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Management of Venetoclax-Posaconazole Interaction in Acute Myeloid Leukemia Patients: Evaluation of Dose Adjustments
Agarwal, Suresh K., DiNardo, Courtney D., Potluri, Jalaja, Dunbar, Martin, Kantarjian, Hagop M., Humerickhouse, Rod A., Wong, Shekman L., Menon, Rajeev M., Konopleva, Marina Y., Salem, Ahmed Hamed
Published in Clinical therapeutics (01.02.2017)
Published in Clinical therapeutics (01.02.2017)
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Journal Article
Venetoclax for chronic lymphocytic leukaemia progressing after ibrutinib: an interim analysis of a multicentre, open-label, phase 2 trial
Jones, Jeffrey A, Mato, Anthony R, Wierda, William G, Davids, Matthew S, Choi, Michael, Cheson, Bruce D, Furman, Richard R, Lamanna, Nicole, Barr, Paul M, Zhou, Lang, Chyla, Brenda, Salem, Ahmed Hamed, Verdugo, Maria, Humerickhouse, Rod A, Potluri, Jalaja, Coutre, Steven, Woyach, Jennifer, Byrd, John C
Published in The lancet oncology (01.01.2018)
Published in The lancet oncology (01.01.2018)
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Journal Article
Navitoclax, a targeted high-affinity inhibitor of BCL-2, in lymphoid malignancies: a phase 1 dose-escalation study of safety, pharmacokinetics, pharmacodynamics, and antitumour activity
Wilson, Wyndham H, O'Connor, Owen A, Czuczman, Myron S, LaCasce, Ann S, Gerecitano, John F, Leonard, John P, Tulpule, Anil, Dunleavy, Kieron, Xiong, Hao, Chiu, Yi-Lin, Cui, Yue, Busman, Todd, Elmore, Steven W, Rosenberg, Saul H, Krivoshik, Andrew P, Enschede, Sari H, Humerickhouse, Rod A
Published in The lancet oncology (01.12.2010)
Published in The lancet oncology (01.12.2010)
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Journal Article
Venetoclax plus rituximab in relapsed or refractory chronic lymphocytic leukaemia: a phase 1b study
Seymour, John F, Ma, Shuo, Brander, Danielle M, Choi, Michael Y, Barrientos, Jacqueline, Davids, Matthew S, Anderson, Mary Ann, Beaven, Anne W, Rosen, Steven T, Tam, Constantine S, Prine, Betty, Agarwal, Suresh K, Munasinghe, Wijith, Zhu, Ming, Lash, L Leanne, Desai, Monali, Cerri, Elisa, Verdugo, Maria, Kim, Su Young, Humerickhouse, Rod A, Gordon, Gary B, Kipps, Thomas J, Roberts, Andrew W
Published in The lancet oncology (01.02.2017)
Published in The lancet oncology (01.02.2017)
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Journal Article
Utility of positron emission tomography-computed tomography in patients with chronic lymphocytic leukemia following B-cell receptor pathway inhibitor therapy
Mato, Anthony R., Wierda, William G., Davids, Matthew S., Cheson, Bruce D., Coutre, Steven E., Choi, Michael, Furman, Richard R., Heffner, Leonard, Barr, Paul M., Eradat, Herbert, Ford, Sharanya M., Zhou, Lang, Verdugo, Maria, Humerickhouse, Rod A., Potluri, Jalaja, Byrd, John C.
Published in Haematologica (Roma) (01.11.2019)
Published in Haematologica (Roma) (01.11.2019)
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Journal Article
Effect of Endothelin-A Receptor Blockade With Atrasentan on Tumor Progression in Men With Hormone-Refractory Prostate Cancer: A Randomized, Phase II, Placebo-Controlled Trial
Carducci, Michael A., Padley, Robert J., Breul, Jurgen, Vogelzang, Nicholas J., Zonnenberg, Bernard A., Daliani, Danai D., Schulman, Claude C., Nabulsi, Azmi A., Humerickhouse, Rod A., Weinberg, Mark A., Schmitt, Jennifer L., Nelson, Joel B.
Published in Journal of clinical oncology (15.02.2003)
Published in Journal of clinical oncology (15.02.2003)
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Journal Article
Randomized, Phase II Study of the Thrombospondin-1-Mimetic Angiogenesis Inhibitor ABT-510 in Patients With Advanced Soft Tissue Sarcoma
Baker, Laurence H., Rowinsky, Eric K., Mendelson, David, Humerickhouse, Rod A., Knight, Raymond A., Qian, Jiang, Carr, Robert A., Gordon, Gary B., Demetri, George D.
