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Systematic analysis of tup1 and cyc8 mutants reveals distinct roles for TUP1 and CYC8 and offers new insight into the regulation of gene transcription by the yeast Tup1-Cyc8 complex
Lee, Brenda, Church, Michael, Hokamp, Karsten, Alhussain, Mohamed M., Bamagoos, Atif A., Fleming, Alastair B.
Published in PLoS genetics (11.08.2023)
Published in PLoS genetics (11.08.2023)
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Journal Article
H2B Ubiquitylation Plays a Role in Nucleosome Dynamics during Transcription Elongation
Fleming, Alastair B., Kao, Cheng-Fu, Hillyer, Cory, Pikaart, Michael, Osley, Mary Ann
Published in Molecular cell (11.07.2008)
Published in Molecular cell (11.07.2008)
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Journal Article
Aspergillus fumigatus mitogen-activated protein kinase MpkA is involved in gliotoxin production and self-protection
Alves de Castro, Patrícia, Figueiredo Pinzan, Camila, dos Reis, Thaila Fernanda, Valero, Clara, Van Rhijn, Norman, Menegatti, Carla, de Freitas Migliorini, Ivan Lucas, Bromley, Michael, Fleming, Alastair B., Traynor, Aimee M., Sarikaya-Bayram, Özlem, Bayram, Özgür, Malavazi, Iran, Ebel, Frank, Barbosa, Júlio César Jerônimo, Fill, Taícia, Pupo, Monica Tallarico, Goldman, Gustavo H.
Published in Nature communications (02.01.2024)
Published in Nature communications (02.01.2024)
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Journal Article
Pol II and its associated epigenetic marks are present at Pol III–transcribed noncoding RNA genes
Barski, Artem, Chepelev, Iouri, Liko, Dritan, Cuddapah, Suresh, Fleming, Alastair B, Birch, Joanna, Cui, Kairong, White, Robert J, Zhao, Keji
Published in Nature structural & molecular biology (01.05.2010)
Published in Nature structural & molecular biology (01.05.2010)
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Journal Article
The Pheromone Module SteC-MkkB-MpkB-SteD-HamE Regulates Development, Stress Responses and Secondary Metabolism in Aspergillus fumigatus
Frawley, Dean, Stroe, Maria C., Oakley, Berl R., Heinekamp, Thorsten, Straßburger, Maria, Fleming, Alastair B., Brakhage, Axel A., Bayram, Özgür
Published in Frontiers in microbiology (07.05.2020)
Published in Frontiers in microbiology (07.05.2020)
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Journal Article
Telomeric ORFs (TLOs) in Candida spp. Encode Mediator Subunits That Regulate Distinct Virulence Traits
Haran, John, Boyle, Hannah, Hokamp, Karsten, Yeomans, Tim, Liu, Zhongle, Church, Michael, Fleming, Alastair B., Anderson, Matthew Z., Berman, Judith, Myers, Lawrence C., Sullivan, Derek J., Moran, Gary P.
Published in PLoS genetics (01.10.2014)
Published in PLoS genetics (01.10.2014)
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Journal Article
Putative Membrane Receptors Contribute to Activation and Efficient Signaling of Mitogen-Activated Protein Kinase Cascades during Adaptation of Aspergillus fumigatus to Different Stressors and Carbon Sources
Silva, Lilian Pereira, Frawley, Dean, Assis, Leandro José de, Tierney, Ciara, Fleming, Alastair B., Bayram, Ozgur, Goldman, Gustavo Henrique
Published in mSphere (16.09.2020)
Published in mSphere (16.09.2020)
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Journal Article
H2B ubiquitylation is part of chromatin architecture that marks exon-intron structure in budding yeast
Shieh, Grace S, Pan, Chin-Hua, Wu, Jia-Hong, Sun, Yun-Ju, Wang, Chia-Chang, Hsiao, Wei-Chun, Lin, Chia-Yeh, Tung, Luh, Chang, Tien-Hsien, Fleming, Alastair B, Hillyer, Cory, Lo, Yi-Chen, Berger, Shelley L, Osley, Mary Ann, Kao, Cheng-Fu
Published in BMC genomics (22.12.2011)
Published in BMC genomics (22.12.2011)
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Journal Article
Fluconazole resistance and CDR1 expression in Candida albicans mediated by the hyperactive Tac1-5 transcriptional activator requires Tlo proteins
Lim, Wen Jun, Lee, Brenda, Farrington, Zahra, Abu Alhaija, Abed Alkarem, Fleming, Alastair B., Sullivan, Derek J., Moran, Gary P.
