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Modulating multi-functional ERK complexes by covalent targeting of a recruitment site in vivo
Kaoud, Tamer S., Johnson, William H., Ebelt, Nancy D., Piserchio, Andrea, Zamora-Olivares, Diana, Van Ravenstein, Sabrina X., Pridgen, Jacey R., Edupuganti, Ramakrishna, Sammons, Rachel, Cano, Micael, Warthaka, Mangalika, Harger, Matthew, Tavares, Clint D. J., Park, Jihyun, Radwan, Mohamed F., Ren, Pengyu, Anslyn, Eric V., Tsai, Kenneth Y., Ghose, Ranajeet, Dalby, Kevin N.
Published in Nature communications (19.11.2019)
Published in Nature communications (19.11.2019)
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Journal Article
Mechanistic studies on covalent assemblies of metal-mediated hemi-aminal ethers
Jo, Hyun Hwa, Edupuganti, Ramakrishna, You, Lei, Dalby, Kevin N., Anslyn, Eric V.
Published in Chemical science (Cambridge) (01.01.2015)
Published in Chemical science (Cambridge) (01.01.2015)
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Journal Article
Computational and Experimental Studies of Inhibitor Design for Aldolase A
Qi, Rui, Walker, Brandon, Jing, Zhifeng, Yu, Maiya, Stancu, Gabriel, Edupuganti, Ramakrishna, Dalby, Kevin N, Ren, Pengyu
Published in The journal of physical chemistry. B (18.07.2019)
Published in The journal of physical chemistry. B (18.07.2019)
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Journal Article
Definition of a Novel Feed-Forward Mechanism for Glycolysis-HIF1α Signaling in Hypoxic Tumors Highlights Aldolase A as a Therapeutic Target
Grandjean, Geoffrey, de Jong, Petrus R., James, Brian P., Koh, Mei Yee, Lemos, Robert, Kingston, John, Aleshin, Alexander, Bankston, Laurie A., Miller, Claudia P., Cho, Eun Jeong, Edupuganti, Ramakrishna, Devkota, Ashwini, Stancu, Gabriel, Liddington, Robert C., Dalby, Kevin N., Powis, Garth
Published in Cancer research (Chicago, Ill.) (15.07.2016)
Published in Cancer research (Chicago, Ill.) (15.07.2016)
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Journal Article
Computational and Experimental Study of Inhibitors Design for Aldolase A
Qi, Rui, Walker, Brandon, Jing, Zhifeng, Yu, Maiya, Stancu, Gabriel, Edupuganti, Ramakrishna, Dalby, Kevin N., Ren, Pengyu
Published in The journal of physical chemistry. B (03.07.2019)
Published in The journal of physical chemistry. B (03.07.2019)
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Journal Article
Synthesis and biological evaluation of pyrido[2,3-d]pyrimidine-2,4-dione derivatives as eEF-2K inhibitors
Edupuganti, Ramakrishna, Wang, Qiantao, Tavares, Clint D.J., Chitjian, Catrina A., Bachman, James L., Ren, Pengyu, Anslyn, Eric V., Dalby, Kevin N.
Published in Bioorganic & medicinal chemistry (01.09.2014)
Published in Bioorganic & medicinal chemistry (01.09.2014)
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Journal Article
Synthesis and applications of masked oxo-sulfinamides in asymmetric synthesis
Edupuganti, Ramakrishna, Davis, Franklin A
Published in Organic & biomolecular chemistry (14.07.2012)
Published in Organic & biomolecular chemistry (14.07.2012)
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Journal Article
Discovery of a potent inhibitor of MELK that inhibits expression of the anti-apoptotic protein Mcl-1 and TNBC cell growth
Edupuganti, Ramakrishna, Taliaferro, Juliana M., Wang, Qiantao, Xie, Xuemei, Cho, Eun Jeong, Vidhu, Fnu, Ren, Pengyu, Anslyn, Eric V., Bartholomeusz, Chandra, Dalby, Kevin N.
Published in Bioorganic & medicinal chemistry (01.05.2017)
Published in Bioorganic & medicinal chemistry (01.05.2017)
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Journal Article
Abstract P5-08-14: Maternal embryonic leucine zipper kinase is associated with metastasis in triple-negative breast cancer
Xie, Xuemei, Chauhan, Gaurav B., Edupuganti, Ramakrishna, Kogawa, Takahiro, Park, Jihyun, Tacam, Moises T, Vidhu, Fnu, Liu, Diane D., Taliaferro, Juliana M., Pitner, Mary Kathryn, Shen, Yu, Ueno, Naoto T., Krishnamurthy, Savitri, Hortobagyi, Gabriel N., Tripathy, Debu, Van Laere, Steven J., Bartholomeusz, Geoffrey, Dalby, Kevin, Bartholomeusz, Chandra
Published in Cancer research (Chicago, Ill.) (15.02.2022)
Published in Cancer research (Chicago, Ill.) (15.02.2022)
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Journal Article
Abstract 3872: Targeting multi-functional ERK-protein complexes in vivo
Kaoud, Tamer S., Johnson, William H., Ebelt, Nancy D., Piserchio, Andrea, Zamora-Olivares, Diana, Ravenstein, Sabrina V., Pridgen, Jacey R., Edupuganti, Ramakrishna, Sammons, Rachel, Cano, Micael, Warthaka, Mangalika, Ren, Pengyu, Anslyn, Eric V., Tsai, Kenneth Y., Ghose, Ranajeet, Dalby, Kevin N.
