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The promise of mRNA vaccines: a biotech and industrial perspective
Jackson, Nicholas A. C., Kester, Kent E., Casimiro, Danilo, Gurunathan, Sanjay, DeRosa, Frank
Published in npj vaccines (04.02.2020)
Published in npj vaccines (04.02.2020)
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Journal Article
The Relationship between RTS,S Vaccine-Induced Antibodies, CD4+ T Cell Responses and Protection against Plasmodium falciparum Infection
White, Michael T., Bejon, Philip, Olotu, Ally, Griffin, Jamie T., Riley, Eleanor M., Kester, Kent E., Ockenhouse, Christian F., Ghani, Azra C.
Published in PloS one (16.04.2013)
Published in PloS one (16.04.2013)
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Journal Article
Randomized, Double-Blind, Phase 2a Trial of Falciparum Malaria Vaccines RTS,S/AS01B and RTS,S/AS02A in Malaria-Naive Adults: Safety, Efficacy, and Immunologic Associates of Protection
Kester, Kent E., Cummings, James F., Ofori-Anyinam, Opokua, Ockenhouse, Christian F., Krzych, Urszula, Moris, Philippe, Schwenk, Robert, Nielsen, Robin A., Debebe, Zufan, Pinelis, Evgeny, Juompan, Laure, Williams, Jack, Dowler, Megan, Stewart, V. Ann, Wirtz, Robert A., Dubois, Marie-Claude, Lievens, Marc, Cohen, Joe, Ballou, W. Ripley, Heppner, D. Gray
Published in The Journal of infectious diseases (01.08.2009)
Published in The Journal of infectious diseases (01.08.2009)
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Journal Article
Predicting RTS,S Vaccine-Mediated Protection from Transcriptomes in a Malaria-Challenge Clinical Trial
van den Berg, Robert A., Coccia, Margherita, Ballou, W. Ripley, Kester, Kent E., Ockenhouse, Christian F., Vekemans, Johan, Jongert, Erik, Didierlaurent, Arnaud M., van der Most, Robbert G.
Published in Frontiers in immunology (23.05.2017)
Published in Frontiers in immunology (23.05.2017)
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Journal Article
Phase 1/2a Study of the Malaria Vaccine Candidate Apical Membrane Antigen-1 (AMA-1) Administered in Adjuvant System AS01B or AS02A
Spring, Michele D., Cummings, James F., Ockenhouse, Christian F., Dutta, Sheetij, Reidler, Randall, Angov, Evelina, Bergmann-Leitner, Elke, Stewart, V. Ann, Bittner, Stacey, Juompan, Laure, Kortepeter, Mark G., Nielsen, Robin, Krzych, Urszula, Tierney, Ev, Ware, Lisa A., Dowler, Megan, Hermsen, Cornelus C., Sauerwein, Robert W., de Vlas, Sake J., Ofori-Anyinam, Opokua, Lanar, David E., Williams, Jack L., Kester, Kent E., Tucker, Kathryn, Shi, Meng, Malkin, Elissa, Long, Carole, Diggs, Carter L., Soisson, Lorraine, Dubois, Marie-Claude, Ballou, W. Ripley, Cohen, Joe, Heppner, D. Gray
Published in PloS one (23.04.2009)
Published in PloS one (23.04.2009)
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Journal Article
Protective Immunity Induced with the RTS,S/AS Vaccine Is Associated with IL-2 and TNF-α Producing Effector and Central Memory CD4+ T Cells
Lumsden, Joanne M., Schwenk, Robert J., Rein, Lisa E., Moris, Philippe, Janssens, Michel, Ofori-Anyinam, Opokua, Cohen, Joe, Kester, Kent E., Heppner, D. Gray, Krzych, Urszula
Published in PloS one (2011)
Published in PloS one (2011)
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Journal Article
Expression of genes associated with immunoproteasome processing of major histocompatibility complex peptides is indicative of protection with adjuvanted RTS,S malaria vaccine
Vahey, Maryanne T., Wang, Zhining, Kester, Kent E., Cummings, James, Heppner, D. Gray, Nau, Martin E., Ofori-Anyinam, Opokua, Cohen, Joe, Coche, Thierry, Ballou, W. Ripley, Ockenhouse, Christian F.
