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Genome-wide association study of alcohol consumption and use disorder in 274,424 individuals from multiple populations
Kranzler, Henry R., Zhou, Hang, Kember, Rachel L., Vickers Smith, Rachel, Justice, Amy C., Damrauer, Scott, Tsao, Philip S., Klarin, Derek, Baras, Aris, Reid, Jeffrey, Overton, John, Rader, Daniel J., Cheng, Zhongshan, Tate, Janet P., Becker, William C., Concato, John, Xu, Ke, Polimanti, Renato, Zhao, Hongyu, Gelernter, Joel
Published in Nature communications (02.04.2019)
Published in Nature communications (02.04.2019)
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Journal Article
Long-Term Cardiovascular Risk in Women With Hypertension During Pregnancy
Honigberg, Michael C., Zekavat, Seyedeh Maryam, Aragam, Krishna, Klarin, Derek, Bhatt, Deepak L., Scott, Nandita S., Peloso, Gina M., Natarajan, Pradeep
Published in Journal of the American College of Cardiology (03.12.2019)
Published in Journal of the American College of Cardiology (03.12.2019)
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Journal Article
A multiancestry genome-wide association study of unexplained chronic ALT elevation as a proxy for nonalcoholic fatty liver disease with histological and radiological validation
Vujkovic, Marijana, Ramdas, Shweta, Lorenz, Kim M., Guo, Xiuqing, Darlay, Rebecca, Cordell, Heather J., He, Jing, Gindin, Yevgeniy, Chung, Chuhan, Myers, Robert P., Schneider, Carolin V., Park, Joseph, Lee, Kyung Min, Serper, Marina, Carr, Rotonya M., Kaplan, David E., Haas, Mary E., MacLean, Matthew T., Witschey, Walter R., Zhu, Xiang, Tcheandjieu, Catherine, Kember, Rachel L., Kranzler, Henry R., Verma, Anurag, Giri, Ayush, Klarin, Derek M., Sun, Yan V., Huang, Jie, Huffman, Jennifer E., Creasy, Kate Townsend, Hand, Nicholas J., Liu, Ching-Ti, Long, Michelle T., Yao, Jie, Budoff, Matthew, Tan, Jingyi, Li, Xiaohui, Lin, Henry J., Chen, Yii-Der Ida, Taylor, Kent D., Chang, Ruey-Kang, Krauss, Ronald M., Vilarinho, Silvia, Brancale, Joseph, Nielsen, Jonas B., Locke, Adam E., Jones, Marcus B., Verweij, Niek, Baras, Aris, Reddy, K. Rajender, Neuschwander-Tetri, Brent A., Schwimmer, Jeffrey B., Sanyal, Arun J., Chalasani, Naga, Ryan, Kathleen A., Mitchell, Braxton D., Gill, Dipender, Wells, Andrew D., Manduchi, Elisabetta, Saiman, Yedidya, Mahmud, Nadim, Miller, Donald R., Reaven, Peter D., Phillips, Lawrence S., Muralidhar, Sumitra, DuVall, Scott L., Lee, Jennifer S., Assimes, Themistocles L., Pyarajan, Saiju, Cho, Kelly, Edwards, Todd L., Damrauer, Scott M., Wilson, Peter W., Gaziano, J. Michael, O’Donnell, Christopher J., Khera, Amit V., Grant, Struan F. A., Brown, Christopher D., Tsao, Philip S., Saleheen, Danish, Lotta, Luca A., Bastarache, Lisa, Anstee, Quentin M., Daly, Ann K., Meigs, James B., Rotter, Jerome I., Lynch, Julie A., Rader, Daniel J., Voight, Benjamin F., Chang, Kyong-Mi
Published in Nature genetics (01.06.2022)
Published in Nature genetics (01.06.2022)
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Journal Article
Risk factors mediating the effect of body mass index and waist-to-hip ratio on cardiovascular outcomes: Mendelian randomization analysis
Gill, Dipender, Zuber, Verena, Dawson, Jesse, Pearson-Stuttard, Jonathan, Carter, Alice R., Sanderson, Eleanor, Karhunen, Ville, Levin, Michael G., Wootton, Robyn E., Klarin, Derek, Tsao, Philip S., Tsilidis, Konstantinos K., Damrauer, Scott M., Burgess, Stephen, Elliott, Paul
Published in International Journal of Obesity (01.07.2021)
Published in International Journal of Obesity (01.07.2021)
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Journal Article
The relationship between circulating lipids and breast cancer risk: A Mendelian randomization study
Johnson, Kelsey E., Siewert, Katherine M., Klarin, Derek, Damrauer, Scott M., Chang, Kyong-Mi, Tsao, Philip S., Assimes, Themistocles L., Maxwell, Kara N., Voight, Benjamin F.
