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TDP-43 pathology disrupts nuclear pore complexes and nucleocytoplasmic transport in ALS/FTD
Chou, Ching-Chieh, Zhang, Yi, Umoh, Mfon E., Vaughan, Spencer W., Lorenzini, Ileana, Liu, Feilin, Sayegh, Melissa, Donlin-Asp, Paul G., Chen, Yu Han, Duong, Duc M., Seyfried, Nicholas T., Powers, Maureen A., Kukar, Thomas, Hales, Chadwick M., Gearing, Marla, Cairns, Nigel J., Boylan, Kevin B., Dickson, Dennis W., Rademakers, Rosa, Zhang, Yong-Jie, Petrucelli, Leonard, Sattler, Rita, Zarnescu, Daniela C., Glass, Jonathan D., Rossoll, Wilfried
Published in Nature neuroscience (01.02.2018)
Published in Nature neuroscience (01.02.2018)
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Journal Article
Intraspinal neural stem cell transplantation in amyotrophic lateral sclerosis: Phase 1 trial outcomes
Feldman, Eva L., Boulis, Nicholas M., Hur, Junguk, Johe, Karl, Rutkove, Seward B., Federici, Thais, Polak, Meraida, Bordeau, Jane, Sakowski, Stacey A., Glass, Jonathan D.
Published in Annals of neurology (01.03.2014)
Published in Annals of neurology (01.03.2014)
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Journal Article
Integrated proteomics reveals brain-based cerebrospinal fluid biomarkers in asymptomatic and symptomatic Alzheimer’s disease
Higginbotham, Lenora, Ping, Lingyan, Dammer, Eric B., Duong, Duc M., Zhou, Maotian, Gearing, Marla, Hurst, Cheyenne, Glass, Jonathan D., Factor, Stewart A., Johnson, Erik C. B., Hajjar, Ihab, Lah, James J., Levey, Allan I., Seyfried, Nicholas T.
Published in Science advances (01.10.2020)
Published in Science advances (01.10.2020)
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Journal Article
A proteomic network approach across the ALS‐FTD disease spectrum resolves clinical phenotypes and genetic vulnerability in human brain
Umoh, Mfon E, Dammer, Eric B, Dai, Jingting, Duong, Duc M, Lah, James J, Levey, Allan I, Gearing, Marla, Glass, Jonathan D, Seyfried, Nicholas T
Published in EMBO molecular medicine (01.01.2018)
Published in EMBO molecular medicine (01.01.2018)
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Journal Article
ATXN2 intermediate expansions in amyotrophic lateral sclerosis
Glass, Jonathan D, Dewan, Ramita, Ding, Jinhui, Gibbs, J Raphael, Dalgard, Clifton, Keagle, Pamela J, Shankaracharya, García-Redondo, Alberto, Traynor, Bryan J, Chia, Ruth, Landers, John E
Published in Brain (London, England : 1878) (27.08.2022)
Published in Brain (London, England : 1878) (27.08.2022)
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Journal Article
Sporadic ALS induced pluripotent stem cell derived neurons reveal hallmarks of TDP-43 loss of function
Rothstein, Jeffrey D., Keeley, Olivia, Warlick, Caroline, Miller, Timothy M., Ly, Cindy V., Glass, Jonathan D., Coyne, Alyssa N.
Published in Nature communications (02.08.2025)
Published in Nature communications (02.08.2025)
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Journal Article
Defining SOD1 ALS natural history to guide therapeutic clinical trial design
Bali, Taha, Self, Wade, Liu, Jingxia, Siddique, Teepu, Wang, Leo H, Bird, Thomas D, Ratti, Elena, Atassi, Nazem, Boylan, Kevin B, Glass, Jonathan D, Maragakis, Nicholas J, Caress, James B, McCluskey, Leo F, Appel, Stanley H, Wymer, James P, Gibson, Summer, Zinman, Lorne, Mozaffar, Tahseen, Callaghan, Brian, McVey, April L, Jockel-Balsarotti, Jennifer, Allred, Peggy, Fisher, Elena R, Lopate, Glenn, Pestronk, Alan, Cudkowicz, Merit E, Miller, Timothy M
Published in Journal of neurology, neurosurgery and psychiatry (01.02.2017)
Published in Journal of neurology, neurosurgery and psychiatry (01.02.2017)
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Journal Article
Distinct conformers of transmissible misfolded SOD1 distinguish human SOD1-FALS from other forms of familial and sporadic ALS
Ayers, Jacob I., Diamond, Jeffrey, Sari, Adriana, Fromholt, Susan, Galaleldeen, Ahmad, Ostrow, Lyle W., Glass, Jonathan D., Hart, P. John, Borchelt, David R.
