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Sex-specific regulatory architecture of pancreatic islets from subjects with and without type 2 diabetes
Qadir, Mirza Muhammad Fahd, Elgamal, Ruth M, Song, Kejing, Kudtarkar, Parul, Sakamuri, Siva S V P, Katakam, Prasad V, El-Dahr, Samir S, Kolls, Jay K, Gaulton, Kyle J, Mauvais-Jarvis, Franck
Published in The EMBO journal (16.12.2024)
Published in The EMBO journal (16.12.2024)
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Journal Article
ATAC-seq reveals alterations in open chromatin in pancreatic islets from subjects with type 2 diabetes
Bysani, Madhusudhan, Agren, Rasmus, Davegårdh, Cajsa, Volkov, Petr, Rönn, Tina, Unneberg, Per, Bacos, Karl, Ling, Charlotte
Published in Scientific reports (23.05.2019)
Published in Scientific reports (23.05.2019)
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Journal Article
Altered microvasculature in pancreatic islets from subjects with type 1 diabetes
Granlund, Louise, Hedin, Anders, Korsgren, Olle, Skog, Oskar, Lundberg, Marcus
Published in PloS one (31.10.2022)
Published in PloS one (31.10.2022)
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Journal Article
Human Islets Have Fewer Blood Vessels than Mouse Islets and the Density of Islet Vascular Structures Is Increased in Type 2 Diabetes
Brissova, Marcela, Shostak, Alena, Fligner, Corinne L., Revetta, Frank L., Washington, Mary K., Powers, Alvin C., Hull, Rebecca L.
Published in The journal of histochemistry and cytochemistry (01.08.2015)
Published in The journal of histochemistry and cytochemistry (01.08.2015)
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Journal Article
Restoration of PITPNA in Type 2 diabetic human islets reverses pancreatic beta-cell dysfunction
Yeh, Yu-Te, Sona, Chandan, Yan, Xin, Li, Yunxiao, Pathak, Adrija, McDermott, Mark I., Xie, Zhigang, Liu, Liangwen, Arunagiri, Anoop, Wang, Yuting, Cazenave-Gassiot, Amaury, Ghosh, Adhideb, von Meyenn, Ferdinand, Kumarasamy, Sivarajan, Najjar, Sonia M., Jia, Shiqi, Wenk, Markus R., Traynor-Kaplan, Alexis, Arvan, Peter, Barg, Sebastian, Bankaitis, Vytas A., Poy, Matthew N.
Published in Nature communications (17.07.2023)
Published in Nature communications (17.07.2023)
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Journal Article
Phase 3 Trial of Transplantation of Human Islets in Type 1 Diabetes Complicated by Severe Hypoglycemia
Hering, Bernhard J., Clarke, William R., Bridges, Nancy D., Eggerman, Thomas L., Alejandro, Rodolfo, Bellin, Melena D., Chaloner, Kathryn, Czarniecki, Christine W., Goldstein, Julia S., Hunsicker, Lawrence G., Kaufman, Dixon B., Korsgren, Olle, Larsen, Christian P., Luo, Xunrong, Markmann, James F., Naji, Ali, Oberholzer, Jose, Posselt, Andrew M., Rickels, Michael R., Ricordi, Camillo, Robien, Mark A., Senior, Peter A., Shapiro, A.M. James, Stock, Peter G., Turgeon, Nicole A.
Published in Diabetes care (01.07.2016)
Published in Diabetes care (01.07.2016)
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Journal Article
IL-6 is present in beta and alpha cells in human pancreatic islets: Expression is reduced in subjects with type 1 diabetes
Rajendran, Sakthi, Anquetil, Florence, Quesada-Masachs, Estefania, Graef, Madeleine, Gonzalez, Nathaly, McArdle, Sara, Chu, Tiffany, Krogvold, Lars, Dahl-Jørgensen, Knut, von Herrath, Matthias
Published in Clinical immunology (Orlando, Fla.) (01.02.2020)
Published in Clinical immunology (Orlando, Fla.) (01.02.2020)
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Journal Article
2094-P: Effects of Irisin on Human Pancreatic Islets from Type 2 Diabetic Subjects
MARRANO, NICOLA, NATALICCHIO, ANNALISA, BIONDI, GIUSEPPINA, CIGNARELLI, ANGELO, VINCENTI, LEONARDO, LUPO, LUIGI G., PERRINI, SEBASTIO, LAVIOLA, LUIGI, GIORGINO, FRANCESCO
Published in Diabetes (New York, N.Y.) (01.06.2020)
Published in Diabetes (New York, N.Y.) (01.06.2020)
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Journal Article
prevalence of enteroviral capsid protein vp1 immunostaining in pancreatic islets in human type 1 diabetes
Richardson, S. J, Willcox, A, Bone, A. J, Foulis, A. K, Morgan, N. G
Published in Diabetologia (01.06.2009)
Published in Diabetologia (01.06.2009)
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Journal Article
Structural and Functional Abnormalities in the Islets Isolated From Type 2 Diabetic Subjects
Deng, Shaoping, Vatamaniuk, Marko, Huang, Xiaolun, Doliba, Nicolai, Lian, Moh-Moh, Frank, Adam, Velidedeoglu, Ergun, Desai, Niraj M., Koeberlein, Brigitte, Wolf, Bryan, Barker, Clyde F., Naji, Ali, Matschinsky, Franz M., Markmann, James F.
