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Mechanisms linking circadian clocks, sleep, and neurodegeneration
Musiek, Erik S., Holtzman, David M.
Published in Science (American Association for the Advancement of Science) (25.11.2016)
Published in Science (American Association for the Advancement of Science) (25.11.2016)
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Journal Article
ApoE Cascade Hypothesis in the pathogenesis of Alzheimer’s disease and related dementias
Martens, Yuka A., Zhao, Na, Liu, Chia-Chen, Kanekiyo, Takahisa, Yang, Austin J., Goate, Alison M., Holtzman, David M., Bu, Guojun
Published in Neuron (Cambridge, Mass.) (20.04.2022)
Published in Neuron (Cambridge, Mass.) (20.04.2022)
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Journal Article
Elucidating the Role of TREM2 in Alzheimer’s Disease
Ulrich, Jason D., Ulland, Tyler K., Colonna, Marco, Holtzman, David M.
Published in Neuron (Cambridge, Mass.) (19.04.2017)
Published in Neuron (Cambridge, Mass.) (19.04.2017)
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Journal Article
Microglia drive APOE-dependent neurodegeneration in a tauopathy mouse model
Shi, Yang, Manis, Melissa, Long, Justin, Wang, Kairuo, Sullivan, Patrick M., Remolina Serrano, Javier, Hoyle, Rosa, Holtzman, David M.
Published in The Journal of experimental medicine (04.11.2019)
Published in The Journal of experimental medicine (04.11.2019)
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Journal Article
New insights into the role of TREM2 in Alzheimer’s disease
Gratuze, Maud, Leyns, Cheryl E. G., Holtzman, David M.
Published in Molecular neurodegeneration (20.12.2018)
Published in Molecular neurodegeneration (20.12.2018)
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Journal Article
Sleep, circadian rhythms, and the pathogenesis of Alzheimer Disease
Musiek, Erik S, Xiong, David D, Holtzman, David M
Published in Experimental & molecular medicine (13.03.2015)
Published in Experimental & molecular medicine (13.03.2015)
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Journal Article
Changes in insulin and insulin signaling in Alzheimer’s disease: cause or consequence?
Stanley, Molly, Macauley, Shannon L., Holtzman, David M.
Published in The Journal of experimental medicine (25.07.2016)
Published in The Journal of experimental medicine (25.07.2016)
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Journal Article
Selective removal of astrocytic APOE4 strongly protects against tau-mediated neurodegeneration and decreases synaptic phagocytosis by microglia
Wang, Chao, Xiong, Monica, Gratuze, Maud, Bao, Xin, Shi, Yang, Andhey, Prabhakar Sairam, Manis, Melissa, Schroeder, Caitlin, Yin, Zhuoran, Madore, Charlotte, Butovsky, Oleg, Artyomov, Maxim, Ulrich, Jason D., Holtzman, David M.
Published in Neuron (Cambridge, Mass.) (19.05.2021)
Published in Neuron (Cambridge, Mass.) (19.05.2021)
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Journal Article
Anti-Tau Antibodies that Block Tau Aggregate Seeding In Vitro Markedly Decrease Pathology and Improve Cognition In Vivo
Yanamandra, Kiran, Kfoury, Najla, Jiang, Hong, Mahan, Thomas E., Ma, Shengmei, Maloney, Susan E., Wozniak, David F., Diamond, Marc I., Holtzman, David M.
Published in Neuron (Cambridge, Mass.) (16.10.2013)
Published in Neuron (Cambridge, Mass.) (16.10.2013)
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Journal Article
The Role of Apolipoprotein E in Alzheimer's Disease
Kim, Jungsu, Basak, Jacob M., Holtzman, David M.
Published in Neuron (Cambridge, Mass.) (13.08.2009)
Published in Neuron (Cambridge, Mass.) (13.08.2009)
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Journal Article
The sleep-wake cycle regulates brain interstitial fluid tau in mice and CSF tau in humans
Holth, Jerrah K., Fritschi, Sarah K., Wang, Chanung, Pedersen, Nigel P., Cirrito, John R., Mahan, Thomas E., Finn, Mary Beth, Manis, Melissa, Geerling, Joel C., Fuller, Patrick M., Lucey, Brendan P., Holtzman, David M.
Published in Science (American Association for the Advancement of Science) (22.02.2019)
Published in Science (American Association for the Advancement of Science) (22.02.2019)
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Journal Article
Dietary salt promotes cognitive impairment through tau phosphorylation
Faraco, Giuseppe, Hochrainer, Karin, Segarra, Steven G., Schaeffer, Samantha, Santisteban, Monica M., Menon, Ajay, Jiang, Hong, Holtzman, David M., Anrather, Josef, Iadecola, Costantino
Published in Nature (London) (31.10.2019)
Published in Nature (London) (31.10.2019)
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Journal Article