Published in Acta neuropathologica (01.12.2016)
Published in Acta neuropathologica (01.12.2016)
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Journal Article
Longitudinal biomarkers in amyotrophic lateral sclerosis
Huang, Fen, Zhu, Yuda, Hsiao‐Nakamoto, Jennifer, Tang, Xinyan, Dugas, Jason C., Moscovitch‐Lopatin, Miriam, Glass, Jonathan D., Brown, Robert H., Ladha, Shafeeq S., Lacomis, David, Harris, Jeffrey M., Scearce‐Levie, Kimberly, Ho, Carole, Bowser, Robert, Berry, James D.
Published in Annals of clinical and translational neurology (01.07.2020)
Published in Annals of clinical and translational neurology (01.07.2020)
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Journal Article
Localization of a toxic form of superoxide dismutase 1 protein to pathologically affected tissues in familial ALS
Brotherton, Terrell E, Li, Yingjie, Cooper, Deborah, Gearing, Marla, Julien, Jean-Pierre, Rothstein, Jeffrey D, Boylan, Kevin, Glass, Jonathan D
Published in Proceedings of the National Academy of Sciences - PNAS (03.04.2012)
Published in Proceedings of the National Academy of Sciences - PNAS (03.04.2012)
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Journal Article
Aggregates of Small Nuclear Ribonucleic Acids (snRNAs) in Alzheimer's Disease
Hales, Chadwick M., Dammer, Eric B., Diner, Ian, Yi, Hong, Seyfried, Nicholas T., Gearing, Marla, Glass, Jonathan D., Montine, Thomas J., Levey, Allan I., Lah, James J.
Published in Brain pathology (Zurich, Switzerland) (01.07.2014)
Published in Brain pathology (Zurich, Switzerland) (01.07.2014)
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Journal Article
SOD1 targeted to the mitochondrial intermembrane space prevents motor neuropathy in the Sod1 knockout mouse
Fischer, Lindsey R., Igoudjil, Anissa, Magrané, Jordi, Li, Yingjie, Hansen, Jason M., Manfredi, Giovanni, Glass, Jonathan D.
Published in Brain (London, England : 1878) (01.01.2011)
Published in Brain (London, England : 1878) (01.01.2011)
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Journal Article
Amyotrophic lateral sclerosis is a distal axonopathy: evidence in mice and man
Fischer, Lindsey R., Culver, Deborah G., Tennant, Philip, Davis, Albert A., Wang, Minsheng, Castellano-Sanchez, Amilcar, Khan, Jaffar, Polak, Meraida A., Glass, Jonathan D.
Published in Experimental neurology (01.02.2004)
Published in Experimental neurology (01.02.2004)
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Journal Article
Fibroblast bioenergetics to classify amyotrophic lateral sclerosis patients
Konrad, Csaba, Kawamata, Hibiki, Bredvik, Kirsten G., Arreguin, Andrea J., Cajamarca, Steven A., Hupf, Jonathan C., Ravits, John M., Miller, Timothy M., Maragakis, Nicholas J., Hales, Chadwick M., Glass, Jonathan D., Gross, Steven, Mitsumoto, Hiroshi, Manfredi, Giovanni
Published in Molecular neurodegeneration (24.10.2017)
Published in Molecular neurodegeneration (24.10.2017)
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Journal Article
Cellular toxicity of mutant SOD1 protein is linked to an easily soluble, non-aggregated form in vitro
Brotherton, Terrell E., Li, Yingjie, Glass, Jonathan D.
Published in Neurobiology of disease (01.01.2013)
Published in Neurobiology of disease (01.01.2013)
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Journal Article
Toward a generalizable machine learning workflow for neurodegenerative disease staging with focus on neurofibrillary tangles
Vizcarra, Juan C., Pearce, Thomas M., Dugger, Brittany N., Keiser, Michael J., Gearing, Marla, Crary, John F., Kiely, Evan J., Morris, Meaghan, White, Bartholomew, Glass, Jonathan D., Farrell, Kurt, Gutman, David A.
Published in Acta neuropathologica communications (18.12.2023)
Published in Acta neuropathologica communications (18.12.2023)
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Journal Article