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Intrahepatic Diacylglycerol Content Is Associated With Hepatic Insulin Resistance in Obese Subjects
Magkos, Faidon, Su, Xiong, Bradley, David, Fabbrini, Elisa, Conte, Caterina, Eagon, J. Christopher, Varela, J. Esteban, Brunt, Elizabeth M., Patterson, Bruce W., Klein, Samuel
Published in Gastroenterology (New York, N.Y. 1943) (01.06.2012)
Published in Gastroenterology (New York, N.Y. 1943) (01.06.2012)
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Journal Article
Cellular mechanism of insulin resistance in nonalcoholic fatty liver disease
Kumashiro, Naoki, Erion, Derek M, Zhang, Dongyan, Kahn, Mario, Beddow, Sara A, Chu, Xin, Still, Christopher D, Gerhard, Glenn S, Han, Xianlin, Dziura, James, Petersen, Kitt Falk, Samuel, Varman T, Shulman, Gerald I
Published in Proceedings of the National Academy of Sciences - PNAS (27.09.2011)
Published in Proceedings of the National Academy of Sciences - PNAS (27.09.2011)
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Journal Article
Role of diacylglycerol activation of PKCθ in lipid-induced muscle insulin resistance in humans
Szendroedi, Julia, Yoshimura, Toru, Phielix, Esther, Koliaki, Chrysi, Marcucci, Mellissa, Zhang, Dongyan, Jelenik, Tomas, Müller, Janette, Herder, Christian, Nowotny, Peter, Shulman, Gerald I., Roden, Michael
Published in Proceedings of the National Academy of Sciences - PNAS (01.07.2014)
Published in Proceedings of the National Academy of Sciences - PNAS (01.07.2014)
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Journal Article
Hepatic Diacylglycerol-Associated Protein Kinase Cε Translocation Links Hepatic Steatosis to Hepatic Insulin Resistance in Humans
ter Horst, Kasper W., Gilijamse, Pim W., Versteeg, Ruth I., Ackermans, Mariette T., Nederveen, Aart J., la Fleur, Susanne E., Romijn, Johannes A., Nieuwdorp, Max, Zhang, Dongyan, Samuel, Varman T., Vatner, Daniel F., Petersen, Kitt F., Shulman, Gerald I., Serlie, Mireille J.
Published in Cell reports (Cambridge) (06.06.2017)
Published in Cell reports (Cambridge) (06.06.2017)
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Journal Article
Postprandial Plasma Lipidomics Reveal Specific Alteration of Hepatic-derived Diacylglycerols in Nonalcoholic Fatty Liver Disease
Velenosi, Thomas J., Ben-Yakov, Gil, Podszun, Maren C., Hercun, Julian, Etzion, Ohad, Yang, Shanna, Nadal, Cathy, Haynes-Williams, Vanessa, Huang, Wen-Chun A., González-Hódar, Lila, Brychta, Robert J., Takahashi, Shogo, Akkaraju, Vikas, Krausz, Kristopher W., Walter, Mary, Cai, Hongyi, Walter, Peter J., Muniyappa, Ranganath, Chen, Kong Y., Gonzalez, Frank J., Rotman, Yaron
Published in Gastroenterology (New York, N.Y. 1943) (01.06.2022)
Published in Gastroenterology (New York, N.Y. 1943) (01.06.2022)
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Journal Article
Skeletal muscle and plasma lipidomic signatures of insulin resistance and overweight/obesity in humans
Tonks, Katherine T., Coster, Adelle CF, Christopher, Michael J., Chaudhuri, Rima, Xu, Aimin, Gagnon‐Bartsch, Johann, Chisholm, Donald J., James, David E., Meikle, Peter J., Greenfield, Jerry R., Samocha‐Bonet, Dorit
Published in Obesity (Silver Spring, Md.) (01.04.2016)
Published in Obesity (Silver Spring, Md.) (01.04.2016)
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Journal Article
Augmented frontal cortex diacylglycerol levels in Parkinson’s disease and Lewy Body Disease
Wood, Paul L., Tippireddy, Soumya, Feriante, Joshua, Woltjer, Randall L.
Published in PloS one (07.03.2018)
Published in PloS one (07.03.2018)
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Journal Article
Mechanism by Which Caloric Restriction Improves Insulin Sensitivity in Sedentary Obese Adults
Johnson, Matthew L., Distelmaier, Klaus, Lanza, Ian R., Irving, Brian A., Robinson, Matthew M., Konopka, Adam R., Shulman, Gerald I., Nair, K. Sreekumaran
Published in Diabetes (New York, N.Y.) (01.01.2016)
Published in Diabetes (New York, N.Y.) (01.01.2016)
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Journal Article
Non-targeted lipidomics of CSF and frontal cortex grey and white matter in control, mild cognitive impairment, and Alzheimer’s disease subjects
Wood, Paul L., Barnette, Brooke L., Kaye, Jeffrey A., Quinn, Joseph F., Woltjer, Randall L.
