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The nucleolus as a multiphase liquid condensate
Lafontaine, Denis L. J., Riback, Joshua A., Bascetin, Rümeyza, Brangwynne, Clifford P.
Published in Nature reviews. Molecular cell biology (01.03.2021)
Published in Nature reviews. Molecular cell biology (01.03.2021)
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Journal Article
Specialized box C/D snoRNPs act as antisense guides to target RNA base acetylation
Sharma, Sunny, Yang, Jun, van Nues, Rob, Watzinger, Peter, Kötter, Peter, Lafontaine, Denis L. J., Granneman, Sander, Entian, Karl-Dieter
Published in PLoS genetics (24.05.2017)
Published in PLoS genetics (24.05.2017)
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Journal Article
Controlling the material properties and rRNA processing function of the nucleolus using light
Zhu, Lian, Richardson, Tiffany M., Wacheul, Ludivine, Wei, Ming-Tzo, Feric, Marina, Whitney, Gena, Lafontaine, Denis L. J., Brangwynne, Clifford P.
Published in Proceedings of the National Academy of Sciences - PNAS (27.08.2019)
Published in Proceedings of the National Academy of Sciences - PNAS (27.08.2019)
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Journal Article
Systematic mapping of rRNA 2’-O methylation during frog development and involvement of the methyltransferase Fibrillarin in eye and craniofacial development in Xenopus laevis
Delhermite, Jonathan, Tafforeau, Lionel, Sharma, Sunny, Marchand, Virginie, Wacheul, Ludivine, Lattuca, Ruben, Desiderio, Simon, Motorin, Yuri, Bellefroid, Eric, Lafontaine, Denis L. J.
Published in PLoS genetics (18.01.2022)
Published in PLoS genetics (18.01.2022)
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Journal Article
Ribosome biogenesis factor Tsr3 is the aminocarboxypropyl transferase responsible for 18S rRNA hypermodification in yeast and humans
Meyer, Britta, Wurm, Jan Philip, Sharma, Sunny, Immer, Carina, Pogoryelov, Denys, Kötter, Peter, Lafontaine, Denis L. J., Wöhnert, Jens, Entian, Karl-Dieter
Published in Nucleic acids research (19.05.2016)
Published in Nucleic acids research (19.05.2016)
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Journal Article
Glutamine deficiency in solid tumor cells confers resistance to ribosomal RNA synthesis inhibitors
Pan, Melvin, Zorbas, Christiane, Sugaya, Maki, Ishiguro, Kensuke, Kato, Miki, Nishida, Miyuki, Zhang, Hai-Feng, Candeias, Marco M., Okamoto, Akimitsu, Ishikawa, Takamasa, Soga, Tomoyoshi, Aburatani, Hiroyuki, Sakai, Juro, Matsumura, Yoshihiro, Suzuki, Tsutomu, Proud, Christopher G., Lafontaine, Denis L. J., Osawa, Tsuyoshi
Published in Nature communications (28.06.2022)
Published in Nature communications (28.06.2022)
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Journal Article
The catalytic activity of the translation termination factor methyltransferase Mtq2-Trm112 complex is required for large ribosomal subunit biogenesis
Lacoux, Caroline, Wacheul, Ludivine, Saraf, Kritika, Pythoud, Nicolas, Huvelle, Emmeline, Figaro, Sabine, Graille, Marc, Carapito, Christine, Lafontaine, Denis L J, Heurgué-Hamard, Valérie
Published in Nucleic acids research (02.12.2020)
Published in Nucleic acids research (02.12.2020)
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Journal Article
DHX15-independent roles for TFIP11 in U6 snRNA modification, U4/U6.U5 tri-snRNP assembly and pre-mRNA splicing fidelity
Duchemin, Amandine, O’Grady, Tina, Hanache, Sarah, Mereau, Agnès, Thiry, Marc, Wacheul, Ludivine, Michaux, Catherine, Perpète, Eric, Hervouet, Eric, Peixoto, Paul, Ernst, Felix G. M., Audic, Yann, Dequiedt, Franck, Lafontaine, Denis L. J., Mottet, Denis
Published in Nature communications (17.11.2021)
Published in Nature communications (17.11.2021)
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Journal Article
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Nucleolar stress controls mutant Huntington toxicity and monitors Huntington’s disease progression
Sönmez, Aynur, Mustafa, Rasem, Ryll, Salome T., Tuorto, Francesca, Wacheul, Ludivine, Ponti, Donatella, Litke, Christian, Hering, Tanja, Kojer, Kerstin, Koch, Jenniver, Pitzer, Claudia, Kirsch, Joachim, Neueder, Andreas, Kreiner, Grzegorz, Lafontaine, Denis L. J., Orth, Michael, Liss, Birgit, Parlato, Rosanna
Published in Cell death & disease (08.12.2021)
Published in Cell death & disease (08.12.2021)
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Journal Article
Amaryllidaceae Alkaloids Decrease the Proliferation, Invasion, and Secretion of Clinically Relevant Cytokines by Cultured Human Colon Cancer Cells
Mathieu, Veronique, Laguera, Breana, Masi, Marco, Dulanto, Sara Adriana, Bingham, Tanner W., Hernandez, Lucas W., Sarlah, David, Evidente, Antonio, Lafontaine, Denis L. J., Kornienko, Alexander, Lane, Michelle A.
