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Complement C3 Is Activated in Human AD Brain and Is Required for Neurodegeneration in Mouse Models of Amyloidosis and Tauopathy
Wu, Tiffany, Dejanovic, Borislav, Gandham, Vineela D., Gogineni, Alvin, Edmonds, Rose, Schauer, Stephen, Srinivasan, Karpagam, Huntley, Melanie A., Wang, Yuanyuan, Wang, Tzu-Ming, Hedehus, Maj, Barck, Kai H., Stark, Maya, Ngu, Hai, Foreman, Oded, Meilandt, William J., Elstrott, Justin, Chang, Michael C., Hansen, David V., Carano, Richard A.D., Sheng, Morgan, Hanson, Jesse E.
Published in Cell reports (Cambridge) (20.08.2019)
Published in Cell reports (Cambridge) (20.08.2019)
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Journal Article
Complement C1q-dependent excitatory and inhibitory synapse elimination by astrocytes and microglia in Alzheimer’s disease mouse models
Dejanovic, Borislav, Wu, Tiffany, Tsai, Ming-Chi, Graykowski, David, Gandham, Vineela D., Rose, Christopher M., Bakalarski, Corey E., Ngu, Hai, Wang, Yuanyuan, Pandey, Shristi, Rezzonico, Mitchell G., Friedman, Brad A., Edmonds, Rose, De Mazière, Ann, Rakosi-Schmidt, Raphael, Singh, Tarjinder, Klumperman, Judith, Foreman, Oded, Chang, Michael C., Xie, Luke, Sheng, Morgan, Hanson, Jesse E.
Published in Nature aging (01.09.2022)
Published in Nature aging (01.09.2022)
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Journal Article
The Role of the Complement Pathway in Clinical Progression of Geographic Atrophy
Edmonds, Rose, Steffen, Verena, Honigberg, Lee A., Chang, Michael C.
Published in Ophthalmology science (Online) (01.12.2023)
Published in Ophthalmology science (Online) (01.12.2023)
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Journal Article
Alternative Complement Pathway Inhibition by Lampalizumab
Edmonds, Rose, Steffen, Verena, Honigberg, Lee A., Chang, Michael C.
Published in Ophthalmology science (Online) (01.09.2023)
Published in Ophthalmology science (Online) (01.09.2023)
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Journal Article
Impact of Preanalytical Procedures on Complement Biomarkers in Cerebrospinal Fluid and Plasma from Controls and Alzheimer’s Disease Patients
Gutierrez, Johnny, Kurz, Carolin, Sandoval, Cosme, Edmonds, Rose, Bittner, Tobias, Perneczky, Robert, Biever, Anne
Published in Journal of Alzheimer's disease (10.09.2024)
Published in Journal of Alzheimer's disease (10.09.2024)
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Journal Article
The Role of the Complement Pathway in Clinical Progression of Geographic Atrophy: Analysis of the Phase 3 Chroma and Spectri Trials
Edmonds, Rose, MS, Steffen, Verena, MSc, Honigberg, Lee A., PhD, Chang, Michael C., PhD
Published in Ophthalmology science (Online) (2023)
Published in Ophthalmology science (Online) (2023)
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Journal Article