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SUCNR1 controls an anti-inflammatory program in macrophages to regulate the metabolic response to obesity
Keiran, Noelia, Ceperuelo-Mallafré, Victoria, Calvo, Enrique, Hernández-Alvarez, Maria Isabel, Ejarque, Miriam, Núñez-Roa, Catalina, Horrillo, Daniel, Maymó-Masip, Elsa, Rodríguez, M. Mar, Fradera, Rosa, de la Rosa, Juan Vladimir, Jorba, Rosa, Megia, Ana, Zorzano, Antonio, Medina-Gómez, Gema, Serena, Carolina, Castrillo, Antonio, Vendrell, Joan, Fernández-Veledo, Sonia
Published in Nature immunology (01.05.2019)
Published in Nature immunology (01.05.2019)
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Journal Article
Mfn2 deficiency links age-related sarcopenia and impaired autophagy to activation of an adaptive mitophagy pathway
Sebastián, David, Sorianello, Eleonora, Segalés, Jessica, Irazoki, Andrea, Ruiz-Bonilla, Vanessa, Sala, David, Planet, Evarist, Berenguer-Llergo, Antoni, Muñoz, Juan Pablo, Sánchez-Feutrie, Manuela, Plana, Natàlia, Hernández-Álvarez, María Isabel, Serrano, Antonio L, Palacín, Manuel, Zorzano, Antonio
Published in The EMBO journal (01.08.2016)
Published in The EMBO journal (01.08.2016)
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Journal Article
Mfn2 modulates the UPR and mitochondrial function via repression of PERK
Muñoz, Juan Pablo, Ivanova, Saška, Sánchez-Wandelmer, Jana, Martínez-Cristóbal, Paula, Noguera, Eduard, Sancho, Ana, Díaz-Ramos, Angels, Hernández-Alvarez, María Isabel, Sebastián, David, Mauvezin, Caroline, Palacín, Manuel, Zorzano, Antonio
Published in The EMBO journal (28.08.2013)
Published in The EMBO journal (28.08.2013)
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Journal Article
Mitofusin 2 (Mfn2) links mitochondrial and endoplasmic reticulum function with insulin signaling and is essential for normal glucose homeostasis
Sebastián, David, Hernández-Alvarez, María Isabel, Segalés, Jessica, Sorianello, Eleonora, Muñoz, Juan Pablo, Sala, David, Waget, Aurélie, Liesa, Marc, Paz, José C, Gopalacharyulu, Peddinti, Orešič, Matej, Pich, Sara, Burcelin, Rémy, Palacín, Manuel, Zorzano, Antonio
Published in Proceedings of the National Academy of Sciences - PNAS (03.04.2012)
Published in Proceedings of the National Academy of Sciences - PNAS (03.04.2012)
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Journal Article
Regulation of death receptor signaling by the autophagy protein TP53INP2
Ivanova, Saška, Polajnar, Mira, Narbona‐Perez, Alvaro Jesus, Hernandez‐Alvarez, Maria Isabel, Frager, Petra, Slobodnyuk, Konstantin, Plana, Natalia, Nebreda, Angel R, Palacin, Manuel, Gomis, Roger R, Behrends, Christian, Zorzano, Antonio
Published in The EMBO journal (15.05.2019)
Published in The EMBO journal (15.05.2019)
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Journal Article
Critical reappraisal confirms that Mitofusin 2 is an endoplasmic reticulum–mitochondria tether
Naon, Deborah, Zaninello, Marta, Giacomello, Marta, Varanita, Tatiana, Grespi, Francesca, Lakshminaranayan, Sowmya, Serafini, Annalisa, Semenzato, Martina, Herkenne, Stephanie, Hernández-Alvarez, Maria Isabel, Zorzano, Antonio, De Stefani, Diego, Dorn, Gerald W., Scorrano, Luca
Published in Proceedings of the National Academy of Sciences - PNAS (04.10.2016)
Published in Proceedings of the National Academy of Sciences - PNAS (04.10.2016)
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Journal Article
