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NetTCR-2.0 enables accurate prediction of TCR-peptide binding by using paired TCRα and β sequence data
Montemurro, Alessandro, Schuster, Viktoria, Povlsen, Helle Rus, Bentzen, Amalie Kai, Jurtz, Vanessa, Chronister, William D., Crinklaw, Austin, Hadrup, Sine R., Winther, Ole, Peters, Bjoern, Jessen, Leon Eyrich, Nielsen, Morten
Published in Communications biology (10.09.2021)
Published in Communications biology (10.09.2021)
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Journal Article
DNA barcoded peptide-MHC multimers to measure and monitor minor histocompatibility antigen-specific T cells after allogeneic stem cell transplantation
Fuchs, Kyra J, Göransson, Marcus, Kester, Michel G D, Ettienne, Natasja W, van de Meent, Marian, de Jong, Rob C M, Koster, Eva A S, Halkes, Constantijn J M, Scheeren, Ferenc, Heemskerk, Mirjam H M, van Balen, Peter, Falkenburg, J H Frederik, Hadrup, Sine R, Griffioen, Marieke
Published in Journal for immunotherapy of cancer (09.12.2024)
Published in Journal for immunotherapy of cancer (09.12.2024)
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Journal Article
Lipid Nanoparticles for Delivery of Therapeutic RNA Oligonucleotides
Moss, Keith Henry, Popova, Petya, Hadrup, Sine R, Astakhova, Kira, Taskova, Maria
Published in Molecular pharmaceutics (03.06.2019)
Published in Molecular pharmaceutics (03.06.2019)
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Journal Article
Meta-analysis of tumor- and T cell-intrinsic mechanisms of sensitization to checkpoint inhibition
Litchfield, Kevin, Reading, James L., Puttick, Clare, Thakkar, Krupa, Abbosh, Chris, Bentham, Robert, Watkins, Thomas B.K., Rosenthal, Rachel, Biswas, Dhruva, Rowan, Andrew, Lim, Emilia, Al Bakir, Maise, Turati, Virginia, Guerra-Assunção, José Afonso, Conde, Lucia, Furness, Andrew J.S., Saini, Sunil Kumar, Hadrup, Sine R., Herrero, Javier, Lee, Se-Hoon, Van Loo, Peter, Enver, Tariq, Larkin, James, Hellmann, Matthew D., Turajlic, Samra, Quezada, Sergio A., McGranahan, Nicholas, Swanton, Charles
Published in Cell (04.02.2021)
Published in Cell (04.02.2021)
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Journal Article
Preclinical evaluation of NF-κB-triggered dendritic cells expressing the viral oncogenic driver of Merkel cell carcinoma for therapeutic vaccination
Gerer, Kerstin F., Erdmann, Michael, Hadrup, Sine R., Lyngaa, Rikke, Martin, Lena-Marie, Voll, Reinhard E., Schuler-Thurner, Beatrice, Schuler, Gerold, Schaft, Niels, Hoyer, Stefanie, Dörrie, Jan
Published in Therapeutic advances in medical oncology (01.07.2017)
Published in Therapeutic advances in medical oncology (01.07.2017)
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Journal Article
Clonal neoantigens elicit T cell immunoreactivity and sensitivity to immune checkpoint blockade
McGranahan, Nicholas, Furness, Andrew J. S., Rosenthal, Rachel, Ramskov, Sofie, Lyngaa, Rikke, Saini, Sunil Kumar, Jamal-Hanjani, Mariam, Wilson, Gareth A., Birkbak, Nicolai J., Hiley, Crispin T., Watkins, Thomas B. K., Shafi, Seema, Murugaesu, Nirupa, Mitter, Richard, Akarca, Ayse U., Linares, Joseph, Marafioti, Teresa, Henry, Jake Y., Van Allen, Eliezer M., Miao, Diana, Schilling, Bastian, Schadendorf, Dirk, Garraway, Levi A., Makarov, Vladimir, Rizvi, Naiyer A., Snyder, Alexandra, Hellmann, Matthew D., Merghoub, Taha, Wolchok, Jedd D., Shukla, Sachet A., Wu, Catherine J., Peggs, Karl S., Chan, Timothy A., Hadrup, Sine R., Quezada, Sergio A., Swanton, Charles
Published in Science (American Association for the Advancement of Science) (25.03.2016)
Published in Science (American Association for the Advancement of Science) (25.03.2016)
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Journal Article
High-Throughput Identification of Potential Minor Histocompatibility Antigens by MHC Tetramer-Based Screening: Feasibility and Limitations
Hombrink, Pleun, Hadrup, Sine R., Bakker, Arne, Kester, Michel G. D., Falkenburg, J. H. Frederik, von dem Borne, Peter A., Schumacher, Ton N. M., Heemskerk, Mirjam H. M.
