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Overall Survival Results From the POLO Trial: A Phase III Study of Active Maintenance Olaparib Versus Placebo for Germline BRCA-Mutated Metastatic Pancreatic Cancer
Kindler, Hedy L., Hammel, Pascal, Reni, Michele, Van Cutsem, Eric, Macarulla, Teresa, Hall, Michael J., Park, Joon Oh, Hochhauser, Daniel, Arnold, Dirk, Oh, Do-Youn, Reinacher-Schick, Anke, Tortora, Giampaolo, Algül, Hana, O'Reilly, Eileen M., Bordia, Sonal, McGuinness, David, Cui, Karen, Locker, Gershon Y., Golan, Talia
Published in Journal of clinical oncology (01.12.2022)
Published in Journal of clinical oncology (01.12.2022)
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Journal Article
Tracking the Genomic Evolution of Esophageal Adenocarcinoma through Neoadjuvant Chemotherapy
Murugaesu, Nirupa, Wilson, Gareth A., Birkbak, Nicolai J., Watkins, Thomas B.K., McGranahan, Nicholas, Kumar, Sacheen, Abbassi-Ghadi, Nima, Salm, Max, Mitter, Richard, Horswell, Stuart, Rowan, Andrew, Phillimore, Benjamin, Biggs, Jennifer, Begum, Sharmin, Matthews, Nik, Hochhauser, Daniel, Hanna, George B., Swanton, Charles
Published in Cancer discovery (01.08.2015)
Published in Cancer discovery (01.08.2015)
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Journal Article
Multiple criteria decision analysis in the context of health technology assessment: a simulation exercise on metastatic colorectal cancer with multiple stakeholders in the English setting
Angelis, Aris, Montibeller, Gilberto, Hochhauser, Daniel, Kanavos, Panos
Published in BMC medical informatics and decision making (26.10.2017)
Published in BMC medical informatics and decision making (26.10.2017)
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Journal Article
The MEK1/2 Inhibitor Pimasertib Enhances Gemcitabine Efficacy in Pancreatic Cancer Models by Altering Ribonucleotide Reductase Subunit-1 (RRM1)
Vena, Francesca, Li Causi, Eleonora, Rodriguez-Justo, Manuel, Goodstal, Samantha, Hagemann, Thorsten, Hartley, John A., Hochhauser, Daniel
Published in Clinical cancer research (15.12.2015)
Published in Clinical cancer research (15.12.2015)
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Journal Article
Role of Reactive Oxygen Species in the Abrogation of Oxaliplatin Activity by Cetuximab in Colorectal Cancer
Santoro, Valeria, Jia, Ruochen, Thompson, Hannah, Nijhuis, Anke, Jeffery, Rosemary, Kiakos, Konstantinos, Silver, Andrew R., Hartley, John A., Hochhauser, Daniel
Published in JNCI : Journal of the National Cancer Institute (01.06.2016)
Published in JNCI : Journal of the National Cancer Institute (01.06.2016)
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Journal Article
WASH and Tsg101/ALIX-dependent diversion of stress-internalized EGFR from the canonical endocytic pathway
Tomas, Alejandra, Vaughan, Simon O., Burgoyne, Thomas, Sorkin, Alexander, Hartley, John A., Hochhauser, Daniel, Futter, Clare E.
Published in Nature communications (12.06.2015)
Published in Nature communications (12.06.2015)
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Journal Article
Targeting of EGFR by a combination of antibodies mediates unconventional EGFR trafficking and degradation
Jones, Sylwia, King, Peter J., Antonescu, Costin N., Sugiyama, Michael G., Bhamra, Amandeep, Surinova, Silvia, Angelopoulos, Nicos, Kragh, Michael, Pedersen, Mikkel W., Hartley, John A., Futter, Clare E., Hochhauser, Daniel
Published in Scientific reports (20.01.2020)
Published in Scientific reports (20.01.2020)
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Journal Article
Liver resection surgery compared with thermal ablation in high surgical risk patients with colorectal liver metastases: the LAVA international RCT
Davidson, Brian, Gurusamy, Kurinchi, Corrigan, Neil, Croft, Julie, Ruddock, Sharon, Pullan, Alison, Brown, Julia, Twiddy, Maureen, Birtwistle, Jaqueline, Morris, Stephen, Woodward, Nick, Bandula, Steve, Hochhauser, Daniel, Prasad, Raj, Olde Damink, Steven, Coolson, Marielle, Laarhoven, K van, de Wilt, Johannes HW
Published in Health technology assessment (Winchester, England) (01.04.2020)
Published in Health technology assessment (Winchester, England) (01.04.2020)
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Journal Article
Liver resection surgery versus thermal ablation for colorectal LiVer MetAstases (LAVA): study protocol for a randomised controlled trial
Gurusamy, Kurinchi, Corrigan, Neil, Croft, Julie, Twiddy, Maureen, Morris, Stephen, Woodward, Nick, Bandula, Steve, Hochhauser, Daniel, Napp, Vicky, Pullan, Alison, Jakowiw, Nicholas, Prasad, Raj, Damink, Steven Olde, van Laarhoven, C. J. H. M., de Wilt, Johannes H. W., Brown, Julia, Davidson, Brian R.
