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In Silico Study Identified Methotrexate Analog as Potential Inhibitor of Drug Resistant Human Dihydrofolate Reductase for Cancer Therapeutics
Rana, Rabia Mukhtar, Rampogu, Shailima, Abid, Noman Bin, Zeb, Amir, Parate, Shraddha, Lee, Gihwan, Yoon, Sanghwa, Kim, Yumi, Kim, Donghwan, Lee, Keun Woo
Published in Molecules (Basel, Switzerland) (31.07.2020)
Published in Molecules (Basel, Switzerland) (31.07.2020)
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Journal Article
Dihydrofolate Reductase Deficiency Due to a Homozygous DHFR Mutation Causes Megaloblastic Anemia and Cerebral Folate Deficiency Leading to Severe Neurologic Disease
Cario, Holger, Smith, Desirée E.C., Blom, Henk, Blau, Nenad, Bode, Harald, Holzmann, Karlheinz, Pannicke, Ulrich, Hopfner, Karl-Peter, Rump, Eva-Maria, Ayric, Zuleya, Kohne, Elisabeth, Debatin, Klaus-Michael, Smulders, Yvo, Schwarz, Klaus
Published in American journal of human genetics (11.02.2011)
Published in American journal of human genetics (11.02.2011)
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Journal Article
Analysis of methotrexate and folate transport by multidrug resistance protein 4 (ABCC4): MRP4 is a component of the methotrexate efflux system
CHEN, Zhe-Sheng, LEE, Kun, WALTHER, Susan, RAFTOGIANIS, Rebecca Blanchard, KUWANO, Michihiko, HAO ZENG, KRUH, Gary D
Published in Cancer research (Chicago, Ill.) (01.06.2002)
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Published in Cancer research (Chicago, Ill.) (01.06.2002)
Journal Article
Transport of methotrexate (MTX) and folates by multidrug resistance protein (MRP) 3 and MRP1: Effect of polyglutamylation on MTX transport
HAO ZENG, CHEN, Zhe-Sheng, BELINSKY, Martin G, REA, Philip A, KRUH, Gary D
Published in Cancer research (Chicago, Ill.) (01.10.2001)
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Published in Cancer research (Chicago, Ill.) (01.10.2001)
Journal Article
The antileukemic activity of modified fibrinogen–methotrexate conjugate
Goszczyński, Tomasz, Nevozhay, Dmitry, Wietrzyk, Joanna, Omar, Mohamed Salah, Boratyński, Janusz
Published in Biochimica et biophysica acta (01.03.2013)
Published in Biochimica et biophysica acta (01.03.2013)
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Journal Article
Pharmacokinetics and pharmacodynamics of low‐dose methotrexate in the treatment of psoriasis
Chládek, Jaroslav, Grim, Jiøı´, Martínková, Jiøina, Šimková, Marie, Vanı`èková, Jaroslava, Koudelková, Vı`ra, Noièková, Marie
Published in British journal of clinical pharmacology (01.08.2002)
Published in British journal of clinical pharmacology (01.08.2002)
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Journal Article
Transport of methotrexate, methotrexate polyglutamates, and 17beta-estradiol 17-(beta-D-glucuronide) by ABCG2: effects of acquired mutations at R482 on methotrexate transport
Chen, Zhe-Sheng, Robey, Robert W, Belinsky, Martin G, Shchaveleva, Irina, Ren, Xiao-Qin, Sugimoto, Yoshikazu, Ross, Douglas D, Bates, Susan E, Kruh, Gary D
Published in Cancer research (Chicago, Ill.) (15.07.2003)
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Published in Cancer research (Chicago, Ill.) (15.07.2003)
Journal Article
Continuous intratumoral microdialysis during high-dose methotrexate therapy in a patient with malignant fibrous histiocytoma of the femur: a case report
Ekstrøm, Per O., Andersen, Anders, Saeter, Gunnar, Giercksky, Karl E., Slørdal, L.
Published in Cancer chemotherapy and pharmacology (01.01.1997)
Published in Cancer chemotherapy and pharmacology (01.01.1997)
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Journal Article
In vitro and in vivo biological activities of a novel nonpolyglutamable anti-folate, MX-68
Mihara, Masahiko, Urakawa, Kazumi, Takagi, Nobuhiro, Moriya, Yoichiro, Takeda, Yasuhisa
Published in Immunopharmacology (01.10.1996)
Published in Immunopharmacology (01.10.1996)
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Journal Article