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Virgin Beta Cells Persist throughout Life at a Neogenic Niche within Pancreatic Islets
van der Meulen, Talitha, Mawla, Alex M., DiGruccio, Michael R., Adams, Michael W., Nies, Vera, Dólleman, Sophie, Liu, Siming, Ackermann, Amanda M., Cáceres, Elena, Hunter, Anna E., Kaestner, Klaus H., Donaldson, Cynthia J., Huising, Mark O.
Published in Cell metabolism (04.04.2017)
Published in Cell metabolism (04.04.2017)
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Journal Article
Comprehensive alpha, beta and delta cell transcriptomes reveal that ghrelin selectively activates delta cells and promotes somatostatin release from pancreatic islets
DiGruccio, Michael R., Mawla, Alex M., Donaldson, Cynthia J., Noguchi, Glyn M., Vaughan, Joan, Cowing-Zitron, Christopher, van der Meulen, Talitha, Huising, Mark O.
Published in Molecular metabolism (Germany) (01.07.2016)
Published in Molecular metabolism (Germany) (01.07.2016)
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Journal Article
Hyperexcitability of Rat Thalamocortical Networks after Exposure to General Anesthesia during Brain Development
DiGruccio, Michael R., Joksimovic, Srdjan, Joksovic, Pavle M., Lunardi, Nadia, Salajegheh, Reza, Jevtovic-Todorovic, Vesna, Beenhakker, Mark P., Goodkin, Howard P., Todorovic, Slobodan M.
Published in The Journal of neuroscience (28.01.2015)
Published in The Journal of neuroscience (28.01.2015)
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Journal Article
Structure of the N-terminal domain of a type B1 G protein-coupled receptor in complex with a peptide ligand
Grace, Christy Rani R, Perrin, Marilyn H, Gulyas, Jozsef, DiGruccio, Michael R, Cantle, Jeffrey P, Rivier, Jean E, Vale, Wylie W, Riek, Roland
Published in Proceedings of the National Academy of Sciences - PNAS (20.03.2007)
Published in Proceedings of the National Academy of Sciences - PNAS (20.03.2007)
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Journal Article
NMR Structure and Peptide Hormone Binding Site of the First Extracellular Domain of a Type B1 G Protein-Coupled Receptor
Christy R. R. Grace, Perrin, Marilyn H., DiGruccio, Michael R., Miller, Charleen L., Rivier, Jean E., Vale, Wylie W., Riek, Roland
Published in Proceedings of the National Academy of Sciences - PNAS (31.08.2004)
Published in Proceedings of the National Academy of Sciences - PNAS (31.08.2004)
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Journal Article
Primary cilia control glucose homeostasis via islet paracrine interactions
Hughes, Jing W., Cho, Jung Hoon, Conway, Hannah E., DiGruccio, Michael R., Ng, Xue Wen, Roseman, Henry F., Abreu, Damien, Urano, Fumihiko, Piston, David W.
Published in Proceedings of the National Academy of Sciences - PNAS (21.04.2020)
Published in Proceedings of the National Academy of Sciences - PNAS (21.04.2020)
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Journal Article
The Role of Free Oxygen Radicals in Lasting Hyperexcitability of Rat Subicular Neurons After Exposure to General Anesthesia During Brain Development
Joksimovic, Srdjan M., DiGruccio, Michael R., Boscolo, Annalisa, Jevtovic-Todorovic, Vesna, Todorovic, Slobodan M.
Published in Molecular neurobiology (01.01.2020)
Published in Molecular neurobiology (01.01.2020)
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Journal Article
The role of T‐type calcium channels in the subiculum: to burst or not to burst?
Joksimovic, Srdjan M., Eggan, Pierce, Izumi, Yukitoshi, Joksimovic, Sonja Lj, Tesic, Vesna, Dietz, Robert M., Orfila, James E., DiGruccio, Michael R., Herson, Paco S., Jevtovic‐Todorovic, Vesna, Zorumski, Charles F., Todorovic, Slobodan M.
Published in The Journal of physiology (01.10.2017)
Published in The Journal of physiology (01.10.2017)
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Journal Article
Reversal of Neuropathic Pain in Diabetes by Targeting Glycosylation of Cav3.2 T-Type Calcium Channels
Orestes, Peihan, Osuru, Hari Prasad, McIntire, William E., Jacus, Megan O., Salajegheh, Reza, Jagodic, Miljen M., Choe, WonJoo, Lee, JeongHan, Lee, Sang-Soo, Rose, Kirstin E., Poiro, Nathan, DiGruccio, Michael R., Krishnan, Katiresan, Covey, Douglas F., Lee, Jung-Ha, Barrett, Paula Q., Jevtovic-Todorovic, Vesna, Todorovic, Slobodan M.