Published in PLoS medicine (01.09.2020)
Published in PLoS medicine (01.09.2020)
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Journal Article
Genetic Analysis of Venous Thromboembolism in UK Biobank Identifies the ZFPM2 Locus and Implicates Obesity as a Causal Risk Factor
Klarin, Derek, Emdin, Connor A., Natarajan, Pradeep, Conrad, Mark F., Kathiresan, Sekar
Published in Circulation. Cardiovascular genetics (01.04.2017)
Published in Circulation. Cardiovascular genetics (01.04.2017)
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Journal Article
Genetic analysis in UK Biobank links insulin resistance and transendothelial migration pathways to coronary artery disease
Klarin, Derek, Zhu, Qiuyu Martin, Emdin, Connor A, Chaffin, Mark, Horner, Steven, McMillan, Brian J, Leed, Alison, Weale, Michael E, Spencer, Chris C A, Aguet, François, Segrè, Ayellet V, Ardlie, Kristin G, Khera, Amit V, Kaushik, Virendar K, Natarajan, Pradeep, Kathiresan, Sekar
Published in Nature genetics (01.09.2017)
Published in Nature genetics (01.09.2017)
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Journal Article
Prioritizing the Role of Major Lipoproteins and Subfractions as Risk Factors for Peripheral Artery Disease
Levin, Michael G., Zuber, Verena, Walker, Venexia M., Klarin, Derek, Lynch, Julie, Malik, Rainer, Aday, Aaron W., Bottolo, Leonardo, Pradhan, Aruna D., Dichgans, Martin, Chang, Kyong-Mi, Rader, Daniel J., Tsao, Philip S., Voight, Benjamin F., Gill, Dipender, Burgess, Stephen, Damrauer, Scott M.
Published in Circulation (New York, N.Y.) (03.08.2021)
Published in Circulation (New York, N.Y.) (03.08.2021)
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Journal Article
Heritability of Atrial Fibrillation
Weng, Lu-Chen, Choi, Seung Hoan, Klarin, Derek, Smith, J. Gustav, Loh, Po-Ru, Chaffin, Mark, Roselli, Carolina, Hulme, Olivia L., Lunetta, Kathryn L., Dupuis, Josée, Benjamin, Emelia J., Newton-Cheh, Christopher, Kathiresan, Sekar, Ellinor, Patrick T., Lubitz, Steven A.
Published in Circulation. Cardiovascular genetics (01.12.2017)
Published in Circulation. Cardiovascular genetics (01.12.2017)
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Journal Article
Endothelial lipase mediates efficient lipolysis of triglyceride-rich lipoproteins
Khetarpal, Sumeet A., Vitali, Cecilia, Levin, Michael G., Klarin, Derek, Park, Joseph, Pampana, Akhil, Millar, John S., Kuwano, Takashi, Sugasini, Dhavamani, Subbaiah, Papasani V., Billheimer, Jeffrey T., Natarajan, Pradeep, Rader, Daniel J.
Published in PLoS genetics (20.09.2021)
Published in PLoS genetics (20.09.2021)
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Journal Article
Elevated plasma complement factor H related 5 protein is associated with venous thromboembolism
Iglesias, Maria Jesus, Sanchez-Rivera, Laura, Ibrahim-Kosta, Manal, Naudin, Clément, Munsch, Gaëlle, Goumidi, Louisa, Farm, Maria, Smith, Philip M., Thibord, Florian, Kral-Pointner, Julia Barbara, Hong, Mun-Gwan, Suchon, Pierre, Germain, Marine, Schrottmaier, Waltraud, Dusart, Philip, Boland, Anne, Kotol, David, Edfors, Fredrik, Koprulu, Mine, Pietzner, Maik, Langenberg, Claudia, Damrauer, Scott M., Johnson, Andrew D., Klarin, Derek M., Smith, Nicholas L., Smadja, David M., Holmström, Margareta, Magnusson, Maria, Silveira, Angela, Uhlén, Mathias, Renné, Thomas, Martinez-Perez, Angel, Emmerich, Joseph, Deleuze, Jean-Francois, Antovic, Jovan, Soria Fernandez, Jose Manuel, Assinger, Alice, Schwenk, Jochen M., Souto Andres, Joan Carles, Morange, Pierre-Emmanuel, Butler, Lynn Marie, Trégouët, David-Alexandre, Odeberg, Jacob
Published in Nature communications (07.06.2023)
Published in Nature communications (07.06.2023)
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Journal Article
A Missense Variant in the IL-6 Receptor and Protection From Peripheral Artery Disease
Levin, Michael G., Klarin, Derek, Georgakis, Marios K., Lynch, Julie, Liao, Katherine P., Voight, Benjamin F., O’Donnell, Christopher J., Chang, Kyong-Mi, Assimes, Themistocles L., Tsao, Philip S., Damrauer, Scott M.
