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MONARCH 3: Abemaciclib As Initial Therapy for Advanced Breast Cancer
Goetz, Matthew P., Toi, Masakazu, Campone, Mario, Sohn, Joohyuk, Paluch-Shimon, Shani, Huober, Jens, Park, In Hae, Trédan, Olivier, Chen, Shin-Cheh, Manso, Luis, Freedman, Orit C., Garnica Jaliffe, Georgina, Forrester, Tammy, Frenzel, Martin, Barriga, Susana, Smith, Ian C., Bourayou, Nawel, Di Leo, Angelo
Published in Journal of clinical oncology (10.11.2017)
Published in Journal of clinical oncology (10.11.2017)
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Journal Article
MONARCH 3 final PFS: a randomized study of abemaciclib as initial therapy for advanced breast cancer
Johnston, Stephen, Martin, Miguel, Di Leo, Angelo, Im, Seock-Ah, Awada, Ahmad, Forrester, Tammy, Frenzel, Martin, Hardebeck, Molly C., Cox, Joanne, Barriga, Susana, Toi, Masakazu, Iwata, Hiroji, Goetz, Matthew P.
Published in NPJ breast cancer (17.01.2019)
Published in NPJ breast cancer (17.01.2019)
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Journal Article
A first-in-human phase I study of the oral Notch inhibitor, LY900009, in patients with advanced cancer
Pant, Shubham, Jones, Suzanne F., Kurkjian, Carla D., Infante, Jeffrey R., Moore, Kathleen N., Burris, Howard A., McMeekin, Donald S., Benhadji, Karim A., Patel, Bharvin K.R., Frenzel, Martin J., Kursar, Jonathan D., Zamek-Gliszczynski, Maciej J., Yuen, Eunice S.M., Chan, Edward M., Bendell, Johanna C.
Published in European journal of cancer (1990) (01.03.2016)
Published in European journal of cancer (1990) (01.03.2016)
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Journal Article
MONARCH 2: Abemaciclib in Combination With Fulvestrant in Women With HR+/HER2− Advanced Breast Cancer Who Had Progressed While Receiving Endocrine Therapy
Sledge, George W., Toi, Masakazu, Neven, Patrick, Sohn, Joohyuk, Inoue, Kenichi, Pivot, Xavier, Burdaeva, Olga, Okera, Meena, Masuda, Norikazu, Kaufman, Peter A., Koh, Han, Grischke, Eva-Maria, Frenzel, Martin, Lin, Yong, Barriga, Susana, Smith, Ian C., Bourayou, Nawel, Llombart-Cussac, Antonio
Published in Journal of clinical oncology (01.09.2017)
Published in Journal of clinical oncology (01.09.2017)
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Journal Article
Abemaciclib Combined With Endocrine Therapy for the Adjuvant Treatment of HR+, HER2−, Node-Positive, High-Risk, Early Breast Cancer (monarchE)
Johnston, Stephen R. D., Harbeck, Nadia, Hegg, Roberto, Toi, Masakazu, Martin, Miguel, Shao, Zhi Min, Zhang, Qing Yuan, Martinez Rodriguez, Jorge Luis, Campone, Mario, Hamilton, Erika, Sohn, Joohyuk, Guarneri, Valentina, Okada, Morihito, Boyle, Frances, Neven, Patrick, Cortés, Javier, Huober, Jens, Wardley, Andrew, Tolaney, Sara M., Cicin, Irfan, Smith, Ian C., Frenzel, Martin, Headley, Desirée, Wei, Ran, San Antonio, Belen, Hulstijn, Maarten, Cox, Joanne, O’Shaughnessy, Joyce, Rastogi, Priya
Published in Journal of clinical oncology (01.12.2020)
Published in Journal of clinical oncology (01.12.2020)
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Journal Article
MONARCH 1, A Phase II Study of Abemaciclib, a CDK4 and CDK6 Inhibitor, as a Single Agent, in Patients with Refractory HR+/HER2− Metastatic Breast Cancer
Dickler, Maura N., Tolaney, Sara M., Rugo, Hope S., Cortés, Javier, Diéras, Véronique, Patt, Debra, Wildiers, Hans, Hudis, Clifford A., O'Shaughnessy, Joyce, Zamora, Esther, Yardley, Denise A., Frenzel, Martin, Koustenis, Andrew, Baselga, José
