Vyzkoušejte nový nástroj s podporou AI
Summon Research Assistant
BETA
Early pathologic amyloid induces hypersynchrony of BOLD resting-state networks in transgenic mice and provides an early therapeutic window before amyloid plaque deposition
Shah, Disha, Praet, Jelle, Latif Hernandez, Amira, Höfling, Corinna, Anckaerts, Cynthia, Bard, Frédérique, Morawski, Markus, Detrez, Jan R, Prinsen, Els, Villa, Alessandro, De Vos, Winnok H, Maggi, Adriana, D'Hooge, Rudi, Balschun, Detlef, Rossner, Steffen, Verhoye, Marleen, Van der Linden, Annemie
Published in Alzheimer's & dementia (01.09.2016)
Published in Alzheimer's & dementia (01.09.2016)
Get full text
Journal Article
Myeloid deficiency of the intrinsic clock protein BMAL1 accelerates cognitive aging by disrupting microglial synaptic pruning
Iweka, Chinyere Agbaegbu, Seigneur, Erica, Hernandez, Amira Latif, Paredes, Sur Herrera, Cabrera, Mica, Blacher, Eran, Pasternak, Connie Tsai, Longo, Frank M., de Lecea, Luis, Andreasson, Katrin I.
Published in Journal of neuroinflammation (24.02.2023)
Published in Journal of neuroinflammation (24.02.2023)
Get full text
Journal Article
A TrkB and TrkC partial agonist restores deficits in synaptic function and promotes activity‐dependent synaptic and microglial transcriptomic changes in a late‐stage Alzheimer's mouse model
Latif‐Hernandez, Amira, Yang, Tao, Butler, Robert R., Losada, Patricia Moran, Minhas, Paras S., White, Halle, Tran, Kevin C., Liu, Harry, Simmons, Danielle A., Langness, Vanessa, Andreasson, Katrin I., Wyss‐Coray, Tony, Longo, Frank M.
Published in Alzheimer's & dementia (01.07.2024)
Published in Alzheimer's & dementia (01.07.2024)
Get full text
Journal Article
Quinolinic acid injection in mouse medial prefrontal cortex affects reversal learning abilities, cortical connectivity and hippocampal synaptic plasticity
Latif-Hernandez, Amira, Shah, Disha, Ahmed, Tariq, Lo, Adrian C., Callaerts-Vegh, Zsuzsanna, Van der Linden, Annemie, Balschun, Detlef, D’Hooge, Rudi
Published in Scientific reports (07.11.2016)
Published in Scientific reports (07.11.2016)
Get full text
Journal Article
Commentary: APP as a Mediator of the Synapse Pathology in Alzheimer's Disease
Schreurs, An, Latif-Hernandez, Amira, Uwineza, Alice
Published in Frontiers in cellular neuroscience (31.05.2018)
Published in Frontiers in cellular neuroscience (31.05.2018)
Get full text
Journal Article
Subtle behavioral changes and increased prefrontal-hippocampal network synchronicity in APPNL−G−F mice before prominent plaque deposition
Latif-Hernandez, Amira, Shah, Disha, Craessaerts, Kathleen, Saido, Takaomi, Saito, Takashi, De Strooper, Bart, Van der Linden, Annemie, D’Hooge, Rudi
Published in Behavioural brain research (17.05.2019)
Published in Behavioural brain research (17.05.2019)
Get full text
Journal Article
The two faces of synaptic failure in AppNL-G-F knock-in mice
Latif-Hernandez, Amira, Sabanov, Victor, Ahmed, Tariq, Craessaerts, Katleen, Saito, Takashi, Saido, Takaomi, Balschun, Detlef
Published in Alzheimer's Research & Therapy (24.08.2020)
Published in Alzheimer's Research & Therapy (24.08.2020)
Get full text
Journal Article
The two faces of synaptic failure in App NL-G-F knock-in mice
Latif-Hernandez, Amira, Sabanov, Victor, Ahmed, Tariq, Craessaerts, Katleen, Saito, Takashi, Saido, Takaomi, Balschun, Detlef
Published in Alzheimer's research & therapy (24.08.2020)
Published in Alzheimer's research & therapy (24.08.2020)
Get full text
Journal Article
Restoring metabolism of myeloid cells reverses cognitive decline in ageing
Minhas, Paras S., Latif-Hernandez, Amira, McReynolds, Melanie R., Durairaj, Aarooran S., Wang, Qian, Rubin, Amanda, Joshi, Amit U., He, Joy Q., Gauba, Esha, Liu, Ling, Wang, Congcong, Linde, Miles, Sugiura, Yuki, Moon, Peter K., Majeti, Ravi, Suematsu, Makoto, Mochly-Rosen, Daria, Weissman, Irving L., Longo, Frank M., Rabinowitz, Joshua D., Andreasson, Katrin I.
