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Phenotypic and molecular characterization of the claudin-low intrinsic subtype of breast cancer
Prat, Aleix, Parker, Joel S, Karginova, Olga, Fan, Cheng, Livasy, Chad, Herschkowitz, Jason I, He, Xiaping, Perou, Charles M
Published in Breast cancer research : BCR (02.09.2010)
Published in Breast cancer research : BCR (02.09.2010)
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Journal Article
Core epithelial-to-mesenchymal transition interactome gene-expression signature is associated with claudin-low and metaplastic breast cancer subtypes
Taube, Joseph H., Herschkowitz, Jason I., Komurov, Kakajan, Zhou, Alicia Y., Gupta, Supriya, Yang, Jing, Hartwell, Kimberly, Onder, Tamer T., Gupta, Piyush B., Evans, Kurt W., Hollier, Brett G., Ram, Prahlad T., Lander, Eric S., Rosen, Jeffrey M., Weinberg, Robert A., Mani, Sendurai A.
Published in Proceedings of the National Academy of Sciences - PNAS (31.08.2010)
Published in Proceedings of the National Academy of Sciences - PNAS (31.08.2010)
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Journal Article
Residual breast cancers after conventional therapy display mesenchymal as well as tumor-initiating features
Creighton, Chad J, Li, Xiaoxian, Landis, Melissa, Dixon, J. Michael, Neumeister, Veronique M, Sjolund, Ashley, Rimm, David L, Wong, Helen, Rodriguez, Angel, Herschkowitz, Jason I, Fan, Cheng, Zhang, Xiaomei, He, Xiaping, Pavlick, Anne, Gutierrez, M. Carolina, Renshaw, Lorna, Larionov, Alexey A, Faratian, Dana, Hilsenbeck, Susan G, Perou, Charles M, Lewis, Michael T, Rosen, Jeffrey M, Chang, Jenny C
Published in Proceedings of the National Academy of Sciences - PNAS (18.08.2009)
Published in Proceedings of the National Academy of Sciences - PNAS (18.08.2009)
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Journal Article
pINDUCER lentiviral toolkit for inducible RNA interference in vitro and in vivo
Meerbrey, Kristen L, Hu, Guang, Kessler, Jessica D, Roarty, Kevin, Li, Mamie Z, Fang, Justin E, Herschkowitz, Jason I, Burrows, Anna E, Ciccia, Alberto, Sun, Tingting, Schmitt, Earlene M, Bernardi, Ronald J, Fu, Xiaoyong, Bland, Christopher S, Cooper, Thomas A, Schiff, Rachel, Rosen, Jeffrey M, Westbrook, Thomas F, Elledge, Stephen J
Published in Proceedings of the National Academy of Sciences - PNAS (01.03.2011)
Published in Proceedings of the National Academy of Sciences - PNAS (01.03.2011)
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Journal Article
Inertial Microfluidic Cell Stretcher (iMCS): Fully Automated, High‐Throughput, and Near Real‐Time Cell Mechanotyping
Deng, Yanxiang, Davis, Steven P., Yang, Fan, Paulsen, Kevin S., Kumar, Maneesh, Sinnott DeVaux, Rebecca, Wang, Xianhui, Conklin, Douglas S., Oberai, Assad, Herschkowitz, Jason I., Chung, Aram J.
Published in Small (Weinheim an der Bergstrasse, Germany) (01.07.2017)
Published in Small (Weinheim an der Bergstrasse, Germany) (01.07.2017)
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Journal Article
Transcriptomic classification of genetically engineered mouse models of breast cancer identifies human subtype counterparts
Pfefferle, Adam D, Herschkowitz, Jason I, Usary, Jerry, Chuck Harrell, Joshua, Spike, Benjamin T, Adams, Jessica R, Torres-Arzayus, Maria I, Brown, Myles, Egan, Sean E, Wahl, Geoffrey M, Rosen, Jeffrey M, Perou, Charles M
Published in Genome biology (12.11.2013)
Published in Genome biology (12.11.2013)
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Journal Article
Cis-acting super-enhancer lncRNAs as biomarkers to early-stage breast cancer
Ropri, Ali S., DeVaux, Rebecca S., Eng, Jonah, Chittur, Sridar V., Herschkowitz, Jason I.
