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Systematic Phenomics Analysis Deconvolutes Genes Mutated in Intellectual Disability into Biologically Coherent Modules
Kochinke, Korinna, Zweier, Christiane, Nijhof, Bonnie, Fenckova, Michaela, Cizek, Pavel, Honti, Frank, Keerthikumar, Shivakumar, Oortveld, Merel A.W., Kleefstra, Tjitske, Kramer, Jamie M., Webber, Caleb, Huynen, Martijn A., Schenck, Annette
Published in American journal of human genetics (07.01.2016)
Published in American journal of human genetics (07.01.2016)
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Journal Article
Functional convergence of histone methyltransferases EHMT1 and KMT2C involved in intellectual disability and autism spectrum disorder
Koemans, Tom S., Kleefstra, Tjitske, Chubak, Melissa C., Stone, Max H., Reijnders, Margot R. F., de Munnik, Sonja, Willemsen, Marjolein H., Fenckova, Michaela, Stumpel, Connie T. R. M., Bok, Levinus A., Sifuentes Saenz, Margarita, Byerly, Kyna A., Baughn, Linda B., Stegmann, Alexander P. A., Pfundt, Rolph, Zhou, Huiqing, van Bokhoven, Hans, Schenck, Annette, Kramer, Jamie M.
Published in PLoS genetics (25.10.2017)
Published in PLoS genetics (25.10.2017)
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Journal Article
Restoring polyamines protects from age-induced memory impairment in an autophagy-dependent manner
Gupta, Varun K, Scheunemann, Lisa, Eisenberg, Tobias, Mertel, Sara, Bhukel, Anuradha, Koemans, Tom S, Kramer, Jamie M, Liu, Karen S Y, Schroeder, Sabrina, Stunnenberg, Hendrik G, Sinner, Frank, Magnes, Christoph, Pieber, Thomas R, Dipt, Shubham, Fiala, André, Schenck, Annette, Schwaerzel, Martin, Madeo, Frank, Sigrist, Stephan J
Published in Nature neuroscience (01.10.2013)
Published in Nature neuroscience (01.10.2013)
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Journal Article
Trithorax regulates long-term memory in Drosophila through epigenetic maintenance of mushroom body metabolic state and translation capacity
Raun, Nicholas, Jones, Spencer G., Kerr, Olivia, Keung, Crystal, Butler, Emily F., Alka, Kumari, Krupski, Jonathan D., Reid-Taylor, Robert A., Ibrahim, Veyan, Williams, MacKayla, Top, Deniz, Kramer, Jamie M.
Published in PLoS biology (27.01.2025)
Published in PLoS biology (27.01.2025)
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Journal Article
Epigenetic Regulation of Learning and Memory by Drosophila EHMT/G9a
Kramer, Jamie M., Kochinke, Korinna, Oortveld, Merel A. W., Marks, Hendrik, Kramer, Daniela, de Jong, Eiko K., Asztalos, Zoltan, Westwood, J. Timothy, Stunnenberg, Hendrik G., Sokolowski, Marla B., Keleman, Krystyna, Zhou, Huiqing, van Bokhoven, Hans, Schenck, Annette
Published in PLoS biology (01.01.2011)
Published in PLoS biology (01.01.2011)
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Journal Article
A Syndromic Neurodevelopmental Disorder Caused by Mutations in SMARCD1, a Core SWI/SNF Subunit Needed for Context-Dependent Neuronal Gene Regulation in Flies
Nixon, Kevin C.J., Rousseau, Justine, Stone, Max H., Sarikahya, Mohammed, Ehresmann, Sophie, Mizuno, Seiji, Matsumoto, Naomichi, Miyake, Noriko, Baralle, Diana, McKee, Shane, Izumi, Kosuke, Ritter, Alyssa L., Heide, Solveig, Héron, Delphine, Depienne, Christel, Titheradge, Hannah, Kramer, Jamie M., Campeau, Philippe M.
