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A Unique Gene Regulatory Network Resets the Human Germline Epigenome for Development
Tang, Walfred W.C., Dietmann, Sabine, Irie, Naoko, Leitch, Harry G., Floros, Vasileios I., Bradshaw, Charles R., Hackett, Jamie A., Chinnery, Patrick F., Surani, M. Azim
Published in Cell (04.06.2015)
Published in Cell (04.06.2015)
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Journal Article
Defined conditions for propagation and manipulation of mouse embryonic stem cells
Mulas, Carla, Kalkan, Tüzer, von Meyenn, Ferdinand, Leitch, Harry G., Nichols, Jennifer, Smith, Austin
Published in Development (Cambridge) (26.03.2019)
Published in Development (Cambridge) (26.03.2019)
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Journal Article
Different Roles for Tet1 and Tet2 Proteins in Reprogramming-Mediated Erasure of Imprints Induced by EGC Fusion
Piccolo, Francesco M., Bagci, Hakan, Brown, Karen E., Landeira, David, Soza-Ried, Jorge, Feytout, Amelie, Mooijman, Dylan, Hajkova, Petra, Leitch, Harry G., Tada, Takashi, Kriaucionis, Skirmantas, Dawlaty, Meelad M., Jaenisch, Rudolf, Merkenschlager, Matthias, Fisher, Amanda G.
Published in Molecular cell (28.03.2013)
Published in Molecular cell (28.03.2013)
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Journal Article
Primordial germ cell DNA demethylation and development require DNA translesion synthesis
Shah, Pranay, Hill, Ross, Dion, Camille, Clark, Stephen J., Abakir, Abdulkadir, Willems, Jeroen, Arends, Mark J., Garaycoechea, Juan I., Leitch, Harry G., Reik, Wolf, Crossan, Gerry P.
Published in Nature communications (03.05.2024)
Published in Nature communications (03.05.2024)
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Journal Article
Hypogonadotropic hypogonadism in mice lacking a functional Kiss1 gene
d'Anglemont de Tassigny, Xavier, Fagg, Lisa A, Dixon, John P.C, Day, Kate, Leitch, Harry G, Hendrick, Alan G, Zahn, Dirk, Franceschini, Isabelle, Caraty, Alain, Carlton, Mark B.L, Aparicio, Samuel A.J.R, Colledge, William H
Published in Proceedings of the National Academy of Sciences - PNAS (19.06.2007)
Published in Proceedings of the National Academy of Sciences - PNAS (19.06.2007)
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Journal Article
Esrrb Complementation Rescues Development of Nanog-Null Germ Cells
Zhang, Man, Leitch, Harry G., Tang, Walfred W.C., Festuccia, Nicola, Hall-Ponsele, Elisa, Nichols, Jennifer, Surani, M. Azim, Smith, Austin, Chambers, Ian
Published in Cell reports (Cambridge) (09.01.2018)
Published in Cell reports (Cambridge) (09.01.2018)
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Journal Article
Expanding the allelic spectrum of ELOVL4‐related autosomal recessive neuro‐ichthyosis
Alabdulrazzaq, Fatima, Alanzi, Talal, Al‐Balool, Haya H., Gardham, Alice, Wakeling, Emma, Leitch, Harry G., AlSayed, Moeenaldeen, Abdulrahim, Maha, Aladwani, Abdulaziz, Romito, Antonio, Kampe, Kapil, Ferdinandusse, Sacha, Aboelanine, Ashraf H., Abdullah, Amira, Alwadani, Amal, Bastaki, Laila, Vaz, Frédéric M., Bertoli‐Avella, Aida M., Marafi, Dana
Published in Molecular genetics & genomic medicine (01.12.2023)
Published in Molecular genetics & genomic medicine (01.12.2023)
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Journal Article
Primordial Germ-Cell Development and Epigenetic Reprogramming in Mammals
Leitch, Harry G., Tang, Walfred W.C., Surani, M. Azim
Published in Current Topics in Developmental Biology (2013)
Published in Current Topics in Developmental Biology (2013)
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Book Chapter
Journal Article
Rebuilding Pluripotency from Primordial Germ Cells
Leitch, Harry G., Nichols, Jennifer, Humphreys, Peter, Mulas, Carla, Martello, Graziano, Lee, Caroline, Jones, Ken, Surani, M. Azim, Smith, Austin
Published in Stem cell reports (04.06.2013)
Published in Stem cell reports (04.06.2013)
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Journal Article
Reconstitution of the oocyte transcriptional network with transcription factors
Hamazaki, Nobuhiko, Kyogoku, Hirohisa, Araki, Hiromitsu, Miura, Fumihito, Horikawa, Chisako, Hamada, Norio, Shimamoto, So, Hikabe, Orie, Nakashima, Kinichi, Kitajima, Tomoya S., Ito, Takashi, Leitch, Harry G., Hayashi, Katsuhiko
Published in Nature (London) (14.01.2021)
Published in Nature (London) (14.01.2021)
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Journal Article
The Germ Cell Determinant Blimp1 Is Not Required for Derivation of Pluripotent Stem Cells
Bao, Siqin, Leitch, Harry G., Gillich, Astrid, Nichols, Jennifer, Tang, Fuchou, Kim, Shinseog, Lee, Caroline, Zwaka, Thomas, Li, Xihe, Surani, M. Azim
Published in Cell stem cell (06.07.2012)
Published in Cell stem cell (06.07.2012)
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Journal Article
Naive pluripotency is associated with global DNA hypomethylation
Leitch, Harry G, McEwen, Kirsten R, Turp, Aleksandra, Encheva, Vesela, Carroll, Tom, Grabole, Nils, Mansfield, William, Nashun, Buhe, Knezovich, Jaysen G, Smith, Austin, Surani, M Azim, Hajkova, Petra
Published in Nature structural & molecular biology (01.03.2013)
Published in Nature structural & molecular biology (01.03.2013)
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Journal Article
Hallmarks of pluripotency
De Los Angeles, Alejandro, Ferrari, Francesco, Xi, Ruibin, Fujiwara, Yuko, Benvenisty, Nissim, Deng, Hongkui, Hochedlinger, Konrad, Jaenisch, Rudolf, Lee, Soohyun, Leitch, Harry G., Lensch, M. William, Lujan, Ernesto, Pei, Duanqing, Rossant, Janet, Wernig, Marius, Park, Peter J., Daley, George Q.
Published in Nature (London) (24.09.2015)
Published in Nature (London) (24.09.2015)
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Journal Article
Epigenetic Regulation during Primordial Germ Cell Development and Differentiation
Ramakrishna, Navin B., Murison, Keir, Miska, Eric A., Leitch, Harry G.
Published in Sexual development (01.12.2021)
Published in Sexual development (01.12.2021)
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Journal Article