Published in Circulation Research (29.10.2021)
Published in Circulation Research (29.10.2021)
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Journal Article
Mendelian Randomization Study of ACLY and Cardiovascular Disease
Klarin, Derek, O’Donnell, Christopher J, Kathiresan, Sekar, Damask, Amy, Paulding, Charles, Baras, Aris, Carey, David, Abecasis, Goncalo R, Hólm, Hilma, Sulem, Patrick, Helgadóttir, Anna, Tragante, Vinicius, Þorleifsson, Guðmar, Guðbjartsson, Daníel, Stefánsson, Kári, Ference, Brian A, Ray, Kausik K, Nicholls, Stephen J
Published in The New England journal of medicine (13.08.2020)
Published in The New England journal of medicine (13.08.2020)
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Journal Article
Concomitant carotid endarterectomy and cardiac surgery does not decrease postoperative stroke rates
Klarin, Derek, Patel, Virendra I., Zhang, Shuaiqi, Xian, Ying, Kosinski, Andrzej, Yerokun, Babatunde, Badhwar, Vinay, Thourani, Vinod H., Sundt, Thoralf M., Shahian, David, Melnitchouk, Serguei
Published in Journal of vascular surgery (01.08.2020)
Published in Journal of vascular surgery (01.08.2020)
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Journal Article
DNA Sequence Variation in ACVR1C Encoding the Activin Receptor-Like Kinase 7 Influences Body Fat Distribution and Protects Against Type 2 Diabetes
Emdin, Connor A., Khera, Amit V., Aragam, Krishna, Haas, Mary, Chaffin, Mark, Klarin, Derek, Natarajan, Pradeep, Bick, Alexander, Zekavat, Seyedeh M., Nomura, Akihiro, Ardissino, Diego, Wilson, James G., Schunkert, Heribert, McPherson, Ruth, Watkins, Hugh, Elosua, Roberto, Bown, Matthew J., Samani, Nilesh J., Baber, Usman, Erdmann, Jeanette, Gupta, Namrata, Danesh, John, Saleheen, Danish, Gabriel, Stacey, Kathiresan, Sekar
Published in Diabetes (New York, N.Y.) (01.01.2019)
Published in Diabetes (New York, N.Y.) (01.01.2019)
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Journal Article
Author Correction: Elevated plasma complement factor H related 5 protein is associated with venous thromboembolism
Iglesias, Maria Jesus, Sanchez-Rivera, Laura, Ibrahim-Kosta, Manal, Naudin, Clément, Munsch, Gaëlle, Goumidi, Louisa, Farm, Maria, Smith, Philip M., Thibord, Florian, Kral-Pointner, Julia Barbara, Hong, Mun-Gwan, Suchon, Pierre, Germain, Marine, Schrottmaier, Waltraud, Dusart, Philip, Boland, Anne, Kotol, David, Edfors, Fredrik, Koprulu, Mine, Pietzner, Maik, Langenberg, Claudia, Damrauer, Scott M., Johnson, Andrew D., Klarin, Derek M., Smith, Nicholas L., Smadja, David M., Holmström, Margareta, Magnusson, Maria, Silveira, Angela, Uhlén, Mathias, Renné, Thomas, Martinez-Perez, Angel, Emmerich, Joseph, Deleuze, Jean-Francois, Antovic, Jovan, Soria Fernandez, Jose Manuel, Assinger, Alice, Schwenk, Jochen M., Souto Andres, Joan Carles, Morange, Pierre-Emmanuel, Butler, Lynn Marie, Trégouët, David-Alexandre, Odeberg, Jacob
Published in Nature communications (27.11.2023)
Published in Nature communications (27.11.2023)
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Journal Article
Evaluation of the Pooled Cohort Equations for Prediction of Cardiovascular Risk in a Contemporary Prospective Cohort
Emdin, Connor A., Khera, Amit V., Natarajan, Pradeep, Klarin, Derek, Baber, Usman, Mehran, Roxana, Rader, Daniel J., Fuster, Valentin, Kathiresan, Sekar
Published in The American journal of cardiology (15.03.2017)
Published in The American journal of cardiology (15.03.2017)
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Journal Article
Risk factor profile and anatomic features of previously asymptomatic patients presenting with carotid-related stroke
Klarin, Derek, Cambria, Richard P., Ergul, Emel A., Silverman, Scott B., Patel, Virendra I., LaMuraglia, Glenn M., Conrad, Mark F., Clouse, W. Darrin
Published in Journal of vascular surgery (01.11.2018)
Published in Journal of vascular surgery (01.11.2018)
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Journal Article
PCSK9 loss of function is protective against extra-coronary atherosclerotic cardiovascular disease in a large multi-ethnic cohort
Small, Aeron M., Huffman, Jennifer E., Klarin, Derek, Lynch, Julie A., Assimes, Themistocles, DuVall, Scott, Sun, Yan V., Shere, Labiba, Natarajan, Pradeep, Gaziano, Michael, Rader, Daniel J., Wilson, Peter W. F., Tsao, Philip S., Chang, Kyong-Mi, Cho, Kelly, O’Donnell, Christopher J., Casas, Juan P., Damrauer, Scott M.
Published in PloS one (09.11.2020)
Published in PloS one (09.11.2020)
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Journal Article