Published in American journal of human genetics (04.04.2019)
Published in American journal of human genetics (04.04.2019)
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Journal Article
The histone methyltransferase G9a regulates tolerance to oxidative stress–induced energy consumption
Riahi, Human, Brekelmans, Carlijn, Foriel, Sarah, Merkling, Sarah H., Lyons, Taylor A., Itskov, Pavel M., Kleefstra, Tjitske, Ribeiro, Carlos, van Rij, Ronald P., Kramer, Jamie M., Schenck, Annette
Published in PLoS biology (12.03.2019)
Published in PLoS biology (12.03.2019)
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Journal Article
Mutations in the chromatin modifier gene KANSL1 cause the 17q21.31 microdeletion syndrome
Koolen, David A, Kramer, Jamie M, Neveling, Kornelia, Nillesen, Willy M, Moore-Barton, Heather L, Elmslie, Frances V, Toutain, Annick, Amiel, Jeanne, Malan, Valérie, Tsai, Anne Chun-Hui, Cheung, Sau Wai, Gilissen, Christian, Verwiel, Eugene T P, Martens, Sarah, Feuth, Ton, Bongers, Ernie M H F, de Vries, Petra, Scheffer, Hans, Vissers, Lisenka E L M, de Brouwer, Arjan P M, Brunner, Han G, Veltman, Joris A, Schenck, Annette, Yntema, Helger G, de Vries, Bert B A
Published in Nature genetics (01.06.2012)
Published in Nature genetics (01.06.2012)
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Journal Article
Conditional depletion of intellectual disability and Parkinsonism candidate gene ATP6AP2 in fly and mouse induces cognitive impairment and neurodegeneration
Dubos, Aline, Castells-Nobau, Anna, Meziane, Hamid, Oortveld, Merel A.W., Houbaert, Xander, Iacono, Giovanni, Martin, Christelle, Mittelhaeuser, Christophe, Lalanne, Valérie, Kramer, Jamie M., Bhukel, Anuradha, Quentin, Christine, Slabbert, Jan, Verstreken, Patrik, Sigrist, Stefan J., Messaddeq, Nadia, Birling, Marie-Christine, Selloum, Mohammed, Stunnenberg, Henk G., Humeau, Yann, Schenck, Annette, Herault, Yann
Published in Human molecular genetics (01.12.2015)
Published in Human molecular genetics (01.12.2015)
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Journal Article
Conserved regulation of neurodevelopmental processes and behavior by FoxP in Drosophila
Castells-Nobau, Anna, Eidhof, Ilse, Fenckova, Michaela, Brenman-Suttner, Dova B., Scheffer-de Gooyert, Jolanda M., Christine, Sheren, Schellevis, Rosa L., van der Laan, Kiran, Quentin, Christine, van Ninhuijs, Lisa, Hofmann, Falko, Ejsmont, Radoslaw, Fisher, Simon E., Kramer, Jamie M., Sigrist, Stephan J., Simon, Anne F., Schenck, Annette
Published in PloS one (12.02.2019)
Published in PloS one (12.02.2019)
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Journal Article
Mushroom Body Specific Transcriptome Analysis Reveals Dynamic Regulation of Learning and Memory Genes After Acquisition of Long-Term Courtship Memory in Drosophila
Jones, Spencer G, Nixon, Kevin C J, Chubak, Melissa C, Kramer, Jamie M
Published in G3 : genes - genomes - genetics (01.11.2018)
Published in G3 : genes - genomes - genetics (01.11.2018)
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Journal Article
Individual components of the SWI/SNF chromatin remodelling complex have distinct roles in memory neurons of the Drosophila mushroom body
Chubak, Melissa C., Nixon, Kevin C. J., Stone, Max H., Raun, Nicholas, Rice, Shelby L., Sarikahya, Mohammed, Jones, Spencer G., Lyons, Taylor A., Jakub, Taryn E., Mainland, Roslyn L. M., Knip, Maria J., Edwards, Tara N., Kramer, Jamie M.
Published in Disease models & mechanisms (01.03.2019)
Published in Disease models & mechanisms (01.03.2019)
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Journal Article
Ubiquitin Ligase HUWE1 Regulates Axon Branching through the Wnt/β-Catenin Pathway in a Drosophila Model for Intellectual Disability
Vandewalle, Joke, Langen, Marion, Zschaetzsch, Marlen, Nijhof, Bonnie, Kramer, Jamie M., Brems, Hilde, Bauters, Marijke, Lauwers, Elsa, Srahna, Mohammed, Marynen, Peter, Verstreken, Patrik, Schenck, Annette, Hassan, Bassem A., Froyen, Guy
Published in PloS one (26.11.2013)
Published in PloS one (26.11.2013)
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Journal Article
Epigenetic mechanisms modulate differences in Drosophila foraging behavior
Anreiter, Ina, Kramer, Jamie M., Sokolowski, Marla B.
Published in Proceedings of the National Academy of Sciences - PNAS (21.11.2017)
Published in Proceedings of the National Academy of Sciences - PNAS (21.11.2017)
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Journal Article