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Bayesian Test for Colocalisation between Pairs of Genetic Association Studies Using Summary Statistics
Giambartolomei, Claudia, Vukcevic, Damjan, Schadt, Eric E., Franke, Lude, Hingorani, Aroon D., Wallace, Chris, Plagnol, Vincent
Published in PLoS genetics (01.05.2014)
Published in PLoS genetics (01.05.2014)
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Journal Article
Therapeutic Targets for Heart Failure Identified Using Proteomics and Mendelian Randomization
Henry, Albert, Gordillo-Marañón, María, Finan, Chris, Schmidt, Amand F., Ferreira, João Pedro, Karra, Ravi, Sundström, Johan, Lind, Lars, Ärnlöv, Johan, Zannad, Faiez, Mälarstig, Anders, Hingorani, Aroon D., Lumbers, R. Thomas
Published in Circulation (New York, N.Y.) (19.04.2022)
Published in Circulation (New York, N.Y.) (19.04.2022)
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Journal Article
Periodontitis is associated with hypertension: a systematic review and meta-analysis
Muñoz Aguilera, Eva, Suvan, Jean, Buti, Jacopo, Czesnikiewicz-Guzik, Marta, Barbosa Ribeiro, Aline, Orlandi, Marco, Guzik, Tomasz J, Hingorani, Aroon D, Nart, Jose, D’Aiuto, Francesco
Published in Cardiovascular research (01.01.2020)
Published in Cardiovascular research (01.01.2020)
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Journal Article
Mapping the proteo-genomic convergence of human diseases
Pietzner, Maik, Wheeler, Eleanor, Carrasco-Zanini, Julia, Cortes, Adrian, Koprulu, Mine, Wörheide, Maria A., Oerton, Erin, Cook, James, Stewart, Isobel D., Kerrison, Nicola D., Luan, Jian’an, Raffler, Johannes, Arnold, Matthias, Arlt, Wiebke, O’Rahilly, Stephen, Kastenmüller, Gabi, Gamazon, Eric R., Hingorani, Aroon D., Scott, Robert A., Wareham, Nicholas J., Langenberg, Claudia
Published in Science (American Association for the Advancement of Science) (12.11.2021)
Published in Science (American Association for the Advancement of Science) (12.11.2021)
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Journal Article
Blood pressure and incidence of twelve cardiovascular diseases: lifetime risks, healthy life-years lost, and age-specific associations in 1·25 million people
Rapsomaniki, Eleni, Timmis, Adam, George, Julie, Pujades-Rodriguez, Mar, Shah, Anoop D, Denaxas, Spiros, White, Ian R, Caulfield, Mark J, Deanfield, John E, Smeeth, Liam, Williams, Bryan, Hingorani, Aroon, Hemingway, Harry
Published in The Lancet (British edition) (31.05.2014)
Published in The Lancet (British edition) (31.05.2014)
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Journal Article
Genetic drug target validation using Mendelian randomisation
Schmidt, Amand F., Finan, Chris, Gordillo-Marañón, Maria, Asselbergs, Folkert W., Freitag, Daniel F., Patel, Riyaz S., Tyl, Benoît, Chopade, Sandesh, Faraway, Rupert, Zwierzyna, Magdalena, Hingorani, Aroon D.
Published in Nature communications (26.06.2020)
Published in Nature communications (26.06.2020)
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Journal Article
Role of circulating polyunsaturated fatty acids on cardiovascular diseases risk: analysis using Mendelian randomization and fatty acid genetic association data from over 114,000 UK Biobank participants
Borges, Maria Carolina, Haycock, Philip C., Zheng, Jie, Hemani, Gibran, Holmes, Michael V., Davey Smith, George, Hingorani, Aroon D., Lawlor, Deborah A.
Published in BMC medicine (13.06.2022)
Published in BMC medicine (13.06.2022)
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Journal Article
Plasma protein patterns as comprehensive indicators of health
Williams, Stephen A., Kivimaki, Mika, Langenberg, Claudia, Hingorani, Aroon D., Casas, J. P., Bouchard, Claude, Jonasson, Christian, Sarzynski, Mark A., Shipley, Martin J., Alexander, Leigh, Ash, Jessica, Bauer, Tim, Chadwick, Jessica, Datta, Gargi, DeLisle, Robert Kirk, Hagar, Yolanda, Hinterberg, Michael, Ostroff, Rachel, Weiss, Sophie, Ganz, Peter, Wareham, Nicholas J.
Published in Nature medicine (01.12.2019)
Published in Nature medicine (01.12.2019)
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Journal Article
Biological and functional multimorbidity—from mechanisms to management
Langenberg, Claudia, Hingorani, Aroon D., Whitty, Christopher J. M.