Published in Diabetes (New York, N.Y.) (01.11.2013)
Published in Diabetes (New York, N.Y.) (01.11.2013)
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Journal Article
Distinct Structural and Functional Roles of Conserved Residues in the First Extracellular Domain of Receptors for Corticotropin-releasing Factor and Related G-protein-coupled Receptors
Perrin, Marilyn H., Grace, Christy R.R., DiGruccio, Michael R., Fischer, Wolfgang H., Maji, Samir K., Cantle, Jeffrey P., Smith, Sean, Manning, Gerard, Vale, Wylie W., Riek, Roland
Published in The Journal of biological chemistry (28.12.2007)
Published in The Journal of biological chemistry (28.12.2007)
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Journal Article
Reversal of neuropathic pain in diabetes by targeting glycosylation of Ca(V)3.2 T-type calcium channels
Orestes, Peihan, Osuru, Hari Prasad, McIntire, William E, Jacus, Megan O, Salajegheh, Reza, Jagodic, Miljen M, Choe, Wonjoo, Lee, Jeonghan, Lee, Sang-Soo, Rose, Kirstin E, Poiro, Nathan, Digruccio, Michael R, Krishnan, Katiresan, Covey, Douglas F, Lee, Jung-Ha, Barrett, Paula Q, Jevtovic-Todorovic, Vesna, Todorovic, Slobodan M
Published in Diabetes (New York, N.Y.) (01.11.2013)
Published in Diabetes (New York, N.Y.) (01.11.2013)
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Journal Article
Inhibition of CaV3.2 T-type calcium channels in peripheral sensory neurons contributes to analgesic properties of epipregnanolone
Ayoola, Christine, Hwang, Sung Mi, Hong, Sung Jun, Rose, Kirstin E., Boyd, Christopher, Bozic, Neda, Park, Ji-Yong, Osuru, Hari Prasad, DiGruccio, Michael R., Covey, Douglas F., Jevtovic-Todorovic, Vesna, Todorovic, Slobodan M.
Published in Psychopharmacology (01.09.2014)
Published in Psychopharmacology (01.09.2014)
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Journal Article
Inhibition of T-type calcium current in rat thalamocortical neurons by isoflurane
Eckle, Veit-Simon, DiGruccio, Michael R., Uebele, Victor N., Renger, John J., Todorovic, Slobodan M.
Published in Neuropharmacology (01.08.2012)
Published in Neuropharmacology (01.08.2012)
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Journal Article
Free radical signalling underlies inhibition of CaV3.2 T‐type calcium channels by nitrous oxide in the pain pathway
Orestes, Peihan, Bojadzic, Damir, Lee, JeongHan, Leach, Emily, Salajegheh, Reza, DiGruccio, Michael R., Nelson, Michael T., Todorovic, Slobodan M.
Published in The Journal of physiology (01.01.2011)
Published in The Journal of physiology (01.01.2011)
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Journal Article
A Soluble Mouse Brain Splice Variant of Type 2α Corticotropin-Releasing Factor (CRF) Receptor Binds Ligands and Modulates Their Activity
Chen, Alon M., Perrin, Marilyn H., DiGruccio, Michael R., Vaughan, Joan M., Brar, Bhawanjit K., Arias, Carlos M., Lewis, Kathy A., Rivier, Jean E., Sawchenko, Paul E., Vale, Wylie W.
Published in Proceedings of the National Academy of Sciences - PNAS (15.02.2005)
Published in Proceedings of the National Academy of Sciences - PNAS (15.02.2005)
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Journal Article
Role of Complexin 2 in the regulation of hormone secretion from the islet of Langerhans
Ng, Xue Wen, DiGruccio, Michael R, Kong, Chen, Lee, Jeongmin, Piston, David W
Published in bioRxiv (30.10.2024)
Published in bioRxiv (30.10.2024)
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Journal Article
Paper
BPS2025 - Role of complexin 2 in the regulation of pancreatic islet cell secretion
Ng, Xue Wen, DiGruccio, Michael R., Kong, Chen, Lee, Jeongmin, Piston, David W.
Published in Biophysical journal (13.02.2025)
Published in Biophysical journal (13.02.2025)
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Journal Article