Published in Breast cancer research : BCR (30.10.2021)
Published in Breast cancer research : BCR (30.10.2021)
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Journal Article
FOXC2 Expression Links Epithelial–Mesenchymal Transition and Stem Cell Properties in Breast Cancer
Hollier, Brett G., Tinnirello, Agata A., Werden, Steven J., Evans, Kurt W., Taube, Joseph H., Sarkar, Tapasree Roy, Sphyris, Nathalie, Shariati, Maryam, Kumar, Sreedevi V., Battula, Venkata L., Herschkowitz, Jason I., Guerra, Rudy, Chang, Jeffrey T., Miura, Naoyuki, Rosen, Jeffrey M., Mani, Sendurai A.
Published in Cancer research (Chicago, Ill.) (15.03.2013)
Published in Cancer research (Chicago, Ill.) (15.03.2013)
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Journal Article
Comparative oncogenomics identifies breast tumors enriched in functional tumor-initiating cells
Herschkowitz, Jason I, Zhao, Wei, Zhang, Mei, Usary, Jerry, Murrow, George, Edwards, David, Knezevic, Jana, Greene, Stephanie B, Darr, David, Troester, Melissa A, Hilsenbeck, Susan G, Medina, Daniel, Perou, Charles M, Rosen, Jeffrey M
Published in Proceedings of the National Academy of Sciences - PNAS (21.02.2012)
Published in Proceedings of the National Academy of Sciences - PNAS (21.02.2012)
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Journal Article
Identification of conserved gene expression features between murine mammary carcinoma models and human breast tumors
Herschkowitz, Jason I, Simin, Karl, Weigman, Victor J, Mikaelian, Igor, Usary, Jerry, Hu, Zhiyuan, Rasmussen, Karen E, Jones, Laundette P, Assefnia, Shahin, Chandrasekharan, Subhashini, Backlund, Michael G, Yin, Yuzhi, Khramtsov, Andrey I, Bastein, Roy, Quackenbush, John, Glazer, Robert I, Brown, Powel H, Green, Jeffrey E, Kopelovich, Levy, Furth, Priscilla A, Palazzo, Juan P, Olopade, Olufunmilayo I, Bernard, Philip S, Churchill, Gary A, Van Dyke, Terry, Perou, Charles M
Published in Genome biology (10.05.2007)
Published in Genome biology (10.05.2007)
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Journal Article
Loss of function of BRCA1 promotes EMT in mammary tumors through activation of TGFβR2 signaling pathway
Bai, Feng, Wang, Chuying, Liu, Xiong, Hollern, Daniel, Liu, Shiqin, Fan, Cheng, Liu, Chang, Ren, Sijia, Herschkowitz, Jason I., Zhu, Wei-Guo, Pei, Xin-Hai
Published in Cell death & disease (02.03.2022)
Published in Cell death & disease (02.03.2022)
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Journal Article
Rb deletion in mouse mammary progenitors induces luminal-B or basal-like/EMT tumor subtypes depending on p53 status
Jiang, Zhe, Deng, Tao, Jones, Robert, Li, Huiqin, Herschkowitz, Jason I., Liu, Jeff C., Weigman, Victor J., Tsao, Ming-Sound, Lane, Timothy F., Perou, Charles M., Zacksenhaus, Eldad
Published in The Journal of clinical investigation (01.09.2010)
Published in The Journal of clinical investigation (01.09.2010)
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Journal Article
Epigenetic silencing of microRNA-203 is required for EMT and cancer stem cell properties
Taube, Joseph H., Malouf, Gabriel G., Lu, Emily, Sphyris, Nathalie, Vijay, Vidya, Ramachandran, Priyanka P., Ueno, Katumasa R., Gaur, Sanchaika, Nicoloso, Milena S., Rossi, Simona, Herschkowitz, Jason I., Rosen, Jeffrey M., Issa, Jean-Pierre J., Calin, George A., Chang, Jeffrey T., Mani, Sendurai A.