Published in Journal of clinical oncology (01.12.2008)
Published in Journal of clinical oncology (01.12.2008)
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Journal Article
Phase 2 Study of ABT-510 in Patients with Previously Untreated Advanced Renal Cell Carcinoma
Ebbinghaus, Scot, Hussain, Maha, Tannir, Nizar, Gordon, Michael, Desai, Apurva A., Knight, Raymond A., Humerickhouse, Rod A., Qian, Jiang, Gordon, Gary B., Figlin, Robert
Published in Clinical cancer research (15.11.2007)
Published in Clinical cancer research (15.11.2007)
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Journal Article
Targeting BCL2 with Venetoclax in Relapsed Chronic Lymphocytic Leukemia
Roberts, Andrew W, Davids, Matthew S, Pagel, John M, Kahl, Brad S, Puvvada, Soham D, Gerecitano, John F, Kipps, Thomas J, Anderson, Mary Ann, Brown, Jennifer R, Gressick, Lori, Wong, Shekman, Dunbar, Martin, Zhu, Ming, Desai, Monali B, Cerri, Elisa, Heitner Enschede, Sari, Humerickhouse, Rod A, Wierda, William G, Seymour, John F
Published in The New England journal of medicine (28.01.2016)
Published in The New England journal of medicine (28.01.2016)
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Journal Article
Phase I First-in-Human Study of Venetoclax in Patients With Relapsed or Refractory Non-Hodgkin Lymphoma
Davids, Matthew S., Roberts, Andrew W., Seymour, John F., Pagel, John M., Kahl, Brad S., Wierda, William G., Puvvada, Soham, Kipps, Thomas J., Anderson, Mary Ann, Salem, Ahmed Hamed, Dunbar, Martin, Zhu, Ming, Peale, Franklin, Ross, Jeremy A., Gressick, Lori, Desai, Monali, Kim, Su Young, Verdugo, Maria, Humerickhouse, Rod A., Gordon, Gary B., Gerecitano, John F.
Published in Journal of clinical oncology (10.03.2017)
Published in Journal of clinical oncology (10.03.2017)
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Journal Article
Venetoclax for patients with chronic lymphocytic leukemia who progressed during or after idelalisib therapy
Coutre, Steven, Choi, Michael, Furman, Richard R., Eradat, Herbert, Heffner, Leonard, Jones, Jeffrey A., Chyla, Brenda, Zhou, Lang, Agarwal, Suresh, Waskiewicz, Tina, Verdugo, Maria, Humerickhouse, Rod A., Potluri, Jalaja, Wierda, William G., Davids, Matthew S.
Published in Blood (12.04.2018)
Published in Blood (12.04.2018)
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Journal Article
ABT-199, a potent and selective BCL-2 inhibitor, achieves antitumor activity while sparing platelets
Souers, Andrew J, Leverson, Joel D, Boghaert, Erwin R, Ackler, Scott L, Catron, Nathaniel D, Chen, Jun, Dayton, Brian D, Ding, Hong, Enschede, Sari H, Fairbrother, Wayne J, Huang, David C S, Hymowitz, Sarah G, Jin, Sha, Khaw, Seong Lin, Kovar, Peter J, Lam, Lloyd T, Lee, Jackie, Maecker, Heather L, Marsh, Kennan C, Mason, Kylie D, Mitten, Michael J, Nimmer, Paul M, Oleksijew, Anatol, Park, Chang H, Park, Cheol-Min, Phillips, Darren C, Roberts, Andrew W, Sampath, Deepak, Seymour, John F, Smith, Morey L, Sullivan, Gerard M, Tahir, Stephen K, Tse, Chris, Wendt, Michael D, Xiao, Yu, Xue, John C, Zhang, Haichao, Humerickhouse, Rod A, Rosenberg, Saul H, Elmore, Steven W
Published in Nature medicine (01.02.2013)
Published in Nature medicine (01.02.2013)
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Journal Article
Phase I Safety, Pharmacokinetic, and Pharmacodynamic Study of the Thrombospondin-1–Mimetic Angiogenesis Inhibitor ABT-510 in Patients With Advanced Cancer
Hoekstra, Ronald, de Vos, Filip Y.F.L., Eskens, Ferry A.L.M., Gietema, Jourik A., van der Gaast, Ate, Groen, Harry J.M., Knight, Raymond A., Carr, Robert A., Humerickhouse, Rod A., Verweij, Jaap, de Vries, Elisabeth G.E.
