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Candidalysin activates innate epithelial immune responses via epidermal growth factor receptor
Ho, Jemima, Yang, Xuexin, Nikou, Spyridoula-Angeliki, Kichik, Nessim, Donkin, Andrew, Ponde, Nicole O., Richardson, Jonathan P., Gratacap, Remi L., Archambault, Linda S., Zwirner, Christian P., Murciano, Celia, Henley-Smith, Rhonda, Thavaraj, Selvam, Tynan, Christopher J., Gaffen, Sarah L., Hube, Bernhard, Wheeler, Robert T., Moyes, David L., Naglik, Julian R.
Published in Nature communications (24.05.2019)
Published in Nature communications (24.05.2019)
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Journal Article
Candida albicans and candidalysin in inflammatory disorders and cancer
Ho, Jemima, Camilli, Giorgio, Griffiths, James S., Richardson, Jonathan P., Kichik, Nessim, Naglik, Julian R.
Published in Immunology (01.01.2021)
Published in Immunology (01.01.2021)
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Journal Article
Toll-like receptor 4 and CD11b expressed on microglia coordinate eradication of Candida albicans cerebral mycosis
Wu, Yifan, Du, Shuqi, Bimler, Lynn H., Mauk, Kelsey E., Lortal, Léa, Kichik, Nessim, Griffiths, James S., Osicka, Radim, Song, Lizhen, Polsky, Katherine, Kasper, Lydia, Sebo, Peter, Weatherhead, Jill, Knight, J. Morgan, Kheradmand, Farrah, Zheng, Hui, Richardson, Jonathan P., Hube, Bernhard, Naglik, Julian R., Corry, David B.
Published in Cell reports (Cambridge) (31.10.2023)
Published in Cell reports (Cambridge) (31.10.2023)
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Journal Article
Albumin Neutralizes Hydrophobic Toxins and Modulates Candida albicans Pathogenicity
Austermeier, Sophie, Pekmezović, Marina, Porschitz, Pauline, Lee, Sejeong, Kichik, Nessim, Moyes, David L., Ho, Jemima, Kotowicz, Natalia K., Naglik, Julian R., Hube, Bernhard, Gresnigt, Mark S.
Published in mBio (29.06.2021)
Published in mBio (29.06.2021)
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Journal Article
Candidalysins Are a New Family of Cytolytic Fungal Peptide Toxins
Richardson, Jonathan P., Brown, Rhys, Kichik, Nessim, Lee, Sejeong, Priest, Emily, Mogavero, Selene, Maufrais, Corinne, Wickramasinghe, Don N., Tsavou, Antzela, Kotowicz, Natalia K., Hepworth, Olivia W., Gallego-Cortés, Ana, Ponde, Nicole O., Ho, Jemima, Moyes, David L., Wilson, Duncan, D’Enfert, Christophe, Hube, Bernhard, Naglik, Julian R.
Published in mBio (22.02.2022)
Published in mBio (22.02.2022)
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Journal Article
Candida albicans Interactions with Mucosal Surfaces during Health and Disease
Nikou, Spyridoula-Angeliki, Kichik, Nessim, Brown, Rhys, Ponde, Nicole, Ho, Jemima, Naglik, Julian, Richardson, Jonathan
Published in Pathogens (Basel) (22.04.2019)
Published in Pathogens (Basel) (22.04.2019)
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Journal Article
NMR analysis of G-protein βγ subunit complexes reveals a dynamic Gα-Gβγ subunit interface and multiple protein recognition modes
Smrcka, Alan V, Kichik, Nessim, Tarragó, Teresa, Burroughs, Michael, Park, Min-Sun, Itoga, Nathan K, Stern, Harry A, Willardson, Barry M, Giralt, Ernest
Published in Proceedings of the National Academy of Sciences - PNAS (12.01.2010)
Published in Proceedings of the National Academy of Sciences - PNAS (12.01.2010)
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Journal Article
Candidalysin is a fungal peptide toxin critical for mucosal infection
Moyes, David L., Wilson, Duncan, Richardson, Jonathan P., Mogavero, Selene, Tang, Shirley X., Wernecke, Julia, Höfs, Sarah, Gratacap, Remi L., Robbins, Jon, Runglall, Manohursingh, Murciano, Celia, Blagojevic, Mariana, Thavaraj, Selvam, Förster, Toni M., Hebecker, Betty, Kasper, Lydia, Vizcay, Gema, Iancu, Simona I., Kichik, Nessim, Häder, Antje, Kurzai, Oliver, Luo, Ting, Krüger, Thomas, Kniemeyer, Olaf, Cota, Ernesto, Bader, Oliver, Wheeler, Robert T., Gutsmann, Thomas, Hube, Bernhard, Naglik, Julian R.