Published in Scientific reports (18.09.2013)
Published in Scientific reports (18.09.2013)
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Journal Article
RB1 and p53 at the crossroad of EMT and triple-negative breast cancer
Jiang, Zhe, Jones, Robert, Liu, Jeff C., Deng, Tao, Robinson, Tyler, Chung, Philip E.D., Wang, Sharon, Herschkowitz, Jason I., Egan, Sean E., Perou, Charles M., Zacksenhaus, Eldad
Published in Cell cycle (Georgetown, Tex.) (15.05.2011)
Published in Cell cycle (Georgetown, Tex.) (15.05.2011)
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Journal Article
Met synergizes with p53 loss to induce mammary tumors that possess features of claudin-low breast cancer
Knight, Jennifer F., Lesurf, Robert, Zhao, Hong, Pinnaduwage, Dushanthi, Davis, Ryan R., Saleh, Sadiq M. I., Zuo, Dongmei, Naujokas, Monica A., Chughtai, Naila, Herschkowitz, Jason I., Prat, Aleix, Mulligan, Anna Marie, Muller, William J., Cardiff, Robert D., Gregg, Jeff P., Andrulis, Irene L., Hallett, Michael T., Park, Morag
Published in Proceedings of the National Academy of Sciences - PNAS (02.04.2013)
Published in Proceedings of the National Academy of Sciences - PNAS (02.04.2013)
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Journal Article
Predicting Drug Responsiveness in Human Cancers Using Genetically Engineered Mice
Usary, Jerry, Zhao, Wei, Darr, David, Roberts, Patrick J., Liu, Mei, Balletta, Lorraine, Karginova, Olga, Jordan, Jamie, Combest, Austin, Bridges, Arlene, Prat, Aleix, Cheang, Maggie C. U., Herschkowitz, Jason I., Rosen, Jeffrey M., Zamboni, William, Sharpless, Norman E., Perou, Charles M.
Published in Clinical cancer research (01.09.2013)
Published in Clinical cancer research (01.09.2013)
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Journal Article
Interacting with tumor cells weakens the intrinsic clockwise chirality of endothelial cells
Hang, Benson, Jassem, Eman, Mohammed, Hanan, Wan, Leo Q., Herschkowitz, Jason I., Fan, Jie
Published in APL bioengineering (01.12.2022)
Published in APL bioengineering (01.12.2022)
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Journal Article
The ups and downs of miR-205: Identifying the roles of miR-205 in mammary gland development and breast cancer
Greene, Stephanie B., Herschkowitz, Jason I., Rosen, Jeffrey M.
Published in RNA biology (01.05.2010)
Published in RNA biology (01.05.2010)
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Journal Article
ETV6-NTRK3 Fusion Oncogene Initiates Breast Cancer from Committed Mammary Progenitors via Activation of AP1 Complex
Li, Zhe, Tognon, Cristina E., Godinho, Frank J., Yasaitis, Laura, Hock, Hanno, Herschkowitz, Jason I., Lannon, Chris L., Cho, Eunah, Kim, Seong-Jin, Bronson, Roderick T., Perou, Charles M., Sorensen, Poul H., Orkin, Stuart H.
Published in Cancer cell (01.12.2007)
Published in Cancer cell (01.12.2007)
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Journal Article
Genomic profiling of murine mammary tumors identifies potential personalized drug targets for p53 deficient mammary cancers
Pfefferle, Adam D., Agrawal, Yash N., Koboldt, Daniel C., Kanchi, Krishna L., Herschkowitz, Jason I., Mardis, Elaine R., Rosen, Jeffrey M., Perou, Charles M.
Published in Disease models & mechanisms (01.07.2016)
Published in Disease models & mechanisms (01.07.2016)
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Journal Article