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Early antiretroviral therapy limits SIV reservoir establishment to delay or prevent post-treatment viral rebound
Okoye, Afam A, Hansen, Scott G, Vaidya, Mukta, Fukazawa, Yoshinori, Park, Haesun, Duell, Derick M, Lum, Richard, Hughes, Colette M, Ventura, Abigail B, Ainslie, Emily, d, Julia C, Morrow, David, Gilbride, Roxanne M, Legasse, Alfred W, Hesselgesser, Joseph, Geleziunas, Romas, Li, Yuan, Oswald, Kelli, Shoemaker, Rebecca, Fast, Randy, Bosche, William J, Borate, Bhavesh R, Edlefsen, Paul T, Axthelm, Michael K, Picker, Louis J, Lifson, Jeffrey D
Published in Nature medicine (01.09.2018)
Published in Nature medicine (01.09.2018)
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Journal Article
Cytomegalovirus vaccine vector-induced effector memory CD4 + T cells protect cynomolgus macaques from lethal aerosolized heterologous avian influenza challenge
Malouli, Daniel, Tiwary, Meenakshi, Gilbride, Roxanne M., Morrow, David W., Hughes, Colette M., Selseth, Andrea, Penney, Toni, Castanha, Priscila, Wallace, Megan, Yeung, Yulia, Midgett, Morgan, Williams, Connor, Reed, Jason, Yu, Yun, Gao, Lina, Yun, Gabin, Treaster, Luke, Laughlin, Amanda, Lundy, Jeneveve, Tisoncik-Go, Jennifer, Whitmore, Leanne S., Aye, Pyone P., Schiro, Faith, Dufour, Jason P., Papen, Courtney R., Taher, Husam, Picker, Louis J., Früh, Klaus, Gale, Michael, Maness, Nicholas J., Hansen, Scott G., Barratt-Boyes, Simon, Reed, Douglas S., Sacha, Jonah B.
Published in Nature communications (19.07.2024)
Published in Nature communications (19.07.2024)
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Journal Article
Viral escape mutations do not account for non-protection from SIVmac239 challenge in RhCMV/SIV vaccinated rhesus macaques
Bimber, Benjamin N., Sunshine, Justine, McElfresh, G. W., Reed, Jason S., Pathak, Reese, Bateman, Katherine B., Hughes, Colette M., Gilbride, Roxanne M., Ford, Julia C., Morrow, David, Lifson, Jeffrey D., Sacha, Jonah B., Hansen, Scott G., Picker, Louis J.
Published in Frontiers in immunology (07.08.2024)
Published in Frontiers in immunology (07.08.2024)
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Journal Article
Late gene expression–deficient cytomegalovirus vectors elicit conventional T cells that do not protect against SIV
Hansen, Scott G., Womack, Jennie L., Perez, Wilma, Schmidt, Kimberli A., Marshall, Emily, Iyer, Ravi F., Cleveland Rubeor, Hillary, Otero, Claire E., Taher, Husam, Vande Burgt, Nathan H., Barfield, Richard, Randall, Kurt T., Morrow, David, Hughes, Colette M., Selseth, Andrea N., Gilbride, Roxanne M., Ford, Julia C., Caposio, Patrizia, Tarantal, Alice F., Chan, Cliburn, Malouli, Daniel, Barry, Peter A., Permar, Sallie R., Picker, Louis J., Früh, Klaus
Published in JCI insight (22.03.2023)
Published in JCI insight (22.03.2023)
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Journal Article
Profound early control of highly pathogenic SIV by an effector memory T-cell vaccine
Hansen, Scott G., Ford, Julia C., Lewis, Matthew S., Ventura, Abigail B., Hughes, Colette M., Coyne-Johnson, Lia, Whizin, Nathan, Oswald, Kelli, Shoemaker, Rebecca, Swanson, Tonya, Legasse, Alfred W., Chiuchiolo, Maria J., Parks, Christopher L., Axthelm, Michael K., Nelson, Jay A., Jarvis, Michael A., Piatak, Michael, Lifson, Jeffrey D., Picker, Louis J.
