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Obesity and pelvic organ prolapse: a systematic review and meta-analysis of observational studies
Giri, Ayush, Hartmann, Katherine E., Hellwege, Jacklyn N., Velez Edwards, Digna R., Edwards, Todd L.
Published in American journal of obstetrics and gynecology (01.07.2017)
Published in American journal of obstetrics and gynecology (01.07.2017)
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Journal Article
A single genetic locus controls both expression of DPEP1/CHMP1A and kidney disease development via ferroptosis
Guan, Yuting, Liang, Xiujie, Ma, Ziyuan, Hu, Hailong, Liu, Hongbo, Miao, Zhen, Linkermann, Andreas, Hellwege, Jacklyn N., Voight, Benjamin F., Susztak, Katalin
Published in Nature communications (23.08.2021)
Published in Nature communications (23.08.2021)
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Journal Article
Mapping the genetic architecture of human traits to cell types in the kidney identifies mechanisms of disease and potential treatments
Sheng, Xin, Guan, Yuting, Ma, Ziyuan, Wu, Junnan, Liu, Hongbo, Qiu, Chengxiang, Vitale, Steven, Miao, Zhen, Seasock, Matthew J., Palmer, Matthew, Shin, Myung K., Duffin, Kevin L., Pullen, Steven S., Edwards, Todd L., Hellwege, Jacklyn N., Hung, Adriana M., Li, Mingyao, Voight, Benjamin F., Coffman, Thomas M., Brown, Christopher D., Susztak, Katalin
Published in Nature genetics (01.09.2021)
Published in Nature genetics (01.09.2021)
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Journal Article
Multi-ancestry meta-analysis of keloids uncovers novel susceptibility loci in diverse populations
Greene, Catherine A., Hampton, Gabrielle, Jaworski, James, Shuey, Megan M., Khan, Atlas, Luo, Yuan, Jarvik, Gail P., Namjou-Khales, Bahram, Edwards, Todd L., Velez Edwards, Digna R., Hellwege, Jacklyn N.
Published in Nature communications (20.08.2025)
Published in Nature communications (20.08.2025)
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Journal Article
Genome-wide meta-analysis identifies novel risk loci for uterine fibroids within and across multiple ancestry groups
Kim, Jeewoo, Williams, Ariel, Noh, Hannah, Jasper, Elizabeth A., Jones, Sarah H., Jaworski, James A., Shuey, Megan M., Ruiz-Narváez, Edward A., Wise, Lauren A., Palmer, Julie R., Connolly, John, Keaton, Jacob M., Denny, Joshua C., Khan, Atlas, Abbass, Mohammad A., Rasmussen-Torvik, Laura J., Kottyan, Leah C., Madhivanan, Purnima, Krupp, Karl, Wei, Wei-Qi, Edwards, Todd L., Velez Edwards, Digna R., Hellwege, Jacklyn N.
Published in Nature communications (06.03.2025)
Published in Nature communications (06.03.2025)
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Journal Article
Genetic predictors of blood pressure traits are associated with preeclampsia
Jasper, Elizabeth A., Hellwege, Jacklyn N., Breeyear, Joseph H., Xiao, Brenda, Jarvik, Gail P., Stanaway, Ian B., Leppig, Kathleen A., Chittoor, Geetha, Hayes, M. Geoffrey, Dikilitas, Ozan, Kullo, Iftikhar J., Holm, Ingrid A., Verma, Shefali Setia, Edwards, Todd L., Velez Edwards, Digna R.
Published in Scientific reports (30.07.2024)
Published in Scientific reports (30.07.2024)
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Journal Article
Genetically-predicted placental gene expression is associated with birthweight and adult body mass index
Jasper, Elizabeth A., Hellwege, Jacklyn N., Piekos, Jacqueline A., Jones, Sarah H., Hartmann, Katherine E., Mautz, Brian, Aronoff, David M., Edwards, Todd L., Edwards, Digna R. Velez
Published in Scientific reports (06.01.2023)
Published in Scientific reports (06.01.2023)
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Journal Article
Evidence of selection as a cause for racial disparities in fibroproliferative disease
Hellwege, Jacklyn N., Torstenson, Eric S., Russell, Shirley B., Edwards, Todd L., Velez Edwards, Digna R.
Published in PloS one (08.08.2017)
Published in PloS one (08.08.2017)
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Journal Article
67 Anti-hypertensives identified as therapeutic candidates for uterine fibroids using genetically informed drug repurposing approaches
Kim, Jeewoo, Khankari, Nikhil K., DeCorte, Joseph A., Hellwege, Jacklyn N., Velez Edwards, Digna R., Edwards, Todd L.
Published in Journal of clinical and translational science (01.04.2025)
Published in Journal of clinical and translational science (01.04.2025)
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Journal Article
430 Genome-wide meta-analysis identifies novel risk loci for uterine fibroids across multiple ancestry groups
Kim, Jeewoo, Williams, Ariel, Noh, Hannah, Shuey, Megan M., Edwards, Todd L., Velez Edwards, Digna R., Hellwege, Jacklyn N.
Published in Journal of clinical and translational science (01.04.2024)
Published in Journal of clinical and translational science (01.04.2024)
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Journal Article
47 Cross-ancestry GWAS meta-analysis of keloids discovers novel susceptibility loci in diverse populations
Greene, Catherine Anne, Hampton, Gabrielle, Jarvik, Gail P., Namjou-Khales, Bahram, Khan, Atlas, Luo, Yuan, Edwards, Todd L., Velez Edwards, Digna R., Hellwege, Jacklyn N.
