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PRMT5 Inhibition Modulates E2F1 Methylation and Gene-Regulatory Networks Leading to Therapeutic Efficacy in JAK2V617F-Mutant MPN
Pastore, Friederike, Bhagwat, Neha, Pastore, Alessandro, Radzisheuskaya, Aliaksandra, Karzai, Abdul, Krishnan, Aishwarya, Li, Bing, Bowman, Robert L., Xiao, Wenbin, Viny, Aaron D., Zouak, Anouar, Park, Young C., Cordner, Keith B., Braunstein, Stephanie, Maag, Jesper L., Grego, Alexander, Mehta, Jaanvi, Wang, Min, Lin, Hong, Durham, Benjamin H., Koche, Richard P., Rampal, Raajit K., Helin, Kristian, Scherle, Peggy, Vaddi, Kris, Levine, Ross L.
Published in Cancer discovery (01.11.2020)
Published in Cancer discovery (01.11.2020)
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Journal Article
Engineering a humanized animal model of polycythemia vera with minimal JAK2V617F mutant allelic burden
Parsons, Tyler M., Krishnan, Aishwarya, Dunuwille, Wangisa M.B., Young, Andrew L., Arand, Jason, Han, Wentao, Challen, Grant A.
Published in Haematologica (Roma) (01.03.2024)
Published in Haematologica (Roma) (01.03.2024)
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Journal Article
Therapeutic Efficacy of Combined JAK1/2, Pan-PIM, and CDK4/6 Inhibition in Myeloproliferative Neoplasms
Rampal, Raajit K., Pinzon-Ortiz, Maria, Somasundara, Amritha Varshini Hanasoge, Durham, Benjamin, Koche, Richard, Spitzer, Barbara, Mowla, Shoron, Krishnan, Aishwarya, Li, Bing, An, Wenbin, Derkach, Andriy, Devlin, Sean, Rong, Xianhui, Longmire, Tyler, Eisman, Shira Esther, Cordner, Keith, Whitfield, Justin T., Vanasse, Gary, Cao, Zhu A., Levine, Ross L.
Published in Clinical cancer research (15.06.2021)
Published in Clinical cancer research (15.06.2021)
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Journal Article
Morphological variations of the condylar head among children aged 4-15 years: A panoramic study
Hegde, Rahul, Shigli, Anand, Gawali, Pritesh, Krishnan, Aishwarya, Jadhav, Geetanjali, Raheja, Soniya
Published in Journal of the Indian Society of Pedodontics and Preventive Dentistry (01.10.2021)
Published in Journal of the Indian Society of Pedodontics and Preventive Dentistry (01.10.2021)
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Journal Article
Evaluating the mucolytic effectiveness of Ambroxol and N-Acetylcysteine in patients with Acute exacerbation of chronic obstructive pulmonary disease
Anil, Aswin A., Rajesh, Devendu, Krishnan, Aishwarya Laxmi, Arun, Ciciliya, Thomas, Rosemary, Chandra, Prashant, Haridas, Nithya
Published in Clinical epidemiology and global health (01.11.2024)
Published in Clinical epidemiology and global health (01.11.2024)
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Journal Article
JAK2V617F Mutant MPN Cells Support Parallel Evolution of Independent Leukemic Clones
Parsons, Tyler M, Krishnan, Aishwarya, Young, Andrew L, Cox, Maggie, Oh, Stephen, Challen, Grant A
Published in Blood (05.11.2024)
Published in Blood (05.11.2024)
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Journal Article
675 Goal setting by adolescents with cerebral palsy – a qualitative service review
Krishnan, Aishwarya, Gladstone, Melissa, Mithyantha, Renuka, Sule, Reshma
Published in Archives of disease in childhood (01.08.2022)
Published in Archives of disease in childhood (01.08.2022)
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Journal Article
Cell-extrinsic factors contribute toward myeloid-biased expansion in Tet2-mutant clonal hematopoiesis
Krishnan, Aishwarya, Miles, Linde A., Challen, Grant A.
Published in Experimental hematology (01.08.2025)
Published in Experimental hematology (01.08.2025)
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Journal Article
Mutational Profile of Children with Myeloproliferative Neoplasms
Rutherford, Kayleigh, Farnoud, Noushin, Krishnan, Aishwarya, Rampal, Raajit K, Levine, Ross L., Kucine, Nicole
Published in Blood (15.11.2022)
Published in Blood (15.11.2022)
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Journal Article
Engineering a humanized animal model of polycythemia vera with minimal JAK2 V617F mutant allelic burden
Parsons, Tyler M, Krishnan, Aishwarya, Dunuwille, Wangisa M B, Young, Andrew L, Arand, Jason, Han, Wentao, Challen, Grant A
Published in Haematologica (Roma) (01.03.2024)
Published in Haematologica (Roma) (01.03.2024)
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Journal Article
Abstract P073: Targeting JAK1 signaling for molecular prevention in clonal hematopoiesis
Vela, Pablo Sánchez, Benitez, Anthony Martinez, Krishnan, Aishwarya, Kleppe, Maria, Cai, Sheng F., Levine, Ross L.
Published in Cancer prevention research (Philadelphia, Pa.) (01.01.2023)
Published in Cancer prevention research (Philadelphia, Pa.) (01.01.2023)
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Journal Article
Dnmt3a Controls Hematopoietic Stem Cells Via DNA Methylation-Independent Regulation of Telomeres
Xavier Raj, Infencia, Koh, Won Kyun, Harrison, Jessica, Zhang, Christine RC, Soares, Barbara, Krishnan, Aishwarya, Bjeije, Hassan, Parsons, Tyler M, Han, Wentao, Young, Andrew L, Wang, Ting, Batista, Luis, Challen, Grant A
Published in Blood (05.11.2024)
Published in Blood (05.11.2024)
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Journal Article
CXCL8/CXCR2 signaling mediates bone marrow fibrosis and is a therapeutic target in myelofibrosis
Dunbar, Andrew J., Kim, Dongjoo, Lu, Min, Farina, Mirko, Bowman, Robert L., Yang, Julie L., Park, Young, Karzai, Abdul, Xiao, Wenbin, Zaroogian, Zach, O’Connor, Kavi, Mowla, Shoron, Gobbo, Francesca, Verachi, Paola, Martelli, Fabrizio, Sarli, Giuseppe, Xia, Lijuan, Elmansy, Nada, Kleppe, Maria, Chen, Zhuo, Xiao, Yang, McGovern, Erin, Snyder, Jenna, Krishnan, Aishwarya, Hill, Corrine, Cordner, Keith, Zouak, Anouar, Salama, Mohamed E., Yohai, Jayden, Tucker, Eric, Chen, Jonathan, Zhou, Jing, McConnell, Timothy, Migliaccio, Anna R., Koche, Richard, Rampal, Raajit, Fan, Rong, Levine, Ross L., Hoffman, Ronald
Published in Blood (18.05.2023)
Published in Blood (18.05.2023)
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Journal Article