Published in Acta neuropsychiatrica (01.10.2015)
Published in Acta neuropsychiatrica (01.10.2015)
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Journal Article
Ventricular Assist Device Implantation Corrects Myocardial Lipotoxicity, Reverses Insulin Resistance, and Normalizes Cardiac Metabolism in Patients With Advanced Heart Failure
Chokshi, Aalap, Drosatos, Konstantinos, Cheema, Faisal H., Ji, Ruiping, Khawaja, Tuba, Yu, Shuiqing, Kato, Tomoko, Khan, Raffay, Takayama, Hiroo, Knöll, Ralph, Milting, Hendrik, Chung, Christine S., Jorde, Ulrich, Naka, Yoshifumi, Mancini, Donna M., Goldberg, Ira J., Schulze, P. Christian
Published in Circulation (New York, N.Y.) (12.06.2012)
Published in Circulation (New York, N.Y.) (12.06.2012)
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Journal Article
Protein kinase C in cancer: The top five unanswered questions
Cooke, Mariana, Magimaidas, Andrew, Casado‐Medrano, Victoria, Kazanietz, Marcelo G.
Published in Molecular carcinogenesis (01.06.2017)
Published in Molecular carcinogenesis (01.06.2017)
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Journal Article
Interleukin-6-deficient mice develop hepatic inflammation and systemic insulin resistance
Matthews, V. B, Allen, T. L, Risis, S, Chan, M. H. S, Henstridge, D. C, Watson, N, Zaffino, L. A, Babb, J. R, Boon, J, Meikle, P. J, Jowett, J. B, Watt, M. J, Jansson, J.-O, Bruce, C. R, Febbraio, M. A
Published in Diabetologia (01.11.2010)
Published in Diabetologia (01.11.2010)
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Journal Article
Use of lipidomics to investigate sebum dysfunction in juvenile acne[S]
Camera, Emanuela, Ludovici, Matteo, Tortorella, Sara, Sinagra, Jo-Linda, Capitanio, Bruno, Goracci, Laura, Picardo, Mauro
Published in Journal of lipid research (01.06.2016)
Published in Journal of lipid research (01.06.2016)
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Journal Article
Effect of a sustained reduction in plasma free fatty acid concentration on insulin signalling and inflammation in skeletal muscle from human subjects
Liang, Hanyu, Tantiwong, Puntip, Sriwijitkamol, Apiradee, Shanmugasundaram, Karthigayan, Mohan, Sumathy, Espinoza, Sara, DeFronzo, Ralph A., Dubé, John J., Musi, Nicolas
Published in The Journal of physiology (01.06.2013)
Published in The Journal of physiology (01.06.2013)
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Journal Article
Insulin Resistance Is Associated With Higher Intramyocellular Triglycerides in Type I but Not Type II Myocytes Concomitant With Higher Ceramide Content
Coen, Paul M., Dubé, John J., Amati, Francesca, Stefanovic-Racic, Maja, Ferrell, Robert E., Toledo, Frederico G.S., Goodpaster, Bret H.
Published in Diabetes (New York, N.Y.) (01.01.2010)
Published in Diabetes (New York, N.Y.) (01.01.2010)
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Journal Article
Reduced skeletal muscle oxidative capacity and elevated ceramide but not diacylglycerol content in severe obesity
Coen, P.M., Hames, K.C., Leachman, E.M., DeLany, J.P., Ritov, V.B., Menshikova, E.V., Dubé, J.J., Stefanovic‐Racic, M., Toledo, F.G.S., Goodpaster, B.H.
Published in Obesity (Silver Spring, Md.) (01.11.2013)
Published in Obesity (Silver Spring, Md.) (01.11.2013)
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Journal Article
Perilipin 5 fine-tunes lipid oxidation to metabolic demand and protects against lipotoxicity in skeletal muscle
Laurens, Claire, Bourlier, Virginie, Mairal, Aline, Louche, Katie, Badin, Pierre-Marie, Mouisel, Etienne, Montagner, Alexandra, Marette, André, Tremblay, Angelo, Weisnagel, John S., Guillou, Hervé, Langin, Dominique, Joanisse, Denis R., Moro, Cedric
Published in Scientific reports (06.12.2016)
Published in Scientific reports (06.12.2016)
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Journal Article