Published in Journal of clinical and translational science (01.04.2024)
Published in Journal of clinical and translational science (01.04.2024)
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Journal Article
A phenome-wide association study of uterine fibroids reveals a marked burden of comorbidities
Jasper, Elizabeth A., Mautz, Brian S., Hellwege, Jacklyn N., Piekos, Jacqueline A., Jones, Sarah H., Zhang, Yanfei, Torstenson, Eric S., Pendergrass, Sarah A., Lee, Ming Ta Michael, Edwards, Todd L., Velez Edwards, Digna R.
Published in Communications medicine (15.05.2025)
Published in Communications medicine (15.05.2025)
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Journal Article
SMOC2 gene interacts with APOL1 in the development of end-stage kidney disease: A genome-wide association study
Chaudhary, Ninad S., Armstrong, Nicole D., Hidalgo, Bertha A., Gutiérrez, Orlando M., Hellwege, Jacklyn N., Limdi, Nita A., Reynolds, Richard J., Judd, Suzanne E., Nadkarni, Girish N., Lange, Leslie, Winkler, Cheryl A., Kopp, Jeffrey B., Arnett, Donna K., Tiwari, Hemant K., Irvin, Marguerite R.
Published in Frontiers in medicine (28.09.2022)
Published in Frontiers in medicine (28.09.2022)
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Journal Article
Genome-Wide Interaction with Insulin Secretion Loci Reveals Novel Loci for Type 2 Diabetes in African Americans
Keaton, Jacob M., Hellwege, Jacklyn N., Ng, Maggie C. Y., Palmer, Nicholette D., Pankow, James S., Fornage, Myriam, Wilson, James G., Correa, Adolfo, Rasmussen-Torvik, Laura J., Rotter, Jerome I., Chen, Yii-Der I., Taylor, Kent D., Rich, Stephen S., Wagenknecht, Lynne E., Freedman, Barry I., Bowden, Donald W.
Published in PloS one (22.07.2016)
Published in PloS one (22.07.2016)
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Journal Article
Genetic Risk Score Is Associated With Prevalence of Advanced Neoplasms in a Colorectal Cancer Screening Population
Weigl, Korbinian, Thomsen, Hauke, Balavarca, Yesilda, Hellwege, Jacklyn N., Shrubsole, Martha J., Brenner, Hermann
Published in Gastroenterology (New York, N.Y. 1943) (01.07.2018)
Published in Gastroenterology (New York, N.Y. 1943) (01.07.2018)
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Journal Article
Genome-wide linkage and association analysis of cardiometabolic phenotypes in Hispanic Americans
Hellwege, Jacklyn N, Palmer, Nicholette D, Dimitrov, Latchezar, Keaton, Jacob M, Tabb, Keri L, Sajuthi, Satria, Taylor, Kent D, Ng, Maggie C Y, Speliotes, Elizabeth K, Hawkins, Gregory A, Long, Jirong, Ida Chen, Yii-Der, Lorenzo, Carlos, Norris, Jill M, Rotter, Jerome I, Langefeld, Carl D, Wagenknecht, Lynne E, Bowden, Donald W
Published in Journal of human genetics (01.02.2017)
Published in Journal of human genetics (01.02.2017)
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Journal Article
Relationship Between Blood Pressure and Incident Cardiovascular Disease: Linear and Nonlinear Mendelian Randomization Analyses
Malik, Rainer, Georgakis, Marios K., Vujkovic, Marijana, Damrauer, Scott M., Elliott, Paul, Karhunen, Ville, Giontella, Alice, Fava, Cristiano, Hellwege, Jacklyn N., Shuey, Megan M., Edwards, Todd L., Rogne, Tormod, Åsvold, Bjørn O., Brumpton, Ben M., Burgess, Stephen, Dichgans, Martin, Gill, Dipender
Published in Hypertension (Dallas, Tex. 1979) (01.06.2021)
Published in Hypertension (Dallas, Tex. 1979) (01.06.2021)
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Journal Article
Genome-wide polygenic score to predict chronic kidney disease across ancestries
Khan, Atlas, Turchin, Michael C., Patki, Amit, Srinivasasainagendra, Vinodh, Shang, Ning, Nadukuru, Rajiv, Jones, Alana C., Malolepsza, Edyta, Dikilitas, Ozan, Kullo, Iftikhar J., Schaid, Daniel J., Karlson, Elizabeth, Ge, Tian, Meigs, James B., Smoller, Jordan W., Lange, Christoph, Crosslin, David R., Jarvik, Gail P., Bhatraju, Pavan K., Hellwege, Jacklyn N., Chandler, Paulette, Torvik, Laura Rasmussen, Fedotov, Alex, Liu, Cong, Kachulis, Christopher, Lennon, Niall, Abul-Husn, Noura S., Cho, Judy H., Ionita-Laza, Iuliana, Gharavi, Ali G., Chung, Wendy K., Hripcsak, George, Weng, Chunhua, Nadkarni, Girish, Irvin, Marguerite R., Tiwari, Hemant K., Kenny, Eimear E., Limdi, Nita A., Kiryluk, Krzysztof
Published in Nature medicine (01.07.2022)
Published in Nature medicine (01.07.2022)
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Journal Article