Published in PloS one (05.08.2011)
Published in PloS one (05.08.2011)
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Journal Article
Neoantigen landscape dynamics during human melanoma–T cell interactions
Verdegaal, Els M. E., de Miranda, Noel F. C. C., Visser, Marten, Harryvan, Tom, van Buuren, Marit M., Andersen, Rikke S., Hadrup, Sine R., van der Minne, Caroline E., Schotte, Remko, Spits, Hergen, Haanen, John B. A. G., Kapiteijn, Ellen H. W., Schumacher, Ton N., van der Burg, Sjoerd H.
Published in Nature (London) (04.08.2016)
Published in Nature (London) (04.08.2016)
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Journal Article
Fundamental immune–oncogenicity trade-offs define driver mutation fitness
Hoyos, David, Zappasodi, Roberta, Schulze, Isabell, Sethna, Zachary, de Andrade, Kelvin César, Bajorin, Dean F., Bandlamudi, Chaitanya, Callahan, Margaret K., Funt, Samuel A., Hadrup, Sine R., Holm, Jeppe S., Rosenberg, Jonathan E., Shah, Sohrab P., Vázquez-García, Ignacio, Weigelt, Britta, Wu, Michelle, Zamarin, Dmitriy, Campitelli, Laura F., Osborne, Edward J., Klinger, Mark, Robins, Harlan S., Khincha, Payal P., Savage, Sharon A., Balachandran, Vinod P., Wolchok, Jedd D., Hellmann, Matthew D., Merghoub, Taha, Levine, Arnold J., Łuksza, Marta, Greenbaum, Benjamin D.
Published in Nature (London) (02.06.2022)
Published in Nature (London) (02.06.2022)
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Journal Article
T cell receptor fingerprinting enables in-depth characterization of the interactions governing recognition of peptide–MHC complexes
Bentzen, Amalie K, Such, Lina, Jensen, Kamilla K, Marquard, Andrea M, Jessen, Leon E, Miller, Natalie J, Church, Candice D, Lyngaa, Rikke, Koelle, David M, Becker, Jürgen C, Linnemann, Carsten, Schumacher, Ton N M, Marcatili, Paolo, Nghiem, Paul, Nielsen, Morten, Hadrup, Sine R
Published in Nature biotechnology (01.12.2018)
Published in Nature biotechnology (01.12.2018)
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Journal Article
CD8 T-cell Responses against Cyclin B1 in Breast Cancer Patients with Tumors Overexpressing p53
Sørensen, Rikke Bæk, Andersen, Rikke Sick, Svane, Inge Marie, Engell-Noerregaard, Lotte, Hadrup, Sine R., Balslev, Eva, Andersen, Mads Hald, Straten, Per thor
Published in Clinical cancer research (01.03.2009)
Published in Clinical cancer research (01.03.2009)
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Journal Article
Pancreatic cancer–restricted cryptic antigens are targets for T cell recognition
Ely, Zackery A., Kulstad, Zachary J., Gunaydin, Gurcan, Addepalli, Sudarsana, Verzani, Eva K., Casarrubios, Marta, Clauser, Karl R., Wang, Xilin, Lippincott, Isabelle E., Louvet, Cedric, Schmitt, Thomas, Kapner, Kevin S., Agus, Miles P., Hennessey, Connor J., Cleary, James M., Hadrup, Sine R., Klaeger, Susan, Su, Jennifer, Jaeger, Alex M., Wolpin, Brian M., Raghavan, Srivatsan, Smith, Eric L., Greenberg, Philip D., Aguirre, Andrew J., Abelin, Jennifer G., Carr, Steven A., Jacks, Tyler, Freed-Pastor, William A.
