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The Genetic Landscape and Clonal Evolution of Breast Cancer Resistance to Palbociclib plus Fulvestrant in the PALOMA-3 Trial
O'Leary, Ben, Cutts, Rosalind J., Liu, Yuan, Hrebien, Sarah, Huang, Xin, Fenwick, Kerry, André, Fabrice, Loibl, Sibylle, Loi, Sherene, Garcia-Murillas, Isaac, Cristofanilli, Massimo, Huang Bartlett, Cynthia, Turner, Nicholas C.
Published in Cancer discovery (01.11.2018)
Published in Cancer discovery (01.11.2018)
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Journal Article
Early circulating tumor DNA dynamics and clonal selection with palbociclib and fulvestrant for breast cancer
O’Leary, Ben, Hrebien, Sarah, Morden, James P., Beaney, Matthew, Fribbens, Charlotte, Huang, Xin, Liu, Yuan, Bartlett, Cynthia Huang, Koehler, Maria, Cristofanilli, Massimo, Garcia-Murillas, Isaac, Bliss, Judith M., Turner, Nicholas C.
Published in Nature communications (01.03.2018)
Published in Nature communications (01.03.2018)
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Journal Article
Plasma ESR1 Mutations and the Treatment of Estrogen Receptor–Positive Advanced Breast Cancer
Fribbens, Charlotte, O’Leary, Ben, Kilburn, Lucy, Hrebien, Sarah, Garcia-Murillas, Isaac, Beaney, Matthew, Cristofanilli, Massimo, Andre, Fabrice, Loi, Sherene, Loibl, Sibylle, Jiang, John, Bartlett, Cynthia Huang, Koehler, Maria, Dowsett, Mitch, Bliss, Judith M., Johnston, Stephen R.D., Turner, Nicholas C.
Published in Journal of clinical oncology (01.09.2016)
Published in Journal of clinical oncology (01.09.2016)
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Journal Article
Genomic profile of advanced breast cancer in circulating tumour DNA
Kingston, Belinda, Cutts, Rosalind J., Bye, Hannah, Beaney, Matthew, Walsh-Crestani, Giselle, Hrebien, Sarah, Swift, Claire, Kilburn, Lucy S., Kernaghan, Sarah, Moretti, Laura, Wilkinson, Katie, Wardley, Andrew M., Macpherson, Iain R., Baird, Richard D., Roylance, Rebecca, Reis-Filho, Jorge S., Hubank, Michael, Faull, Iris, Banks, Kimberly C., Lanman, Richard B., Garcia-Murillas, Isaac, Bliss, Judith M., Ring, Alistair, Turner, Nicholas C.
Published in Nature communications (23.04.2021)
Published in Nature communications (23.04.2021)
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Journal Article
The Spatiotemporal Evolution of Lymph Node Spread in Early Breast Cancer
Barry, Peter, Vatsiou, Alexandra, Spiteri, Inmaculada, Nichol, Daniel, Cresswell, George D., Acar, Ahmet, Trahearn, Nicholas, Hrebien, Sarah, Garcia-Murillas, Isaac, Chkhaidze, Kate, Ermini, Luca, Huntingford, Ian Said, Cottom, Hannah, Zabaglo, Lila, Koelble, Konrad, Khalique, Saira, Rusby, Jennifer E., Muscara, Francesca, Dowsett, Mitch, Maley, Carlo C., Natrajan, Rachael, Yuan, Yinyin, Schiavon, Gaia, Turner, Nicholas, Sottoriva, Andrea
Published in Clinical cancer research (01.10.2018)
Published in Clinical cancer research (01.10.2018)
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Journal Article
Reproducibility of Digital PCR Assays for Circulating Tumor DNA Analysis in Advanced Breast Cancer
Hrebien, Sarah, O’Leary, Ben, Beaney, Matthew, Schiavon, Gaia, Fribbens, Charlotte, Bhambra, Amarjit, Johnson, Richard, Garcia-Murillas, Isaac, Turner, Nicholas
Published in PloS one (19.10.2016)
Published in PloS one (19.10.2016)
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Journal Article
Author Correction: Genomic profile of advanced breast cancer in circulating tumor DNA
Kingston, Belinda, Cutts, Rosalind J., Bye, Hannah, Beaney, Matthew, Walsh-Crestani, Giselle, Hrebien, Sarah, Swift, Claire, Kilburn, Lucy S., Kernaghan, Sarah, Moretti, Laura, Wilkinson, Katie, Wardley, Andrew M., Macpherson, Iain R., Baird, Richard D., Roylance, Rebecca, Reis-Filho, Jorge S., Hubank, Michael, Faull, Iris, Banks, Kimberly C., Lanman, Richard B., Garcia-Murillas, Isaac, Bliss, Judith M., Ring, Alistair, Turner, Nicholas C.
