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DNA methylation aging clocks: challenges and recommendations
Bell, Christopher G., Lowe, Robert, Adams, Peter D., Baccarelli, Andrea A., Beck, Stephan, Bell, Jordana T., Christensen, Brock C., Gladyshev, Vadim N., Heijmans, Bastiaan T., Horvath, Steve, Ideker, Trey, Issa, Jean-Pierre J., Kelsey, Karl T., Marioni, Riccardo E., Reik, Wolf, Relton, Caroline L., Schalkwyk, Leonard C., Teschendorff, Andrew E., Wagner, Wolfgang, Zhang, Kang, Rakyan, Vardhman K.
Published in Genome Biology (25.11.2019)
Published in Genome Biology (25.11.2019)
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Journal Article
DNA methylation signatures link prenatal famine exposure to growth and metabolism
Tobi, Elmar W., Goeman, Jelle J., Monajemi, Ramin, Gu, Hongcang, Putter, Hein, Zhang, Yanju, Slieker, Roderick C., Stok, Arthur P., Thijssen, Peter E., Müller, Fabian, van Zwet, Erik W., Bock, Christoph, Meissner, Alexander, Lumey, L. H., Eline Slagboom, P., Heijmans, Bastiaan T.
Published in Nature communications (26.11.2014)
Published in Nature communications (26.11.2014)
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Journal Article
Persistent epigenetic differences associated with prenatal exposure to famine in humans
Heijmans, Bastiaan T, Tobi, Elmar W, Stein, Aryeh D, Putter, Hein, Blauw, Gerard J, Susser, Ezra S, Slagboom, P. Eline, Lumey, L.H
Published in Proceedings of the National Academy of Sciences - PNAS (04.11.2008)
Published in Proceedings of the National Academy of Sciences - PNAS (04.11.2008)
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Journal Article
DNA methylation differences after exposure to prenatal famine are common and timing- and sex-specific
Tobi, Elmar W., Lumey, L.H., Talens, Rudolf P., Kremer, Dennis, Putter, Hein, Stein, Aryeh D., Slagboom, P. Eline, Heijmans, Bastiaan T.
Published in Human molecular genetics (01.11.2009)
Published in Human molecular genetics (01.11.2009)
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Journal Article
Functional genomics analysis identifies T and NK cell activation as a driver of epigenetic clock progression
Jonkman, Thomas H., Dekkers, Koen F., Slieker, Roderick C., Grant, Crystal D., Ikram, M. Arfan, van Greevenbroek, Marleen M. J., Franke, Lude, Veldink, Jan H., Boomsma, Dorret I., Slagboom, P. Eline, Consortium, B. I. O. S., Heijmans, Bastiaan T.
Published in Genome Biology (14.01.2022)
Published in Genome Biology (14.01.2022)
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Journal Article
Early gestation as the critical time-window for changes in the prenatal environment to affect the adult human blood methylome
Tobi, Elmar W, Slieker, Roderick C, Stein, Aryeh D, Suchiman, H Eka D, Slagboom, P Eline, van Zwet, Erik W, Heijmans, Bastiaan T, Lumey, LH
Published in International journal of epidemiology (01.08.2015)
Published in International journal of epidemiology (01.08.2015)
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Journal Article
Epigenetic variation during the adult lifespan: cross‐sectional and longitudinal data on monozygotic twin pairs
Talens, Rudolf P., Christensen, Kaare, Putter, Hein, Willemsen, Gonneke, Christiansen, Lene, Kremer, Dennis, Suchiman, H. Eka D., Slagboom, P. Eline, Boomsma, Dorret I., Heijmans, Bastiaan T.