Published in Journal of clinical oncology (01.08.2005)
Published in Journal of clinical oncology (01.08.2005)
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Journal Article
Phase II Study of Single-Agent Navitoclax (ABT-263) and Biomarker Correlates in Patients with Relapsed Small Cell Lung Cancer
Rudin, Charles M., Hann, Christine L., Garon, Edward B., Ribeiro de Oliveira, Moacyr, Bonomi, Philip D., Camidge, D. Ross, Chu, Quincy, Giaccone, Giuseppe, Khaira, Divis, Ramalingam, Suresh S., Ranson, Malcolm R., Dive, Caroline, McKeegan, Evelyn M., Chyla, Brenda J., Dowell, Barry L., Chakravartty, Arunava, Nolan, Cathy E., Rudersdorf, Niki, Busman, Todd A., Mabry, Mack H., Krivoshik, Andrew P., Humerickhouse, Rod A., Shapiro, Geoffrey I., Gandhi, Leena
Published in Clinical cancer research (01.06.2012)
Published in Clinical cancer research (01.06.2012)
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Journal Article
Clinical Predictors of Venetoclax Pharmacokinetics in Chronic Lymphocytic Leukemia and Non-Hodgkin’s Lymphoma Patients: a Pooled Population Pharmacokinetic Analysis
Jones, Aksana K., Freise, Kevin J., Agarwal, Suresh K., Humerickhouse, Rod A., Wong, Shekman L., Salem, Ahmed Hamed
Published in The AAPS journal (01.09.2016)
Published in The AAPS journal (01.09.2016)
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Journal Article
Impact of Venetoclax Exposure on Clinical Efficacy and Safety in Patients with Relapsed or Refractory Chronic Lymphocytic Leukemia
Freise, Kevin J., Jones, Aksana K., Eckert, Doerthe, Mensing, Sven, Wong, Shekman L., Humerickhouse, Rod A., Awni, Walid M., Salem, Ahmed Hamed
Published in Clinical pharmacokinetics (01.05.2017)
Published in Clinical pharmacokinetics (01.05.2017)
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Journal Article
Revised Dose Ramp-Up to Mitigate the Risk of Tumor Lysis Syndrome When Initiating Venetoclax in Patients With Mantle Cell Lymphoma
Davids, Matthew S., von Keudell, Gottfried, Portell, Craig A., Cohen, Jonathon B., Fisher, David C., Foss, Francine, Roberts, Andrew W., Seymour, John F., Humerickhouse, Rod A., Tam, Constantine S.
Published in Journal of clinical oncology (10.12.2018)
Published in Journal of clinical oncology (10.12.2018)
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Journal Article
Relationship between venetoclax exposure, rituximab coadministration, and progression‐free survival in patients with relapsed or refractory chronic lymphocytic leukemia: demonstration of synergy
Freise, Kevin J., Jones, Aksana K., Menon, Rajeev M., Verdugo, Maria E., Humerickhouse, Rod A., Awni, Walid M., Salem, Ahmed Hamed
Published in Hematological oncology (01.12.2017)
Published in Hematological oncology (01.12.2017)
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Journal Article
A phase 1 trial of 2 dose schedules of ABT‐510, an antiangiogenic, thrombospondin‐1‐mimetic peptide, in patients with advanced cancer
Gordon, Michael S., Mendelson, David, Carr, Robert, Knight, Raymond A., Humerickhouse, Rod A., Iannone, Maria, Stopeck, Alison T.
Published in Cancer (15.12.2008)
Published in Cancer (15.12.2008)
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Journal Article
A comparative study of dynamic contrast-enhanced MRI parameters as biomarkers for anti-angiogenic drug therapy
Koh, Tong San, Thng, Choon Hua, Hartono, Septian, Tai, Bee Choo, Rumpel, Helmut, Ong, Ai Bee, Sukri, Norita, Soo, Ross A., Wong, Chuing Ing, Low, Albert S. C., Humerickhouse, Rod A., Goh, Boon Cher
Published in NMR in biomedicine (01.11.2011)
Published in NMR in biomedicine (01.11.2011)
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Journal Article