Published in Nature communications (16.07.2021)
Published in Nature communications (16.07.2021)
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Journal Article
Circulating Tumor DNA Markers for Early Progression on Fulvestrant With or Without Palbociclib in ER+ Advanced Breast Cancer
O’Leary, Ben, Cutts, Rosalind J, Huang, Xin, Hrebien, Sarah, Liu, Yuan, André, Fabrice, Loibl, Sibylle, Loi, Sherene, Garcia-Murillas, Isaac, Cristofanilli, Massimo, Bartlett, Cynthia Huang, Turner, Nicholas C
Published in JNCI : Journal of the National Cancer Institute (01.03.2021)
Published in JNCI : Journal of the National Cancer Institute (01.03.2021)
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Journal Article
Comparison of BEAMing and Droplet Digital PCR for Circulating Tumor DNA Analysis
O'Leary, Ben, Hrebien, Sarah, Beaney, Matthew, Fribbens, Charlotte, Garcia-Murillas, Isaac, Jiang, John, Li, Yuan, Huang Bartlett, Cynthia, André, Fabrice, Loibl, Sibylle, Loi, Sherene, Cristofanilli, Massimo, Turner, Nicholas C
Published in Clinical chemistry (Baltimore, Md.) (01.11.2019)
Published in Clinical chemistry (Baltimore, Md.) (01.11.2019)
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Journal Article
Tracking evolution of aromatase inhibitor resistance with circulating tumour DNA analysis in metastatic breast cancer
Fribbens, C., Garcia Murillas, I., Beaney, M., Hrebien, S., O’Leary, B., Kilburn, L., Howarth, K., Epstein, M., Green, E., Rosenfeld, N., Ring, A., Johnston, S., Turner, N.
Published in Annals of oncology (01.01.2018)
Published in Annals of oncology (01.01.2018)
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Journal Article
Longitudinal monitoring of circulating tumor DNA to detect relapse early and predict outcome in early breast cancer
Garcia-Murillas, Isaac, Cutts, Rosalind J., Walsh-Crestani, Giselle, Phillips, Edward, Hrebien, Sarah, Dunne, Kathryn, Sidhu, Kally, Daber, Robert, Hubert, Benjamin, Graybill, Chiharu, DeFord, Peter M., Wooten, David J., Zhao, Jianhua, Ellsworth, Rachel E., Johnston, Stephen R. D., Ring, Alistair, Russell, Simon, Evans, Abigail, Skene, Anthony, Wheatley, Duncan, Smith, Ian E., Korn, W. Michael, Turner, Nicholas C.
Published in Breast cancer research and treatment (01.02.2025)
Published in Breast cancer research and treatment (01.02.2025)
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Journal Article
Discriminating subtypes in advanced breast cancer with ctDNA methylation profiling
Pasha, Nida, Amenssag, Aya, Hrebien, Sarah, Gulati, Aditi, Gao, Qiong, Haider, Syed, Roylance, Rebecca, Tutt, Andrew N. J., Baird, Richard D., MacPherson, Iain R., Ring, Alistair E., Johnston, Stephen R. D., Okines, Alicia Frances Clare, Garcia-Murillas, Isaac, Filippi, Sarah, Turner, Nicholas C.
Published in Journal of clinical oncology (01.06.2024)
Published in Journal of clinical oncology (01.06.2024)
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Journal Article
Triplet Therapy with Palbociclib, Taselisib, and Fulvestrant in PIK3CA -Mutant Breast Cancer and Doublet Palbociclib and Taselisib in Pathway-Mutant Solid Cancers
Pascual, Javier, Lim, Joline S.J., Macpherson, Iain R., Armstrong, Anne C., Ring, Alistair, Okines, Alicia F.C., Cutts, Rosalind J., Herrera-Abreu, Maria Teresa, Garcia-Murillas, Isaac, Pearson, Alex, Hrebien, Sarah, Gevensleben, Heidrun, Proszek, Paula Z., Hubank, Michael, Hills, Margaret, King, Jenny, Parmar, Mona, Prout, Toby, Finneran, Laura, Malia, Jason, Swales, Karen E., Ruddle, Ruth, Raynaud, Florence I., Turner, Alison, Hall, Emma, Yap, Timothy A., Lopez, Juanita S., Turner, Nicholas C.