Published in Clinical cancer research (01.09.2017)
Published in Clinical cancer research (01.09.2017)
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Journal Article
Does treatment efficacy of intra-articular sprifermin on knee osteoarthritis differ between demographic strata - A post-hoc analysis from the FORWARD Phase 2 Randomized Controlled Trial
Eckstein, Felix, Wirth, Wolfgang, Ladel, Christoph, Clemmensen, Casper, Basnet, Sandeep, Frenzel, Martin, Knight, Chris
Published in Osteoarthritis and cartilage (01.04.2025)
Published in Osteoarthritis and cartilage (01.04.2025)
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Journal Article
059 - Does treatment efficacy of intra-articular sprifermin on knee osteoarthritis differ between demographic strata - A post-hoc analysis from the FORWARD Phase 2 Randomized Controlled Trial
Eckstein, Felix, Wirth, Wolfgang, Ladel, Christoph, Clemmensen, Casper, Basnet, Sandeep, Frenzel, Martin, Knight, Chris
Published in Osteoarthritis and cartilage (01.04.2025)
Published in Osteoarthritis and cartilage (01.04.2025)
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Journal Article
Efficacy and Safety of Abemaciclib, an Inhibitor of CDK4 and CDK6, for Patients with Breast Cancer, Non–Small Cell Lung Cancer, and Other Solid Tumors
Patnaik, Amita, Rosen, Lee S., Tolaney, Sara M., Tolcher, Anthony W., Goldman, Jonathan W., Gandhi, Leena, Papadopoulos, Kyriakos P., Beeram, Muralidhar, Rasco, Drew W., Hilton, John F., Nasir, Aejaz, Beckmann, Richard P., Schade, Andrew E., Fulford, Angie D., Nguyen, Tuan S., Martinez, Ricardo, Kulanthaivel, Palaniappan, Li, Lily Q., Frenzel, Martin, Cronier, Damien M., Chan, Edward M., Flaherty, Keith T., Wen, Patrick Y., Shapiro, Geoffrey I.
Published in Cancer discovery (01.07.2016)
Published in Cancer discovery (01.07.2016)
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Journal Article
Abstract CT092: A phase II study of neoadjuvant abemaciclib (LY2835219) in postmenopausal women with hormone receptor positive (HR+), human epidermal growth factor receptor 2 negative (HER2-) breast cancer (neoMONARCH)
Hurvitz, Sara A., Schilder, Jeanne Marie, Frenzel, Martin, Martín, Miguel
Published in Cancer research (Chicago, Ill.) (15.07.2016)
Published in Cancer research (Chicago, Ill.) (15.07.2016)
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Journal Article
Abstract CT040: MONARCH 3: Abemaciclib as initial therapy for patients with HR+, HER2- advanced breast cancer - Results from the preplanned final PFS analysis
Goetz, Matthew P., Martin, Miguel, Leo, Angelo Di, Im, Seock-Ah, Awada, Ahmad, Forrester, Tammy, Frenzel, Martin, Cox, Joanne, Barriga, Susana, Toi, Masakazu, Iwata, Hiroji, Johnston, Stephen
Published in Cancer research (Chicago, Ill.) (01.07.2018)
Published in Cancer research (Chicago, Ill.) (01.07.2018)
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Journal Article
Real-world survival outcomes of heavily pretreated patients with refractory HR+, HER2−metastatic breast cancer receiving single-agent chemotherapy—a comparison with MONARCH 1
Rugo, Hope S., Dieras, Veronique, Cortes, Javier, Patt, Debra, Wildiers, Hans, O’Shaughnessy, Joyce, Zamora, Esther, Yardley, Denise A., Carter, Gebra Cuyun, Sheffield, Kristin M., Li, Li, Andre, Valerie A. M., Li, Xiaohong I., Frenzel, Martin, Huang, Yu-Jing, Dickler, Maura N., Tolaney, Sara M.