Published in Current controlled trials in cardiovascular medicine (13.02.2018)
Published in Current controlled trials in cardiovascular medicine (13.02.2018)
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Journal Article
Molecular effects of Lapatinib in the treatment of HER2 overexpressing oesophago-gastric adenocarcinoma
De Silva, Nadeera, Schulz, Laura, Paterson, Anna, Qain, Wendi, Secrier, Maria, Godfrey, Edmund, Cheow, Heok, O'Donovan, Maria, Lao-Sirieix, Pierre, Jobanputra, Minesh, Hochhauser, Daniel, Fitzgerald, Rebecca, Ford, Hugo
Published in British journal of cancer (03.11.2015)
Published in British journal of cancer (03.11.2015)
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Journal Article
Efficacy of pembrolizumab (pembro) monotherapy versus chemotherapy for PD-L1–positive (CPS ≥10) advanced G/GEJ cancer in the phase II KEYNOTE-059 (cohort 1) and phase III KEYNOTE-061 and KEYNOTE-062 studies
Wainberg, Zev A., Fuchs, Charles S., Tabernero, Josep, Shitara, Kohei, Muro, Kei, Van Cutsem, Eric, Bang, Yung-Jue, Chung, Hyun Cheol, Yamaguchi, Kensei, Varga, Eniko, Chen, Jen-Shi, Hochhauser, Daniel, Thuss-Patience, Peter C., Al-Batran, Salah-Eddin, Garrido, Marcelo, Kher, Uma, Shih, Chie-Schin, Shah, Sukrut, Bhagia, Pooja, Chao, Joseph
Published in Journal of clinical oncology (01.02.2020)
Published in Journal of clinical oncology (01.02.2020)
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Journal Article
Outcomes of the 2019 novel coronavirus in patients with or without a history of cancer: a multi-centre North London experience
Joharatnam-Hogan, Nalinie, Hochhauser, Daniel, Shiu, Kai-Keen, Rush, Hannah, Crolley, Valerie, Wilson, William, Sharma, Anand, Muhammad, Aun, Anwar, Muhammad, Vasdev, Nikhil, Goldstein, Robert, Kantser, Ganna, Saha, Aramita, Raja, Fharat, Bridgewater, John, Khan, Khurum
Published in Therapeutic advances in medical oncology (2020)
Published in Therapeutic advances in medical oncology (2020)
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Journal Article
Pembrolizumab in previously treated metastatic esophageal cancer: Longer term follow-up from the phase 2 KEYNOTE-180 Study
Kato, Ken, Kojima, Takashi, Hochhauser, Daniel, Bennouna, Jaafar, Hollebecque, Antoine, Lordick, Florian, Kim, Sung-Bae, Tajika, Masahiro, Kim, Heung Tae, Park, Haeseong, Saba, Nabil F., Urba, Susan, Desai, Anjali, Liu, Qi, Cruz, Sandra, Shah, Manish A.
Published in Journal of Clinical Oncology (20.05.2019)
Published in Journal of Clinical Oncology (20.05.2019)
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Journal Article
Effect of Remote Ischaemic Conditioning in Oncology Patients Undergoing Chemotherapy: Rationale and Design of the ERIC‐ONC Study—A Single‐Center, Blinded, Randomized Controlled Trial
Chung, Robin, Maulik, Angshuman, Hamarneh, Ashraf, Hochhauser, Daniel, Hausenloy, Derek J., Walker, J. Malcolm, Yellon, Derek M.
Published in Clinical cardiology (Mahwah, N.J.) (01.02.2016)
Published in Clinical cardiology (Mahwah, N.J.) (01.02.2016)
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Journal Article
Phase I Study of Sequence-Selective Minor Groove DNA Binding Agent SJG-136 in Patients with Advanced Solid Tumors
Hochhauser, Daniel, Meyer, Timothy, Spanswick, Victoria J., Wu, Jenny, Clingen, Peter H., Loadman, Paul, Cobb, Margaret, Gumbrell, Lindsey, Begent, Richard H., Hartley, John A., Jodrell, Duncan
Published in Clinical cancer research (15.03.2009)
Published in Clinical cancer research (15.03.2009)
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Journal Article
COVID-19 in cancer patients on systemic anti-cancer therapies: outcomes from the CAPITOL (COVID-19 Cancer PatIenT Outcomes in North London) cohort study
Crolley, Valerie E., Hanna, Daire, Joharatnam-Hogan, Nalinie, Chopra, Neha, Bamac, Ekin, Desai, Meera, Lam, Yuk-Chun, Dipro, Sabiq, Kanani, Ruhi, Benson, Jack, Wilson, William, Fox, Thomas A., Shiu, Kai-Keen, Forster, Martin, Bridgewater, John, Hochhauser, Daniel, Khan, Khurum
Published in Therapeutic advances in medical oncology (2020)
Published in Therapeutic advances in medical oncology (2020)
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Journal Article
Evidence for different mechanisms of 'unhooking' for melphalan and cisplatin-induced DNA interstrand cross-links in vitro and in clinical acquired resistant tumour samples
Spanswick, Victoria J, Lowe, Helen L, Newton, Claire, Bingham, John P, Bagnobianchi, Alessia, Kiakos, Konstantinos, Craddock, Charles, Ledermann, Jonathan A, Hochhauser, Daniel, Hartley, John A
Published in BMC cancer (28.09.2012)
Published in BMC cancer (28.09.2012)
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Journal Article