Published in Science (American Association for the Advancement of Science) (08.05.2025)
Published in Science (American Association for the Advancement of Science) (08.05.2025)
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Journal Article
Interferon-α promotes HLA-B-restricted presentation of conventional and alternative antigens in human pancreatic β-cells
Carré, Alexia, Samassa, Fatoumata, Zhou, Zhicheng, Perez-Hernandez, Javier, Lekka, Christiana, Manganaro, Anthony, Oshima, Masaya, Liao, Hanqing, Parker, Robert, Nicastri, Annalisa, Brandao, Barbara, Colli, Maikel L., Eizirik, Decio L., Aluri, Jahnavi, Patel, Deep, Göransson, Marcus, Burgos Morales, Orlando, Anderson, Amanda, Landry, Laurie, Kobaisi, Farah, Scharfmann, Raphael, Marselli, Lorella, Marchetti, Piero, You, Sylvaine, Nakayama, Maki, Hadrup, Sine R., Kent, Sally C., Richardson, Sarah J., Ternette, Nicola, Mallone, Roberto
Published in Nature communications (17.01.2025)
Published in Nature communications (17.01.2025)
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Journal Article
Stereotactic ablative body radiotherapy (SABR) combined with immunotherapy (L19-IL2) versus standard of care in stage IV NSCLC patients, ImmunoSABR: a multicentre, randomised controlled open-label phase II trial
Lieverse, Relinde I. Y., Van Limbergen, Evert J., Oberije, Cary J. G., Troost, Esther G. C., Hadrup, Sine R., Dingemans, Anne-Marie C., Hendriks, Lizza E. L., Eckert, Franziska, Hiley, Crispin, Dooms, Christophe, Lievens, Yolande, de Jong, Monique C., Bussink, Johan, Geets, Xavier, Valentini, Vincenzo, Elia, Giuliano, Neri, Dario, Billiet, Charlotte, Abdollahi, Amir, Pasquier, David, Boisselier, Pierre, Yaromina, Ala, De Ruysscher, Dirk, Dubois, Ludwig J., Lambin, Philippe
Published in BMC cancer (15.06.2020)
Published in BMC cancer (15.06.2020)
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Journal Article
Author Correction: Fundamental immune–oncogenicity trade-offs define driver mutation fitness
Hoyos, David, Zappasodi, Roberta, Schulze, Isabell, Sethna, Zachary, de Andrade, Kelvin César, Bajorin, Dean F., Bandlamudi, Chaitanya, Callahan, Margaret K., Funt, Samuel A., Hadrup, Sine R., Holm, Jeppe S., Rosenberg, Jonathan E., Shah, Sohrab P., Vázquez-García, Ignacio, Weigelt, Britta, Wu, Michelle, Zamarin, Dmitriy, Campitelli, Laura F., Osborne, Edward J., Klinger, Mark, Robins, Harlan S., Khincha, Payal P., Savage, Sharon A., Balachandran, Vinod P., Wolchok, Jedd D., Hellmann, Matthew D., Merghoub, Taha, Levine, Arnold J., Łuksza, Marta, Greenbaum, Benjamin D.
Published in Nature (London) (16.06.2022)
Published in Nature (London) (16.06.2022)
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Journal Article
Merkel cell polyomavirus-specific and CD39+CLA+ CD8 T cells as blood-based predictive biomarkers for PD-1 blockade in Merkel cell carcinoma
Ryu, Heeju, Bi, Timothy M., Pulliam, Thomas H., Sarkar, Korok, Church, Candice D., Kumar, Nandita, Mayer-Blackwell, Koshlan, Jani, Saumya, Ramchurren, Nirasha, Hansen, Ulla K., Hadrup, Sine R., Fling, Steven P., Koelle, David M., Nghiem, Paul, Newell, Evan W.
Published in Cell reports. Medicine (20.02.2024)
Published in Cell reports. Medicine (20.02.2024)
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Journal Article
Discovering naturally processed antigenic determinants that confer protective T cell immunity
Gilchuk, Pavlo, Spencer, Charles T., Conant, Stephanie B., Hill, Timothy, Gray, Jennifer J., Niu, Xinnan, Zheng, Mu, Erickson, John J., Boyd, Kelli L., McAfee, K. Jill, Oseroff, Carla, Hadrup, Sine R., Bennink, Jack R., Hildebrand, William, Edwards, Kathryn M., Crowe, James E., Williams, John V., Buus, Søren, Sette, Alessandro, Schumacher, Ton N.M., Link, Andrew J., Joyce, Sebastian
Published in The Journal of clinical investigation (01.05.2013)
Published in The Journal of clinical investigation (01.05.2013)
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Journal Article
Conditional ligands for Asian HLA variants facilitate the definition of CD8+ T‐cell responses in acute and chronic viral diseases
Chang, Cynthia X. L., Tan, Anthony T., Or, Ming Yan, Toh, Kai Yee, Lim, Pei Yiing, Chia, Adeline S. E., Froesig, Thomas M., Nadua, Karen D., Oh, Hsueh‐Ling J., Leong, Hoe Nam, Hadrup, Sine R., Gehring, Adam J., Tan, Yee‐Joo, Bertoletti, Antonio, Grotenbreg, Gijsbert M.
Published in European journal of immunology (01.04.2013)
Published in European journal of immunology (01.04.2013)
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Journal Article
Hierarchical Bayesian mixture modelling for antigen-specific T-cell subtyping in combinatorially encoded flow cytometry studies
Lin, Lin, Chan, Cliburn, Hadrup, Sine R., Froesig, Thomas M., Wang, Quanli, West, Mike
Published in Statistical applications in genetics and molecular biology (01.06.2013)
Published in Statistical applications in genetics and molecular biology (01.06.2013)
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Journal Article