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The AT04A vaccine against proprotein convertase subtilisin/kexin type 9 reduces total cholesterol, vascular inflammation, and atherosclerosis in APOE3Leiden.CETP mice
Landlinger, Christine, Pouwer, Marianne G., Juno, Claudia, van der Hoorn, José W.A., Pieterman, Elsbet J., Jukema, J. Wouter, Staffler, Guenther, Princen, Hans M.G., Galabova, Gergana
Published in European heart journal (21.08.2017)
Published in European heart journal (21.08.2017)
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Journal Article
A phase I study assessing the safety, tolerability, immunogenicity, and low-density lipoprotein cholesterol-lowering activity of immunotherapeutics targeting PCSK9
Zeitlinger, Markus, Bauer, Martin, Reindl-Schwaighofer, Roman, Stoekenbroek, Robert M., Lambert, Gilles, Berger-Sieczkowski, Evelyn, Lagler, Heimo, Oesterreicher, Zoe, Wulkersdorfer, Beatrix, Lührs, Petra, Galabova, Gergana, Schwenke, Carsten, Mader, Robert M., Medori, Rossella, Landlinger, Christine, Kutzelnigg, Alexandra, Staffler, Günther
Published in European journal of clinical pharmacology (01.10.2021)
Published in European journal of clinical pharmacology (01.10.2021)
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Journal Article
Active immunization against complement factor C5a: a new therapeutic approach for Alzheimer’s disease
Landlinger, Christine, Oberleitner, Lisa, Gruber, Petra, Noiges, Birgit, Yatsyk, Kristyna, Santic, Radmila, Mandler, Markus, Staffler, Guenther
Published in Journal of neuroinflammation (16.08.2015)
Published in Journal of neuroinflammation (16.08.2015)
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Journal Article
Engineered Phage Endolysin Eliminates Gardnerella Biofilm without Damaging Beneficial Bacteria in Bacterial Vaginosis Ex Vivo
Landlinger, Christine, Tisakova, Lenka, Oberbauer, Vera, Schwebs, Timo, Muhammad, Abbas, Latka, Agnieszka, Van Simaey, Leen, Vaneechoutte, Mario, Guschin, Alexander, Resch, Gregory, Swidsinski, Sonja, Swidsinski, Alexander, Corsini, Lorenzo
Published in Pathogens (Basel) (08.01.2021)
Published in Pathogens (Basel) (08.01.2021)
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Journal Article
Optimization of Propidium Monoazide qPCR (Viability-qPCR) to Quantify the Killing by the Gardnerella-Specific Endolysin PM-477, Directly in Vaginal Samples from Women with Bacterial Vaginosis
Latka, Agnieszka, Van Simaey, Leen, Reynders, Marijke, Cools, Piet, Rogier, Tess, Lebbe, Barbara, Corsini, Lorenzo, Landlinger, Christine, Vaneechoutte, Mario
Published in Antibiotics (Basel) (15.01.2022)
Published in Antibiotics (Basel) (15.01.2022)
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Journal Article
ON104, a novel antibody targeting oxidized Macrophage Migration Inhibitory Factor (oxMIF) shows efficacy in preclinical models of chronic inflammation
FERHAT, Maroua, LANDLINGER, Christine, KERSCHBAUMER, Randolf, TAM, Frederick W. K., NICOLETTI, Ferdinando, THIELE, Michael
Published in The Journal of immunology (1950) (01.05.2023)
Published in The Journal of immunology (1950) (01.05.2023)
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Journal Article
The newly engineered monoclonal antibody ON104, targeting the oxidized Macrophage Migration Inhibitory Factor (oxMIF), ameliorates clinical and histopathological signs of collagen-induced arthritis
Ferhat, Maroua, Mangano, Katia, Mirkina, Irina, Mayer, Julia, Rossmueller, Gregor, Schinagl, Alexander, Kerschbaumer, Randolf, Nicoletti, Ferdinando, Thiele, Michael, Landlinger, Christine
Published in European journal of pharmacology (05.10.2023)
Published in European journal of pharmacology (05.10.2023)
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Journal Article
6547 ON104, A NOVEL BIOENGINEERED ANTIBODY TARGETING OXIDIZED MACROPHAGE MIGRATION INHIBITORY FACTOR (OXMIF) AMELIORATES EXPERIMENTAL GLOMERULONEPHRITIS
Ferhat, Maroua, Kerschbaumer, Randolf, Tam, Frederick, Prendecki, Maria, Costa, Lyndon, Thiele, Michael, Landlinger, Christine
Published in Nephrology, dialysis, transplantation (14.06.2023)
Published in Nephrology, dialysis, transplantation (14.06.2023)