Published in Nature (London) (26.05.2011)
Published in Nature (London) (26.05.2011)
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Journal Article
Prevention of tuberculosis in rhesus macaques by a cytomegalovirus-based vaccine
Hansen, Scott G, Zak, Daniel E, Xu, Guangwu, d, Julia C, Marshall, Emily E, Malouli, Daniel, Gilbride, Roxanne M, Hughes, Colette M, Ventura, Abigail B, Ainslie, Emily, Randall, Kurt T, Selseth, Andrea N, Rundstrom, Parker, Herlache, Lauren, Lewis, Matthew S, Park, Haesun, Planer, Shannon L, Turner, John M, Fischer, Miranda, Armstrong, Christina, Zweig, Robert C, Valvo, Joseph, Braun, Jackie M, Shankar, Smitha, Lu, Lenette, Sylwester, Andrew W, Legasse, Alfred W, Messerle, Martin, Jarvis, Michael A, Amon, Lynn M, Aderem, Alan, Alter, Galit, Laddy, Dominick J, Stone, Michele, Bonavia, Aurelio, Evans, Thomas G, Axthelm, Michael K, Früh, Klaus, Edlefsen, Paul T, Picker, Louis J
Published in Nature medicine (01.02.2018)
Published in Nature medicine (01.02.2018)
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Journal Article
Immune clearance of highly pathogenic SIV infection
Hansen, Scott G., Jr, Michael Piatak, Ventura, Abigail B., Hughes, Colette M., Gilbride, Roxanne M., Ford, Julia C., Oswald, Kelli, Shoemaker, Rebecca, Li, Yuan, Lewis, Matthew S., Gilliam, Awbrey N., Xu, Guangwu, Whizin, Nathan, Burwitz, Benjamin J., Planer, Shannon L., Turner, John M., Legasse, Alfred W., Axthelm, Michael K., Nelson, Jay A., Früh, Klaus, Sacha, Jonah B., Estes, Jacob D., Keele, Brandon F., Edlefsen, Paul T., Lifson, Jeffrey D., Picker, Louis J.
Published in Nature (London) (03.10.2013)
Published in Nature (London) (03.10.2013)
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Journal Article
Cytomegalovirus Vectors Violate CD8⁺ T Cell Epitope Recognition Paradigms
Hansen, Scott G., Sacha, Jonah B., Hughes, Colette M., Ford, Julia C., Burwitz, Benjamin J., Scholz, Isabel, Gilbride, Roxanne M., Lewis, Matthew S., Gilliam, Awbrey N., Ventura, Abigail B., Malouli, Daniel, Xu, Guangwu, Richards, Rebecca, Whizin, Nathan, Reed, Jason S., Hammond, Katherine B., Fischer, Miranda, Turner, John M., Legasse, Alfred W., Axthelm, Michael K., Edlefsen, Paul T., Nelson, Jay A., Lifson, Jeffrey D., Früh, Klaus, Picker, Louis J.
Published in Science (American Association for the Advancement of Science) (24.05.2013)
Published in Science (American Association for the Advancement of Science) (24.05.2013)
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Journal Article
Modulation of MHC-E transport by viral decoy ligands is required for RhCMV/SIV vaccine efficacy
Verweij, Marieke C., Hansen, Scott G., Iyer, Ravi, John, Nessy, Malouli, Daniel, Morrow, David, Scholz, Isabel, Womack, Jennie, Abdulhaqq, Shaheed, Gilbride, Roxanne M., Hughes, Colette M., Ventura, Abigail B., Ford, Julia C., Selseth, Andrea N., Oswald, Kelli, Shoemaker, Rebecca, Berkemeier, Brian, Bosche, William J., Hull, Michael, Shao, Jason, Sacha, Jonah B., Axthelm, Michael K., Edlefsen, Paul T., Lifson, Jeffrey D., Picker, Louis J., Früh, Klaus
Published in Science (American Association for the Advancement of Science) (30.04.2021)
Published in Science (American Association for the Advancement of Science) (30.04.2021)
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Journal Article
Glycoprotein L–deleted single-cycle rhesus cytomegalovirus vectors elicit MHC-E–restricted CD8+ T cells that protect against SIV
Hansen, Scott G, Schell, John B, Marshall, Emily E, Ojha, Sohita, Feltham, Shana, Morrow, David, Hughes, Colette M, Gilbride, Roxanne M, Ford, Julia C, Cleveland-Rubeor, Hilary C, McArdle, Matthew R, Whitmer, Travis, Barber-Axthelm, Aaron, Bochart, Rachelle, Smedley, Jeremy, Oswald, Kelli, Fast, Randy, Shoemaker, Rebecca, Kosmider, Ewelina, Edlefsen, Paul T, Lifson, Jeffrey D, Malouli, Daniel, Früh, Klaus, Picker, Louis J
Published in The Journal of immunology (1950) (01.08.2025)
Published in The Journal of immunology (1950) (01.08.2025)
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Journal Article
Cytomegalovirus-vaccine-induced unconventional T cell priming and control of SIV replication is conserved between primate species
Malouli, Daniel, Gilbride, Roxanne M., Wu, Helen L., Hwang, Joseph M., Maier, Nicholas, Hughes, Colette M., Newhouse, Daniel, Morrow, David, Ventura, Abigail B., Law, Lynn, Tisoncik-Go, Jennifer, Whitmore, Leanne, Smith, Elise, Golez, Inah, Chang, Jean, Reed, Jason S., Waytashek, Courtney, Weber, Whitney, Taher, Husam, Uebelhoer, Luke S., Womack, Jennie L., McArdle, Matthew R., Gao, Junwei, Papen, Courtney R., Lifson, Jeffrey D., Burwitz, Benjamin J., Axthelm, Michael K., Smedley, Jeremy, Früh, Klaus, Gale, Michael, Picker, Louis J., Hansen, Scott G., Sacha, Jonah B.