Published in Nature (London) (04.02.2021)
Published in Nature (London) (04.02.2021)
Get full text
Journal Article
Restoring hippocampal glucose metabolism rescues cognition across Alzheimer’s disease pathologies
Minhas, Paras S., Jones, Jeffrey R., Latif-Hernandez, Amira, Sugiura, Yuki, Durairaj, Aarooran S., Wang, Qian, Mhatre, Siddhita D., Uenaka, Takeshi, Crapser, Joshua, Conley, Travis, Ennerfelt, Hannah, Jung, Yoo Jin, Liu, Ling, Prasad, Praveena, Jenkins, Brenita C., Ay, Yeonglong Albert, Matrongolo, Matthew, Goodman, Ryan, Newmeyer, Traci, Heard, Kelly, Kang, Austin, Wilson, Edward N., Yang, Tao, Ullian, Erik M., Serrano, Geidy E., Beach, Thomas G., Wernig, Marius, Rabinowitz, Joshua D., Suematsu, Makoto, Longo, Frank M., McReynolds, Melanie R., Gage, Fred H., Andreasson, Katrin I.
Published in Science (23.08.2024)
Published in Science (23.08.2024)
Get full text
Journal Article
Restoring activity‐dependent synaptic and microglial transcriptomic alterations in late‐stage Alzheimer’s Disease
Latif‐Hernandez, Amira, III, Robert R. Butler, Moran‐Losada, Patricia, Yang, Tao, Tran, Kevin C, Liu, Harry, Wyss‐Coray, Tony, Longo, Frank M.
Published in Alzheimer's & dementia (01.12.2024)
Published in Alzheimer's & dementia (01.12.2024)
Get full text
Journal Article
Spatial reversal learning defect coincides with hypersynchronous telencephalic BOLD functional connectivity in APPNL-F/NL-F knock-in mice
Shah, Disha, Latif-Hernandez, Amira, De Strooper, Bart, Saito, Takashi, Saido, Takaomi, Verhoye, Marleen, D’Hooge, Rudi, Van der Linden, Annemie
Published in Scientific reports (19.04.2018)
Published in Scientific reports (19.04.2018)
Get full text
Journal Article
Neuronal stimulation‐regulated RNA splicing defects in tauopathies are corrected by treatment with a p75 NTR modulator
Latif‐Hernandez, Amira, Moran‐Losada, Patricia, Yang, Tao, White, Halle, Tran, Kevin C, Liu, Harry, Massa, Stephen M., Wyss‐Coray, Tony, Longo, Frank M.
Published in Alzheimer's & dementia (01.12.2023)
Published in Alzheimer's & dementia (01.12.2023)
Get full text
Journal Article
Separate Ionotropic and Metabotropic Glutamate Receptor Functions in Depotentiation vs. LTP: A Distinct Role for Group1 mGluR Subtypes and NMDARs
Latif-Hernandez, Amira, Faldini, Enrico, Ahmed, Tariq, Balschun, Detlef
Published in Frontiers in cellular neuroscience (07.11.2016)
Published in Frontiers in cellular neuroscience (07.11.2016)
Get full text
Journal Article
p75NTR modulation counteracts alterations in neuronal and glial activity‐dependent profiles of gene co‐expression networks in tauopathy mice
Latif‐Hernandez, Amira, Moran‐Losada, Patricia, Yang, Tao, III, Robert R. Butler, Tran, Kevin C, Liu, Harry, Massa, Stephen M., Wyss‐Coray, Tony, Longo, Frank M.
Published in Alzheimer's & dementia (01.12.2022)
Published in Alzheimer's & dementia (01.12.2022)
Get full text
Journal Article
p75 NTR modulation counteracts alterations in neuronal and glial activity‐dependent profiles of gene co‐expression networks in tauopathy mice
Latif‐Hernandez, Amira, Moran‐Losada, Patricia, Yang, Tao, III, Robert R. Butler, Tran, Kevin C, Liu, Harry, Massa, Stephen M., Wyss‐Coray, Tony, Longo, Frank M.
Published in Alzheimer's & dementia (01.12.2022)
Published in Alzheimer's & dementia (01.12.2022)
Get full text
Journal Article
Restoring hippocampal glucose metabolism rescues cognition across Alzheimer disease pathologies
Minhas, Paras S., Jones, Jeffrey R., Latif-Hernandez, Amira, Sugiura, Yuki, Durairaj, Aarooran S., Wang, Qian, Mhatre, Siddhita D., Uenaka, Takeshi, Crapser, Joshua, Conley, Travis, Ennerfelt, Hannah, Jung, Yoo Jin, Liu, Ling, Prasad, Praveena, Jenkins, Brenita C., Ay, Yeonglong Albert, Matrongolo, Matthew, Goodman, Ryan, Newmeyer, Traci, Heard, Kelly, Kang, Austin, Wilson, Edward N., Yang, Tao, Ullian, Erik M., Serrano, Geidy E., Beach, Thomas G., Wernig, Marius, Rabinowitz, Joshua D., Suematsu, Makoto, Longo, Frank M., McReynolds, Melanie R., Gage, Fred H., Andreasson, Katrin I.
Published in Science (American Association for the Advancement of Science) (23.08.2024)
Published in Science (American Association for the Advancement of Science) (23.08.2024)
Get full text
Journal Article
Activity‐dependent dysfunctional gene expression patterns are normalized by in vivo treatment of late‐stage Aβ pathology mice with a TrkB/C small molecule ligand
Latif‐Hernandez, Amira, Moran‐Losada, Patricia, Yang, Tao, Tran, Kevin C, Liu, Harry, Butler, Robert R., Massa, Stephen M., Longo, Frank M.
Published in Alzheimer's & dementia (01.12.2021)
Published in Alzheimer's & dementia (01.12.2021)
Get full text
Journal Article