Vyzkoušejte nový nástroj s podporou AI
Summon Research Assistant
BETA
Studies on the mechanism of general anesthesia
Pavel, Mahmud Arif, Petersen, E. Nicholas, Wang, Hao, Lerner, Richard A., Hansen, Scott B.
Published in Proceedings of the National Academy of Sciences - PNAS (16.06.2020)
Published in Proceedings of the National Academy of Sciences - PNAS (16.06.2020)
Get full text
Journal Article
gem‐Difluoromethylene Alkyne‐Enabled Diverse C−H Functionalization and Application to the on‐DNA Synthesis of Difluorinated Isocoumarins
Gao, Hui, Lin, Shuang, Zhang, Shuning, Chen, Weijie, Liu, Xiawen, Yang, Guang, Lerner, Richard A., Xu, Hongtao, Zhou, Zhi, Yi, Wei
Published in Angewandte Chemie International Edition (25.01.2021)
Published in Angewandte Chemie International Edition (25.01.2021)
Get full text
Journal Article
Antibody 27F3 Broadly Targets Influenza A Group 1 and 2 Hemagglutinins through a Further Variation in VH1-69 Antibody Orientation on the HA Stem
Lang, Shanshan, Xie, Jia, Zhu, Xueyong, Wu, Nicholas C., Lerner, Richard A., Wilson, Ian A.
Published in Cell reports (Cambridge) (01.09.2017)
Published in Cell reports (Cambridge) (01.09.2017)
Get full text
Journal Article
A DNA-encoded library for the identification of natural product binders that modulate poly (ADP-ribose) polymerase 1, a validated anti-cancer target
Li, Jie, Li, Yu, Lu, Fengping, Liu, Lili, Ji, Qun, Song, Ke, Yin, Qianqian, Lerner, Richard A., Yang, Guang, Xu, Hongtao, Ma, Peixiang
Published in Biochemical and biophysical research communications (03.12.2020)
Published in Biochemical and biophysical research communications (03.12.2020)
Get full text
Journal Article
Antibody Libraries as Tools to Discover Functional Antibodies and Receptor Pleiotropism
Lin, Chih-Wei, Lerner, Richard A.
Published in International journal of molecular sciences (16.04.2021)
Published in International journal of molecular sciences (16.04.2021)
Get full text
Journal Article
A cell–cell interaction format for selection of high-affinity antibodies to membrane proteins
Yang, Zhuo, Wan, Yue, Tao, Pingdong, Qiang, Min, Dong, Xue, Lin, Chih-Wei, Yang, Guang, Zheng, Tianqing, Lerner, Richard A.
Published in Proceedings of the National Academy of Sciences - PNAS (23.07.2019)
Published in Proceedings of the National Academy of Sciences - PNAS (23.07.2019)
Get full text
Journal Article
A complex epistatic network limits the mutational reversibility in the influenza hemagglutinin receptor-binding site
Wu, Nicholas C., Thompson, Andrew J., Xie, Jia, Lin, Chih-Wei, Nycholat, Corwin M., Zhu, Xueyong, Lerner, Richard A., Paulson, James C., Wilson, Ian A.
Published in Nature communications (28.03.2018)
Published in Nature communications (28.03.2018)
Get full text
Journal Article
DNA‐Encoded Libraries: Aryl Fluorosulfonates as Versatile Electrophiles Enabling Facile On‐DNA Suzuki, Sonogashira, and Buchwald Reactions
Xu, Hongtao, Ma, Fei, Wang, Nan, Hou, Wei, Xiong, Huan, Lu, Fengping, Li, Jie, Wang, Shuyue, Ma, Peixiang, Yang, Guang, Lerner, Richard A.
Published in Advanced science (01.12.2019)
Published in Advanced science (01.12.2019)
Get full text
Journal Article
Diversity of Functionally Permissive Sequences in the Receptor-Binding Site of Influenza Hemagglutinin
Wu, Nicholas C., Xie, Jia, Zheng, Tianqing, Nycholat, Corwin M., Grande, Geramie, Paulson, James C., Lerner, Richard A., Wilson, Ian A.