Published in Cell host & microbe (14.09.2022)
Published in Cell host & microbe (14.09.2022)
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Journal Article
Characterization of a live-attenuated HCMV-based vaccine platform
Caposio, Patrizia, van den Worm, Sjoerd, Crawford, Lindsey, Perez, Wilma, Kreklywich, Craig, Gilbride, Roxanne M., Hughes, Colette M., Ventura, Abigail B., Ratts, Robert, Marshall, Emily E., Malouli, Daniel, Axthelm, Michael K., Streblow, Daniel, Nelson, Jay A., Picker, Louis J., Hansen, Scott G., Früh, Klaus
Published in Scientific reports (17.12.2019)
Published in Scientific reports (17.12.2019)
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Journal Article
Interleukin-15 response signature predicts RhCMV/SIV vaccine efficacy
Barrenäs, Fredrik, Hansen, Scott G., Law, Lynn, Driscoll, Connor, Green, Richard R., Smith, Elise, Chang, Jean, Golez, Inah, Urion, Taryn, Peng, Xinxia, Whitmore, Leanne, Newhouse, Daniel, Hughes, Colette M., Morrow, David, Randall, Kurt T., Selseth, Andrea N., Ford, Julia C., Gilbride, Roxanne M., Randall, Bryan E., Ainslie, Emily, Oswald, Kelli, Shoemaker, Rebecca, Fast, Randy, Bosche, William J., Axthelm, Michael K., Fukazawa, Yoshinori, Pavlakis, George N., Felber, Barbara K., Fourati, Slim, Sekaly, Rafick-Pierre, Lifson, Jeffrey D., Komorowski, Jan, Kosmider, Ewelina, Shao, Danica, Song, Wenjun, Edlefsen, Paul T., Picker, Louis J., Gale, Michael
Published in PLoS pathogens (01.07.2021)
Published in PLoS pathogens (01.07.2021)
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Journal Article
In vitro and in vivo characterization of a recombinant rhesus cytomegalovirus containing a complete genome
Taher, Husam, Mahyari, Eisa, Kreklywich, Craig, Uebelhoer, Luke S., McArdle, Matthew R., Moström, Matilda J., Bhusari, Amruta, Nekorchuk, Michael, E, Xiaofei, Whitmer, Travis, Scheef, Elizabeth A., Sprehe, Lesli M., Roberts, Dawn L., Hughes, Colette M., Jackson, Kerianne A., Selseth, Andrea N., Ventura, Abigail B., Cleveland-Rubeor, Hillary C., Yue, Yujuan, Schmidt, Kimberli A., Shao, Jason, Edlefsen, Paul T., Smedley, Jeremy, Kowalik, Timothy F., Stanton, Richard J., Axthelm, Michael K., Estes, Jacob D., Hansen, Scott G., Kaur, Amitinder, Barry, Peter A., Bimber, Benjamin N., Picker, Louis J., Streblow, Daniel N., Früh, Klaus, Malouli, Daniel
Published in PLoS pathogens (24.11.2020)
Published in PLoS pathogens (24.11.2020)
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Journal Article
The Role of MHC-E in T Cell Immunity Is Conserved among Humans, Rhesus Macaques, and Cynomolgus Macaques
Wu, Helen L, Wiseman, Roger W, Hughes, Colette M, Webb, Gabriela M, Abdulhaqq, Shaheed A, Bimber, Benjamin N, Hammond, Katherine B, Reed, Jason S, Gao, Lina, Burwitz, Benjamin J, Greene, Justin M, Ferrer, Fidel, Legasse, Alfred W, Axthelm, Michael K, Park, Byung S, Brackenridge, Simon, Maness, Nicholas J, McMichael, Andrew J, Picker, Louis J, O’Connor, David H, Hansen, Scott G, Sacha, Jonah B
Published in The Journal of immunology (1950) (01.01.2018)
Published in The Journal of immunology (1950) (01.01.2018)
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Journal Article
Cytomegalovirus pp65 limits dissemination but is dispensable for persistence
