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Single-Cell Profiling Reveals Sex, Lineage, and Regional Diversity in the Mouse Kidney
Ransick, Andrew, Lindström, Nils O., Liu, Jing, Zhu, Qin, Guo, Jin-Jin, Alvarado, Gregory F., Kim, Albert D., Black, Hannah G., Kim, Junhyong, McMahon, Andrew P.
Published in Developmental cell (04.11.2019)
Published in Developmental cell (04.11.2019)
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Journal Article
A scalable organoid model of human autosomal dominant polycystic kidney disease for disease mechanism and drug discovery
Tran, Tracy, Song, Cheng Jack, Nguyen, Trang, Cheng, Shun-Yang, McMahon, Jill A., Yang, Rui, Guo, Qiuyu, Der, Balint, Lindström, Nils O., Lin, Daniel C.-H., McMahon, Andrew P.
Published in Cell stem cell (07.07.2022)
Published in Cell stem cell (07.07.2022)
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Journal Article
Conserved and Divergent Features of Human and Mouse Kidney Organogenesis
Lindström, Nils O., McMahon, Jill A., Guo, Jinjin, Tran, Tracy, Guo, Qiuyu, Rutledge, Elisabeth, Parvez, Riana K., Saribekyan, Gohar, Schuler, Robert E., Liao, Christopher, Kim, Albert D., Abdelhalim, Ahmed, Ruffins, Seth W., Thornton, Matthew E., Basking, Laurence, Grubbs, Brendan, Kesselman, Carl, McMahon, Andrew P.
Published in Journal of the American Society of Nephrology (01.03.2018)
Published in Journal of the American Society of Nephrology (01.03.2018)
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Journal Article
Conserved and Divergent Features of Mesenchymal Progenitor Cell Types within the Cortical Nephrogenic Niche of the Human and Mouse Kidney
Lindström, Nils O., Guo, Jinjin, Kim, Albert D., Tran, Tracy, Guo, Qiuyu, De Sena Brandine, Guilherme, Ransick, Andrew, Parvez, Riana K., Thornton, Matthew E., Basking, Laurence, Grubbs, Brendan, McMahon, Jill A., Smith, Andrew D., McMahon, Andrew P.
Published in Journal of the American Society of Nephrology (01.03.2018)
Published in Journal of the American Society of Nephrology (01.03.2018)
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Journal Article
Progressive Recruitment of Mesenchymal Progenitors Reveals a Time-Dependent Process of Cell Fate Acquisition in Mouse and Human Nephrogenesis
Lindström, Nils O., De Sena Brandine, Guilherme, Tran, Tracy, Ransick, Andrew, Suh, Gio, Guo, Jinjin, Kim, Albert D., Parvez, Riana K., Ruffins, Seth W., Rutledge, Elisabeth A., Thornton, Matthew E., Grubbs, Brendan, McMahon, Jill A., Smith, Andrew D., McMahon, Andrew P.
Published in Developmental cell (04.06.2018)
Published in Developmental cell (04.06.2018)
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Journal Article
In Vivo Developmental Trajectories of Human Podocyte Inform In Vitro Differentiation of Pluripotent Stem Cell-Derived Podocytes
Tran, Tracy, Lindström, Nils O., Ransick, Andrew, De Sena Brandine, Guilherme, Guo, Qiuyu, Kim, Albert D., Der, Balint, Peti-Peterdi, Janos, Smith, Andrew D., Thornton, Matthew, Grubbs, Brendan, McMahon, Jill A., McMahon, Andrew P.
Published in Developmental cell (01.07.2019)
Published in Developmental cell (01.07.2019)
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Journal Article
Axial nephron fate switching demonstrates a plastic system tunable on demand
Achieng, MaryAnne A., Schnell, Jack, Fausto, Connor C., Csipán, Réka L., Koppitch, Kari, Thornton, Matthew E., Grubbs, Brendan H., Lindström, Nils O.
Published in Nature communications (25.08.2025)
Published in Nature communications (25.08.2025)
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Journal Article
Dose-dependent responses to canonical Wnt transcriptional complexes in the regulation of mammalian nephron progenitors
Bugacov, Helena, Der, Balint, Briantseva, Bohdana-Myroslava, Guo, Qiuyu, Kim, Sunghyun, Lindström, Nils O., McMahon, Andrew P.
Published in Development (Cambridge) (15.09.2024)
Published in Development (Cambridge) (15.09.2024)
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Journal Article
Controlling nephron precursor differentiation to generate proximal-biased kidney organoids with emerging maturity
Schnell, Jack, Miao, Zhen, Achieng, MaryAnne, Fausto, Connor C., Koppitch, Kari, Takhirov, Lola, Wang, Victoria, De Kuyper, Faith, Huang, Biao, Schreiber, Megan, Medina, Pedro, Thornton, Matthew E., Grubbs, Brendan, Li, Zhongwei, Kim, Junhyong, Lindström, Nils O.