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Journal Article
Preclinical Data on the Gardnerella -Specific Endolysin PM-477 Indicate Its Potential to Improve the Treatment of Bacterial Vaginosis through Enhanced Biofilm Removal and Avoidance of Resistance
Landlinger, Christine, Oberbauer, Vera, Podpera Tisakova, Lenka, Schwebs, Timo, Berdaguer, Rocío, Van Simaey, Leen, Vaneechoutte, Mario, Corsini, Lorenzo
Published in Antimicrobial agents and chemotherapy (17.05.2022)
Published in Antimicrobial agents and chemotherapy (17.05.2022)
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Journal Article
Metronidazole Resistance Is a Major Impediment for the Antibiotic Therapy in Bacterial Vaginosis and May Be Overcome with The Gardnerella-Specific Endolysin PM-477
Landlinger, Christine, Tišáková, Lenka, Oberbauer, Vera, Schwebs, Timo, Vaneechoutte, Mario, Swidsinski, Alexander, Corsini, Lorenzo
Published in American journal of obstetrics and gynecology (01.02.2022)
Published in American journal of obstetrics and gynecology (01.02.2022)
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Journal Article
Targeting of oxidized Macrophage Migration Inhibitory Factor
Ferhat, Maroua, Mayer, Julia, Costa, Lyndon H, Prendecki, Maria, Tarazona, Alejandro A. Puchol, Schinagl, Alexander, Kerschbaumer, Randolf J, Tam, Frederick W. K, Landlinger, Christine, Thiele, Michael
Published in PloS one (07.10.2024)
Published in PloS one (07.10.2024)
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Journal Article
Targeting of oxidized Macrophage Migration Inhibitory Factor (oxMIF) with antibody ON104 attenuates the severity of glomerulonephritis
Ferhat, Maroua, Mayer, Julia, Costa, Lyndon H., Prendecki, Maria, Tarazona, Alejandro A. Puchol, Schinagl, Alexander, Kerschbaumer, Randolf J., Tam, Frederick W. K., Landlinger, Christine, Thiele, Michael
Published in PloS one (07.10.2024)
Published in PloS one (07.10.2024)
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Journal Article
1059 ON203: A new antibody targeting the oxidized form of macrophage migration inhibitory factor (oxMIF) exerts antitumorigenic activity and modulates the tumor microenvironment
Maurer, Barbara, Mirkina, Irina, Mayer, Julia, Landlinger, Christine, Schinagl, Alexander, Thiele, Michael, Kerschbaumer, Randolf
Published in Journal for immunotherapy of cancer (01.11.2022)
Published in Journal for immunotherapy of cancer (01.11.2022)
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Journal Article
Myristoylation of human LanC-like Protein 2 (LANCL2) is essential for the interaction with the plasma membrane and the increase in cellular sensitivity to adriamycin
Landlinger, Christine, Salzer, Ulrich, Prohaska, Rainer
Published in Biochimica et biophysica acta (01.11.2006)
Published in Biochimica et biophysica acta (01.11.2006)
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Journal Article
Peptide-based vaccination against OPN integrin binding sites does not improve cardio-metabolic disease in mice
Grün, Nicole G., Strohmeier, Karin, Moreno-Viedma, Veronica, Le Bras, Marie, Landlinger, Christine, Zeyda, Karina, Wanko, Bettina, Leitner, Lukas, Staffler, Günther, Zeyda, Maximilian, Stulnig, Thomas M.
Published in Immunology letters (01.11.2016)
Published in Immunology letters (01.11.2016)
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Journal Article
Diagnosis of Invasive Fungal Infections by a Real-Time Panfungal PCR Assay in Pediatric Patients Undergoing Intensive Chemotherapy or Allogeneic Stem Cell Transplantion
Landlinger, Christine, Baskova, Lenka, Preuner, Sandra, Grotel, Martine Van, Hartwig, Nico G., Heuvel, Marry M. van den, Lion, Thomas
Published in Blood (20.11.2009)
Published in Blood (20.11.2009)
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Journal Article
Rapid Detection of Invasive Fungal Infections in Hemato-Oncological Patients
Landlinger, Christine, Baskova, Lenka, Preuner, Sandra, Van Grotel, Martine, Hartwig, Nico G., van den Heuvel-Eibrink, Marry M., Lion, Thomas
Published in Blood (16.11.2008)
Published in Blood (16.11.2008)
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Journal Article