Published in Nature medicine (01.07.2023)
Published in Nature medicine (01.07.2023)
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Journal Article
Synergistic insights into human health from aptamer- and antibody-based proteomic profiling
Pietzner, Maik, Wheeler, Eleanor, Carrasco-Zanini, Julia, Kerrison, Nicola D., Oerton, Erin, Koprulu, Mine, Luan, Jian’an, Hingorani, Aroon D., Williams, Steve A., Wareham, Nicholas J., Langenberg, Claudia
Published in Nature communications (24.11.2021)
Published in Nature communications (24.11.2021)
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Journal Article
Realistic expectations are key to realising the benefits of polygenic scores
Sud, Amit, Horton, Rachel H, Hingorani, Aroon D, Tzoulaki, Ioanna, Turnbull, Clare, Houlston, Richard S, Lucassen, Anneke
Published in BMJ (Online) (28.02.2023)
Published in BMJ (Online) (28.02.2023)
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Journal Article
Biological mechanisms of aging predict age‐related disease co‐occurrence in patients
Fraser, Helen C., Kuan, Valerie, Johnen, Ronja, Zwierzyna, Magdalena, Hingorani, Aroon D., Beyer, Andreas, Partridge, Linda
Published in Aging cell (01.04.2022)
Published in Aging cell (01.04.2022)
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Journal Article
Oral anticoagulants for prevention of stroke in atrial fibrillation: systematic review, network meta-analysis, and cost effectiveness analysis
López-López, José A, Sterne, Jonathan A C, Thom, Howard H Z, Higgins, Julian P T, Hingorani, Aroon D, Okoli, George N, Davies, Philippa A, Bodalia, Pritesh N, Bryden, Peter A, Welton, Nicky J, Hollingworth, William, Caldwell, Deborah M, Savović, Jelena, Dias, Sofia, Salisbury, Chris, Eaton, Diane, Stephens-Boal, Annya, Sofat, Reecha
Published in BMJ (Online) (28.11.2017)
Published in BMJ (Online) (28.11.2017)
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Journal Article
Utility of polygenic risk scores in UK cancer screening: a modelling analysis
Huntley, Catherine, Torr, Bethany, Sud, Amit, Rowlands, Charlie F, Way, Rosalind, Snape, Katie, Hanson, Helen, Swanton, Charles, Broggio, John, Lucassen, Anneke, McCartney, Margaret, Houlston, Richard S, Hingorani, Aroon D, Jones, Michael E, Turnbull, Clare
Published in The lancet oncology (01.06.2023)
Published in The lancet oncology (01.06.2023)
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Journal Article
Pre-eclampsia and risk of cardiovascular disease and cancer in later life: systematic review and meta-analysis
Bellamy, Leanne, Casas, Juan-Pablo, Hingorani, Aroon D, Williams, David J
Published in BMJ (10.11.2007)
Published in BMJ (10.11.2007)
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Journal Article
CYP2C19 Genotype, Clopidogrel Metabolism, Platelet Function, and Cardiovascular Events: A Systematic Review and Meta-analysis
Holmes, Michael V, Perel, Pablo, Shah, Tina, Hingorani, Aroon D, Casas, Juan P
Published in JAMA : the journal of the American Medical Association (28.12.2011)
Published in JAMA : the journal of the American Medical Association (28.12.2011)
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Journal Article
Selecting instruments for Mendelian randomization in the wake of genome-wide association studies
Swerdlow, Daniel I, Kuchenbaecker, Karoline B, Shah, Sonia, Sofat, Reecha, Holmes, Michael V, White, Jon, Mindell, Jennifer S, Kivimaki, Mika, Brunner, Eric J, Whittaker, John C, Casas, Juan P, Hingorani, Aroon D
Published in International journal of epidemiology (01.10.2016)
Published in International journal of epidemiology (01.10.2016)
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Journal Article
Use of low-density lipoprotein cholesterol gene score to distinguish patients with polygenic and monogenic familial hypercholesterolaemia: a case-control study
Talmud, Philippa J, Shah, Sonia, Whittall, Ros, Futema, Marta, Howard, Philip, Cooper, Jackie A, Harrison, Seamus C, Li, KaWah, Drenos, Fotios, Karpe, Frederik, Neil, H Andrew W, Descamps, Olivier S, Langenberg, Claudia, Lench, Nicholas, Kivimaki, Mika, Whittaker, John, Hingorani, Aroon D, Kumari, Meena, Humphries, Steve E
Published in The Lancet (British edition) (13.04.2013)
Published in The Lancet (British edition) (13.04.2013)
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Journal Article