramiro, Vitale, Marco, Sykes, Stephen M.
Published in Clinical cancer research (01.02.2018)
Published in Clinical cancer research (01.02.2018)
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Journal Article
The Fanconi anemia pathway is required for efficient repair of stress-induced DNA damage in haematopoietic stem cells
Kaschutnig, Paul, Bogeska, Ruzhica, Walter, Dagmar, Lier, Amelie, Huntscha, Sina, Milsom, Michael D
Published in Cell cycle (Georgetown, Tex.) (02.09.2015)
Published in Cell cycle (Georgetown, Tex.) (02.09.2015)
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Journal Article