Published in Aging cell (01.08.2012)
Published in Aging cell (01.08.2012)
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Journal Article
Alternative Routes to Induce Naïve Pluripotency in Human Embryonic Stem Cells
Duggal, Galbha, Warrier, Sharat, Ghimire, Sabitri, Broekaert, Dorien, Van der Jeught, Margot, Lierman, Sylvie, Deroo, Tom, Peelman, Luc, Van Soom, Ann, Cornelissen, Ria, Menten, Björn, Mestdagh, Pieter, Vandesompele, Jo, Roost, Matthias, Slieker, Roderick C., Heijmans, Bastiaan T., Deforce, Dieter, De Sutter, Petra, De Sousa Lopes, Susana Chuva, Heindryckx, Björn
Published in Stem cells (Dayton, Ohio) (01.09.2015)
Published in Stem cells (Dayton, Ohio) (01.09.2015)
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Journal Article
DNA Methylation Landscapes of Human Fetal Development
Slieker, Roderick C., Roost, Matthias S., van Iperen, Liesbeth, Suchiman, H. Eka D., Tobi, Elmar W., Carlotti, Françoise, de Koning, Eelco J. P., Slagboom, P. Eline, Heijmans, Bastiaan T., Chuva de Sousa Lopes, Susana M.
Published in PLoS genetics (01.10.2015)
Published in PLoS genetics (01.10.2015)
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Journal Article
Lipid-induced transcriptomic changes in blood link to lipid metabolism and allergic response
Dekkers, Koen F., Slieker, Roderick C., Ioan-Facsinay, Andreea, van Iterson, Maarten, Ikram, M. Arfan, van Greevenbroek, Marleen M. J., Veldink, Jan H., Franke, Lude, Boomsma, Dorret I., Slagboom, P. Eline, Jukema, J. Wouter, Heijmans, Bastiaan T.
Published in Nature communications (01.02.2023)
Published in Nature communications (01.02.2023)
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Journal Article
Adults prenatally exposed to the Dutch Famine exhibit a metabolic signature associated with a broad spectrum of common diseases
Taeubert, M. Jazmin, Kuipers, Thomas B., Zhou, Jiayi, Li, Chihua, Wang, Shuang, Wang, Tian, Tobi, Elmar W., Belsky, Daniel W., Lumey, L. H., Heijmans, Bastiaan T.
Published in BMC medicine (29.07.2024)
Published in BMC medicine (29.07.2024)
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Journal Article
Prenatal Famine and Genetic Variation Are Independently and Additively Associated with DNA Methylation at Regulatory Loci within IGF2/H19
Tobi, Elmar W., Slagboom, P. Eline, van Dongen, Jenny, Kremer, Dennis, Stein, Aryeh D., Putter, Hein, Heijmans, Bastiaan T., Lumey, L. H.
Published in PloS one (30.05.2012)
Published in PloS one (30.05.2012)
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Journal Article
Unified high-resolution immune cell fraction estimation in blood tissue from birth to old age
Guo, Xiaolong, Sulaiman, Mahnoor, Neumann, Alexander, Zheng, Shijie C., Cecil, Charlotte A.M., Teschendorff, Andrew E., Heijmans, Bastiaan T.
Published in Genome medicine (27.05.2025)
Published in Genome medicine (27.05.2025)
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Journal Article
The epigenome: Archive of the prenatal environment
Heijmans, Bastiaan T., Tobi, Elmar W., Lumey, L.H., Slagboom, P. Eline
Published in Epigenetics (16.11.2009)
Published in Epigenetics (16.11.2009)
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Journal Article
Design, measurement and processing of region-specific DNA methylation assays: the mass spectrometry-based method EpiTYPER
Suchiman, H. Eka D., Slieker, Roderick C., Kremer, Dennis, Slagboom, P. Eline, Heijmans, Bastiaan T., Tobi, Elmar W.
Published in Frontiers in genetics (17.09.2015)
Published in Frontiers in genetics (17.09.2015)
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Journal Article
DNA methylation and transcriptional trajectories during human development and reprogramming of isogenic pluripotent stem cells
Roost, Matthias S., Slieker, Roderick C., Bialecka, Monika, van Iperen, Liesbeth, Gomes Fernandes, Maria M., He, Nannan, Suchiman, H. Eka D., Szuhai, Karoly, Carlotti, Françoise, de Koning, Eelco J. P., Mummery, Christine L., Heijmans, Bastiaan T., Chuva de Sousa Lopes, Susana M.
Published in Nature communications (13.10.2017)
Published in Nature communications (13.10.2017)
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Journal Article