Published in Nature communications (30.08.2025)
Published in Nature communications (30.08.2025)
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Journal Article
Spatial transcriptional mapping of the human nephrogenic program
Lindström, Nils O., Sealfon, Rachel, Chen, Xi, Parvez, Riana K., Ransick, Andrew, De Sena Brandine, Guilherme, Guo, Jinjin, Hill, Bill, Tran, Tracy, Kim, Albert D., Zhou, Jian, Tadych, Alicja, Watters, Aaron, Wong, Aaron, Lovero, Elizabeth, Grubbs, Brendan H., Thornton, Matthew E., McMahon, Jill A., Smith, Andrew D., Ruffins, Seth W., Armit, Chris, Troyanskaya, Olga G., McMahon, Andrew P.
Published in Developmental cell (23.08.2021)
Published in Developmental cell (23.08.2021)
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Journal Article
Long-term expandable mouse and human-induced nephron progenitor cells enable kidney organoid maturation and modeling of plasticity and disease
Huang, Biao, Zeng, Zipeng, Kim, Sunghyun, Fausto, Connor C., Koppitch, Kari, Li, Hui, Li, Zexu, Chen, Xi, Guo, Jinjin, Zhang, Chennan C., Ma, Tianyi, Medina, Pedro, Schreiber, Megan E., Xia, Mateo W., Vonk, Ariel C., Xiang, Tianyuan, Patel, Tadrushi, Li, Yidan, Parvez, Riana K., Der, Balint, Chen, Jyun Hao, Liu, Zhenqing, Thornton, Matthew E., Grubbs, Brendan H., Diao, Yarui, Dou, Yali, Gnedeva, Ksenia, Ying, Qilong, Pastor-Soler, Nuria M., Fei, Teng, Hallows, Kenneth R., Lindström, Nils O., McMahon, Andrew P., Li, Zhongwei
Published in Cell stem cell (06.06.2024)
Published in Cell stem cell (06.06.2024)
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Journal Article
Single-Cell RNA Sequencing of the Adult Mouse Kidney: From Molecular Cataloging of Cell Types to Disease-Associated Predictions
Lindström, Nils O., De Sena Brandine, Guilherme, Ransick, Andrew, McMahon, Andrew P.
Published in American journal of kidney diseases (01.01.2019)
Published in American journal of kidney diseases (01.01.2019)
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Journal Article
Wnt11 directs nephron progenitor polarity and motile behavior ultimately determining nephron endowment
O'Brien, Lori L, Combes, Alexander N, Short, Kieran M, Lindström, Nils O, Whitney, Peter H, Cullen-McEwen, Luise A, Ju, Adler, Abdelhalim, Ahmed, Michos, Odyssé, Bertram, John F, Smyth, Ian M, Little, Melissa H, McMahon, Andrew P
Published in eLife (05.12.2018)
Published in eLife (05.12.2018)
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Journal Article
Integrated β-catenin, BMP, PTEN, and Notch signalling patterns the nephron
Lindström, Nils O, Lawrence, Melanie L, Burn, Sally F, Johansson, Jeanette A, Bakker, Elvira RM, Ridgway, Rachel A, Chang, C-Hong, Karolak, Michele J, Oxburgh, Leif, Headon, Denis J, Sansom, Owen J, Smits, Ron, Davies, Jamie A, Hohenstein, Peter
Published in eLife (03.02.2015)
Published in eLife (03.02.2015)
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Journal Article
Nephrons require Rho-kinase for proximal-distal polarity development
Lindström, Nils O., Hohenstein, Peter, Davies, Jamie A.
Published in Scientific reports (18.09.2013)
Published in Scientific reports (18.09.2013)
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Journal Article
Deducing the stage of origin of Wilms' tumours from a developmental series of Wt1-mutant mice
Berry, Rachel L, Ozdemir, Derya D, Aronow, Bruce, Lindström, Nils O, Dudnakova, Tatiana, Thornburn, Anna, Perry, Paul, Baldock, Richard, Armit, Chris, Joshi, Anagha, Jeanpierre, Cécile, Shan, Jingdong, Vainio, Seppo, Baily, James, Brownstein, David, Davies, Jamie, Hastie, Nicholas D, Hohenstein, Peter
Published in Disease models & mechanisms (01.08.2015)
Published in Disease models & mechanisms (01.08.2015)
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Journal Article
Conserved and Divergent Molecular and Anatomic Features of Human and Mouse Nephron Patterning
Lindström, Nils O., Tran, Tracy, Guo, Jinjin, Rutledge, Elisabeth, Parvez, Riana K., Thornton, Matthew E., Grubbs, Brendan, McMahon, Jill A., McMahon, Andrew P.
Published in Journal of the American Society of Nephrology (01.03.2018)
Published in Journal of the American Society of Nephrology (01.03.2018)
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Journal Article
Dact2 is expressed in the developing ureteric bud/collecting duct system of the kidney and controls morphogenetic behavior of collecting duct cells
Lee, Wen-Chin, Hough, Melinda T., Liu, Weijia, Ekiert, Robert, Lindström, Nils O., Hohenstein, Peter, Davies, Jamie A.
Published in American journal of physiology. Renal physiology (01.10.2010)
Published in American journal of physiology. Renal physiology (01.10.2010)
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Journal Article