Published in Cancer discovery (01.01.2021)
Published in Cancer discovery (01.01.2021)
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Journal Article
Abstract P2-01-10: Detection of ctDNA following surgery predicts relapse in breast cancer patients receiving primary surgery
Garcia-Murillas, Isaac, Cutts, Rosalind J, Ulrich, Lara, Beaney, Matthew, Robert, Marie, Coakley, Maria, Bunce, Catey, WalshCrestani, Giselle, Hrebien, Sarah, Kalashnikova, Ekaterina, Wu, Hsin-Ta, Dashner, Scott, Sethi, Himanshu, Aleshin, Alexey, Ring, Alistair, Okines, Alicia, Smith, Ian E, Dowsett, Mitch, Barry, Peter, Turner, Nicholas C
Published in Cancer research (Chicago, Ill.) (15.02.2022)
Published in Cancer research (Chicago, Ill.) (15.02.2022)
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Journal Article
Genomic markers of early progression on fulvestrant with or without palbociclib for ER+ advanced breast cancer in the PALOMA-3 trial
O'Leary, Ben, Cutts, Ros, Huang, Xin, Hrebien, Sarah, Liu, Yuan, Garcia-Murillas, Isaac, Andre, Fabrice, Loi, Sherene, Loibl, Sibylle, Cristofanilli, Massimo, Bartlett, Cynthia Huang, Turner, Nicholas C.
Published in Journal of clinical oncology (20.05.2019)
Published in Journal of clinical oncology (20.05.2019)
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Journal Article
Abstract 2743: Comparison of enhanced Tagged-Amplicon Sequencing and digital PCR for circulating tumor DNA analysis in advanced breast cancer
Garcia-Murillas, Isaac, Beanney, Matthew, Epstein, Michael, Howarth, Karen, Lawson, Andrew, Hrebien, Sarah, Green, Emma, Rosenfeld, Nitzan, Turner, Nick
Published in Cancer research (Chicago, Ill.) (01.07.2017)
Published in Cancer research (Chicago, Ill.) (01.07.2017)
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Journal Article
Abstract PS5-02: Assessment of early ctDNA dynamics to predict efficacy of targeted therapies in metastatic breast cancer: Results from plasmaMATCH trial
Pascual, Javier, Cutts, Rosalind J, Kingston, Belinda, Hrebien, Sarah, Kilburn, Lucy S, Kernaghan, Sarah, Moretti, Laura, Wilkinson, Katie, Wardley, Andrew M, Macpherson, Iain R, Baird, Richard D, Roylance, Rebecca, Hubank, Michael, Walsh, Giselle, Faull, Iris, Banks, Kimberly C, Lanman, Richard B, Garcia-Murillas, Isaac, Bliss, Judith M, Ring, Alistair, Turner, Nicholas C
Published in Cancer research (Chicago, Ill.) (15.02.2021)
Published in Cancer research (Chicago, Ill.) (15.02.2021)
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Journal Article
Tracking evolution of aromatase inhibitor resistance with circulating tumour DNA (ctDNA) in metastatic breast cancer
Fribbens, Charlotte Victoria, Garcia-Murillas, Isaac, Beaney, Matthew, Hrebien, Sarah, Howarth, Karen, Epstein, Michael, Rosenfeld, Nitzan, Ring, Alistair E., Johnston, Stephen R. D., Turner, Nicholas C.
Published in Journal of clinical oncology (20.05.2017)
Published in Journal of clinical oncology (20.05.2017)
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Journal Article
Predicting sensitivity to palbociclib with early circulating tumor DNA dynamics in the PALOMA-3 trial
O'Leary, Ben, Hrebien, Sarah, Morden, James P, Beaney, Matthew, Liu, Yuan, Bartlett, Cynthia Huang, Koehler, Maria, Cristofanilli, Massimo, Garcia-Murillas, Isaac, Bliss, Judith, Turner, Nicholas C.
Published in Journal of clinical oncology (20.05.2017)
Published in Journal of clinical oncology (20.05.2017)
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Journal Article
Genetic landscape of resistance to CDK4/6 inhibition in circulating tumor DNA (ctDNA) analysis of the PALOMA3 trial of palbociclib and fulvestrant versus placebo and fulvestrant
Turner, Nicholas C., O'Leary, Ben, Cutts, Ros, Liu, Yuan, Hrebien, Sarah, Huang, Xin, Beaney, Matthew, Fenwick, Kerry, Andre, Fabrice, Loibl, Sibylle, Loi, Sherene, Garcia-Murillas, Isaac, Bartlett, Cynthia Huang, Cristofanilli, Massimo
Published in Journal of clinical oncology (20.05.2018)
Published in Journal of clinical oncology (20.05.2018)
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Journal Article