Published in The Journal of infectious diseases (15.02.2010)
Published in The Journal of infectious diseases (15.02.2010)
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Journal Article
Evaluation of RTS,S/AS02A and RTS,S/AS01B in Adults in a High Malaria Transmission Area
Polhemus, Mark E., Remich, Shon A., Ogutu, Bernhards R., Waitumbi, John N., Otieno, Lucas, Apollo, Stella, Cummings, James F., Kester, Kent E., Ockenhouse, Christian F., Stewart, Ann, Ofori-Anyinam, Opokua, Ramboer, Isabelle, Cahill, Conor P., Lievens, Marc, Dubois, Marie-Claude, Demoitie, Marie-Ange, Leach, Amanda, Cohen, Joe, Ballou, W. Ripley, Heppner, D. Gray
Published in PloS one (31.07.2009)
Published in PloS one (31.07.2009)
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Journal Article
Common and Divergent Immune Response Signaling Pathways Discovered in Peripheral Blood Mononuclear Cell Gene Expression Patterns in Presymptomatic and Clinically Apparent Malaria
Ockenhouse, Christian F, Hu, Wan-chung, Kester, Kent E, Cummings, James F, Stewart, Ann, Heppner, D. Gray, Jedlicka, Anne E, Scott, Alan L, Wolfe, Nathan D, Vahey, Maryanne, Burke, Donald S
Published in Infection and Immunity (01.10.2006)
Published in Infection and Immunity (01.10.2006)
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Journal Article
Efficacy of Recombinant Circumsporozoite Protein Vaccine Regimens against Experimental Plasmodium falciparum Malaria
Kester, Kent E., McKinney, Denise A., Tornieporth, Nadia, Ockenhouse, Christian F., Heppner, D. Gray, Hall, Ted, Krzych, Urszula, Delchambre, Martine, Voss, Gerald, Dowler, Megan G., Palensky, Jolie, Wittes, Janet, Cohen, Joe, Ballou, W. Ripley
Published in The Journal of infectious diseases (15.02.2001)
Published in The Journal of infectious diseases (15.02.2001)
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Journal Article
UPDATE ON THE CLINICAL DEVELOPMENT OF CANDIDATE MALARIA VACCINES
BALLOU, W. RIPLEY, AREVALO-HERRERA, MYRIAM, CARUCCI, DANIEL, RICHIE, THOMAS L, CORRADIN, GIAMPIETRO, DIGGS, CARTER, DRUILHE, PIERRE, GIERSING, BIRGITTE K, SAUL, ALLAN, HEPPNER, D. GRAY, KESTER, KENT E, LANAR, DAVID E, LYON, JEFF, HILL, ADRIAN V. S, PAN, WEIQING, COHEN, JOE D
Published in The American journal of tropical medicine and hygiene (01.08.2004)
Published in The American journal of tropical medicine and hygiene (01.08.2004)
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Journal Article
Controlled Human Infection With Bordetella pertussis Induces Asymptomatic, Immunizing Colonization
de Graaf, Hans, Ibrahim, Muktar, Hill, Alison R, Gbesemete, Diane, Vaughan, Andrew T, Gorringe, Andrew, Preston, Andrew, Buisman, Annemarie M, Faust, Saul N, Kester, Kent E, Berbers, Guy A M, Diavatopoulos, Dimitri A, Read, Robert C
Published in Clinical infectious diseases (11.07.2020)
Published in Clinical infectious diseases (11.07.2020)
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Journal Article
Characterization of potential biomarkers of reactogenicity of licensed antiviral vaccines: randomized controlled clinical trials conducted by the BIOVACSAFE consortium
Weiner, January, Lewis, David J. M., Maertzdorf, Jeroen, Mollenkopf, Hans-Joachim, Bodinham, Caroline, Pizzoferro, Kat, Linley, Catherine, Greenwood, Aldona, Mantovani, Alberto, Bottazzi, Barbara, Denoel, Philippe, Leroux-Roels, Geert, Kester, Kent E., Jonsdottir, Ingileif, van den Berg, Robert, Kaufmann, Stefan H. E., Del Giudice, Giuseppe
Published in Scientific reports (30.12.2019)
Published in Scientific reports (30.12.2019)
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Journal Article
Cholesterol-conjugated stapled peptides inhibit Ebola and Marburg viruses in vitro and in vivo
Pessi, Antonello, Bixler, Sandra L., Soloveva, Veronica, Radoshitzky, Sheli, Retterer, Cary, Kenny, Tara, Zamani, Rouzbeh, Gomba, Glenn, Gharabeih, Dima, Wells, Jay, Wetzel, Kelly S., Warren, Travis K., Donnelly, Ginger, Van Tongeren, Sean A., Steffens, Jesse, Duplantier, Allen J., Kane, Christopher D., Vicat, Pascale, Couturier, Valerie, Kester, Kent E., Shiver, John, Carter, Kara, Bavari, Sina
Published in Antiviral research (01.11.2019)
Published in Antiviral research (01.11.2019)
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Journal Article
Investigating Bordetella pertussis colonisation and immunity: protocol for an inpatient controlled human infection model
de Graaf, Hans, Gbesemete, Diane, Gorringe, Andrew R., Diavatopoulos, Dimitri A., Kester, Kent E., Faust, Saul N., Read, Robert C.