Deficient Endoplasmic Reticulum-Mitochondrial Phosphatidylserine Transfer Causes Liver Disease
Hernández-Alvarez, María Isabel, Sebastián, David, Vives, Sara, Ivanova, Saška, Bartoccioni, Paola, Kakimoto, Pamela, Plana, Natalia, Veiga, Sónia R., Hernández, Vanessa, Vasconcelos, Nuno, Peddinti, Gopal, Adrover, Anna, Jové, Mariona, Pamplona, Reinald, Gordaliza-Alaguero, Isabel, Calvo, Enrique, Cabré, Noemí, Castro, Rui, Kuzmanic, Antonija, Boutant, Marie, Sala, David, Hyotylainen, Tuulia, Orešič, Matej, Fort, Joana, Errasti-Murugarren, Ekaitz, Rodrígues, Cecilia M.P., Orozco, Modesto, Joven, Jorge, Cantó, Carles, Palacin, Manuel, Fernández-Veledo, Sonia, Vendrell, Joan, Zorzano, Antonio
Published in Cell (02.05.2019)
Published in Cell (02.05.2019)
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Journal Article
The mitochondrial negative regulator MCJ is a therapeutic target for acetaminophen-induced liver injury
Barbier-Torres, Lucía, Iruzubieta, Paula, Fernández-Ramos, David, Delgado, Teresa C., Taibo, Daniel, Guitiérrez-de-Juan, Virginia, Varela-Rey, Marta, Azkargorta, Mikel, Navasa, Nicolas, Fernández-Tussy, Pablo, Zubiete-Franco, Imanol, Simon, Jorge, Lopitz-Otsoa, Fernando, Lachiondo-Ortega, Sofia, Crespo, Javier, Masson, Steven, McCain, Misti Vanette, Villa, Erica, Reeves, Helen, Elortza, Felix, Lucena, Maria Isabel, Hernández-Alvarez, Maria Isabel, Zorzano, Antonio, Andrade, Raúl J., Lu, Shelly C., Mato, José M., Anguita, Juan, Rincón, Mercedes, Martínez-Chantar, María Luz
Published in Nature communications (12.12.2017)
Published in Nature communications (12.12.2017)
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Journal Article
Mfn1 Deficiency in the Liver Protects Against Diet-Induced Insulin Resistance and Enhances the Hypoglycemic Effect of Metformin
Kulkarni, Sameer S., Joffraud, Magali, Boutant, Marie, Ratajczak, Joanna, Gao, Arwen W., Maclachlan, Catherine, Hernandez-Alvarez, Maria Isabel, Raymond, Frédéric, Metairon, Sylviane, Descombes, Patrick, Houtkooper, Riekelt H., Zorzano, Antonio, Cantó, Carles
Published in Diabetes (New York, N.Y.) (01.12.2016)
Published in Diabetes (New York, N.Y.) (01.12.2016)
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Journal Article
Role of the Transforming Growth Factor-β in regulating hepatocellular carcinoma oxidative metabolism
Soukupova, Jitka, Malfettone, Andrea, Hyroššová, Petra, Hernández-Alvarez, María-Isabel, Peñuelas-Haro, Irene, Bertran, Esther, Junza, Alexandra, Capellades, Jordi, Giannelli, Gianluigi, Yanes, Oscar, Zorzano, Antonio, Perales, José Carlos, Fabregat, Isabel
Published in Scientific reports (02.10.2017)
Published in Scientific reports (02.10.2017)
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Journal Article
Deregulation of Lipid Homeostasis: A Fa(c)t in the Development of Metabolic Diseases
Cisa-Wieczorek, Sabina, Hernández-Alvarez, María Isabel
Published in Cells (Basel, Switzerland) (04.12.2020)
Published in Cells (Basel, Switzerland) (04.12.2020)
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Journal Article
Phospholipid Membrane Transport and Associated Diseases
Ventura, Raúl, Martínez-Ruiz, Inma, Hernández-Alvarez, María Isabel
Published in Biomedicines (23.05.2022)
Published in Biomedicines (23.05.2022)
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Journal Article
Subjects With Early-Onset Type 2 Diabetes Show Defective Activation of the Skeletal Muscle PGC-1α/Mitofusin-2 Regulatory Pathway in Response to Physical Activity