Malouli, Daniel, Hansen, Scott G., Nakayasu, Ernesto S., Marshall, Emily E., Hughes, Colette M., Ventura, Abigail B., Gilbride, Roxanne M., Lewis, Matthew S., Xu, Guangwu, Kreklywich, Craig, Whizin, Nathan, Fischer, Miranda, Legasse, Alfred W., Viswanathan, Kasinath, Siess, Don, Camp, David G., Axthelm, Michael K., Kahl, Christoph, DeFilippis, Victor R., Smith, Richard D., Streblow, Daniel N., Picker, Louis J., Früh, Klaus
Published in The Journal of clinical investigation (01.05.2014)
Published in The Journal of clinical investigation (01.05.2014)
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Journal Article
Addendum: Immune clearance of highly pathogenic SIV infection
Hansen, Scott G., Piatak, Michael, Ventura, Abigail B., Hughes, Colette M., Gilbride, Roxanne M., Ford, Julia C., Oswald, Kelli, Shoemaker, Rebecca, Li, Yuan, Lewis, Matthew S., Gilliam, Awbrey N., Xu, Guangwu, Whizin, Nathan, Burwitz, Benjamin J., Planer, Shannon L., Turner, John M., Legasse, Alfred W., Axthelm, Michael K., Nelson, Jay A., Früh, Klaus, Sacha, Jonah B., Estes, Jacob D., Keele, Brandon F., Edlefsen, Paul T., Lifson, Jeffrey D., Picker, Louis J.
Published in Nature (London) (06.07.2017)
Published in Nature (London) (06.07.2017)
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Journal Article
Correction: Corrigendum: Immune clearance of highly pathogenic SIV infection
Hansen, Scott G., Piatak, Michael, Ventura, Abigail B., Hughes, Colette M., Gilbride, Roxanne M., Ford, Julia C., Oswald, Kelli, Shoemaker, Rebecca, Li, Yuan, Lewis, Matthew S., Gilliam, Awbrey N., Xu, Guangwu, Whizin, Nathan, Burwitz, Benjamin J., Planer, Shannon L., Turner, John M., Legasse, Alfred W., Axthelm, Michael K., Nelson, Jay A., Früh, Klaus, Sacha, Jonah B., Estes, Jacob D., Keele, Brandon F., Edlefsen, Paul T., Lifson, Jeffrey D., Picker, Louis J.
Published in Nature (London) (30.10.2014)
Published in Nature (London) (30.10.2014)
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Journal Article
Broadly targeted CD8⁺ T cell responses restricted by major histocompatibility complex E
Hansen, Scott G., Wu, Helen L., Burwitz, Benjamin J., Hughes, Colette M., Hammond, Katherine B., Ventura, Abigail B., Reed, Jason S., Gilbride, Roxanne M., Ainslie, Emily, Morrow, David W., Ford, Julia C., Selseth, Andrea N., Pathak, Reesab, Malouli, Daniel, Legasse, Alfred W., Axthelm, Michael K., Nelson, Jay A., Gillespie, Geraldine M., Walters, Lucy C., Brackenridge, Simon, Sharpe, Hannah R., López, César A., Früh, Klaus, Korber, Bette T., McMichael, Andrew J., Gnanakaran, S., Sacha, Jonah B., Picker, Louis J.
Published in Science (American Association for the Advancement of Science) (12.02.2016)
Published in Science (American Association for the Advancement of Science) (12.02.2016)
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Journal Article
T cell programming by the cytomegalovirus MHC class I homologue UL18
Taher, Husam, Malouli, Daniel, Hansen, Scott G., Mansouri, Mandana, Iyer, Ravi, Papen, Courtney, Schell, John B., Cleveland-Rubeor, Hillary, McArdle, Matthew R., Hughes, Colette M., Randall, Kurt T., McNett, Alisha, Picker, Louis J., Früh, Klaus
Published in The Journal of immunology (1950) (01.05.2022)
Published in The Journal of immunology (1950) (01.05.2022)
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Journal Article