Published in Biomolecules (Basel, Switzerland) (01.09.2022)
Published in Biomolecules (Basel, Switzerland) (01.09.2022)
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Journal Article
Systematic compositional analysis of exosomal extracellular vesicles produced by cells undergoing apoptosis, necroptosis and ferroptosis
Cappe, Benjamin, Vadi, Mike, Sack, Eliza, Wacheul, Ludivine, Verstraeten, Bruno, Dufour, Sara, Franck, Julien, Xie, Wei, Impens, Francis, Hendrix, An, Lafontaine, Denis L. J., Vandenabeele, Peter, Riquet, Franck B.
Published in Journal of extracellular vesicles (01.10.2023)
Published in Journal of extracellular vesicles (01.10.2023)
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Journal Article
Involvement of human ribosomal proteins in nucleolar structure and p53-dependent nucleolar stress
Nicolas, Emilien, Parisot, Pascaline, Pinto-Monteiro, Celina, de Walque, Roxane, De Vleeschouwer, Christophe, Lafontaine, Denis L. J.
Published in Nature communications (06.06.2016)
Published in Nature communications (06.06.2016)
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Journal Article
HydraPsiSeq: a method for systematic and quantitative mapping of pseudouridines in RNA
Marchand, Virginie, Pichot, Florian, Neybecker, Paul, Ayadi, Lilia, Bourguignon-Igel, Valérie, Wacheul, Ludivine, Lafontaine, Denis L J, Pinzano, Astrid, Helm, Mark, Motorin, Yuri
Published in Nucleic acids research (04.11.2020)
Published in Nucleic acids research (04.11.2020)
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Journal Article
Melanoma addiction to the long non-coding RNA SAMMSON
Leucci, Eleonora, Vendramin, Roberto, Spinazzi, Marco, Laurette, Patrick, Fiers, Mark, Wouters, Jasper, Radaelli, Enrico, Eyckerman, Sven, Leonelli, Carina, Vanderheyden, Katrien, Rogiers, Aljosja, Hermans, Els, Baatsen, Pieter, Aerts, Stein, Amant, Frederic, Van Aelst, Stefan, van den Oord, Joost, de Strooper, Bart, Davidson, Irwin, Lafontaine, Denis L. J., Gevaert, Kris, Vandesompele, Jo, Mestdagh, Pieter, Marine, Jean-Christophe
Published in Nature (London) (24.03.2016)
Published in Nature (London) (24.03.2016)
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Journal Article
The reverse transcription signature of N -1-methyladenosine in RNA-Seq is sequence dependent
Hauenschild, Ralf, Tserovski, Lyudmil, Schmid, Katharina, Thüring, Kathrin, Winz, Marie-Luise, Sharma, Sunny, Entian, Karl-Dieter, Wacheul, Ludivine, Lafontaine, Denis L. J., Anderson, James, Alfonzo, Juan, Hildebrandt, Andreas, Jäschke, Andres, Motorin, Yuri, Helm, Mark
Published in Nucleic acids research (16.11.2015)
Published in Nucleic acids research (16.11.2015)
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Journal Article
Yeast Kre33 and human NAT10 are conserved 18S rRNA cytosine acetyltransferases that modify tRNAs assisted by the adaptor Tan1/THUMPD1
Sharma, Sunny, Langhendries, Jean-Louis, Watzinger, Peter, Kötter, Peter, Entian, Karl-Dieter, Lafontaine, Denis L.J.
Published in Nucleic acids research (27.02.2015)
Published in Nucleic acids research (27.02.2015)
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Journal Article
Screening the Budding Yeast Genome Reveals Unique Factors Affecting K2 Toxin Susceptibility
Servienė, Elena, Lukša, Juliana, Orentaitė, Irma, Lafontaine, Denis L. J., Urbonavičius, Jaunius
Published in PloS one (05.12.2012)
Published in PloS one (05.12.2012)
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Journal Article