Published in Cancer research (Chicago, Ill.) (01.07.2019)
Published in Cancer research (Chicago, Ill.) (01.07.2019)
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Journal Article
Synthesis and structural analyses of phenylethynyl-substituted tris(2-pyridylmethyl)amines and their copper() complexes
Lim, Jaebum, Lynch, Vincent M, Edupuganti, Ramakrishna, Ellington, Andrew, Anslyn, Eric V
Published in Dalton transactions : an international journal of inorganic chemistry (28.06.2016)
Published in Dalton transactions : an international journal of inorganic chemistry (28.06.2016)
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Journal Article
Exploring naphthyl-carbohydrazides as inhibitors of influenza A viruses
Barman, Sanmitra, You, Lei, Chen, Ran, Codrea, Vlad, Kago, Grace, Edupuganti, Ramakrishna, Robertus, Jon, Krug, Robert M., Anslyn, Eric V.
Published in European journal of medicinal chemistry (01.01.2014)
Published in European journal of medicinal chemistry (01.01.2014)
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Journal Article
Computational insights into the binding of IN17 inhibitors to MELK
Harger, Matthew, Lee, Ju-Hyeon, Walker, Brandon, Taliaferro, Juliana M., Edupuganti, Ramakrishna, Dalby, Kevin N., Ren, Pengyu
Published in Journal of molecular modeling (01.06.2019)
Published in Journal of molecular modeling (01.06.2019)
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Journal Article
Reversible Covalent Inhibition of eEF-2K by Carbonitriles
Devkota, Ashwini K., Edupuganti, Ramakrishna, Yan, Chunli, Shi, Yue, Jose, Jiney, Wang, Qiantao, Kaoud, Tamer S., Cho, Eun Jeong, Ren, Pengyu, Dalby, Kevin N.
Published in Chembiochem : a European journal of chemical biology (03.11.2014)
Published in Chembiochem : a European journal of chemical biology (03.11.2014)
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Journal Article
Serotonin Analogues as Inhibitors of Breast Cancer Cell Growth
Jose, Jiney, Tavares, Clint D. J, Ebelt, Nancy D, Lodi, Alessia, Edupuganti, Ramakrishna, Xie, Xuemei, Devkota, Ashwini K, Kaoud, Tamer S, Van Den Berg, Carla L, Anslyn, Eric V, Tiziani, Stefano, Bartholomeusz, Chandra, Dalby, Kevin N
Published in ACS medicinal chemistry letters (12.10.2017)
Published in ACS medicinal chemistry letters (12.10.2017)
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Journal Article
Mechanistic studies on covalent assemblies of metal-mediated hemi-aminal ethersElectronic supplementary information (ESI) available. CCDC 1018457. For ESI and crystallographic data in CIF or other electronic format see DOI: 10.1039/c4sc02495h
Jo, Hyun Hwa, Edupuganti, Ramakrishna, You, Lei, Dalby, Kevin N, Anslyn, Eric V
Year of Publication 01.12.2014
Year of Publication 01.12.2014
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Journal Article
c-Jun N-terminal kinase promotes stem cell phenotype in triple-negative breast cancer through up-regulation of Notch1 via activation of c-Jun
Xie, Xuemei, Kaoud, Tamer S., Edupuganti, Ramakrishna, Zhang, Tinghu, Kogawa, Takahiro, Zhao, Yang, Chauhan, Gaurav B., Giannoukos, Dionysios N., Qi, Yuan, Tripathy, Debu, Wang, Jing, Gray, Nathanael S., Dalby, Kevin N., Bartholomeusz, Chandra, Ueno, Naoto T.
Published in Oncogene (12.12.2016)
Published in Oncogene (12.12.2016)
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Journal Article
Abstract 513: Investigating stress-response pathways in pancreatic cancer cells using novel PERK inhibitors
Park, Jihyun, Wang, Qiantao, Kaoud, Tamer S., Tavares, Clint D. J, Edupuganti, Ramakrishna, Ren, Pengyu, Dalby, Kevin N.
Published in Cancer research (Chicago, Ill.) (01.10.2014)
Published in Cancer research (Chicago, Ill.) (01.10.2014)
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Journal Article
Maternal Embryonic Leucine Zipper Kinase is Associated with Metastasis in Triple-negative Breast Cancer
Xie, Xuemei, Chauhan, Gaurav B., Edupuganti, Ramakrishna, Kogawa, Takahiro, Park, Jihyun, Tacam, Moises, Tan, Alex W., Mughees, Mohd, Vidhu, Fnu, Liu, Diane D., Taliaferro, Juliana M., Pitner, Mary Kathryn, Browning, Luke S., Lee, Ju-Hyeon, Bertucci, François, Shen, Yu, Wang, Jian, Ueno, Naoto T., Krishnamurthy, Savitri, Hortobagyi, Gabriel N., Tripathy, Debu, Van Laere, Steven J., Bartholomeusz, Geoffrey, Dalby, Kevin N., Bartholomeusz, Chandra
Published in Cancer research communications (01.06.2023)
Published in Cancer research communications (01.06.2023)
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Journal Article