Published in BMJ open (01.10.2017)
Published in BMJ open (01.10.2017)
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Journal Article
The Antimicrobial Resistance Monitoring and Research (ARMoR) Program: The US Department of Defense Response to Escalating Antimicrobial Resistance
Lesho, Emil P., Waterman, Paige E., Chukwuma, Uzo, McAuliffe, Kathryn, Neumann, Charlotte, Julius, Michael D., Crouch, Helen, Chandrasekera, Ruvani, English, Judith F., Clifford, Robert J., Kester, Kent E.
Published in Clinical infectious diseases (01.08.2014)
Published in Clinical infectious diseases (01.08.2014)
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Journal Article
Sequential Phase 1 and Phase 2 randomized, controlled trials of the safety, immunogenicity and efficacy of combined pre-erythrocytic vaccine antigens RTS,S and TRAP formulated with AS02 Adjuvant System in healthy, malaria naïve adults
Kester, Kent E., Gray Heppner, D., Moris, Philippe, Ofori-Anyinam, Opokua, Krzych, Urszula, Tornieporth, Nadia, McKinney, Denise, Delchambre, Martine, Ockenhouse, Christian F., Voss, Gerald, Holland, Carolyn, Beckey, Jolie Palensky, Ballou, W. Ripley, Cohen, Joe
Published in Vaccine (20.11.2014)
Published in Vaccine (20.11.2014)
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Journal Article
Summit proceedings: Biomedical countermeasure development for emerging vector-borne viral diseases
Blackman, Marcia A., Marchionni, Mark A., Gilly, John, Hepburn, Matthew, Innis, Bruce L., Barrett, Alan D.T., Kester, Kent E., Mascola, John R., Cummings, James F., Monath, Thomas P., Cassetti, M. Cristina, Kim, Jerome H., Saville, Melanie, Thomas, Stephen J.
Published in Vaccine (08.10.2019)
Published in Vaccine (08.10.2019)
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Journal Article
Protective Immunity Induced with Malaria Vaccine, RTS,S, Is Linked to Plasmodium falciparum Circumsporozoite Protein-Specific CD4+ and CD8+ T Cells Producing IFN-γ
Sun, Peifang, Schwenk, Robert, White, Katherine, Stoute, Jose A., Cohen, Joe, Ballou, W. Ripley, Voss, Gerald, Kester, Kent E., Heppner, D. Gray, Krzych, Urszula
Published in The Journal of immunology (1950) (15.12.2003)
Published in The Journal of immunology (1950) (15.12.2003)
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Journal Article
Enhanced T-cell immunogenicity of plasmid DNA vaccines boosted by recombinant modified vaccinia virus Ankara in humans
McConkey, Samuel J, Reece, William H H, Moorthy, Vasee S, Webster, Daniel, Dunachie, Susanna, Butcher, Geoff, Vuola, Jenni M, Blanchard, Tom J, Gothard, Philip, Watkins, Kate, Hannan, Carolyn M, Everaere, Simone, Brown, Karen, Kester, Kent E, Cummings, James, Williams, Jackie, Heppner, D Gray, Pathan, Ansar, Flanagan, Katie, Arulanantham, Nirmalan, Roberts, Mark T M, Roy, Michael, Smith, Geoffrey L, Schneider, Joerg, Peto, Tim, Sinden, Robert E, Gilbert, Sarah C, Hill, Adrian V S
Published in Nature medicine (01.06.2003)
Published in Nature medicine (01.06.2003)
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Journal Article