Published in Nature (London) (07.04.2016)
Published in Nature (London) (07.04.2016)
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Journal Article
Processing of Candida albicans Ece1p Is Critical for Candidalysin Maturation and Fungal Virulence
Richardson, Jonathan P., Mogavero, Selene, Moyes, David L., Blagojevic, Mariana, Krüger, Thomas, Verma, Akash H., Coleman, Bianca M., De La Cruz Diaz, Jacinto, Schulz, Daniela, Ponde, Nicole O., Carrano, Giulia, Kniemeyer, Olaf, Wilson, Duncan, Bader, Oliver, Enoiu, Simona I., Ho, Jemima, Kichik, Nessim, Gaffen, Sarah L., Hube, Bernhard, Naglik, Julian R.
Published in mBio (23.01.2018)
Published in mBio (23.01.2018)
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Journal Article
Baicalin, a prodrug able to reach the CNS, is a prolyl oligopeptidase inhibitor
Tarragó, Teresa, Kichik, Nessim, Claasen, Birgit, Prades, Roger, Teixidó, Meritxell, Giralt, Ernest
Published in Bioorganic & medicinal chemistry (01.08.2008)
Published in Bioorganic & medicinal chemistry (01.08.2008)
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Journal Article
15N Relaxation NMR Studies of Prolyl Oligopeptidase, an 80 kDa Enzyme, Reveal a Pre-existing Equilibrium between Different Conformational States
Kichik, Nessim, Tarragó, Teresa, Claasen, Birgit, Gairí, Margarida, Millet, Oscar, Giralt, Ernest
Published in Chembiochem : a European journal of chemical biology (16.12.2011)
Published in Chembiochem : a European journal of chemical biology (16.12.2011)
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Journal Article
15 N Relaxation NMR Studies of Prolyl Oligopeptidase, an 80 kDa Enzyme, Reveal a Pre‐existing Equilibrium between Different Conformational States
Kichik, Nessim, Tarragó, Teresa, Claasen, Birgit, Gairí, Margarida, Millet, Oscar, Giralt, Ernest
Published in Chembiochem : a European journal of chemical biology (16.12.2011)
Published in Chembiochem : a European journal of chemical biology (16.12.2011)
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Journal Article
A Cost‐Effective Labeling Strategy for the NMR Study of Large Proteins: Selective 15 N‐Labeling of the Tryptophan Side Chains of Prolyl Oligopeptidase
Tarragó, Teresa, Claasen, Birgit, Kichik, Nessim, Rodriguez‐Mias, Ricard A., Gairí, Margarida, Giralt, Ernest
Published in Chembiochem : a European journal of chemical biology (23.11.2009)
Published in Chembiochem : a European journal of chemical biology (23.11.2009)
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Journal Article
Processing of italic toggle="yes">Candida albicans /italic> Ece1p Is Critical for Candidalysin Maturation and Fungal Virulence
Jonathan P. Richardson, Selene Mogavero, David L. Moyes, Mariana Blagojevic, Thomas Krüger, Akash H. Verma, Bianca M. Coleman, Jacinto De La Cruz Diaz, Daniela Schulz, Nicole O. Ponde, Giulia Carrano, Olaf Kniemeyer, Duncan Wilson, Oliver Bader, Simona I. Enoiu, Jemima Ho, Nessim Kichik, Sarah L. Gaffen, Bernhard Hube, Julian R. Naglik
Published in mBio (01.03.2018)
Published in mBio (01.03.2018)
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Journal Article
NMR analysis of G-protein [beta][gamma] subunit complexes reveals a dynamic G[alpha]-G[beta][gamma] subunit interface and multiple protein recognition modes
Smrcka, Alan V, Kichik, Nessim, Tarragó, Teresa, Burroughs, Michael, Park, Min-Sun, Itoga, Nathan K, Stern, Harry A, Willardson, Barry M, Giralt, Ernest
Published in Proceedings of the National Academy of Sciences - PNAS (12.01.2010)
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Published in Proceedings of the National Academy of Sciences - PNAS (12.01.2010)
Journal Article