Published in Breast cancer research and treatment (01.11.2020)
Published in Breast cancer research and treatment (01.11.2020)
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Journal Article
MONARCH 3: A randomized phase III study of anastrozole or letrozole plus abemaciclib, a CDK4/6 inhibitor, or placebo in first-line treatment of women with HR+, HER2-locoregionally recurrent or metastatic breast cancer (MBC)
Goetz, Matthew P., Toi, Masakazu, Klise, Suzanne, Frenzel, Martin, Bourayou, Nawel, Di Leo, Angelo
Published in Journal of clinical oncology (20.05.2015)
Published in Journal of clinical oncology (20.05.2015)
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Journal Article
Abstract OT1-1-07: A phase III study of abemaciclib (LY2835219) combined with fulvestrant in women with hormone receptor positive (HR+), human epidermal growth factor receptor 2 negative (HER2-) breast cancer (MONARCH 2)
Llombart, Antonio, Toi, Masakazu, Klise, Suzanne R, Frenzel, Martin, Chan, Edward M, Sledge, George W
Published in Cancer research (Chicago, Ill.) (01.05.2015)
Published in Cancer research (Chicago, Ill.) (01.05.2015)
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Journal Article
Prognostic characteristics in hormone receptor-positive advanced breast cancer and characterization of abemaciclib efficacy
Di Leo, Angelo, O’Shaughnessy, Joyce, Sledge, George W., Martin, Miguel, Lin, Yong, Frenzel, Martin, Hardebeck, Molly C., Smith, Ian C., Llombart-Cussac, Antonio, Goetz, Matthew P., Johnston, Stephen
Published in NPJ breast cancer (18.12.2018)
Published in NPJ breast cancer (18.12.2018)
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Journal Article
The association of early toxicity and outcomes for patients treated with abemaciclib
Rugo, Hope S., Sledge, George W., Johnston, Stephen R. D., Goetz, Matthew P., Martin, Miguel, Toi, Masakazu, Forrester, Tammy D, Frenzel, Martin, Cox, Joanne, Barriga, Susana, Tolaney, Sara M.
Published in Journal of clinical oncology (20.05.2018)
Published in Journal of clinical oncology (20.05.2018)
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Journal Article
MONARCH1: Results from a phase II study of abemaciclib, a CDK4 and CDK6 inhibitor, as monotherapy, in patients with HR+/HER2- breast cancer, after chemotherapy for advanced disease
Dickler, Maura N., Tolaney, Sara M., Rugo, Hope S., Cortes, Javier, Diéras, Véronique, Patt, Debra A., Wildiers, Hans, Frenzel, Martin, Koustenis, Andrew, Baselga, Jose
Published in Journal of clinical oncology (20.05.2016)
Published in Journal of clinical oncology (20.05.2016)
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Journal Article
MONARCH 1, a phase 2 study of abemaciclib, a CDK4 and CDK6 inhibitor, as a single agent, in patients with refractory HR+/HER2− metastatic breast cancer
Dickler, Maura N., Tolaney, Sara M., Rugo, Hope S., Cortés, Javier, Diéras, Véronique, Patt, Debra, Wildiers, Hans, Hudis, Clifford A., O’Shaughnessy, Joyce, Zamora, Esther, Yardley, Denise A., Frenzel, Martin, Koustenis, Andrew, Baselga, José
Published in Clinical cancer research (22.05.2017)
Published in Clinical cancer research (22.05.2017)
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Journal Article
MONARCH 2: Abemaciclib in combination with fulvestrant in patients with HR+/HER2- advanced breast cancer who progressed on endocrine therapy
Sledge, George W., Toi, Masakazu, Neven, Patrick, Sohn, Joohyuk, Inoue, Kenichi, Pivot, Xavier B., Burdaeva, Olga Nikolaevna, Okera, Meena, Masuda, Norikazu, Kaufman, Peter A., Koh, Han A., Grischke, Eva-Maria, Frenzel, Martin, Lin, Yong, Barriga, Susana, Smith, Ian C., Bourayou, Nawel, Llombart-Cussac, Antonio
Published in Journal of clinical oncology (20.05.2017)
Published in Journal of clinical oncology (20.05.2017)
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Journal Article
Abstract P5-19-13: Clinical activity of abemaciclib, an oral cell cycle inhibitor, in metastatic breast cancer
Tolaney, Sara M, Rosen, Lee S, Beeram, Muralidhar, Goldman, Jonathan W, Gandhi, Leena, Tolcher, Anthony W, Papadopoulos, Kyriakos P, Rasco, Drew W, Myrand, Scott P, Kulanthaivel, Palaniappan, Andrews, Joan M, Frenzel, Martin, Cronier, Damien M, Chan, Edward M, Flaherty, Keith T, Wen, Patrick Y, Shapiro, Geoffrey I, Patnaik, Amita
Published in Cancer research (Chicago, Ill.) (01.05.2015)
Published in Cancer research (Chicago, Ill.) (01.05.2015)
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Journal Article