Published in Diabetes (New York, N.Y.) (01.03.2004)
Published in Diabetes (New York, N.Y.) (01.03.2004)
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Journal Article
Dipeptidyl peptidase 4 (DPP-4) is expressed in mouse and human islets and its activity is decreased in human islets from individuals with type 2 diabetes
Omar, Bilal A., Liehua, Liu, Yamada, Yuchiro, Seino, Yutaka, Marchetti, Piero, Ahrén, B.
Published in Diabetologia (01.09.2014)
Published in Diabetologia (01.09.2014)
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Journal Article
Autoreactive CD8+ T cell exhaustion distinguishes subjects with slow type 1 diabetes progression
Wiedeman, Alice E., Muir, Virginia S., Rosasco, Mario G., DeBerg, Hannah A., Presnell, Scott, Haas, Bertrand, Dufort, Matthew J., Speake, Cate, Greenbaum, Carla J., Serti, Elisavet, Nepom, Gerald T., Blahnik, Gabriele, Kus, Anna M., James, Eddie A., Linsley, Peter S., Long, S. Alice
Published in The Journal of clinical investigation (02.01.2020)
Published in The Journal of clinical investigation (02.01.2020)
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Journal Article
The diet‐derived short chain fatty acid propionate improves beta‐cell function in humans and stimulates insulin secretion from human islets in vitro
Pingitore, Attilio, Chambers, Edward S., Hill, Thomas, Maldonado, Inmaculada Ruz, Liu, Bo, Bewick, Gavin, Morrison, Douglas J., Preston, Tom, Wallis, Gareth A., Tedford, Catriona, Castañera González, Ramón, Huang, Guo C., Choudhary, Pratik, Frost, Gary, Persaud, Shanta J.
Published in Diabetes, obesity & metabolism (01.02.2017)
Published in Diabetes, obesity & metabolism (01.02.2017)
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Journal Article
Ghrelin suppresses insulin secretion in human islets and type 2 diabetes patients have diminished islet ghrelin cell number and lower plasma ghrelin levels
Lindqvist, A., Shcherbina, L., Prasad, R.B., Miskelly, M.G., Abels, M., Martínez-Lopéz, J.A., Fred, R.G., Nergård, B.J., Hedenbro, J., Groop, L., Hjerling-Leffler, J., Wierup, N.
Published in Molecular and cellular endocrinology (01.07.2020)
Published in Molecular and cellular endocrinology (01.07.2020)
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Journal Article
Inflammatory Cell Infiltration Into Islets Without PD-L1 Expression Is Associated With the Development of Immune Checkpoint Inhibitor–Related Type 1 Diabetes in Genetically Susceptible Patients
Kawata, Satoshi, Kozawa, Junji, Yoneda, Sho, Fujita, Yukari, Kashiwagi-Takayama, Risa, Kimura, Takekazu, Hosokawa, Yoshiya, Baden, Megu Y., Uno, Sae, Uenaka, Rikako, Namai, Kazuyuki, Koh, Yoko, Tomimaru, Yoshito, Hirata, Haruhiko, Uemura, Motohide, Nojima, Satoshi, Morii, Eiichi, Eguchi, Hidetoshi, Imagawa, Akihisa, Shimomura, Iichiro
Published in Diabetes (New York, N.Y.) (01.04.2023)
Published in Diabetes (New York, N.Y.) (01.04.2023)
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Journal Article
Proinsulin-Specific, HLA-DQ8, and HLA-DQ8-Transdimer–Restricted CD4+ T Cells Infiltrate Islets in Type 1 Diabetes
Pathiraja, Vimukthi, Kuehlich, Janine P., Campbell, Peter D., Krishnamurthy, Balasubramanian, Loudovaris, Thomas, Coates, P. Toby H., Brodnicki, Thomas C., O’Connell, Philip J., Kedzierska, Katherine, Rodda, Christine, Bergman, Philip, Hill, Erin, Purcell, Anthony W., Dudek, Nadine L., Thomas, Helen E., Kay, Thomas W.H., Mannering, Stuart I.
Published in Diabetes (New York, N.Y.) (01.01.2015)
Published in Diabetes (New York, N.Y.) (01.01.2015)
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Journal Article
Bulk tissue cell type deconvolution with multi-subject single-cell expression reference
Wang, Xuran, Park, Jihwan, Susztak, Katalin, Zhang, Nancy R., Li, Mingyao
Published in Nature communications (22.01.2019)
Published in Nature communications (22.01.2019)
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Journal Article
High Glucose Represses β-Klotho Expression and Impairs Fibroblast Growth Factor 21 Action in Mouse Pancreatic Islets: Involvement of Peroxisome Proliferator-Activated Receptor γ Signaling
WING YAN SO, QIANNI CHENG, LIHUA CHEN, EVANS-MOLINA, Carmella, AIMIN XU, LAM, Karen S. L, PO SING LEUNG
Published in Diabetes (New York, N.Y.) (01.11.2013)
Published in Diabetes (New York, N.Y.) (01.11.2013)
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Journal Article