Published in Cell host & microbe (14.06.2017)
Published in Cell host & microbe (14.06.2017)
Get full text
Journal Article
In vitro evolution of an influenza broadly neutralizing antibody is modulated by hemagglutinin receptor specificity
Wu, Nicholas C., Grande, Geramie, Turner, Hannah L., Ward, Andrew B., Xie, Jia, Lerner, Richard A., Wilson, Ian A.
Published in Nature communications (15.05.2017)
Published in Nature communications (15.05.2017)
Get full text
Journal Article
Combinatorial antibody libraries from survivors of the Turkish H5N1 avian influenza outbreak reveal virus neutralization strategies
Kashyap, Arun K, Steel, John, Oner, Ahmet F, Dillon, Michael A, Swale, Ryann E, Wall, Katherine M, Perry, Kimberly J, Faynboym, Aleksandr, Ilhan, Mahmut, Horowitz, Michael, Horowitz, Lawrence, Palese, Peter, Bhatt, Ramesh R, Lerner, Richard A
Published in Proceedings of the National Academy of Sciences - PNAS (22.04.2008)
Published in Proceedings of the National Academy of Sciences - PNAS (22.04.2008)
Get full text
Journal Article
Selection of a picomolar antibody that targets CXCR2-mediated neutrophil activation and alleviates EAE symptoms
Shi, Xiaojie, Wan, Yue, Wang, Nan, Xiang, Jiangchao, Wang, Tao, Yang, Xiaofeng, Wang, Ju, Dong, Xuxue, Dong, Liang, Yan, Lei, Li, Yu, Liu, Lili, Hou, Shinchen, Zhong, Zhenwei, Wilson, Ian A., Yang, Bei, Yang, Guang, Lerner, Richard A.
Published in Nature communications (05.05.2021)
Published in Nature communications (05.05.2021)
Get full text
Journal Article
Chemical generation of bispecific antibodies
Doppalapudi, Venkata R., Huang, Jie, Liu, Dingguo, Jin, Ping, Liu, Bin, Li, Lingna, Desharnais, Joel, Hagen, Crystal, Levin, Nancy J., Shields, Michael J., Parish, Michelle, Murphy, Robert E., Rosario, Joselyn Del, Oates, Bryan D., Lai, Jing-Yu, Matin, Marla J., Ainekulu, Zemeda, Bhat, Abhijit, Bradshaw, Curt W., Woodnutt, Gary, Lerner, Richard A., Lappe, Rodney W.
Published in Proceedings of the National Academy of Sciences - PNAS (28.12.2010)
Published in Proceedings of the National Academy of Sciences - PNAS (28.12.2010)
Get full text
Journal Article
A Structurally Distinct Human Mycoplasma Protein that Generically Blocks Antigen-Antibody Union
Grover, Rajesh K., Zhu, Xueyong, Nieusma, Travis, Jones, Teresa, Boero, Isabel, MacLeod, Amanda S., Mark, Adam, Niessen, Sherry, Kim, Helen J., Kong, Leopold, Assad-Garcia, Nacyra, Kwon, Keehwan, Chesi, Marta, Smider, Vaughn V., Salomon, Daniel R., Jelinek, Diane F., Kyle, Robert A., Pyles, Richard B., Glass, John I., Ward, Andrew B., Wilson, Ian A., Lerner, Richard A.
Published in Science (American Association for the Advancement of Science) (07.02.2014)
Published in Science (American Association for the Advancement of Science) (07.02.2014)
Get full text
Journal Article
A new immunochemical strategy for triple-negative breast cancer therapy
Lin, Chih-Wei, Zheng, Tianqing, Grande, Geramie, Nanna, Alex R., Rader, Christoph, Lerner, Richard A.
Published in Scientific reports (21.07.2021)
Published in Scientific reports (21.07.2021)
Get full text
Journal Article