Published in Microbiology (Society for General Microbiology) (01.09.2025)
Published in Microbiology (Society for General Microbiology) (01.09.2025)
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Journal Article
The tetrameric pheromone module SteC‐MkkB‐MpkB‐SteD regulates asexual sporulation, sclerotia formation and aflatoxin production in Aspergillus flavus
Frawley, Dean, Greco, Claudio, Oakley, Berl, Alhussain, Mohamed M., Fleming, Alastair B., Keller, Nancy P., Bayram, Özgür
Published in Cellular microbiology (01.06.2020)
Published in Cellular microbiology (01.06.2020)
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Journal Article
The KdmB-EcoA-RpdA-SntB chromatin complex binds regulatory genes and coordinates fungal development with mycotoxin synthesis
Karahoda, Betim, Pardeshi, Lakhansing, Ulas, Mevlut, Dong, Zhiqiang, Shirgaonkar, Niranjan, Guo, Shuhui, Wang, Fang, Tan, Kaeling, Sarikaya-Bayram, Özlem, Bauer, Ingo, Dowling, Paul, Fleming, Alastair B, Pfannenstiel, Brandon T, Luciano-Rosario, Dianiris, Berger, Harald, Graessle, Stefan, Alhussain, Mohamed M, Strauss, Joseph, Keller, Nancy P, Wong, Koon Ho, Bayram, Özgür
Published in Nucleic acids research (23.09.2022)
Published in Nucleic acids research (23.09.2022)
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Journal Article
The KdmB-EcoA-RpdA-SntB (KERS) chromatin regulatory complex controls development, secondary metabolism and pathogenicity in Aspergillus flavus
Karahoda, Betim, Pfannenstiel, Brandon T., Sarikaya-Bayram, Özlem, Dong, Zhiqiang, Ho Wong, Koon, Fleming, Alastair B., Keller, Nancy P., Bayram, Özgür
Published in Fungal genetics and biology (01.12.2023)
Published in Fungal genetics and biology (01.12.2023)
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Journal Article
The yeast Cyc8–Tup1 complex cooperates with Hda1p and Rpd3p histone deacetylases to robustly repress transcription of the subtelomeric FLO1 gene
Fleming, Alastair B., Beggs, Suzanne, Church, Michael, Tsukihashi, Yoshihiro, Pennings, Sari
Published in Biochimica et biophysica acta (01.11.2014)
Published in Biochimica et biophysica acta (01.11.2014)
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Journal Article
Distinct histone methylation and transcription profiles are established during the development of cellular quiescence in yeast
Young, Conor P., Hillyer, Cory, Hokamp, Karsten, Fitzpatrick, Darren J., Konstantinov, Nikifor K., Welty, Jacqueline S., Ness, Scott A., Werner-Washburne, Margaret, Fleming, Alastair B., Osley, Mary Ann
Published in BMC genomics (26.01.2017)
Published in BMC genomics (26.01.2017)
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Journal Article
The influence of flocculation upon global gene transcription in a yeast CYC8 mutant
Lee, Brenda, Hokamp, Karsten, Alhussain, Mohamed M., Bamagoos, Atif A., Fleming, Alastair B.
Published in Microbial genomics (01.03.2024)
Published in Microbial genomics (01.03.2024)
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Journal Article