Hernández-Alvarez, María Isabel, Thabit, Hood, Burns, Nicole, Shah, Syed, Brema, Imad, Hatunic, Mensud, Finucane, Francis, Liesa, Marc, Chiellini, Chiara, Naon, Deborah, Zorzano, Antonio, Nolan, John J
Published in Diabetes care (01.03.2010)
Published in Diabetes care (01.03.2010)
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Journal Article
Endoplasmic Reticulum Isolation: An Optimized Approach into Cells and Mouse Liver Fractionation
Leiro, Marc, Ventura, Raúl, Rojo-Querol, Nil, Hernández-Alvarez, María
Published in Bio-protocol (05.09.2023)
Published in Bio-protocol (05.09.2023)
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Journal Article
Splice variants of mitofusin 2 shape the endoplasmic reticulum and tether it to mitochondria
Naón, Déborah, Hernández-Alvarez, María Isabel, Shinjo, Satoko, Wieczor, Milosz, Ivanova, Saska, Martins de Brito, Olga, Quintana, Albert, Hidalgo, Juan, Palacín, Manuel, Aparicio, Pilar, Castellanos, Juan, Lores, Luis, Sebastián, David, Fernández-Veledo, Sonia, Vendrell, Joan, Joven, Jorge, Orozco, Modesto, Zorzano, Antonio, Scorrano, Luca
Published in Science (American Association for the Advancement of Science) (23.06.2023)
Published in Science (American Association for the Advancement of Science) (23.06.2023)
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Journal Article
Epithelial–Mesenchymal Transition (EMT) Induced by TGF-β in Hepatocellular Carcinoma Cells Reprograms Lipid Metabolism
Soukupova, Jitka, Malfettone, Andrea, Bertran, Esther, Hernández-Alvarez, María Isabel, Peñuelas-Haro, Irene, Dituri, Francesco, Giannelli, Gianluigi, Zorzano, Antonio, Fabregat, Isabel
Published in International journal of molecular sciences (24.05.2021)
Published in International journal of molecular sciences (24.05.2021)
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Journal Article
Regulation of Mitochondrial and Peroxisomal Metabolism in Female Obesity and Type 2 Diabetes
Antelo-Cea, Damián A., Martínez-Rojas, Laura, Cabrerizo-Ibáñez, Izan, Roudi Rashtabady, Ayda, Hernández-Alvarez, María Isabel
Published in International journal of molecular sciences (19.10.2024)
Published in International journal of molecular sciences (19.10.2024)
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Journal Article
SGK1 repression by WT1 may confer a survival advantage to leukemic cells under stress conditions
Rubio, Miguel A., Cisa-Wieczorek, Sabina, Mozos, Ana, Castellet, Helena, Bussaglia, Elena, Carricondo, Maite, Hernández-Alvarez, María Isabel, Sierra, Jorge, Nomdedéu, Josep F.
Published in Annals of hematology (01.07.2025)
Published in Annals of hematology (01.07.2025)
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Journal Article
Metabolic adaptations in severe obesity: Insights from circulating oxylipins before and after weight loss
Jiménez-Franco, Andrea, Castañé, Helena, Martínez-Navidad, Cristian, Placed-Gallego, Cristina, Hernández-Aguilera, Anna, Fernández-Arroyo, Salvador, Samarra, Iris, Canela-Capdevila, Marta, Arenas, Meritxell, Zorzano, Antonio, Hernández-Alvarez, María Isabel, Castillo, Daniel del, Paris, Marta, Menendez, Javier A., Camps, Jordi, Joven, Jorge
Published in Clinical nutrition (Edinburgh, Scotland) (01.01.2024)
Published in Clinical nutrition (Edinburgh, Scotland) (01.01.2024)
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Journal Article